Higher drug doses needed to defeat tuberculosis, UT Southwestern researchers report
DALLAS July 30, 2009 The typical dose of a medication considered pivotal in treating tuberculosis effectively is much too low to account for modern-day physiques, UT Southwestern Medical Center researchers said.
The finding, reported online and in the August edition of Antimicrobial Agents...
U.S. Expects 160 Million Doses of Swine Flu Vaccine by October
A slowdown in production is hampering efforts, but a nasal spray version might help
THURSDAY, July 23 (HealthDay News) -- 160 million: that's the number of
doses of injectable swine flu vaccine U.S. officials now expect to have on hand by October, with more
doses coming in the form of...
FDA Advisers Urge Smaller Doses of Acetaminophen
The concern is that the drug can cause liver damage, even death, if used improperly
TUESDAY, June 30 (HealthDay News) -- U.S. health advisers recommended Tuesday to lower the maximum dose of over-the-counter acetaminophen -- the key ingredient in Tylenol, Excedrin and many other pain-k...
FDA Advisers Recommend Smaller Doses of Acetaminophen
The drug can cause liver damage if used improperly
TUESDAY, June 30 (HealthDay News) -- FDA advisers voted Tuesday to recommend that the maximum dose for Tylenol and other pain medications should be reduced to help curb deadly overdoses.
The advisers recommended lowering the maximum...
Obese Get Higher Doses of Radiation for X-Rays
Cumulative effect of that needs study, experts say,,
TUESDAY, June 30 (HealthDay News) -- People who are overweight and obese are usually given higher-than-normal
doses of radiation in order to obtain usable X-ray images, even though the long-term effects are unknown, new research cont...
Study finds reproductive health effects from low doses of bisphenol-A
New research from North Carolina State University and the National Institute of Environmental Health Sciences (NIEHS) shows significant reproductive health effects in rats that have been exposed to bisphenol-A (BPA) at levels equivalent to or below the dose that has been thought not to produce any...
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doses in Medical Technology
Longevity Seekers Advised to Consume Modest Doses of Red Wine Molecules in Dietary Supplements (Longevinex(R)) Rather than Mega-Dose Resveratrol Alone
SAN DIMAS, Calif., Dec. 27 /PRNewswire/ -- According to the latest
science, resveratrol pill users are best advised to consume modest
doses of
resveratrol plus an array of antioxidant molecules as typically provided in 3
to 5 glasses of aged, red wine, rather than resveratrol alone.
(Ph...
CVBT Doses First Patient in its Phase II Clinical Trial for Severe Coronary Heart Disease
LAS VEGAS, Nov. 25 /PRNewswire-FirstCall/ -- CardioVascular
BioTherapeutics, Inc. (OTC Bulletin Board: CVBT), announced today that it has
dosed the first patient in North America (NA) as part of its ACORD Phase II
clinical trial to treat patients with severe coronary heart disease. The ACORD
(Angi...
Trius Doses First Patient in Antibacterial Phase 2 Trial
TR-701 Tested for Efficacy in Drug Resistant Skin Infections
SAN DIEGO, Sept. 22 /PRNewswire/ -- Trius Therapeutics, Inc. today
announced the initiation of Phase 2 testing of the oral form of its
second-generation oxazolidinone antibacterial drug TR-701. The multicenter
trial will test the e...
Peregrine Pharmaceuticals Doses First Patient in Phase II Trial of Bavituximab in Patients With Advanced Breast Cancer
- Peregrine Achieves Milestone as Third Phase II Trial in Its Bavituximab Cancer Program Begins Patient Enrollment and Dosing -
TUSTIN, Calif., Aug. 11 /PRNewswire-FirstCall/ -- Peregrine
Pharmaceuticals, Inc. (Nasdaq: PPHM ) today announced that patient screening
and dosing has begun ...
Sanofi Pasteur Shipping First Doses of Influenza Vaccine for the 2008-2009 Season in the US
SWIFTWATER, Pa. and LYON, France, Aug. 1 /PRNewswire/ -- Sanofi
Pasteur, the vaccines division of sanofi-aventis Group, began shipping
influenza vaccine (Fluzone(R), Influenza Virus Vaccine) in the United
States for the 2008-2009 season. The first 1.3 million
doses of influenza
vaccine began s...
Video: Resveratrol-based Nutriceutical (Longevinex(R)) Induces Favorable Changes on Gene Expression in Mouse Heart At Doses 17-320 Times Lower Than Prior Studies
Nutriceutical Shown To Affect 9-Fold More Longevity Genes Than Resveratrol Or A Limited-Calorie Diet Alone - Independent Laboratory Animal Study
SAN DIMAS, Calif., July 30 /PRNewswire/ -- Researchers report that a
proprietary nutriceutical matrix (Longevinex(R...
doses in Medical Products
HumaPen® MEMOIR Insulin Pen with Memory
Description:... HumaPen MEMOIR is the first and only insulin pen with a memory. HumaPen MEMOIR records the date, time, and amount of your last 16
doses (including priming doses). You can see exactly when and how much insulin you last took. With HumaPen MEMOIR, you simply "dial" your dose by turning th...
Company:Eli Lilly and Company
OmniPod Insulin Management System
Description:...nsulin pod that you fill with insulin and wear directly on your body for up to three days and then replace. The OmniPod delivers precise, personalized
doses of insulin into your body through a small flexible tube (called a cannula) based on instructions that you program into its wireless companion, the Per...
Company:Insulet Corporation
Simplex™ P Bone Cement
Description:...trade;. Simplex™ is the only cement with 40 years of proven clinical performance - trusted by tens of thousands of surgeons with over 15 million
doses implanted....
Company:Stryker Corporation
Cem-Ostetic Optimal Bone Generation
Description:...que putty formula sets up quickly with marginal exothermic reaction (less than 4C). The putty hardens within 5 minutes. Cem-Ostetic putty is available
doses ranging from 5cc to 30cc.
Cem-Ostetic is very easy to prepare in the surgery room, as illustrated to the right. Mix the powder in the vial with...
Company:Berkeley Advanced Biomaterials
Bi-Ostetic Slow Resorbtion Bone Filler
Description:...erconnected porosity resemble cancellous bone chips. The structure enhances osteo-conduction and ensures complete bone in-growth. Bi-Ostetic ranges in
doses from 1cc to 60cc....
Company:Berkeley Advanced Biomaterials
Isovue (iopamidol injection)
Description:...jection) is a safe and effective nonionic contrast medium well established with U.S. clinical experience since 1986. Worldwide, more than 250 million
doses of iopamidol have been administered. Indicated for a wide variety of radiological procedures, Isovue offers desired flexibility by providing a wide r...
Company:Bracco Diagnostics, Inc.
doses in Medical Definition
Allopathic medicine
...disease when given to a healthy human. Hahnemann used this term to distinguish medicine as practiced in his time from his use of infinitesimally small
doses of substances to treat the spiritual causes of illness.
In the essay by William Jarvis cited below, he notes that "although many modern therapies ca...
Full-body scan
... outweighed by the benefit of identifying a treatable disease at an early stage. [5] One of the risks of a full body CT scan is the relatively high
doses of radiation. [6] Conventional CT scanners may expose patients to 10 mSv of radiation, or over a hundred times that of a chest x-ray. [7] Howe...
Nuclear medicine
...umed that any radiation dose, however small, presents a risk. The radiation
doses delivered to a patient in a nuclear medicine investigation present a very s...stribution in the body and its rate of clearance from the body.
Effective
doses can range from 6 μSv (0.006 mSv) for a 3 MBq chromium -51 EDTA measurement...
doses in Medical Dictionary
Vitamin C
...y ... A non-profit corporation promoting scientific research on vitamin C . Includes news, summaries, books, articles, and links. ... with High
doses of Vitamin C ... Vitamin Express offers high-quality health supplements at ... Buffered Vitamin C 500mg. Country Life. 100 Tabs $9.60. ...
Vitamin D
...l ... Describes the "sunshine vitamin ." Includes function and negative results from both deficiency and large doses. Vitamin D3: Higher
doses Reduce Risk of Common Health Concerns. By ... Optimal Vitamin D status for colorectal cancer prevention: a quantitative meta analysis. ... K...
Tic douloureux
...ic douloureux Information. Find Free Reference & Encyclopedia Articles Quickly. ... But for tic , there is a good medical treatment--daily
doses of an antiepileptic ... treatments for tic douloureux are a ... Tic douloureux isn't rare. ... Tic douloureux is a painful, paroxysmal...
PTH
...H is made by the parathyroid glands, which are four pea-sized glands that lie ... One can laboratory test your PTH levels. ... Sometimes high
doses of calcium-magnesium are needed to help control PTH levels. ... Pth is a very portable POSIX/ANSI-C based library for Unix platforms which ......
Progesterone
...has the opposite effect by inhibiting myometrium ... Progesterone declines towards the time of delivery, leaving estrogen to increase ... High
doses of progesterone would be expected to impair fertility. ... Patients should be warned that progesterone might cause transient dizziness or ... ...
Polio immunization
... immunization ... Full immunization will reduce an individual's risk of developing polio . ... high infant immunization coverage with four
doses of oral polio vaccine in the ... ... offered by the polio vaccine, regardless of previous immunization status. Further polio immunizati...
doses in Biological News
Adding high doses of sludge to neutralize soil acidity not advisable
This release is available in Spanish .
Sludge obtained from water purification plants can be reused, as fertiliser for soils, for example or to reduce their acidity. The main aim of this University of the Basque Country (UPV/EHU) PhD research thesis was to study the effects of the applica...
Mixing large doses of both acetaminophen painkiller and caffeine may increase risk of liver damage
WASHINGTON, Sept. 26 2007 -- Consuming large amounts of caffeine while taking acetaminophen, one of the most widely used painkillers in the United States, could potentially cause liver damage, according to a preliminary laboratory study reported in the Oct. 15 print issue of ACS Chemical Research ...
New insights into health and environmental effects of carbon nanoparticles
...e. The transfer involved very low levels of nanoparticles, which did not have adverse effects on the fruit flies. Since larvae can tolerate very high
doses of nanoparticles in the diet, but adult flies show very different sensitivities, the environmental impact depends on the ecological context of nanopar...
Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth
...rly four weeks and suppressed tumor growth more effectively, and with minimal non-specific cytotoxicity, than in mice treated with clinically relevant
doses of cisplatin and paclitaxel.
Edward Sausville, M.D., Ph.D., an associate editor of Cancer Research and associate director for clinical research at ...
Chasing tiny vehicles
...rticles along their route, especially into living tumor cells. It is a prerequisite, though, for therapeutic approval and the definition of functional
doses to know the exact path of these carriers and the efficiency of their transport and uptake by cancer cells.
So far, only the appearance or absence ...
Plastics chemical retards growth, function of adult reproductive cells
... is the first to show that chronic exposure to low
doses of BPA can impair the growth and function of adult...ogesterone and 95 percent less testosterone. Lower
doses of BPA had a less dramatic but still considerable...dies that showed effects in animals exposed to low
doses of BPA led it to have "some concern for effects on...
doses in Biological Technology
Raptor Pharmaceuticals Doses First Patient in Phase 2b Clinical Trial of DR Cysteamine for Cystinosis
NOVATO, Calif., June 1 /PRNewswire-FirstCall/ -- Raptor Pharmaceuticals Corp. ("Raptor" or the "Company") (OTC Bulletin Board: RPTP), today announced that it has dosed the first patient in its Phase 2b clinical trial, conducted in collaboration with the University of California, San Diego ("UCSD...
Sanofi Pasteur Shipping First Doses of Influenza Vaccine for the 2008-2009 Season
SWIFTWATER, Pa. and LYON, France, Aug. 1 /PRNewswire/ -- Sanofi
Pasteur, the vaccines division of sanofi-aventis Group, began shipping
influenza vaccine (Fluzone(R), Influenza Virus Vaccine) in the United
States for the 2008-2009 season. The first 1.3 million
doses of influenza
vaccine began s...
Peregrine Pharmaceuticals Doses First Patient in Phase II Clinical Trial of Bavituximab in Patients With Advanced Breast Cancer
TUSTIN, Calif., Feb. 12 /PRNewswire-FirstCall/ -- Peregrine
Pharmaceuticals, Inc. (Nasdaq: PPHM ), a clinical stage biopharmaceutical
company developing targeted therapies for the treatment of cancer and
hepatitis C virus infection (HCV), today announced that patient dosing has
begun in its c...
InterMune Reports Second Quarter 2009 Financial Results and Business Highlights
...infected patients. Ritonavir is an antiviral compound commonly used at low
doses to enhance or "boost" the pharmacokinetic (PK) profiles of several marketed...include twice-daily dosing of ITMN-191 and significantly higher total daily
doses (600mg and 900mg twice daily) than those explored in the first four patient...
OncoGenex Reports Second Quarter 2009 Financial Results
...09 showed that OGX-427 was well
tolerated as a monotherapy. In addition, OGX-427 demonstrated declines
in circulating tumor cells at all
doses evaluated as well as evidence
of reduction in tumor markers. Reductions in circulating tumor cells
and tumor markers both suggest single...
Rib-X Pharmaceuticals Reports Positive Phase 2 Study Results for Radezolid in Community-Acquired Pneumonia
...acy of radezolid in the treatment of adult patients with mild to moderate community-acquired pneumonia (CAP). The study assessed the efficacy of three
doses of radezolid, administered either once or twice a day for seven to 10 days. It also evaluated the safety and tolerability of the three doses. The stud...
doses in Biological Products
Magnetofection - SilenceMag from OZ Biosciences
Description:... to use, SilenceMag is serum compatible and non toxic. Specifically designed for siRNA delivery, SilenceMag allows studying gene silencing at very low
doses of siRNA.
SilenceMag formulation gives reliable high gene silencing efficiencies in numerous cell types (primary cells, hard to transfect & cell lines...
Company:OZ Biosciences
Magnetofection - SilenceMag from OZ Biosciences
Description:... to use, SilenceMag is serum compatible and non toxic. Specifically designed for siRNA delivery, SilenceMag allows studying gene silencing at very low
doses of siRNA.
SilenceMag formulation gives reliable high gene silencing efficiencies in numerous cell types (primary cells, hard to transfect & cell lines...
Company:OZ Biosciences
Magnetofection - SilenceMag from OZ Biosciences
Description:... to use, SilenceMag is serum compatible and non toxic. Specifically designed for siRNA delivery, SilenceMag allows studying gene silencing at very low
doses of siRNA.
SilenceMag formulation gives reliable high gene silencing efficiencies in numerous cell types (primary cells, hard to transfect & cell lines...
Company:OZ Biosciences
DIGIVIEW from Kubtec
Description:...rom analog detectors. The large detector size further facilitates imaging of large specimens in short time periods, without exposing them to extended
doses of radiation....
Company:Kubtec
doses in Biological Definition
Alcohol
...medicinal, religious, and recreational reasons. While infrequent consumption of ethanol in small quantities may be harmless or even beneficial, larger
doses result in a state known as drunkenness or intoxication and, depending on the dose and regularity of use, can cause acute respiratory failure or deat...
Antibiotic
...nt failure, these practices can result in antibiotic resistance .
In the United States, a vast quantity of antibiotics is routinely included as low
doses in the diet of healthy farm animals, as this practice has been proved to make animals grow faster. Opponents of this practice, however, point out the ...
Barbiturate
... 10 percent of all sedative/hypnotic prescriptions in the United States are for barbiturates.
Other non-therapeutical use
Barbiturates in high
doses are used for physician-assisted suicide (PAS), and, in combination with a muscle relaxant , for euthanasia and for capital punishment by letha...
Colchicine
...a . Side-effects include gastro-intestinal upset and neutropenia . Starting the drug early during an attack of gout can exacerbate the symptoms. High
doses can also damage bone marrow and lead to anemia . It's not used in the treatment of cancer , as the dose required would lead to intolerable side-ef...
Gene therapy
...ndergo cell division. So the descendants of that cell will not have the extra gene. This means that treatment with the adenovirus will require regular
doses to add the missing gene every time new cells are produced without the gene.
Adeno-associated viruses
Adeno-associated viruses , from the parv...
Hepatitis B
...w routinely vaccinate infants against hepatitis B. In many areas, vaccination against hepatitis B is also required for all healthcare workers. Booster
doses are recommended every five to ten years for healthcare workers.
External links
NIH collection of links to relevant articles on Hepatitis ...
doses in Biological Dictionary
Vaccine
...the ... Vaccination is the administration of a vaccine to stimulate a protective immune ... of time that varies with the vaccine , the number of
doses required and ... To make a successful vaccine against a virus, the nature of these surface ... This vaccine comes in two forms. ... The vaccin...
Estrogen
...ment therapy ... Low-dose vaginal estrogen affects only the urinary ... with a uterus who take estrogen also need the hormone progestin ...
doses of estrogen . When to start. Limit progesterone. Effects on Bone Density ... The bone are stronger as long as estrogen is used. ... Estrogen ...