dosing

Patents Issued Covering Stable Tablet Formulation and Once Daily Dosing Regimen for Kuvan

NOVATO, Calif., July 30, /PRNewswire-FirstCall/ -- BioMarin Pharmaceutical Inc. (Nasdaq: BMRN ) announced today that the United States Patent Office has issued patents covering stable tablet formulation and the approved once daily dosing regimen for Kuvan(R) (sapropterin dihydrochlorid...

Zysolin(TM) Pre-clinical Data Supports Once-a-day Dosing in Humans

AlphaRx's inhaled Tobramycin nanoparticle formulation provides 300% more availability than standard free drug in lung tissue, as demonstrated in a recent animal pharmacokinetic study. MARKHAM, ON, June 18 /PRNewswire-FirstCall/ - AlphaRx (OTC BB:ALRX) is pleased to report a sign...

Synthetic gene circuit allows precise dosing of gene expression

HOUSTON - Researchers have crafted a gene circuit that permits precise tuning of a gene's expression in a cell, an advance that should allow for more accurate analysis of the gene's role in normal and abnormal cellular function. This gene "dosing effect" is achieved by installing a negative fee...

AutoGenomics CYP 2C19 Test Used in Study to Personalize Clopidogrel (Plavix) Dosing in Patients

CARLSBAD, Calif., Jan. 22 /PRNewswire/ -- AutoGenomics, a leader in providing automated molecular testing solutions announced today that its CYP450 2C19 assay was used in a study to demonstrate the value of genetic variants in dosing of the antiplatelet agent...

Optimal Warfarin Dosing Improves Anticoagulation Control

Increasing time within the therapeutic range of utmost importance, study finds TUESDAY, Dec. 30 (HealthDay News) -- While the anticoagulant warfarin can be highly effective in preventing strokes and treating venous thromboembolism, doctors have long struggled with finding the best way ...

Keppra XR(TM) Offers Convenient Dosing For People With Partial Onset Seizures

-- Online survey shows people living with epilepsy often miss a dose of their antiepileptic drug -- UCB continues to build on the company's commitment to patients living with epilepsy through the launch of Keppra XR(TM) (levetiracetam) extended-release tablets -- Keppra XR(TM) is one of ma...

Wide variability in rheumatoid arthritis drug suggests alternative dosing should be considered

Methotrexate (MTX) is commonly used to treat rheumatoid arthritis (RA) and is suggested as the "anchor" drug in treating the disease. Despite its widespread use, the understanding of its mechanism of action and pharmacokinetics is limited. Since joint damage occurs early in the course of RA and is...

Anadys Pharmaceuticals Commences Dosing ANA598 in Hepatitis C Patients in Phase Ib Study

SAN DIEGO, Oct. 28 /PRNewswire-FirstCall/ -- Anadys Pharmaceuticals, Inc. (Nasdaq: ANDS ) announced today that it has initiated dosing ANA598 in patients chronically infected with hepatitis C virus (HCV) in a Phase Ib study. ANA598 is an investigational, oral, non-nucleoside polymerase inhibi...

DNA Direct and Iverson Genetics Announce Partnership to Provide Personalized Patient Reports for Warfarin Dosing Test Results

Interactive Tool Aims to Improve Genetic Healthcare and Educate Patients SAN FRANCISCO and SEATTLE, July 10 /PRNewswire/ -- DNA Direct, Inc. and Iverson Genetic Diagnostics, Inc. today announced that the companies will collaborate to offer personalized reports for individuals receiving Iverson...

New Improved Dosing Approved for Pennsaid

MISSISSAUGA, ON, June 3 /PRNewswire-FirstCall/ - Nuvo Research Inc. (TSX: NRI), a Canadian drug development company focused on the research and development of drug products delivered to and through the skin using its topical and transdermal drug delivery technologies, and Paladin Labs Inc. (TS...

dosing in Medical Technology

FDA Accepts sNDA for Alternative Dosing Regimen for Dacogen(R) (decitabine for injection) to Treat Patients with Myelodysplastic Syndromes (MDS)

WOODCLIFF LAKE, N.J., July 8 /PRNewswire/ -- Eisai Corporation of North America today announced that the U.S. Food and Drug Administration (FDA) has accepted for review the company's supplemental new drug application (sNDA) for an alternative five-day dosing regimen for Dacogen(R) (decitabine for ...

Innocoll Announces Dosing of Last Patient in Second US Phase 3 Clinical Trial to Investigate GENTAMICIN SURGICAL IMPLANT for Prevention of Surgical Site Infections in Colorectal Surgery Patients

ASHBURN, Va., March 19 /PRNewswire/ -- Innocoll, Inc., a privately-held biopharmaceutical company, announced that the last patient has been dosed in the second of two ongoing U.S. phase 3 clinical trials sponsored by its wholly owned subsidiary, Innocoll Technologies Ltd, to investigate CollaRx(R)...

Innocoll Announces Dosing of Last Patient in US Phase 3 Clinical Trial to Investigate GENTAMICIN SURGICAL IMPLANT for Prevention of Surgical Site Infections in Cardiac Surgery Patients

ASHBURN, Va., March 16 /PRNewswire/ -- Innocoll, Inc., a privately-held biopharmaceutical company, announced that the last patient has been dosed in the first of two ongoing U.S. phase 3 clinical trials sponsored by its wholly owned subsidiary, Innocoll Technologies Ltd, to investigate CollaRx(R) ...

Quark Pharmaceuticals Announces Dosing of the First Patient in Phase I/II Clinical Trial for Systemically Delivered siRNA Drug Candidate for Delayed Graft Function

Kidney transplantation to be Quark's second indication with clinical-stage, systemically administered siRNA product candidate FREMONT, Calif., Jan. 8 /PRNewswire/ -- Quark Pharmaceuticals, Inc., a development-stage pharmaceutical company discovering and developing novel RNA interference (RNA...

Synvista Therapeutics Announces First Dosing of SYI-2074 in Clinical Trial for Psoriasis

MONTVALE, N.J., Dec. 15 /PRNewswire-FirstCall/ -- Synvista Therapeutics, Inc. (NYSE Alternext US : SYI) has dosed the first patient in a 30-patient Phase 2 clinical trial of its proprietary topical GPx-mimetic, SYI-2074, in patients with psoriasis. The trial is planned to be a 28-day multi-ce...

SCOLR Pharma Announces Completion of Patient Enrollment and Dosing for Pivotal Clinical Trial Evaluating Extended Release Ibuprofen

Top Line Clinical Results Expected in November 2008 BOTHELL, Wash., Oct. 9 /PRNewswire-FirstCall/ -- SCOLR Pharma, Inc. (Amex: DDD ) announced today the completion of patient enrollment and dosing for the third of its three pivotal trials to evaluate the safety and efficacy of its formulati...

Innocoll Announces Dosing of Last Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-Operative Pain

ASHBURN, Va., Aug. 8 /PRNewswire/ -- Innocoll, Inc., a privately-held biopharmaceutical company, announced that the last patient has been dosed in the first of three ongoing phase 2 clinical trials sponsored by its wholly owned subsidiary, Innocoll Technologies Ltd, to investigate CollaRx(R) B...

Tolerx Initiates Dosing of Otelixizumab, a Novel Type 1 Diabetes Agent, in DEFEND, a Phase 3 Clinical Trial

Milestone achievement triggers $15 million payment from collaborator GlaxoSmithKline CAMBRIDGE, Mass., Aug. 6 /PRNewswire/ -- Tolerx, Inc., a biopharmaceutical company engaged in the discovery and development of novel therapies for immune-mediated diseases, today a...

Nile Therapeutics Announces Dosing in Second Phase Ib Study of CD-NP in Heart Failure Patients

SAN FRANCISCO, July 30 /PRNewswire-FirstCall/ -- Nile Therapeutics, Inc. (Nasdaq: NLTX ), today announced that Mayo Clinic has initiated a Phase Ib, double-blind, placebo-controlled clinical study of CD-NP, a novel chimeric natriuretic peptide, in development for the treatment of acute decomp...

Quark Pharmaceuticals Announces First Patient Dosing by Pfizer in Phase II Trial of RNAi Therapy in Diabetic Macular Edema

Clinical Program Leverages Quark's RNAi Technology FREMONT, Calif., July 30 /PRNewswire/ -- Quark Pharmaceuticals, Inc., a development-stage pharmaceutical company discovering and developing novel RNA interference (RNAi)-based therapeutics, today announced that its partner, Pfizer Inc, initi...

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dosing in Medical Products

RxDrugs™: Drug Dosing Tool Special Mobile/Desktop Bundle

Description: Derived from the trusted, evidence-based AHFS Drug Information database, this continually updated tool provides dosing guidelines on thousands of commonly used brand and generic drugs and now includes nearly 400 integrated weight-based drug dosing calculators....
Company:Skyscape, Inc.

PharmD ToolBox

Description:... PharmD ToolBox is an advanced medical calculator and rapid reference for Emergency, Pediatric dosing and Critical Care for PharmDs. This product is a logical complement to other PDA reference products such as the Daviss Drug Guide, PDR or drug compati...
Company:Medical Wizards™

Davis's Drug Guide for Nurses with Integrated Calculators

Description:... (9th Edition) and has integrated calculation tools with all weight based medications. This product merges many of the advantages of weight based drug dosing calculation with a comprehensive drug reference....
Company:Medical Wizards™

DrDrugs®: Drug Guide for Physicians

Description:...for Physicians - now with over 760 Integrated Calculators - combines the most comprehensive, up-to-date and practical drug resource with built in drug dosing calculation tools for most weight or body surface area based dosing....
Company:Skyscape, Inc.

Davis's Drug Guide for Nurses

Description:...ide for Nurses - now with over 760 Integrated Calculators - combines the most comprehensive, up-to-date and practical drug resource with built in drug dosing calculation tools for most weight or body surface area based dosing....
Company:Skyscape, Inc.

AirLife™ Brand Misty Max 10™ Disposable Nebulizers

Description:...n that delivers high output rates, resulting in faster treatment times and consistent medication delivery. A full 10cc capacity provides medication dosing flexibility. The anti-spill design helps prevent medication waste and allows the unit to be used at an angle to accommodate various patient positions....
Company:Cardinal Health, Inc.

CoStar Paclitaxel-eluting Coronary Stent System

Description:...signed to provide advanced drug delivery capabilities. CONOR Medsystems proprietary technologies allow release profiles to be tailored to optimize the dosing of a drug and to enable the delivery of multiple compounds to various sites in the body. The drug is housed in reservoirs which are the key to customi...
Company:Biotronik GmbH & Co.

002438 AirLife™ Brand Misty Max 10™ Disposable Nebulizers

Description:...n that delivers high output rates, resulting in faster treatment times and consistent medication delivery. A full 10cc capacity provides medication dosing flexibility. The anti-spill design helps prevent medication waste and allows the unit to be used at an angle to accommodate various patient positions....
Company:Cardinal Health, Inc.

002434 AirLife™ Brand Misty Max 10™ Disposable Nebulizers

Description:...hat delivers high output rates, resulting in faster treatment times and consistent medication delivery. A full 10cc capacity provides medication dosing flexibility. The anti-spill design helps prevent medication waste and allows the unit to be used at an angle to accommodate various patient positions....
Company:Cardinal Health, Inc.

PipetBoy Pipettor

Description:...ed. The pipette mount rubber is made of silicone and can be autoclaved. Two dosing knobs enable fine dosing to be carried out when filling and emptying plastic an/or glass pipettes fr...
Company:MIDSCI

dosing in Medical Definition

Ultradian

...ipolar II categories. Ultradian Bipolar Disorder is productively treated by the same mood-stabilizing medications used with Bipolar I and II, though dosing may be difficult due to situational stress and other environmental factors. Researchers are working to understand the brain chemistry basis of moo...

dosing in Medical Dictionary

Thrombolytic therapy

... Intraarterial thrombolytic therapy is a recog- nized treatment option in the setting of acute ... Thrombolytic Therapy Antithrombotic dosing and Algorithms, Information ... Bleeding is the major complication of thrombolytic therapy . ... INTRODUCTION Thrombolytic agents activate pl...

Slit

...0 or more. Low prices on office essentials. Staples that was easy. Talking Points on Sublingual Immunotherapy ( SLIT ) ... is the effective SLIT dosing range? In a comprehensive review of SLIT studies published through October ... Shop for Slit Training at Target.com - Free Shipping on 150,000...

Drug-induced hepatitis

...f the liver that may occur when you take ... You have been diagnosed with drug - induced hepatitis and your symptoms do not ... ... for test dosing for drug - induced hepatitis (described below) may be ... Drug - induced ... TB treatment is drug - induced hepatitis , which has a mortali...

dosing in Biological News

Genetic testing not cost-effective in guiding initial dosing of common blood thinner

CINCINNATINew analyses led by the University of Cincinnati (UC) show that genetic testing used to guide initial dosing of the blood-thinner warfarin may not be cost-effective for typical patients with atrial fibrillation but may be for patients at higher risk for major bleeding. This study is b...

Building memories with actin

...anization of the supporting actin cytoskeleton. However, researchers didn't know what controlled these changes. Rex et al. tackled the question by dosing slices of rat hippocampus with adenosine, a naturally occurring signal that squelches LTP. Adenosine prevents phosphorylation and inactivation of cofi...

Funxional successfully completes initial clinical trial of FX125L, an anti-inflammatory drug with a novel mechanism of action

...s or subject withdrawals were observed. The pharmacokinetics of FX125L was linear over the wide dose range studied and consistent with once-daily oral dosing for patients. We are extremely pleased with the outcome of this initial clinical study with FX125L said Konstantinos Efthymiopoulos, CEO of Funxi...

DuoCort: New chronotherapy for adrenal insufficiency

...se profile of DuoCorts new form of treatment with once-a-day hydrocortisone dosing closely resembles the physiological secretion pattern. The data is publishe...oCort seeks to do so by providing a so-called chronotherapy with once-a-day dosing to further enhance the physiological profile. Link to the abstract in Euro...

Versartis presents positive preclinical data on 2 product candidates at ENDO 09

...ical Versartis compounds have the potential for significantly less frequent dosing and fewer side effects than those products currently on the market or in de...sion data presented today for the first time confirmed our expectation that dosing can be extended from weekly to monthly for our product candidates," said Je...

New tool for next-generation cancer treatments using nanodiamonds

...diamond films currently used in these devices with patterned arrays composed of multiple drugs," Ho says. "This allows high-fidelity spatial tuning of dosing in intelligent devices for comprehensive treatment." "One of the most significant aspects of this work is the Nanofountain Probe's ability to del...

Clinical trials for shingles drug take an important step forward

..." In Phase I trials of FV-100, Inhibitex reported no serious adverse events in healthy volunteers and data supported the potential for once-a-day dosing in future trials. Inhibitex anticipates completing its first Phase II trial of FV-100 in the first half of 2010. Russell H. Plumb, president and ...

Biolex presents Locteron US Phase 2a hepatitis C data at EASL

...by providing a more convenient once-every-two week dosing schedule and by reducing the side effects, includi...nced earlier this week the commencement of patient dosing in the SELECT-2, a Phase 2b trial of Locteron in t...C through a more favorable side-effect profile and dosing convenience compared to existing pegylated interfe...

Ultrasound imaging now possible with a smartphone

...cate the efficacy of the steroids. Measuring these changes in muscle can be accomplished with ultrasound and may allow researchers to optimize steroid dosing to maximize efficacy while minimizing side effects. "The idea is that caregivers, who otherwise have to transport a young person often wheelchair boun...

Gene mutation increases drug toxicity, rejection risk in pediatric kidney transplants

... Clinical Pharmacology and the Pediatric Pharmacology Research Unit at Cincinnati Children's. "This pilot study shows personalized and prospective MMF dosing and monitoring may be feasible to reduce the high incidence of drug toxicity in children without compromising the drug's protective effects against ki...

dosing in Biological Technology

Nile Therapeutics, Inc. Announces Dosing of First Patient in Phase 2 Study of CD-NP for the Treatment of Acute Heart Failure

SAN FRANCISCO, Aug. 4 /PRNewswire-FirstCall/ -- Nile Therapeutics, Inc. (Nasdaq: NLTX ), a company focused on the development of novel therapeutics for heart failure patients, today announced dosing of its first patient in a Phase 2 clinical study of its lead product, CD-NP, for the treatme...

Sinovac Initiates Dosing in Human Clinical Trial of Panflu for Pandemic Influenza A (H1N1)

BEIJING, July 22 /PRNewswire-Asia/ -- Sinovac Biotech Ltd. (NYSE AMEX: SVA ), a leading provider of vaccines in China, today announced that it has initiated dosing today in its clinical trial of various Panflu vaccine candidates for pandemic influenza A (H1N1). Results are expected in Septem...

BioMarin Receives Notice of Allowance for Once Daily Dosing Patent for Kuvan

NOVATO, Calif., March 30 /PRNewswire-FirstCall/ -- BioMarin Pharmaceutical Inc. (Nasdaq: BMRN ) announced today that it has received a notice from the United States Patent Office reporting allowance of claims covering once daily dosing methods for Kuvan(R) (sapropterin dihydrochloride) in the tr...

Anthera Completes Enrollment and Dosing of Varespladib Cardiovascular Trial

HAYWARD, Calif., Jan. 12 /PRNewswire/ -- Anthera Pharmaceuticals, Inc., a privately held biopharmaceutical company developing anti-inflammatory drugs, announced today that it has completed enrollment in its 500 patient FRANCIS (Fewer Recurrent Acute coronary events with Near-term Cardiovascula...

Anadys Pharmaceuticals Commences Dosing ANA773 in Hepatitis C Patients

SAN DIEGO, Oct. 30 /PRNewswire-FirstCall/ -- Anadys Pharmaceuticals, Inc. (Nasdaq: ANDS ) announced today that it has initiated dosing ANA773 in patients chronically infected with hepatitis C virus (HCV) in Part B of a two-part protocol designed to test ANA773 in both healthy volunteers and H...

TorreyPines Therapeutics Begins Dosing in a Phase I Multiple Dose Clinical Trial of NGX426, Oral Prodrug of Tezampanel

LA JOLLA, Calif., Oct. 20 /PRNewswire/ -- TorreyPines Therapeutics, Inc. (Nasdaq: TPTX ) today announced it initiated dosing of the first cohort of subjects in a Phase I multiple dose clinical trial of NGX426, the oral prodrug of its most advanced product candidate, tezampanel. The trial is d...

Innocoll Announces Dosing of First Patient in a Second US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain

ASHBURN, Va., March 13 /PRNewswire-FirstCall/ -- Innocoll, Inc., a privately-held biopharmaceutical company, announced that the second of a series of planned phase 2 clinical trials sponsored by its wholly owned subsidiary, Innocoll Technologies Ltd, to investigate CollaRx(R) BUPIVACAINE SURGI...

Nventa completes enrollment and initial dosing of second cohort in Phase 1 HspE7 safety trial

SAN DIEGO, CA, Dec. 6 /PRNewswire-FirstCall/ - Nventa Biopharmaceuticals Corporation (TSX: NVN) today announced that the Company has completed enrollment and initiated dosing of the second cohort of patients in its Phase 1 dose escalation trial examining the safety of its lead candidate, HspE7...

Cephalon Reinforces Important Prescribing and Dosing Information for FENTORA

FRAZER, Pa., Sept. 13 /PRNewswire-FirstCall/ -- Cephalon, Inc. (Nasdaq: CEPH) today communicated with healthcare professionals to clarify the appropriate patient selection, dosing and administration for FENTORA(R) (fentanyl buccal tablet) [C-II]. The company is sharing this information with th...

Viral Genetics Creates Subsidiary to Develop Cancer Therapy

...AIDS drug based on TNP, called VGV-1, represents a unique approach to treating HIV due to the apparently novel mechanism, low toxicity profile, simple dosing regimen, and short-course of treatment. Online at ww w .viralgenetics.com . SAFE HARBOR FOR FORWARD-LOOKING STATEMENTS: This new...

dosing in Biological Definition

Diabetes mellitus

...food intake is reduced, less insulin is required. A previously satisfactory dosing may be too much if less food is consumed causing a hypoglycemic reaction ...atients on insulin, patient involvement is important in achieving effective dosing and timing. Relying on their own perceptions of symptoms of hyperglycemi...