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Discordant in Medical News

Uganda Shows Increased HIV Discordant Couples

Health officials have pointed out that the number of HIV discordant couples, where only one partner is infected with the HIV virus//, have increased in Uganda. Commissioner for Community in the Ministry of Health, Dr Sam Okware said that HIV negative partners are at an increased risk of HIV inf...

Pay-for-performance may benefit doctors who care for very sick

...nt or related health conditions and 7,742 (63 percent) of those with other conditions not related to blood pressure. Of those with both concordant and discordant condition, 25,339 or 69.2 percent had blood pressure controlled. The researchers noted that quality of care increased with the number of other con...

Herpes medication does not reduce risk of HIV transmission

...ission Study was conducted among 3,408 African HIV discordant couples, in which one partner had HIV and the othe...of new HIV infections occur among heterosexual HIV discordant couples, many of whom are in stable partnerships a...linical trial of genital herpes suppression in HIV discordant couples is the most direct way to see if we can ma...

Breast-Specific Gamma Imaging (BSGI) Can Reduce the Number of Unnecessary Breast Biopsies When Compared to MRI

...the 37 patients who had benign biopsy results, MRI and BSGI were concordant in 16 patients yielding a specificity of 38 percent. For the patients with discordant MRI and BSGI findings, BSGI specificity was 52 percent while MRI had a specificity of 19 percent. Overall, the specificity for BSGI and MRI were 46 pe...

Omega-6 PUFAs and risk of cardiovascular disease

...dicates that intakes higher than 10% of energy appear safe and may even be even beneficial. This latter statement, says Professor Drexel, "is somewhat discordant with earlier recommendations made by other authorities". Commenting on the report, Professor Drexel adds: "This advisory is a resurrection of older...

Rare case explains why some infected with HIV remain symptom free without antiretroviral drugs

...A B57, found in previous studies to be more common in those whose HIV infection was suppressed or slowed. "The presence of this genetic spot is a discordant result that strongly contradicts theories that various genetic factors alone play a protective role in suppression," says Blankson. He notes that s...

Monogram Announces 2008 Second Quarter Financial Results

...vels but who are judged positive by conventional assays. Comparisons with local laboratory IHC or FISH results suggest significantly larger numbers of discordant results. We believe the HERmark Assay measures HER2 total protein and homodimer levels very accurately and will help physicians to make treatment deci...

Monogram Announces Commercial Availability of the HERmark(TM) Breast Cancer Assay

...2 levels but who are judged positive by conventional assays. Comparisons with local lab results by IHC or FISH suggest significantly larger numbers of discordant results. We believe the HERmark Assay measures HER2 total protein and homodimer levels very accurately and will help physicians to make treatment deci...

Lifestyle can alter gene activity, lead to insulin resistance

...ial oxidative phosphorylation in monozygotic twins discordant for obesity," appears in the online edition of the...y. Fourteen pairs (eight male and six female) were discordant for obesity, that is, one twin was obese, while th...e unable to obtain this measurement for one of the discordant pairs. Among the...

Global theme issue on poverty and human development

...rough Breastfeeding. Access the paper free online at: www.liebertpub.com/bfm Journal of Womens Health: Contraception among HIV Concordant and discordant Couples in Zambia: A Randomized Controlled Trial. Access the paper free online at: www.liebertpub.com/jwh The Journal of Alternative and Compl...
Discordant in Medical Technology

Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs

...ells can be generated using animal eggs. This is consistent with studies that indicate that eggs support nuclear remodeling, but not reprogramming of discordant animal combinations. Studies using cow and rabbit eggs clearly suggest that DNA methylation/demethylation of the donor DNA occurs in a species-specif...
Discordant in Medical Dictionary

Ventricle

...e heart as one ... International Statistical Classification of Diseases and Related Health Problems ... Double outlet left ventricle . Q20.3. discordant ventriculoarterial connection ... ... both cardioplegia and topical cooling frequently orientate to the left ventricle . ... is applied around ...
Discordant in Biological News

April 2009 Geology and GSA Today media highlights

...the hemispheres during the Last Glacial-Interglacial Transition (LGIT). Yet, this issue is still in debate, with previous studies producing apparently discordant findings. Here, Moreno et al. show evidence for a glacial re-advance and a cold episode between about 14.8 and 12.6 thousand years ago in southwest Pa...

Protein marker for schizophrenia risk

...r findings by examining alpha defensin levels in the blood of 21 twin pairs discordant for schizophrenia (where one sibling manifests the disease while the other ...re not caused by medication or progression of the disease. Because both discordant twins had elevated alpha defensins, these proteins do not indicate disease ...

Chronic fatigue syndrome impairs a person's slow wave activity during sleep

...static response. The study, authored by Roseanna Armitage, PhD, and colleagues at the University of Michigan, focused on 13 pairs of identical twins discordant for CFS. Analyses, which were restricted to the first four non-REM periods each night in order to show comparability, revealed that SWA, or other sle...

Anti-herpes treatment reduces HIV levels in women infected with both viruses

...indings will need to be confirmed by further research, and there is already a large ongoing trial that is measuring direct transmission of HIV between discordant couples in several sites worldwide. Dr Philippe Mayaud, one of Dr Nagot's colleagues at the LSHTM concludes: 'Our results have important potentia...

Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia

...et of patients with a markedly inferior response to treatment. In addition, the findings revealed a previously unrecognized phenotype characterized by discordant resistance to two widely used and mechanistically distinct antileukemic agents and provided new information about the cellular mechanisms involved in ...
Discordant in Biological Technology

Monitoring Circulating Tumor Cells With the CellSearch(R) System Can Predict Prognosis in Metastatic Breast Cancer

...67% for response/nonresponse and 74% for progression/nonprogression. In the discordant category, detection of five or more CTCs during therapeutic monitoring accu...in MBC beyond metabolic response. FDG-PET/CT was able to predict outcome in discordant instances of patients with less than five CTCs at midtherapy. Midtherapy C...

Monogram Announces 2008 Third Quarter Financial Results

...2 levels but who are judged positive by conventional assays. Comparisons with local lab results by IHC or FISH suggest significantly larger numbers of discordant results. We believe the HERmark Assay measures HER2 total protein and homodimer levels very accurately and will help physicians to make treatment deci...

CV Therapeutics Announces Presentations at American Heart Association Scientific Sessions 2008

...ssel Coronary Artery Disease in the Duke Cardiovascular Databank; Oral Presentation, Tuesday, November 11, 2008, 9:00 a.m. CST Late Sodium Current discordant T Wave and Mechanical Alternans in Left Ventricular Hypertrophy: Role of Late Sodium Current; Poster Presentation, Wednesday, November 12, 2008, 9:00 ...

MammaPrint(R) Breast Cancer Test Provides Valuable Insight for Personalized Treatment Decisions

...ity hospitals in The Netherlands. Of 427 MammaPrint gene profiles obtained from 812 patients with node-negative breast cancer, 30% of the results were discordant with the Dutch treatment guidelines. For example, some patients categorized as high risk for cancer recurrence using MammaPrint had been previously id...

Study Reaffirms Superiority of Trofile(TM) Assay

... Pfizer Study Finds Pathway's SensiTrop(TM) Assay Is discordant in Detecting HIV Tropism with Clinically Validated Trofile SO.... Pfizer concluded, based on study results, that the SensiTrop results were discordant with the results obtained using Trofile, which was used and clinically vali...

SeeSNP Propietary Analysis Advantages

...ify regions of the amplicon that produce discordant genotypes in their respective forward and ...tend to have a higher frequency of these discordant genotypes. The algorithm resolves these discordant genotypes using several sequence context...
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