Molecule tracking reveals mechanism of chromosome separation in dividing cells
University of Washington (UW) researchers are helping to write the operating manual for the nano-scale machine that separates chromosomes before cell division. The apparatus is called a spindle because it looks like a tiny wool-spinner with thin strands of microtubules or spindle fibers sticking o...
New telomere discovery could help explain why cancer cells never stop dividing
Lausanne, Switzerland, October 4, 2007 A group working at the Swiss Institute for Experimental Cancer Research (ISREC) in collaboration with the University of Pavia has discovered that telomeres, the repeated DNA-protein complexes at the end of chromosomes that progressively shorten every time a ...
AMN Healthcare Announces Second Quarter 2009 Results
...egment divided by average travelers on
assignment, divided by the number of days in the period presented.
(5) Days filled is calculated by
dividing the locum tenens hours filled
during the period by 8 hours. Revenue per day filled and gross profit
per day filled represent revenue a...
MedCath Corporation Reports Third Quarter Earnings
...e. We computed adjusted patient days by
dividing gross patient revenue by gross inpatient revenue a... our hospitals.
( j ) We computed occupancy by
dividing patient days by the number of
days in the period and then
dividing the quotient by the number
of staffed an...
United Therapeutics Corporation Reports Second Quarter 2009 Financial Results
...sted for the retrospective adoption of FSP APB 14-1.
(2) Calculated by
dividing earnings before non-cash charges presented
above by the weighted av...number of shares outstanding for the
period.
(3) Calculated by
dividing earnings before non-cash charges presented
above by the weighted av...
Scientists Test New Way to Get Drugs to Cancer Cells
...ive metastatic breast cancer.
"This treatment is much less toxic than chemotherapy because it is targeted to tumor cells rather than to all rapidly
dividing cells," Sgouros said. "Nanoparticles designed to deliver these powerful isotopes have a great potential in cancer therapy, particularly for metastatic...
Dividing in Medical Technology
Injection Reverses Heart-Attack Damage
...nto animals after a heart attack.
After birth, heart-muscle cells (cardiomyocytes) normally withdraw from the cell cycle - meaning they stop
dividing and proliferating. But the researchers, led by Bernhard Kuhn, M.D., and Kevin Bersell of the Department of Cardiology at Children's, were able to rest...
National Cancer Institute Research Identifies Unique Mechanism of Brostallicin's Anti-Tumor Effectiveness
...ects of brostallicin are enhanced by high tumor glutathione levels, a hallmark of drug-resistant tumors. Brostallicin was shown to affect DNA in both
dividing and quiescent cells. Its actions can be followed by induction of a specific DNA binding protein foci that can be detected in circulating blood cells. ...
Nemours Center for Childhood Cancer Research Team at the Alfred I. duPont Hospital for Children Identifies the Function of a Biomarker Present in Prostate Cancer Cells: New Insight into Therapeutic Benefit for Patients with Advanced Prostate Cancer
...ortant causative role in prostate cancer progression."
This study was initiated when the researchers found that PSMA was
present at the poles of the
dividing cells. These poles are complex
structures at the opposite ends of the cells that control the separation of
chromosomes equally into daughter cells dur...
St. Jude Finds Signaling System That Halts the Growth of a Childhood Brain Cancer
...ls,"
Roussel said.
In cell culture experiments, her group found that BMPs rapidly cause
the degradation of a protein called Math1, which occurs in
dividing GNPs,
but not in non-proliferating neurons. Twelve hours after BMP treatment,
researchers could detect no Math1 and cell growth soon stopped.
The ...
Pharmion Submits European Marketing Authorization Application (MAA) for Vidaza(R) in Patients with Higher-Risk Myelodysplastic Syndromes (MDS)
...y restore normal function to genes that
are critical for differentiation and proliferation. The cytotoxic effects
of Vidaza cause the death of rapidly
dividing cells, including cancer cells
that are no longer responsive to normal growth control mechanisms. Non-
proliferating cells are relatively insensitive t...
Pharmion and MethylGene Start Phase 2 Combination Clinical Trial With MGCD0103 and Vidaza(R) in Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma
...y restore normal function to genes that
are critical for differentiation and proliferation. The cytotoxic effects
of Vidaza cause the death of rapidly
dividing cells, including cancer cells
that are no longer responsive to normal growth control mechanisms. Non-
proliferating cells are relatively insensitive t...
Dividing in Medical Products
Alio-Prats Irrigating "Stinger"
Description:...ficient division of hard and soft nuclei. It features a bullet-shaped head for easy insertion through a micro incision and a short, "stinger" tip for
dividing and chopping the nucleus. In addition, the tip is ideal for retrieving fragments from underneath the iris which can be located peripherally inside th...
Company:Katena Products, Inc.
Model 4420 Colloid Osmometer
Description:...eter. Rapid measurement of colloid osmotic (oncotic) pressure for the prediction of edema onset in clinical situations. Uses a semi-permeable membrane
dividing sample and reference chambers to simulate the role of the natural vascular membrane in the establishment of osmotic pressure responsible for water flo...
Company:Wescor, Inc.
LDS™ (Single Use Loading Units with Stainless Steel Staples)
Description:...able loading unit.
The Auto Suture™ LDS-2™ instrument has application in abdominal, gynecological and thoracic surgery for ligating and
dividing blood vessels and other tubular structures....
Company:Autosuture
LDS™ (Powered Single Use Stapler with Titanium Staples)
Description:...abdominal, gynecological, orthopedic, and thoracic surgery for ligating and
dividing blood vessels and other tubular structures.
The Auto Suture™ Power...abdominal, gynecological, orthopedic, and thoracic surgery for ligating and
dividing blood vessels and other tubular structures....
Company:Autosuture
LDS-2™ (Reusable Instrument)
Description:...able loading unit.
The Auto Suture™ LDS-2™ instrument has application in abdominal, gynecological and thoracic surgery for ligating and
dividing blood vessels and other tubular structures....
Company:Autosuture
ENDOPATH ETS Compact-Flex45 Articulating Linear Cutters
Description:...
The ENDOPATH ETS Compact-Flex45 Linear Cutter is designed to deliver a 45mm staple and cut line for open surgical procedures, while simultaneously
dividing the tissue between the rows. It is available with either a standard blue cartridge, a thick-tissue green cartridge, or vascular thin-tissue white cart...
Company:Ethicon, Inc.
Dividing in Medical Dictionary
Nose fracture
...ver the bridge, in the sidewall, or septum (line
dividing the nostrils) of the nose . A nose fractur...ver the bridge, in the sidewall, or septum (line
dividing the nostrils) of the nose . Nose fracture ...ver the bridge, in the sidewall, or septum (line
dividing the nostrils) of the ... Nose fracture Chr...
Medial
...r example, the chest is medial to the arm. ... Information about medial in the free online English dictionary and encyclopedia. ... medial -
dividing an animal into right and left halves. median ... in length, situated behind the medial palpebral ligament and lacrimal sac (Fig. 379) .....
Atrial septal defect
...rial septal defect in childhood can prevent serious problems later ... An atrial septal defect is an opening in the atrial septum, or
dividing wall between the two upper chambers of the heart known as the right and left atria. Find treatment for atrial septal defect (ASD) an...
Dividing in Biological News
Spontaneous assembly
...erstand how these clusters form, what controls their size and density, and how the cellular location of clusters is robustly maintained in growing and
dividing cells."
Using PALM, Liphardt and his colleagues mapped the cellular locations of three proteins central to the chemotaxis signaling network - Tar, ...
Hormone clue to root growth
...the endodermis (the innermost layer of the root cortex of a plant), was sufficient to stop the meristem enlarging. In effect, the rate of expansion of
dividing endodermal cells dictates the equivalent rate in other tissues.
This research was headed by Dr Susana Ubeda-Toms and Professor Malcolm Bennett of t...
Female human embryos adjust the balance of X chromosomes before implantation
...o implantation when the X chromosome inherited from the father is turned off, while the maternal X chromosome remains turned on. As the cells carry on
dividing and reach the blastocyst stage, the cells that will go on to form the placenta continue to have the paternal X chromosome switched off, but it is swit...
DNA template could explain evolutionary shifts
...s, but it also demonstrates that copy number variation can occur at a different time in the life of a cell. DNA replication takes place as the cell is
dividing and becoming two a process known as mitosis.
Copy number variation involves structural changes in the human genome that result in the deletion of ...
UCLA cancer researchers develop model that may help identify cancer stem cells
...of cells in a tumor are cancer stem cells, making them hard to find and even more difficult to target. Current cancer therapies are designed to target
dividing cells, and the treatments do kill the majority of the cancer cells. But cancer stem cells can lay dormant and survive chemotherapy as well as the mole...
Is this the beginning of the end of plant breeding?
...
The first steps of both meiosis and mitosis are the replication of the
dividing cell's DNA. Once replication has occurred, the chromosomes condense into ti...netically identical daughter cells. In meiosis, there are two lining up and
dividing phases. The first lining up is of homologous chromosomesall chromosomes in ...
Dividing in Biological Technology
Novavax Announces Repayment of $5 Million of Convertible Debt
... payment of approximately $2.6 million and issued common stock for the remaining $2.6 million of the principal plus accrued and unpaid interest due by
dividing that principal amount by $2.5163, resulting in 1,016,939 shares of common stock.
"The repayment of the final portion of these convertible n...
Cell Therapeutics to Exchange up to $89.2 million of Its Outstanding Convertible Notes in a 'Modified Dutch Auction' Tender Offer
...s as part of the Exchange Consideration will equal the quotient obtained by
dividing (x) the Common Stock Portion by (y) the average of the daily volume weighte..., will be exchanged for that number of shares of Common Stock determined by
dividing (1) the amount of accrued and unpaid interest on a Note, by (2) the 10-day ...
Sanofi-aventis U.S. to Acquire Oral Chronic Lymphocytic Leukemia Treatment
...art of this transaction, sanofi-aventis U.S. will acquire these agreements.
Oforta is a nucleoside analogue designed to prevent cancer cells from
dividing by inhibiting DNA synthesis. Oforta was granted accelerated review and later received approval from the U.S. Food and Drug Administration (FDA) in De...
United Therapeutics Reports First Quarter 2009 Financial Results
... $1.36 $1.07
(1) Adjusted for the retrospective adoption of FSP APB 14-1.
(2) Calculated by
dividing earnings before non-cash charges by the
weighted average number of common shares outstanding, as reported
below in our Consolidated ...
Novavax Announces Early Retirement of $17 Million of Convertible Debt
... pay 70% of the principal plus accrued and unpaid interest in cash and will issue shares of its common stock for the remaining 30% of the principal by
dividing that principal amount by $2.50 for a total payment of approximately $12 million in cash and 2,040,000 shares of common stock. The remaining $5 millio...
Medco Delivers First-Quarter 2009 GAAP Diluted EPS of $0.58; Diluted EPS Excluding Amortization of Intangible Assets of $0.63; Reaffirms 2009 EPS Guidance; Announces Win of Coventry Commercial Business Starting January 1, 2010
...lculation of EBITDA may not be consistent with calculations of EBITDA used by other companies.
EBITDA per adjusted prescription is calculated by
dividing EBITDA by the adjusted prescription volume for the period. This measure is used as an indicator of EBITDA performance on a per-unit basis, providing ...
Dividing in Biological Products
Dividing in Biological Definition
Apoptosis
... blocked (by a virus), a damaged cell can continue
dividing without restrictions, developing into cancer . Fo...d, either of two things happen:
The cells are
dividing faster than they die, effectively developing a tumor .
The cells are
dividing slower than they die, which results in a disorder ...
Cancer
...es . Most forms of chemotherapy target all rapidly
dividing cells and are not specific for cancer cells. Hence...ence ), then it ceases to divide. Tumor cells keep
dividing forever.
Altered morphology .
Building of c...ng the distinguishing traits are a large number of
dividing cells, variation in nuclear size and shape, vari...
Cell division
...ss of a biological cell (called a mother cell )
dividing into two daughter cells . This leads to growth in...rate and die, causing the body to age. Cells stop
dividing because the telomeres , protective bits of DNA on...nzyme called telomerase allows them to continue
dividing indefinitely.
See also
Cell cycle
C...
Chromosome walking
...DNA strand, e.g., a chromosome . As the traditional chain termination method does not allow long DNA strands to be sequenced, this method works by
dividing the long sequence into several consecutive short ones.
The basic technique is as follows:
A primer that matches the beginning of the DNA to ...
Cladistics
...t all taxa are inherently subjective, even when they reflect evolutionary relationships, since living things form an essentially continuous tree. Any
dividing line is artificial, and creates both a monophyletic section above and a paraphyletic section below. Paraphyletic taxa are necessary for classifying e...
Cytoskeleton
...al for recruiting other proteins that produce a new cell wall between the
dividing cells.
MreB and ParM
Prokaryotic actin-like proteins, such as MreB ...f ParM exhibit dynamic instability , and may partition plasmid DNA into the
dividing daughter cells by a mechanism analogous to that used by microtubules duri...
Dividing in Biological Dictionary
Telomere
...... New Telomere Discovery Could Help Explain Why Cancer Cells Never Stop
dividing ... Research into telomere maintenance is at the forefront of the biom...... New Telomere Discovery Could Help Explain Why Cancer Cells Never Stop
dividing ... Encyclopedia article of Telomere at Reference.com compiled from co...
Spermatogonia
...rmatogonia are about 50% lower than in the normal ... We confirm that Apale spermatogonia divide equally at stage VII and produce two ... Rarely
dividing single A spermatogonia exist which potentially are the male ... ... seminiferous tubules consist of diploid spermatogonia , stem cells t...
Skin cell
...severe burns. Skin Cell Types. Keratinocytes. The most abundant cell type of the epidermis is the keratinocyte. ... properly in the skin ,
dividing cells are protected from ... A four-minute short exploring identity and the process of self-reflection entirely constructed through the manipul...
Secondary palate
...ate : as mentioned above, several very different lineages, ... This species is well on its way to developing a full secondary palate . ... The
dividing point of the primary and secondary palate is the incisive foramen. ... Submucous clefts of the secondary palate may also occur. ... ... the...
Root cap
...r this purpose the root cap is made up of layers of flattened and hardened cells. ... The cells of the root - cap are produced by the actively
dividing cells ... ...
Nuclear membrane
...( nuclear membrane ) ... iv, nuclear membrane . iii, site of ribosome assembly. i, division of preexisting mitochondria ... Just how a
dividing cell rebuilds the nuclear envelope, the protective, functional wrapping that encases both the original and newly copied genetic material, has ... ...