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disrupts in Medical News

Molecule Disrupts DNA Sequence in Ewing's Sarcoma

Finding could yield first targeted therapy for the rare disease, researchers say MONDAY, April 14 (HealthDay News) -- A molecule that disrupts the oncogene that causes Ewing's sarcoma has been identified by Georgetown University Medical Center researchers. Ewing's sarcoma is a rar...

Parkinson's Disrupts Stem Cell Therapy Transplants

Dopamine neurons may not work long-term, as disease causes pathologic changes in cells SUNDAY, April 6 (HealthDay News) -- Current therapies using stem cell transplants in the brains of patients with Parkinson's disease may not work long-term, because the disease is an ongoing process ...

How DDT metabolite disrupts breast cancer cells

Research has shown that the main metabolite of the insecticide DDT could be associated with aggressive breast cancer tumours, but there has been no explanation for this observation to date. Now a report published in the open access journal Breast Cancer Research shows how DDT could act to disrupt ...

Antibacterial chemical disrupts hormone activities

A new UC Davis study shows that a common antibacterial chemical added to bath soaps can alter hormonal activity in rats and in human cells in the laboratoryand does so by a previously unreported mechanism. The findings come as an increasing number of studies of both lab animals and humans are...

Nicotine in breast milk disrupts infants' sleep patterns

PHILADELPHIA (September 4, 2007) - - A study from the Monell Chemical Senses Center reports that nicotine in the breast milk of lactating mothers who smoke cigarettes disrupts their infants' sleep patterns. Infants spent less time sleeping overall and woke up from naps sooner when their mothers...

Ulcerative Colitis Disrupts Many Aspects of Daily Life: Survey

Nearly three out of four ulcerative colitis (UC) sufferers responding to a new nationwide survey say not feeling well has become a normal part of life . Furthermore, they describe UC as disruptive when it comes to their relationship with a spouse, their sexual relations and their emotional state. ...

Model of Internal Clocks Reveals How Jet Lag Disrupts the System

Symptoms of extreme jet lag may result from the body overshooting as it tries to adjust to particularly large leaps forward in time, suggests new research// from the University of Massachusetts Amherst that models circadian rhythms in rats. To transition smoothly to a different time zone, the resea...

A sty in Actress Konkona Sharma Disrupts the Shooting of Bi- Lingual movie 'Sunglass'

The Shooting of Director Rituparno Ghosh’s film “Sunglass” was unfortunately bought to a halt today in Mumbai. This was due to actress Konkona Sen Sharma’s right eye swelling// up forcing the production crew to pack up for the day. Apparently make up could not conceal the swollen area. But th...

American Health Assistance Foundation & Asbury Methodist Village to Host Special Community Screening and Discussion of the HBO Series, The Alzheimer's Project

... the relationship between a protein called presenilin and the brain's way of regulating calcium concentrations. Dr. Foskett has shown that presenilin disrupts the regulated calcium in cells causing a cascade of events including accumulation of free radicals, which can run amuck and ultimately lead to Alzheim...

Scientists Learn How Cancer Drugs Cause Hypertension

... University Medical Center in Durham, N.C., said in a school news release. "Our studies in mice show that blocking VEGF causes hypertension because it disrupts an important biological system -- the nitric oxide pathway that regulates blood vessel health." The researchers used an antibody to block an import...
disrupts in Medical Technology

In Rare Disorder, a Familiar Protein Disrupts Gene Function

-Knowledge May Improve Diagnosis for Children with Cornelia deLange Syndrome- PHILADELPHIA, May 27 /PRNewswire-USNewswire/ -- An international team of scientists studying a rare genetic disease discovered that a bundle of proteins with the long-established function of keeping chromo...

Pharmaxis Announces Positive Results of Phase 3 Cystic Fibrosis Trial

...onstant flow of mucus over the surfaces of the air passages in the lungs, removing debris and bacteria. In CF, an inherited disease, a defective gene disrupts ion transport across the epithelial membrane within cells. In the lungs, this leads to a depletion of the airway surface liquid that normally bathes ...

Patient Enrollment in Urgent(R) PC SUmiT Clinical Trial Completed Ahead of Schedule

...cy and urinary frequency, symptoms often associated with overactive bladder. Application of neuromodulation therapy targets specific nerve tissue and disrupts the signals that lead to these symptoms. Uroplasty sells the Urgent PC system in the United States, Canada, and countries recognizing the CE mark. O...

Alba Therapeutics Announces Enrollment of Its First European Patient in Global Phase IIb Study of Larazotide Acetate for Treatment of Active Celiac Disease

...zotide acetate inhibits tight junction opening triggered by both gluten and inflammatory cytokines, thus reducing uptake of gluten. Larazotide acetate disrupts the intestinal permeability-inflammation loop, and reduces symptoms associated with celiac disease. Larazotide acetate is orally formulated, has been ...

Topical Treatment for Cold Sores Achieves Efficacy of Oral Drugs; Represents Paradigm Shift in the Treatment of Skin Infections

...ate skin pores and hair follicles is essential to its activity in the dermis and epidermis, where it surrounds and fuses with herpes simplex virus and disrupts the outer envelope of the pathogen," Flack said. "NB-001 does not compromise tissue integrity, so it is not absorbed into the bloodstream." Because ...

Cytopia Commences Second Phase II Study in Brain Cancer

...en of the study's 31 advanced cancer patients. Significant perturbations in tumor blood flow were also demonstrated, suggesting that CYT997 potently disrupts tumor blood vessels. Findings from this study were recently presented at the American Society of Clinical Oncology Annual Meeting which attracts some ...

Uroplasty Highlights Clinical Results From a Study of the Urgent(R) PC Neuromodulation System

...ncy and urinary frequency, symptoms often associated with overactive bladder. Application of neuromodulation therapy targets specific nerve tissue and disrupts the signals that lead to these symptoms. Uroplasty sells the Urgent PC system in the United States, Canada, and countries recognizing the CE mark. Out...

UltraShape(R) Non-Invasive Fat Reduction and Body Contouring Clinical Study Results Featured at American Society for Laser Medicine and Surgery Meeting

... of patients worldwide. The UltraShape proprietary non-invasive body contouring technology is based on focused ultrasound that targets and selectively disrupts fat cells without affecting surrounding structures. Founded in 2000, UltraShape is a privately held and venture backed company with offices in the Uni...

Independent Clinical Results Confirm Up to a 7-Centimeter Reduction in Body Circumference Using UltraShape(TM) Non-Invasive Fat Reduction and Body Contouring System

... of patients worldwide. The UltraShape proprietary non-invasive body contouring technology is based on focused ultrasound that targets and selectively disrupts fat cells without affecting surrounding structures. Founded in 2000, UltraShape is a privately held and venture backed company. For more information v...

First Patient Dosed with KX2-391 in Phase 1 Clinical Trial

...naler called Src kinase, a protein linked to the rapid growth and spread of cancer cells. A potential advantage of Kinex's kinase inhibitor is that it disrupts Src at a site different from where other currently studied compounds are targeted, reducing the chance that patients will develop resistance to the ne...
disrupts in Medical Products

ACULAR® 5 mL

Description:... ACULAR® ophthalmic solution is a prescription eye drop that your doctor may instruct you to use after your cataract surgery. Cataract surgery disrupts the eyes and may cause them to become inflamed. The key signs and symptoms of inflammation include redness and swelling. If left untreated, inflammati...
Company:Allergan, Inc.

ACULAR® 10 mL

Description:... ACULAR® ophthalmic solution is a prescription eye drop that your doctor may instruct you to use after your cataract surgery. Cataract surgery disrupts the eyes and may cause them to become inflamed. The key signs and symptoms of inflammation include redness and swelling. If left untreated, inflammati...
Company:Allergan, Inc.

ACULAR® 3 mL

Description:... ACULAR® ophthalmic solution is a prescription eye drop that your doctor may instruct you to use after your cataract surgery. Cataract surgery disrupts the eyes and may cause them to become inflamed. The key signs and symptoms of inflammation include redness and swelling. If left untreated, inflammati...
Company:Allergan, Inc.
disrupts in Medical Dictionary

Spinal Cord Injuries

...ion of the spinal cord . ... is doctors are frequently confused about the definition of spinal cord injury ... A spinal cord injury disrupts the communication between the brain and other ... · Sports injuries – 8% Spinal cord damage can also occur from diseases such as ... There a...

Spinal Cord Injury

...habilitation 2000. 6(1):1-7. Northwest Regional Spinal Cord Injury System, University of Washington School of ... A spinal cord injury disrupts the communication between the brain and other ... An individual with a spinal cord injury may experience a loss of function, such ... There ...

Peripheral neuropathy

...ve with ... ... awareness and seeking a cure for CIDP, peripheral neuropathy and other nerve ... Peripheral neuropathy or "nerve damage" disrupts the body's ability to ... Peripheral neuropathy is a problem with the nerves that carry information to and ... Peripheral neuropathy may i...

Palpitations

...heart is beating forcefully, rapidly, or irregularly. ... Palpitations can be very frightening. ... Palpitations usually occur when something disrupts the normal electrical ... Sometimes, palpitations occur for unknown reasons in people with no evidence of ... Palpitations are heartbeat sens...

Neurologic deficit

...s a functional abnormality of a body area due to a ... A focal neurologic deficit is a problem in nerve, spinal cord, or brain function ... or disrupts any PART of the nervous system can cause a focal neurologic deficit . ... Neurologic deficit . Information: A neurologic deficit is a de...

Myelitis

... Myelitis is a disease involving inflammation of the spinal cord, which disrupts central nervous system functions linking the brain and limbs. Not-for-profit organization providing support to families affected by TM. Tran...

Diabetic foot

...putation Prevention(American College of Foot and ... Article: Current concepts review: diagnostic imaging of the diabetic foot . ... Diabetes disrupts the vascular system, affecting many areas of the body such as the eyes, kidneys, legs, and feet . ... Diabetic foot conditions develop from a ....

Binge eating

...h information on binge eating disorder including causes, symptoms, ... Treatments for Binge Eating : Know Your Options ... Binge eating disrupts the lives of 3.5% of U.S. women and 2% of U.S. men, for an average of eight ... you don't have binge eating disorder if you ... What are the h...

Appetite

...Found to Reduce Appetite , Caloric Intake at Meals ... Eating Too Much Fat disrupts Body's Internal Clock, disrupts Appetite Control ... A Young Couple Goes Out For Unch In Their First ...
disrupts in Biological News

Stress disrupts human thinking, but the brain can bounce back

A new neuroimaging study on stressed-out students suggests that male humans, like male rats, don't do their most agile thinking under stress. The findings, published this month in the Proceedings of the National Academy of Sciences , show that 20 male M.D. candidates in the middle of preparing fo...

In lung cancer, silencing one crucial gene disrupts normal functioning of genome

PHILADELPHIA While examining patterns of DNA modification in lung cancer, a team of international researchers has discovered what they say is a surprising new mechanism. They say that "silencing" of a single gene in lung cancer led to a general impairment in genome-wide changes in cells, contribu...

Scientists determine structure of enzyme that disrupts bacterial virulence

First step toward developing enzymes to treat diseases such as cystic fibrosis, reduce bacterial biowarfare threatsA team of biomedical researchers from Brandeis University and the University of Texas at Austin has determined the first 3-dimensional structure of an enzyme that may be pivotal in pre...

Alcohol consumption disrupts breastfeeding hormones

Despite age-old claims advising breastfeeding moms that alcoholic beverages can improve their nursing performance, researchers at the Monell Chemical Senses Center report that even moderate doses of alcohol affect the hormones responsible for lactation in a counterproductive manner. "This informa...

Holding breath for several minutes elevates marker for brain damage

...and may have cumulative effects," the Swedish researchers said. The release of S100B into the blood suggests that holding one's breath for a long time disrupts the blood-brain barrier, they said. The concern is that repetitive exposures to severe hypoxia (lowered oxygen supply), such as that experienced by...

Protein that promotes cancer cell growth identified

...se-8 associates with Src, a protein known to be involved in cancer cell proliferation. In this study they showed that interruption in this association disrupts EGF signaling indicating that Caspase-8 exerts EGF signaling through Src. Cancer results from excessive cell division and reduced cell death. A num...

Sticky protein helps reinforce fragile muscle membranes

...inical implications. The team showed that a virus called LCMV (Lymphocytic Choriomeningitis virus), which binds tightly to alpha dystroglycan, also disrupts the basal lamina muscle membrane interaction and compromises the integrity of the muscle membranes. LCMV is a member of a group of viruses that can ca...

New lab test offers better prediction of HIV microbicide safety

...icrobicide's safety. The cells of the vaginal epithelium normally are tightly packed together, forming an impermeable barrier to HIV. If a microbicide disrupts the barrier's structural integrity, HIV would be able to slip through the gaps and infect circulating T cells. To test this theory, Pedro Mesquita,...

Specific genetic cause of fetal alcohol-related developmental disorders found

...te alcohol consumption during pregnancy. The study, which was funded by the National Institutes of Health, demonstrated that fetal alcohol exposure disrupts the epigenetic "imprinting" of Dio3. In this process, Dio3 normally originates from the father's gene, while the maternal gene is silenced by epigenet...

UCSF discovers new glucose-regulating protein linked with diabetes

...e mouse capable of expressing CHC22 in its muscles and fat, which was analyzed in the study. These mice have features of diabetes, because the protein disrupts their GLUT4 transport pathway, which normally operates without CHC22. Also instrumental to the study was a human muscle cell line produced by the coll...
disrupts in Biological Technology

Discovery of a new retinal gene involved in childhood blindness

... cell mechanism at play Researchers have now identified a total of fifteen genes involved in LCA, but SPATA7 is the first gene with a mutation that disrupts the protein transport between two important compartments of the cell: the endoplasmic reticulum and the Golgi apparatus. All proteins in every cell ha...

Research Published in Nature Medicine Shows Disruption of Chemokine Interactions Inhibits Atherosclerosis in Mice

...ry structural motif found in RANTES when stabilized by disulfide bridged cysteines at both ends of the peptide. The scientists demonstrated that CKEY2 disrupts PF4-RANTES heteromer formation by binding preferentially to RANTES. In vitro assays demonstrated that CKEY2 inhibited the recruitment of monocytes t...

Cylene Pharmaceuticals Initiates Phase II Clinical Trial of Quarfloxin (CX-3543) in Patients With Carcinoid/Neuroendocrine Tumors

... neural crest cells. "Quarfloxin (CX-3543) is a small molecule that disrupts a protein:rDNA complex that forms in the abnormal nucleoli of cancer cells,...ctively inhibit ribosomal RNA (rRNA) biogenesis in cancer cells, quarfloxin disrupts the interaction between the Nucleolin protein and a G-quadruplex DNA struct...

Green Makeup Artist Paige Padgett Says, 'Get Smart'

...risk of certain ovarian cancers. C. Fragrance--this term is used to mask hundreds of chemical ingredients including phthalates which disrupts the endocrine system and may cause reproductive and developmental harm. 2) Plan ahead. Make shopping easier by checking online first for ...

Leading Heart Specialist Joins Duska Therapeutics as Scientific Consultant

...the heart to release calcium from intracellular stores. Calcium is the primary determinant of contractility in the heart. A deficiency in nitric oxide disrupts the calcium cycle, inhibits heart contractility, and ultimately causes the heart to fail. In addition to helping to elucidate a biologic basis of he...

UltraShape Appoints Assaf Eyal as President & CEO

... of patients worldwide. The UltraShape proprietary non-invasive body contouring technology is based on focused ultrasound that targets and selectively disrupts fat cells without affecting surrounding structures. Founded in 2000, UltraShape is a privately held and venture backed company. The UltraShape system ...

Not the protein, but its location in the cell, determines the onset of leukemia

...n of white blood cells is disturbed: the cells that should develop into white blood cells multiply out of control without fully maturing. This process disrupts the production of normal blood cells, making patients more susceptible to infections. T-ALL, a particular form of leukemia, is the most prevalent canc...

Cynosure Introduces Smartlipo MPX(TM) Dual Wavelength Workstation for LaserBodySculpting(SM)

... and skin tightening results. The two wavelengths can also be used individually and each offers unique characteristics. The 20 watt 1064-nm wavelength disrupts a broad region of tissue while heating the treated areas evenly. The 1064-nm wavelength also mediates blood vessel coagulation enhancing hemostasis. T...

JCI table of contents: April 22, 2008

... Stphane Prost and colleagues, at the Institute of Emerging Disease and Innovative Therapies, CEA, France, have now indicated that the HIV protein Nef disrupts the function of hematopoietic progenitor cells. In the study, production of the protein Nef was shown to be essential for the monkey form of HIV (S...

Nanoemulsion vaccines show increasing promise

...is the Ruth Dow Doan Professor of internal medicine and Allergy Division chief at the U-M Medical School. The surface tension of the nanoparticles disrupts membranes and destroys microbes but does not harm most human cells due to their location within body tissues. Nanoemulsion vaccines are highly effecti...
disrupts in Biological Definition

Patau syndrome

...creases as a woman gets older. People with Patau syndrome have additional DNA from chromosome 13 in some or all of their cells. The extra material disrupts the normal course of development, causing the characteristic features of Patau syndrome. Most cases of Patau syndrome result from trisomy 13, whi...

Pentose phosphate pathway

...4-phosphate → glyceraldehyde 3-phosphate + fructose 6-phosphate (transaldolase) See also G6PDH deficiency - A hereditary disease which disrupts the pentose phosphate pathway. NADPH RNA ...
disrupts in Biological Dictionary

Polysome

... Microarray Project - Web supplement to the paper from Diehn M. et al., submitted, 1999. ... Membrane-bound polysome data set ... Arsenite stress disrupts the polysome binding of PMR1 and its substrate mRNA but ... Preparation of cell extracts, polysome profile analysis, and glycerol gradients. ....

Peripheral protein

...elin protein 22 is produced primarily by specialized cells called ... The buildup of unprocessed peripheral myelin protein 22 probably also disrupts ... Schwann cells are part of the peripheral nervous system that connects the brain ... myelin peripheral protein . myelin protein z...

Pathogenic

..... Pathogenic organisms result from gene shuffling, which inadvertently disrupts ... Pathogenic organisms result from gene shuffling, which inadvertently disrupts ... Pathogenic viruses are only the tip of the iceberg' of virus types,...

Interference

...tation ... such experiments the interference pattern will be changed ... In communications, interference is anything which alters, modifies, or disrupts ... Interference is involved in Thomas Young's double-slit experiment where coherent ... Find out information about AM/FM radio interference an...
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(Date:4/23/2014)... Inverse Effects of Midlife Occupational and Leisure Time Physical ... occupational physical activity in midlife increases the risk of ... decreases the risk. This is found in a study ... years. The study was conducted at the Gerontology Research ... Health. , Heavy physical labor is often repetitive, wears ...
(Date:4/22/2014)... a popular high school sport in the United States ... by researchers in the Center for Injury Research and ... compare and describe the occurrence and distribution patterns of ... school athletic training setting among adolescents and teens. , ... Athletic Training , examined data relating to adolescents 13-19 ...
(Date:4/22/2014)... 2014 Researchers at UT Southwestern Medical Center are ... depression . , A team of physician-scientists at ... ghrelin (a hormone with natural anti-depressant properties) works inside ... new treatment for depression in the form of a ... study, published online in April,s issue of Molecular ...
(Date:4/22/2014)... mice and rabbits, Johns Hopkins scientists have found a ... successfully preventing the development of atherosclerosis, the main cause ... of death among humans. The condition develops when fat ... stiff, narrowed and hardened, greatly reducing their ability to ... brain. , In a series of experiments, described April ...
(Date:4/22/2014)... (SALT LAKE CITY)A computational tool developed at the University ... with unknown gene mutations in three separate cases, U ... new study in The American Journal of Human ... Re-ranking tool), identifies undiagnosed illnesses and unknown gene mutations ... proteins that code for genes are made, in individual ...
Breaking Medicine News(10 mins):Health News:Midlife occupational and leisure-time physical activity limits mobility in old age 2Health News:New study finds 2.5 million basketball injuries to high school athletes in 6 seasons 2Health News:New study finds 2.5 million basketball injuries to high school athletes in 6 seasons 3Health News:Depressed? Researchers identify new anti-depressant mechanisms, therapeutic approaches 2Health News:Depressed? Researchers identify new anti-depressant mechanisms, therapeutic approaches 3Health News:Scientists alter fat metabolism in animals to prevent most common type of heart disease 2Health News:Scientists alter fat metabolism in animals to prevent most common type of heart disease 3Health News:Scientists alter fat metabolism in animals to prevent most common type of heart disease 4Health News:Applying math to biology: Software identifies disease-causing mutations in undiagnosed illnesses 2Health News:Applying math to biology: Software identifies disease-causing mutations in undiagnosed illnesses 3
(Date:4/23/2014)... million Food Standards Agency (FSA) project to map the ... , Norovirus outbreaks can rapidly affect large numbers ... strawberries infected 11,000 people in Germany, but there are ... cause infection and which foods are the most likely ... produce data that will help the FSA to develop ...
(Date:4/22/2014)... Coral Gables, Fla. (April 21, 2014) -- There are ... out their feathers and spread their colorful tails; satin ... them with blue and shiny objects; and European bitterling ... Each species has evolved a unique method to communicate ... "Signaling can have profound fitness ...
(Date:4/22/2014)... FL, April 22, 2014 Scientists from the Florida ... a protein complex that plays a critical but previously ... The study, which showed a novel role for a ... in the journal eLife , a publisher supported ... Society and the Wellcome Trust. , "This is a ...
Breaking Biology News(10 mins):Best practices in communication for the animal world 2Best practices in communication for the animal world 3Scientists identify critical new protein complex involved in learning and memory 2
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