Correlation Between Bile Duct Obstruction and Ductal Cancer Found

When bile duct cancer cells were placed in the liver of animals with bile duct obstruction, they grew more rapidly than identical cells placed in animals without bile duct// obstruction. In fact, half of the total liver mass of the rats with bile duct obstruction became replaced by cancer cells wit...

Smoking increases potential for metastatic pancreatic cancer

...ine by way of cigarette smoking may increase the likelihood that pancreatic ductal adenocarcinoma will become metastatic, according to researchers from the Ki...steopontin, and high levels of osteopontin have been reported in pancreatic ductal carcinoma (PDA). Dr. Arafat and her research team analyzed PDA samples and ...

Lumenis(R) Presents the SlimLine(TM) GI Laser Fiber: The Latest Advancement in Laser Lithotripsy for Gastroenterology

...i-Center Experience. The presentation reports on 31 patients with an average stone size of 19.3mm and impacted stones in 18 of the 31 patients. ductal clearance was achieved in all 31 patients. (i) The presence of stones in the gallbladder affects approximately 10% of the adult population in the...

New universal breast cancer marker predicts recurrence and clinical outcome

...d online in Cancer Biology & Therapy, the researchers also found that the loss of stromal caveolin-1 in ER-positive non-invasive breast cancers called ductal carcinoma in situ (DCIS) serves as a biomarker for progression to invasive breast cancer. "This marker was highly predictive of development of inv...

Novel gene predicts local recurrence in early onset breast cancer

...rphogenesis, or the orderly development and differentiation of the terminal ductal lobular units (TDLU) in the breast. TDLUs are structures present at the en...d immunohistochemical staining to examine DEAR1 expression in 14 samples of ductal carcinoma in situ (precancerous abnormalities) with adjacent normal epithel...

Sunesis Reports Financial Results for the First Quarter 2009

... in Denver, Colorado. Results from nonclinical translational research studies identified potent voreloxin activity in breast cancer biopsies from both ductal and metastatic tumors. Activity compared favorably with compounds currently in clinical use for the treatment of breast cancer, including cisplatin an...

Novel gene predicts local recurrence in early-onset breast cancer

...rphogenesis, or the orderly development and differentiation of the terminal ductal lobular units (TDLU) in the breast. TDLUs are structures present at the en...d immunohistochemical staining to examine DEAR1 expression in 14 samples of ductal carcinoma in situ (precancerous abnormalities) with adjacent normal epithel...

Popular diabetes treatment could trigger pancreatitis, pancreatic cancer

...e sitagliptin alone, however, the rats had abnormally high rates of cell production in their pancreatic ducts; a few developed an abnormality known as ductal metaplasia, and one developed pancreatitis. But the metformin, trade name Glucophage, seems to counteract sitagliptin's adverse effect. "Th...

Further Testing With Breast-Specific Gamma Imaging (BSGI) Uncovers Additional Cancer in Breast Cancer Patients, Changes Surgical Management

...th Israel Medical Center from 2005 to 2008. A total of 82 patients underwent BSGI for newly diagnosed breast cancer. There were five cases of invasive ductal carcinoma, two DCIS, one LCIS, two papillomas, and eight benign biopsies. One patient proceeded directly to mastectomy and an area of DCIS was found, ...

More women with early stage breast cancer choosing double mastectomies

...reast cancer choosing to have both breasts surgically removed. The rate of contralateral prophylactic mastectomy (CPM) surgery among U.S. women with ductal carcinoma in situ (DCIS) increased by 188 percent between 1998 and 2005, according to Todd Tuttle, M.D., lead researcher on this study. Tuttle is a...

Ductal in Medical Technology

BSGI Posts Higher Sensitivity than Mammography or MRI for the Detection of Ductal Carcinoma In Situ

NEWPORT NEWS, Va., Aug. 10 /PRNewswire/ -- Study results recently published in the Journal of Academic Radiology indicate that Breast-Specific Gamma Imaging (BSGI) provides higher sensitivity for the detection of Ductal Carcinoma In Situ (DCIS) than mammography or MRI and can reliably detect s...

Breast Cancer Clinical Results Show Test Can Differentiate Normal, Early and Later Stage Cancers

...ancer" concluded by stating that "GOS reactivity as measured by adjusted chroma values are significantly different between normal patients, those with ductal Carcenoma In Situ and those with invasive cancer" and that "these results warrant further investigation". "We are extremely pleased that the data wa...

New Mammography Technology Effective in Detecting Breast Cancer

... perform the PEM exam. Of 189 malignant lesions imaged, PEM detected 176 for an overall sensitivity rate of 93 percent. Fifteen percent were ductal carcinoma in situ (DCIS), a noninvasive cancer confined to the ducts of the breast; 85 percent were invasive cancer. PEM successfully detect...

Oncology Drug Development Update - Molecular Profiling Redefines the Nature of Malignancy and Increases the Adoption of Targeted Therapeutics

... is triple negative (Er-, Pgr- and HEr2-) breast cancer, also known as basal-cell cancer. Other classifications include inflammatory breast cancer and ductal carcinoma in situ. Different treatment strategies are in development for each of these tumor types. Similarly, most other malignancies are also underg...

Orion Genomics Announces the Discovery of Novel Breast Cancer Biomarkers

...vel biomarkers that were individually capable of distinguishing early stage ductal breast cancer from normal and benign breast tissue," commented Jared Ordway...ith a clinical sensitivity of 90% and a specificity of 96% for infiltrating ductal breast carcinoma. In addition to identifying biomarkers that might aid in t...

BiPar Begins Phase 2 Study of Lead PARP Inhibitor in Triple-Negative Breast Cancer Based on Overexpression Biomarker Data

...or without the addition of BSI- 201. The research presented in Brussels showed the results of an analysis of PARP gene expression in 169 infiltrating ductal breast cancers through the use of the Gene Logic Inc. (Nasdaq: GLGC ) BioExpress(R) System database. PARP expression was above the 99.9 percent upper...

One-Third of Patients Discontinue Common Breast Cancer Therapy

...treatment of metastatic breast cancer, adjuvant treatment of breast cancer, ductal carcinoma in situ (DCIS), and reduction in breast cancer incidence in high risk women. WARNING - For Women with ductal Carcinoma in Situ (DCIS) and Women at High Risk for Breast Cancer: Serious ...

Ductal in Medical Products

Ductal Lavage, Breast Ductal Lavage

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Cytology, Breast Ductal Lavage

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

CARDIA Patent Ductus Arteriosus Closure Device

Description:...rteriosus. Introduced through standard venous sheaths (10-14F) the device offers a safe and reliable method for the percutaneous closure of persistent ductal shunts ranging in size from 2mm-10mm within the ductus. An integral locking delivery and retrieval mechanism prevents premature delivery of the d...
Company:CARDIA, Inc.

Ductal in Medical Definition

Pathology

...f subspecialties within pathology vary between nations. Anatomical Pathology This mastectomy specimen contains an infiltrating ductal carcinoma of the breast. A pathologist will use immunohistochemistry and fluorescent in-situ hybridization to detect markers which determine the optim...

Ductal in Medical Dictionary

Pancreatic carcinoma

.... exocrine pancreas: Adenocarcinoma · Pancreatic ductal carcinoma . Pancreatoblastoma ... Pancreatic... tumor suppressor gene p16INK4a in pancreatic ductal carcinoma " ... The molecular genetics of pancreatic ductal carcinoma " ... ...

Miliaria

...hich results in the ... In miliaria crystallina, ductal obstruction is most superficial, ... Miliaria...y occur in cool weather ... Miliaria profunda is ductal obstruction at the entrance of the duct into the...chy rashes. ... Miliaria rubra (prickly heat) is ductal obstruction in the mid-epidermis with ... Heat...

Mammography

...eening accuracy. A fact sheet that defines screening mammograms and their advantages ... What happens if mammography leads to the detection of ductal carcinoma in situ (DCIS) ... Diagnostic mammography is used to diagnose breast disease in women who have symptoms. ... With modern ma...

Lavage

...ws the internet yellow pages. Information on ductal lavage , a minimally invasive procedure to help...east cancers originate in cells that line the ... ductal lavage is a new technique to collect cells from ... What are the Possible Benefits and Limitations of ductal Lavage ? ... Compare Cheap Prices for Gastric...

Hypogonadism

...ciency or ... A look at hypogonadism , a hormonal abnormality that often results in male infertility. ... Hypogonadism . Anti Sperm Antibodies. ductal ... Hypogonadism ... INTRODUCTION Hypogonadism in a man refers to a decrease in one or both of the ... Clinical features and diagnosis of ma...

Hyperplasia

...m, or inner lining of the uterus. Hyperplasia occurs when cells within an organ or tissue grow larger and faster than expected. ... If usual ductal hyperplasia is found in your breast biopsy, ... Benign prostatic hyperplasia (BPH) is a condition in which the prostate gland becomes en...

ERCP

...phy ( ERCP ) is a technique that combines the use of endoscopy and fluoroscopy to diagnose and treat certain problems of the biliary or pancreatic ductal systems. Through the... Diagnostic Tests Folder: ERCP (Endoscopic Retrograde Cholangiopancreatography ) Contains patient education fact sheets o...

Carcinoma

...out Carcinoma and related cancers. Learn about different types of Carcinomas : adenocarcinoma, squamous cell, basal cell, renal cell, small cell, ductal ... Expert-reviewed information summary about the treatment of thymoma and thymic carcinoma . ... Thymoma and thymic carcinoma are diseases i...

Ductal in Biological News

Dioxins in food chain linked to breastfeeding ills

...hers also found that dioxin altered the induction of milk-producing genes, which occurs around the ninth day of pregnancy, and decreased the number of ductal branches and mature lobules in the mammary tissue. The timing of dioxin exposure also seemed to be significant, the study noted. For example, when...

'New' estrogen receptor found to be key player in tamoxifen resistance

...kes them much harder to diagnose than the more common cancer type, invasive ductal carcinoma, in which tumors form more discrete lumps. But what the research...ed for gamma estrogen-related receptors in tamoxifen resistance in invasive ductal carcinoma." In addition to its use as a cancer preventive, tamoxifen is ap...

Cells lining milk ducts hold key to spread of common form of breast cancer

...te researchers. The discovery, reported in the May 6 issue of Cancer Cell, may lead to screening tests to determine whether the disease -- known as ductal carcinoma in situ, or DCIS -- is likely to spread beyond the ducts, based on genetic abnormalities in cells in the ducts' lining. And it sets the stag...

Cell response to stress signals predicts tumors in women with common pre-breast cancer

...esponse to cellular stress may predict the likelihood of future tumor formation of the most common, non-invasive form of pre-malignant breast cancer-- ductal carcinoma in situ, or DCIS. This information could potentially be used in a clinical setting to determine which women should receive more or less...

Genetic pathways to curable and incurable forms of pancreatic cancer identified

... Pancreatic ductal adenocarcinoma is an almost uniformly fatal diseas..., a small percentage of patients develop a form of ductal adenocarcinoma associated with cystic lesions that...s a 50 percent long-term survival rate. Why cystic ductal pancreatic cancer behaves differently, despite car...

Gene screen for breast cancer better than pathologist's 'eye'

... on breast fluid samples. The fluid samples, taken from high-risk women or those diagnosed with breast cancer, were obtained through a process called ductal lavage, a saline wash via a catheter threaded through openings in the nipple leading to the vast network of breast ducts. Cytopathologists correct...

Inflammation and drugs to control this activity studied in a variety of tumors sites

...nt for those with negative or weak staining." She noted that increased COX-2 expression has also been seen in an early form of breast cancer called ductal carcinoma in situ, or DCIS. Hartmann said that COX-2 represents a potential target for chemoprevention. Her team plans to expand the test group and wi...

Terahertz imaging may reduce breast cancer surgeries

... were two invasive lobular carcinomas, 14 invasive ductal carcinomas, three mixed invasive ductal and lobular carcinomas, two cases of pure ductal carcinoma in situ and one dense radial scar. In...

Ductal in Biological Technology

Cryoablation of Early Invasive Ductal Breast Cancer With MRI Confirmation Shows Promising Clinical Benefits, According to Study Presented at RSNA

CHICAGO, Dec. 5 /PRNewswire/ -- Early clinical experience with the FDA cleared Visica 2(TM) Treatment System from Sanarus Medical confirms the effectiveness of ultrasound guided cryoablation to completely eradicate small, unifocal Invasive Ductal Breast Cancer (IDC). Initial data from this multi-...

Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance

... renal and prostate cancers. -- Continued early development work in ductal carcinoma in situ (DCIS) breast cancer with the goal of initiating s...e RT-PCR analysis is possible in DCIS that is adjacent to invasive ductal carcinoma of the breast. - Results indicating that multiple...

Novel Diabetes Drug Discovery Has Potential to Reverse Disease

...eptide in a variety of preclinical studies. In these studies, researchers have demonstrated that HIP stimulates insulin secretion in human pancreatic ductal tissue devoid of islets. HIP was also shown to stimulate new islet formation with a 3-fold increase in islet numbers in validated diabetic animal ...

Genomic Health to Present Multiple New Studies at 31st Annual San Antonio Breast Cancer Symposium

...ethods): "Quantitative gene expression analysis using Oncotype DX in ductal carcinoma in situ that is adjacent to invasive ductal carcinoma" Presenter: Rick Baehner, M.D., Helen Diller Family Compre...

Solos Endoscopy, Inc. Applauds American College of Surgeons Review of Advanced Breast Cancer Detection at 94th Annual Clinical Congress

...ican College of Surgeons Clinical Congress in San Francisco, CA. The panel discussed the understanding of the ductal lobular anatomy of the breast and ductal pathologic entities. The Company's current mission is to continue to increase use of its Mammo View(TM) ductoscopy product line in hospitals and breas...

Genomic Health Announces First Quarter 2008 Financial Results and Business Progress

...se of the Oncotype DX 21-gene breast cancer panel, and also seek to identify other genes that may be used for treatment planning in women with ductal carcinoma in situ, or DCIS, which affects approximately 60,000 women per year in the United States. -- Under our collaboration with Pfizer, we re...

Susan G. Komen for the Cure(R) Announces Largest Grants Slate Ever: $100 Million to Speed Delivery of Breast Cancer Discoveries, Cures

...f focus began last year with funding of grants in four specific categories: ductal carcinoma in situ (DCIS), experimental model systems, identification and va...Yale University is using Komen grant money to study the intricacies of ductal carcinoma in situ (DCIS) in order to determine more clearly which case...

JCI table of contents: Dec. 3, 2007

...ion between activated STAT3 and IL-6 expression in primary lung adenocarcinomas. TITLE: IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland AUTHOR CONTACT: Massimiliano Bonaf University of Bologna, Bologna, Italy. Phone: 39-051-636-4009; Fax:...

NeoMatrix Announces Additional Funding for Breakthrough Breast Cancer Screening Test

...ng. The financing will enable an expanded market release of the HALO System, which is designed to test asymptomatic women for the presence of atypical ductal hyperplasia (ADH), a known biomarker that can be a precursor to breast cancer. ADH is often found in the breast years earlier than a lesion might be f...

ESR1 Gene Expression in Oncology and Metabolic Diseases Using the ASCENTATM System Target Validation and Identification of Novel Disease Indications

...rgets as drug candidates. The Diff/X report in Figure 2 shows that ESR1 was elevated (positive fold change) in ERpositive (ER+) infiltrating ductal carcinoma of the breast (the most common histologic variant), relative to normal and fibrocystic breast tissue and to ER-negative (ER-) carcinoma of t...