Discovery

Protein discovery could unlock the secret to better TB treatment

UCL scientists have found a protein that could unlock the secret to quicker, more effective treatment of TB by waking TB bacteria in the body. Once the TB bacteria are active again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way to designing drugs which enable treatment of dormant and...

Purdue proves concept of using nano-materials for drug discovery

Researchers at Purdue University have built and demonstrated a prototype for a new class of miniature devices to study synthetic cell membranes in an effort to speed the discovery of new drugs for a variety of diseases, including cancer. The researchers created a chip about one centimeter square that holds thousands of tiny vessels sitting on top of a material that contains numerous pores...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

Few things about growing older are asinevitable and obvious as “going gray,?yet scientists have been unableto explain the precise cause of this usually unwelcome transformation.In a report posted today on the Web site of the journal Science,researchers from Dana-Farber Cancer Institute and Children’s HospitalBoston say they have found the cellular cause of graying hair whileinvestigating th...

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

Scientists at St. Jude Children's ResearchHospital have discovered that the shape of a protein on the surface ofpneumonia bacteria helps these germs invade the human bloodstream. Thisfinding, published Dec. 16 online by the EMBO Journal, could helpscientists develop a vaccine that is significantly more effective atprotecting children against the disease. The St. Jude researchersdetermined t...

UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections

A team led by Johns Hopkins scientists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability to recognize and respond to a milliondifferent proteins might have originated from a family of genes whoseonly apparent function is to jump around in genetic material. essentially cut...

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Discovery at Biology Products

Imaging Mass Spectrometry for Small Molecule Localization from Protein Discovery, Inc.

Description:ions and aligns them with histological images so you can localize drugs and metabolites prior to synthesizing radiolabeled c...
Company:Protein Discovery, Inc.

Small Non-coding RNA Discovery Microarray - Comprehensive Service from LC Sciences

Description:LC Sciences provides a comprehensive microarray service for systematic discovery of small regulatory/functional RNA embedded within non-coding RNAs (ncRNAs) using a novel Paraflo technology and proprietary probe design, which enables highly sensitive and specific direct detection of small RNAs (1). This comprehensive service includes custom probe design (according to submitted target RNA sequence...
Company:LC Sciences

BD Falcon Roller Bottle, smooth surface from BD Biosciences - Discovery Labware

Description:BD Falcon 850 cm Smooth-surface TufRol Roller Bottle, tissue-culture treated polystyrene, blow-molded one-piece design, with easy on/off non-vented cap, packed in double bag. (20/ca) Packaging: 20 / double pack, 20 / case...
Company:BD Biosciences - Discovery Labware

BD Falcon Roller Bottle, smooth surface from BD Biosciences - Discovery Labware

Description:BD Falcon 850 cm Smooth-surface TufRol Roller Bottle, tissue-culture treated polystyrene, blow-molded one-piece design, with easy on/off non-vented cap. (2/sp, 20/ca) Packaging: 2 / pack, 20 / case...
Company:BD Biosciences - Discovery Labware

BD Falcon 1536-well Black/Clear Microplates from BD Biosciences - Discovery Labware

Description:BD Falcon microtest assay plate. 1536 well 12l, black BD Optilux PS. Polystyrene, nonsterile, no lid (15/sp, 60/ca)...
Company:BD Biosciences - Discovery Labware

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Discovery at Biology Technology

Medical College researchers receive new grants to enhance discovery of heart-protecting anesthetics

Zeljko Bosnjak, Ph.D., professor and vi...

UW discovery could lead to new TB treatments

MADISON -The family of bacteria that causes tuberculosis (TB) and leprosy are notoriously sturdy. And although the diseases they cause have been held in check for the past 50 years by antibiotics, some strains are becoming increasingly resistant to existing therapy. Now, however, a new chink has been found in the cellular armor that makes these infectious diseases difficult to treat. The...

SEESNP DISCOVERY

Agencourt offers a SNP discovery service for rapid and highly accurate identification of SNP loci. Our SeeSNP service is based on a targeted resequencing strategy and is fueled by our capacity to sequence over 20 million Phred20 bases a day. Features that set our service facility apart include:...

siRNA screening of the cell cycle with two dynamic GFP sensors (from Discovery Matters Issue 1, July 2005)

M. Kenrick, S. Hancock, S. Stubbs, and N. Thomas GE Healthcare, The Maynard Centre, Cardiff, UK Recent advances in siRNA methodologies and the development of high-throughput image analysis platforms such as the IN Cell Analyzer have revolutionized the functional analysis of genes and proteins. Here, we describe the application of...

Exploiting the Life Science Data Explosion to Speed New Drug Discovery

This paper discusses key problems and opportunities created by the explosion in both the degree (volume) and complexity of life science data available today, and presents a strategic and technological approach to data integration that enables r...

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Discovery at Medicine News

Discovery of bone gene

According to researchers- a gene mutation causing high bone density, which could open the way to new osteoporosis treatments. Bone is a dynamic material, which is being formed and destroyed all the time. When the bone loss side of the equation predominates, you are at risk of osteoporosis.// But researchers at Texas University have been studying a family with unusually high bone density - the opp...

Latest discovery on Autism

Scientists have ruled out a possible connection to autism. A study in this week's issue of British Medical Journal shows children with autism are no more likely than those without it to have had gastrointestinal problems as infants. // Study investigators from Boston University identified 90 children with autism and compared them to children without autism. They reviewed the children's...

Bacterial discovery may help CF patients

Microbiologists from Australian and Danish have discovered a way to prevent or disturb the formation of bacterial colonies, which they believe may bring a string of benefits from preventing lung infections in cystic fibrosis sufferers to cleaner contact lenses.// The discovery, by scientists at the University of Queensland's Institute for Molecular Bioscience and the Technical University of Denma...

A new discovery about Acetaminophen

According to a new enzyme which is discovered, may interpret the reasons for acetaminophen acting differently from other painkillers. //Acetaminophen (paracetamol in the UK) is known to relieve pain and fever, but not inflammation. Whereas aspirin and ibuprofen tackle inflammation too and are known as non-steroidal anti-inflammatory agents (NSAIDs). These drugs are known to block two enzymes - cy...

A new discovery about Acetaminophen

According to a new enzyme which is discovered, may interpret the reasons for acetaminophen acting differently from other painkillers. //Acetaminophen (paracetamol in the UK) is known to relieve pain and fever, but not inflammation. Whereas aspirin and ibuprofen tackle inflammation too and are known as non-steroidal anti-inflammatory agents (NSAIDs). These drugs are known to block two enzymes - cy...

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Discovery at Medicine Products

Discovery Inline

Description:The Discovery Inline video magnifier is an easy to use, full color Auto-focus video magnifier that is designed so that the monitor (usually a television) sits on top of the video magnifier and is not built in. This allows for a change to a larger screen if desired in the future. Also available in black and white....
Company:Clarity

Discovery Inline Plus

Description:The Discovery Inline Plus is an easy to use, full color Autofocus video magnifier that is designed so that the monitor (either a computer or a television) sits on top of the video magnifier and is not built in. It has a built in SVGA adapter allowing it to be connected to a computer so that the magnified image from the video magnifier is displayed on the computer screen. It also has a feature cal...
Company:Clarity

Discovery M150 SE Microultracentrifuge

Description:Sorvall DiscoveryTMM150 SE Micro-ultra centrifuge continues to raise the standard for rapid, small volume sample processing, now with 1,048,000 x g performance and our new 4x5mL swinging bucket rotor. DiscoveryTMM150SE processes sample sizes from 0.2 ml to 8.3 ml, with a small floor footprint, brushless direct drive, very quiet operation, rotor imbalance detection, thermo-electric cooling, and a...
Company:ThermoFisher Scientific

Discovery M120 SE Microultracentrifuge

Description:The optimal combination of performance and rapid, small volume sample processing. New 4x5 mL swinging bucket rotor. DiscoveryTMM120 SE processes sample sizes from 0.2 ml to 8.3 ml, with a small floor footprint, brushless direct drive, very quiet operation, rotor imbalance detection, thermo-electric cooling, and automatic rotor locking....
Company:ThermoFisher Scientific

Discovery 100SE

Description:DiscoverySE Centrifuges. Workhorse. All in one. With speeds up to 100,000 rpm, the new Sorvall Discovery 100SE Ultracentrifuge offers unsurpassed performance. All the advanced features come with top-of-the-line performance, powerful functionality, and revolutionary ease of use, all built into the smallest, quietest, floor model ultra on the market....
Company:ThermoFisher Scientific

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Discovery at Medicine Technology

Major New Review Supports the Broader Potential of CeNeS COMT Inhibitor Discovery Programme

CAMBRIDGE, U.K. 2nd July 2007 - CeNeS Pharmaceuticals (AIM:CEN)("CeNeS" or "the Company") the Cambridge-based biopharmaceuticalcompany today announced that a paper published this week in CNSDrugs(1) further supports the hypothesis that acatechol-O-methyltransferase (COMT) inhibitor that acts in thebrain would be a useful agent to address profound cognitivedeficits in schizophrenia and bi...

Discovery's KL-4 Surfactant Technology Demonstrates Novel Anti-Inflammatory Properties

Discovery's KL-4 Surfactant Technology Demonstrates NovelAnti-Inflammatory Properties New Surfaxin Data Presented At the 2007 Pediatric AcademicSocieties Annual Meeting WARRINGTON, Pa., May 9, 2007 (PRIME NEWSWIRE) -- DiscoveryLaboratories, Inc. (Nasdaq:DSCO) announced that new data supportingthe anti-inflammatory properties of its novel KL-4 surfactant(lucinactant) replacement tec...

Discovery Labs Presents Surfaxin and Aerosurf Data At the Pediatric Academic Societies' Annual Meeting

Surfaxin Phase 2 BPD Clinical Data Selected and Presented asPlatform Presentation Aerosurf Utilizing Chrysalis Aerosol-Generator TechnologyDemonstrates Optimal Functional Activity WARRINGTON, Pa., May 8, 2007 (PRIME NEWSWIRE) -- DiscoveryLaboratories, Inc. (Nasdaq:DSCO) announced that results from itspreviously completed Phase 2 clinical trial of Surfaxin(r)(lucinactant intr...

Major Discovery Raises Prospect of Better Patient Care By Improving Platelet Life Span

MELBOURNE, Australia, March 23, 2007 /PRNewswire/ -- Scientistsat WEHI have made a discovery with potentially profoundimplications for the care of patients, especially those undergoingcancer chemotherapy. The research team led by Drs Benjamin Kile and David Huang hasdiscovered that platelet life span is controlled by two keymolecules. The discovery raises the prospect of developing...