dose

Gene variations explain drug dose required to control seizures

Determining which variants of particular genes patients with epilepsy carry might enable doctors to better predict the dose of drugs necessary to control their seizures, suggest basic findings by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and the University College London. Patients often undergo a lengthy process of trial and error to find the dose of ant...

Second messenger NAADP shows fast, dose-related impact on satiety cycle

One traditional approach to pharmaceutical design uses so-called "first messengers" ?hormones, other natural facilitators or synthetic products ?to initiate various cellular cascades for the desired physiological effect. To date, despite concerted efforts at all levels of research, this approach has failed to develop a truly successful obesity drug to address this major global health problem....

High-dose flu vaccines appear to safely boost immunity in elderly

High-dose influenza vaccines may increase elderly patients' immune response without significant adverse effects, offering this vulnerable population additional protection against the flu, according to an article in the May 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. Vaccines containing inactivated influenza virus have been available for 50 years to prevent...

Sensors, a smart dose of medicine for cancer treatment

The INVORAD project developed systems for real-time radiation monitoring for patient dosimetry in Intensity Modulated Radiotherapy (IMRT). IMRT is a radiation therapy for cancers that improves clinical outcomes by more accurately targeting tumours and minimising the amount of radiation absorbed by healthy tissue. The result is that patients only receive a high radiation dose where they nee...

Hyena mothers give their cubs a helpful dose of hormones

Scientists have discovered that a dominant hyena puts her cubs on the road to success before they are born by passing on high levels of certain hormones that make her budding young leaders more aggressive and sexually advanced. The report, published in the April 27 issue of Nature, is the first study in mammals to demonstrate a relationship between a female's social rank and her ability to...

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Automated Dissolution of Prednisone with the MultiDose G3

Caliper Life Sciences Corporation, Applications Laboratory, Hopkinton, Massachusetts, USA Prednisone is commonly used in laboratories as a dissolution bath calibrator. Manual dissolution is a very time intensive process; hence automation of this technique is highly d...

dose at Medicine News

Pharmacies in for a dose of bitter medicine

In a long-delayed move, the Foods and Drugs Department is beginning to bare its fangs at chemists and druggists operating without qualified pharmacists, an offence under the Indian Drugs and Cosmetics Act, 1940. According to official sources, not only does this common practice jeopardise the health of the masses -- it allows untrained people to deal with high-risk drugs -- it also end...

Survival rates in breast cancer patients improved with "Dose Dense Chemotherapy"

A study conducted by the Cancer and Leukemia Group B (CALGB) and presented at the 25th Annual San Antonio Breast Cancer Symposium assessed the effectiveness of reducing the interval between successive doses of a commonly used chemotherapy regimen to improve survival rates in breast cancer// women. This study was conducted as follow-up of a mathematical model which was developed in the 198...

Low-dose Growth Hormone (GH) with diet and exercise may help weight loss

Growth Hormone (GH) replacement therapy dosed to normalize IGF-I levels may be an effective adjunct to lifestyle modification in a "clinically necessary" weight loss program for obese adults. The goal of all weight loss programs is to lose body fat but retain lean body mass such as muscle,but what happens is that when people go on a diet, after a while, they stop losing weight. Low level...

Low-Dose Hormones Help the Bones

Osteoporosis is a major cause of disability in older women. Estrogen therapy is often prescribed to prevent osteoporosis. However, many women are reluctant// to take hormone therapy because of the increased risk of breast cancer, heart disease, stroke and deep vein blood clots. Now, new research finds a lower dosage of estrogen increases bone density in women without possibly causing the...

The Link Between High-dose Steroid Use And Heart Disease Questioned

Patients who take high doses of steroids are more than twice as likely to have cardiovascular complications than patients who do not, say researchers based on findings of a recent study. Steroids are widely used // to treat inflammatory conditions of the skin, lungs, joints, digestive tract, such as asthma, inflammatory bowel disease, and some types of arthritis. The health records of 6...

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High Dose Rate (HDR) Treatment System

Description:This cutting edge High Dose Rate (HDR) treatment system includes the HDR 100 Template and HDR 200 Sandwich. Using the Template, simply load needles through the Sandwich. Then detach the Template, suture the Sandwich to the patient, and lock the Sandwich to secure the needles in place for the duration of the treatment fractions....
Company:North American Scientific

TherMatrx® Dose Optimized Thermotherapy™

Description:TherMatrx® Dose Optimized Thermotherapy™ is an advanced transurethral microwave thermotherapy system designed for in-office treatment of benign prostate hyperplasia (BPH). TherMatrx is the most widely used in-office BPH thermotherapy treatment in the United States. Unlike surgical solutions for BPH, TherMatrx does not require cutting, heavy sedation or hospitalization. A single TherMatr...
Company:AMS

D-xylose (Adult-25 g dose)

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

D-xylose (Adult-5 g dose)

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Methadose & Metabolite Confirmation/Quantitation, Serum or Plasma

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

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dose at Medicine Technology

Labopharm to Present Poster on Dose Titration of Once-daily Tramadol at 3rd International Forum on Pain Medicine

- Article Discussing Pharmacokinetics and Dose Proportionality ofCompany's Once-Daily Tramadol to be Published in BiopharmaceuticsJournal - LAVAL, QC, June 29, 2007 /PRNewswire-FirstCall/ - Labopharm Inc.today announced that it will present a poster discussing the dosetitration of its once-daily formulation of tramadol at the 3rdInternational Forum on Pain Medicine to be held June 28 to J...

Columbia Laboratories Reports Positive Results from Multi-dose Pharmacokinetic Study of Vaginally-administered Lidocaine

LIVINGSTON, N.J.--(BUSINESS WIRE)--Jun 27, 2007 - ColumbiaLaboratories, Inc. (NASDAQ: CBRX) today announced positive resultsfrom a recently-completed multi-dose pharmacokinetic study ofvaginally-administered lidocaine, which the Company is developingto prevent and treat dysmenorrhea. This 42-subject study was designed to provide data on bloodlevels associated with the Company's bioadhesiv...

Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone

Interim results in a randomized phase II/III clinical trialanticipated later this year SEATTLE, June 26, 2007 /PRNewswire-FirstCall/ -- CellTherapeutics, Inc. (CTI) announced the publication of preclinicalstudies, which demonstrate that treatment with pixantrone (BBR2778) resulted in minimal or no significant cardiotoxicity, whiledoxorubicin and mitoxantrone induced significant cardiac da...

Affymax Reports Phase 2 Clinical Dose Ranging Results of Once-Per-Month Hematide for the Treatment of Anemia

PALO ALTO, Calif.--(BUSINESS WIRE)--Jun 25, 2007 - Affymax, Inc.(Nasdaq:AFFY) today announced that additional Phase 2 clinicaltrial results for Hematide(TM) were presented at the European RenalAssociation-EDTA Congress being held in Barcelona, Spain by Iain C.Macdougall, M.D., a Hematide investigator from Kings College,London. Dr. Macdougall's poster included data in previously-treateddialy...

CytRx Announces Clinical Results from Its Rising Multiple Dose Trial with Arimoclomol for ALS

LOS ANGELES--(BUSINESS WIRE)--Jun 25, 2007 - CytRx Corporation(NASDAQ:CYTR), a biopharmaceutical company engaged in thedevelopment and commercialization of human therapeutics, todayreported safety and tolerability results from its previouslyannounced double-blind, placebo-controlled, rising multiple doseclinical trial in healthy volunteers with its drug candidatearimoclomol. CytRx believes...

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Dose concentration

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