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Dystrophies in Medical News

Creatine Supplement May Help People With Muscular Dystrophies

Creatine, a popular nutritional supplement used by weightlifters and sprinters to improve athletic performance, could lend muscle strength to people with// muscular dystrophies. Muscle strength increased by an average of 8.5 percent among patients taking creatine, compared to those who did no...

March of Dimes Awards $250,000 Prize to Scientists Unraveling the Causes of Muscular Dystrophy

...rophy, as well as childhood conditions such as Duchenne and Becker muscular dystrophies and congenital muscular dystrophy. The March of Dimes Prize is a $250,...r. Campbell and Dr. Kunkel have provided crucial insights into how muscular dystrophies develop -- the critical step needed to develop diagnostic tools and potenti...

Researchers develop DNA 'patch' for canine form of muscular dystrophy

... the Crystal Ball Event of Hampton Roads and the Muscular Dystrophy Association, and the Ministry of Health, Labour, and Welfare of Japan. Muscular dystrophies are a group of disorders causing muscle deterioration and weakness. Duchenne muscular dystrophy occurs almost exclusively in males, affecting 1 in ev...

Updated MD-CARE Act Receives Final Congressional Approval

... over time. -- The development and broad dissemination of care considerations for the muscular dystrophies. -- As promising therapies for muscular dystrophies are identified, they are eligible to be processed through an enhanced clinical infrastructure that "fast tracks" research findings into viable therapi...

Children's Hospital Oakland publishes first of its kind pediatric rehabilitation journal

...ssues will include pediatric medical conditions such as cerebral palsy, traumatic brain injury, spinal cord injury, spina bifida, amputation, muscular dystrophies of all types, stroke, cancer, mental retardation, and developmental delays. "Ultimately, my goal is to contribute scientific knowledge to clinical car...

Investigational drug tested for preventing muscle fiber death in muscular dystrophy

...ommon disease mechanism underlying a number of long-term degenerative disorders, something they plan to study in future research projects. Muscular dystrophies are inherited disorders that mostly affect striated muscle tissue and more commonly occur in boys. This disease results in progressive muscle weakness...

Penn talks at ASCB touch on cancer, neurodegenerative diseases, and MD

...y E. Perlson, J. Ross, K. Wallace, R. Dixit, G. Jeong, R. Kalb, and E. L. Holzbaur of the Department of Physiology. (#1659, Poster, 12/4) Muscular dystrophies (MD): Some MDs are caused by the failure of muscle cells to adhere to a structural scaffold so that they can withstand cell-generated tension. Paxilli...

First Gene Therapy Human Trial For Muscular Dystrophy In Progress

...rapy for DMD is likely to be safe and whether it's likely to result in persistent production of the essential protein in muscle cells. Muscular dystrophies are genetic disorders characterized by progressive muscle wasting and weakness that begin with microscopic changes in the muscle. As muscles degenerat...

Treatment for heart damage in muscular dystrophy may be possible

...prevent heart failures of people suffering from muscular dystrophy. Duchenne muscular dystrophy (DMD) is one of the more common forms of muscular dystrophies that are characterized by muscle enlargement and rapid degeneration of muscles in early life. This disease is linked with the X-chromosomes and thus a...

Different Drug May Help Children With Duchenne Muscular Dystrophy

...uchenne muscular dystrophy (DMD) may// delay the onset and progress of left ventricle dysfunction. DMD is one of the more common forms of muscular dystrophies that are characterized by muscle enlargement and rapid degeneration of muscles in early life. This disease is linked with the X-chromosomes and thus a...
Dystrophies in Medical Technology

Fovea Reports Positive Results with Prednisporin(TM) in Persistent Allergic Conjunctivitis

...ndicate of investors. Fovea has built a project portfolio including internal research programs on dry AMD, glaucoma (neuroprotection) and retinal dystrophies as well as clinical programs underway for such indications as allergic conjunctivitis, diabetic macular edema, retinal vein occlusion, and retinitis p...

PTC Therapeutics Completes Enrollment of Pivotal Trial in Muscular Dystrophy

...ressive muscle disorders that result in the loss of both muscle function and independence. DMD/BMD is perhaps the most prevalent form of the muscular dystrophies and is the most common lethal genetic disorder diagnosed during childhood today. Each year, approximately 20,000 children worldwide are born with DMD...

PTC Therapeutics Announces Data Showing Six-Minute Walk Test Consistently Measures Ambulatory Function in Patients With Duchenne Muscular Dystrophy

...) are progressive muscle disorders that cause the loss of both muscle function and independence. DMD/BMD is perhaps the most prevalent of the muscular dystrophies and is the most common lethal genetic disorder diagnosed during childhood today. Each year, approximately 20,000 children worldwide are born with DMD ...

PTC Therapeutics Announces Initiation of Phase 2b Registration-Directed Clinical Trial of PTC124 in Duchenne/Becker Muscular Dystrophy

...) are progressive muscle disorders that cause the loss of both muscle function and independence. DMD/BMD is perhaps the most prevalent of the muscular dystrophies and is the most common lethal genetic disorder diagnosed during childhood today. Each year, approximately 20,000 children worldwide are born with DMD ...

Fovea Pharmaceuticals Receives Orphan Drug Designation from EC for RdCVF for the Treatment of Retinitis Pigmentosa

...e Private Equity (CAPE). Fovea has built a project portfolio including internal research programs on dry AMD, glaucoma (neuroprotection) and retinal dystrophies as well as clinical programs underway for such indications as macular edema, allergic conjunctivitis, and retinitis pigmentosa. To advance the devel...

PTC Therapeutics Announces Additional Results from Phase 2 Study of PTC124 in Duchenne Muscular Dystrophy

...DMD) is a progressive muscle disorder that causes the loss of both muscle function and independence. DMD is perhaps the most prevalent of the muscular dystrophies and is the most common lethal genetic disorder diagnosed during childhood today. Each year, approximately 20,000 children worldwide are born with DMD ...

PTC Therapeutics Announces Pharmacokinetic and Safety Results from Phase 2 Study of PTC124 in Duchenne Muscular Dystrophy

...DMD) is a progressive muscle disorder that causes the loss of both muscle function and independence. DMD is perhaps the most prevalent of the muscular dystrophies and is the most common lethal genetic disorder diagnosed during childhood today. Each year, approximately 20,000 children worldwide are born with DMD ...
Dystrophies in Medical Products

Focus Night & Day

Description:...orneal pain in the treaent of acute or chronic ocular pathologies such as bullous keratopathy, corneal erosions, entropion, corneal edema, and corneal dystrophies as well as post-surgical conditions resulting from cataract extraction and corneal surgery. Night & Day soft contact lenses for therapeutic use can al...
Company:CIBA Vision
Dystrophies in Medical Dictionary

Muscular Dystrophies

Muscular dystrophy (abbreviated MD) refers to a group of genetic, hereditary ... The best-known type, Duchenne muscular dystrophy (DMD), is inherited in an ... Duchenne muscular dystrophy (DMD) is a severe recessive X-linked form of muscular dystrophy characterized by rapid...
Dystrophies in Biological News

Study may explain exercise-induced fatigue in muscular dystrophies

A University of Iowa study suggests that the prolonged fatigue after mild exercise that occurs in people with many forms of muscular dystrophy is distinct from the inherent muscle weakness caused by the disease. The research, which is published in Nature Advance Online Publication Oct. 26, i...

Sticky protein helps reinforce fragile muscle membranes

...nvestigator. "The findings may also have clinical implications for muscular dystrophies that are caused by abnormal dystroglycan." These congenital muscular dystrophies include Fukuyama Congenital Muscular Dystrophy, Walker-Warburg Syndrome and...

March of Dimes awards $250,000 prize to scientists unraveling the causes of muscular dystrophy

...rophy, as well as childhood conditions such as Duchenne and Becker muscular dystrophies and congenital muscular dystrophy. The March of Dimes Prize is a $250,00...r. Campbell and Dr. Kunkel have provided crucial insights into how muscular dystrophies develop the critical step needed to develop diagnostic tools and potential...

Stabilizing force for good communication between neurons and muscle cells found

...e receptor apparently interact, then hsp90β comes along to help stabilize the relationship. Rapsyn mutations have been implicated in muscular dystrophies including congenital myasthenia gravis. MCG researchers are looking now to see if a mutated rapsyn still interacts with hsp90β. They used a ty...

New clinical trial results show how personalized medicine will alter treatment of genetic disorders

...f patients with Duchenne muscular dystrophy," writes Dr. Hoffman. "But in order to realize the promise of personalized molecular medicine in muscular dystrophies and, ultimately, other disorders, it will be important to re-evaluate current measures of toxicity, efficacy, and marketing that ensure both safety fo...

Massive microRNA scan uncovers leads to treating muscle degeneration

...l Institute, was senior investigator. The disorders include the muscular dystrophies (Duchenne muscular dystrophy, Becker muscular dystrophy, limb girdle muscul...translate the discoveries into treatments. For instance, most muscular dystrophies begin with a known mutation in a master gene, leading to damaged or absent ...

Scientists characterize proteome of human cornea

...acterial, fungal, and viral infections (keratitis) and allergies to various dystrophies including keratoconus. "Corneal damage and disorders account for several...group of inherited corneal disorders including granular and lattice corneal dystrophies are characterized by deposition of insoluble and opaque macromolecules in t...

Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy

...ne into muscle cells in a fairly wide area around the injection site. However, for gene therapy treatments to be successful, particularly for muscular dystrophies where many organs and tissues are affected throughout the body, intramuscular injection is not practical for delivering a corrective gene to the body'...

No small feat: First ever gene therapy success for muscular dystrophy achieved

... treatment can have expansive reach to muscles throughout the body and significantly increase survival. CMD is a group of some 20 inherited muscular dystrophies characterized by progressive and severe muscle wasting and weakness first noticed soon after birth. No effective treatments exist and children usually...

Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy

...ant corrective effect in the mdx mice, which really surprised us." In future research, U-M scientists want to test P188 on mice with other types of dystrophies and see if it works as well when given as injections, rather than infusions. Metzger emphasizes that it is uncertain whether P188 will have any cli...
Dystrophies in Biological Technology

PTC124 Featured at Third Annual Congress of Myology

...) are progressive muscle disorders that cause the loss of both muscle function and independence. DMD/BMD is perhaps the most prevalent of the muscular dystrophies and is the most common lethal genetic disorder diagnosed during childhood today. Each year, approximately 20,000 children worldwide are born with DMD ...

Fovea Pharmaceuticals Completes EUR30M Series B Financing

...it Agricole Private Equity. FOVEA has built a project portfolio including internal research programs on dry AMD, glaucoma (neuroprotection), retinal dystrophies as well as clinical programs underway for such indications as macular edema, allergic conjunctivitis, or retinitis pigmentosa. To advance the develo...

European EMEA Acceptance of Marketing Authorization Application Filing for SNT-MC17 in Friedreich's Ataxia by Santhera

...rkinson's Disease (DPD) in cooperation with Juvantia, the compound's owner. The fifth program comprises SNT-317 (INN: omigapil) in Congenital Muscular dystrophies (CMD), a compound in-licensed from Novartis. The most advanced program, SNT-MC17 in FRDA, is currently in Marketing Authorization Application process ...
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