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Discontinuing in Medical News

ViroPharma Incorporated Reports Second Quarter 2009 Financial Results

...rter of 2008. R&D expenses decreased $2.1 million related primarily to discontinuing the maribavir prophylactic program, offset by costs associated with manufac...spores, and higher compensation costs, offset by decreased costs related to discontinuing the maribavir prophylactic program. For the six month period, the largest ...

For Men Over 50, Odds of Eye Discomfort Increases

..., dry eye can also cause blurry or double vision. Some people get relief by drinking more water to relieve mild dehydration, switching medications, discontinuing wearing contact lenses or by using artificial tears sold over-the-counter at drugstores. Physicians may also prescribe anti-inflammatory eye drops ...

Aethlon Medical Releases Shareholder Letter to Discuss the Treatment of Hepatitis-C Virus (HCV)

...eking to supplant SOC therapy, as new candidates must demonstrate substantially greater patient benefit in order for the medical community to consider discontinuing administration of the SOC treatment regimen. As an example, Albuferon, an HCV treatment candidate from Human Genome Sciences (HGSI), recently demons...

NEJM study points to new era in hepatitis C treatment

...lower than the control group (23 percent). The most common reported side effect in the telaprevir groups was rash, and contributed to some patients discontinuing the therapy. Peginterferon alfa-2a is an antiviral drug given by injection that is also used to treat HIV and hepatitis B; it works in conjunction ...

Results from 8 late-breaking clinical trials presented at Heart Failure 2009

...ents with heart failure in a variety of healthcare systems. B-convinced is a multicentre French study designed to assess the effect of temporarily discontinuing beta-blockers in patients whose worsening heart failure leads to hospital admission. This reflects a frequent clinical dilemma but results showed tha...

Global Med Technologies(R), Inc. Licenses and Deploys its EdgeLab Laboratory Software at Eugene Andre Hospital in Lyon, France

...-site hospitals. Mr. Magnin, Head of Laboratory Service of Eugene Andre Hospital, explained, "In April, 2008 after the announcement that Agfa was discontinuing the maintenance of our HPX software, we decided to replace our product and contacted three companies whose computer solutions seemed to be suitable fo...

Results of phase III study on Labopharm's novel antidepressant published in Psychiatry (Edgemont) Journal

... of patients being treated for depression stop taking these antidepressant drugs within the first 12 months of treatment. Frequently cited reasons for discontinuing therapy include suboptimal efficacy on depression symptoms, exacerbation of sleep disturbance, increased agitation, slow onset of action, sexual dysfu...

FDA Approves ACTOplus met(R) XR (pioglitazone HCl and metformin HCl extended-release) Tablets for the Treatment of Type 2 Diabetes

...nued in patients with severe infection or in patients undergoing X-ray studies using intravenous contrast dye. Talk to your health professional before discontinuing any medications. Your health professional should perform a blood test to check for liver problems before you start ACTO plus met and ACTO plu...

IDM Pharma Reports First Quarter Financial Results

...ion in spending related to clinical development of UVIDEM, which we placed on hold in December 2007 following sanofi-aventis' notification that it was discontinuing its participation in the development of the program, $0.2 million in savings due to the closing of our Paris facility, and $0.2 million of decreased s...

New Study Shows Women Experience Significantly Less Unscheduled Bleeding With the ORTHO TRI-CYCLEN(R) LO Birth Control Pill Versus Another Pill

... side effects, more than 30 percent complained of breakthrough bleeding(3). "While unscheduled bleeding has been regarded as a leading cause for discontinuing oral contraceptives, few studies have compared two commonly prescribed oral contraceptives," said Katherine LaGuardia, M.D., director, medical affairs...
Discontinuing in Medical Technology

Dirucotide Does Not Meet Primary Endpoint in Phase III MAESTRO-01 Trial in Secondary Progressive Multiple Sclerosis

...mpleted enrollment in August 2008. Lilly and BioMS will inform regulatory agencies and provide instructions to investigators outlining the process for discontinuing the studies. Patients involved in studies who have questions should contact their study investigator. "The MAESTRO-01 study was well designed ...

Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF Presented at American Thoracic Society (ATS)

...ocol in the pirfenidone and placebo groups, respectively, and 82% and 90%, respectively, of patients did so in CAPACITY 1. The percentage of patients discontinuing treatment due to an adverse event across both studies combined was 15% and 9% in the pirfenidone and placebo groups, respectively. There was no d...

New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure

...e accomplished safely and effectively in the elderly." Benicar was well tolerated by elderly patients, with only nine of the initial 178 patients discontinuing treatment because of treatment emergent adverse events (AEs). In this trial, occurrence of drug-related AEs included: dizziness (3.4 percent), hypoten...

New Data Shows AZOR(R) (amlodipine and olmesartan medoxomil) Significantly Improves 24-Hour Ambulatory Blood Pressure

...ipine and olmesartan medoxomil-based titration regimen was well tolerated, with only three (1 amlodipine patient, 2 AZOR patients) of the 185 patients discontinuing treatment because of drug-related adverse events. In this trial, occurrence of drug-related AEs included: peripheral edema (2.2 percent) and dizziness...

AstraZeneca Submits NDA for Low Dose Aspirin/Esomeprazole Combination Product

... Annals of Internal Medicine. 2009;150;396-404. Giuseppe G.L., Biondi-Zoccai, et al. A Systematic Review and Meta-Analysis on the Hazards of discontinuing Or Not Adhering to Aspirin Among 50 279 Patients at Risk for Coronary Artery Disease. European Heart Journal . 2006;27:2667-2674. CAPRIE Stee...

American Lung Association Study to be Published in the 'New England Journal of Medicine' Finds Prescription Heartburn Medication Does Not Control Asthma Symptoms as Previously Thought

...al Officer. "Now we know with confidence that silent acid reflux does not play a significant role in poor asthma control. Talk with your doctor before discontinuing any medication, as each patient's specific needs will vary." For asthma patients with symptoms of gastric reflux such as heartburn that occurs at...

Watson Announces United States Availability of RAPAFLO(TM) (silodosin), a Novel New Treatment in Benign Prostatic Hyperplasia (BPH)

... most common drug-related side effect was retrograde ejaculation (orgasm with reduced semen), an expected effect of selective alpha blockers. Rates of discontinuing therapy due to retrograde ejaculation were low. The second most commonly-reported adverse event was dizziness. The incidence of treatment-related di...

Leader in Prostate Health Urges Prostate Cancer Screening in Face of Contradicting Data

...ison. "More time and further investigation is needed to fully understand and evaluate the impact of prostate cancer screening on mortality before discontinuing screening practices," said Dr. E. David Crawford, one of the principal investigators of the prostate component of the PLCO study and head of the Urolo...

12-Month ATLANTA Trial Data Show Sustained Benefit of Catania(TM) Stent in Treatment of De Novo Coronary Lesions

... Cardiovascular Research Foundation, presented 12-month follow-up data from the ATLANTA Trial. The results include zero percent thrombosis in patients discontinuing dual anti-platelet therapy after only 30 days. The ATLANTA Trial is a first-in-man (FIM), prospective, single center, non-randomized, single-arm stu...

Genmab A/S - Company Announcement: Genmab Reports Results of Portfolio

...e Number of Employees COPENHAGEN, October 8 /PRNewswire-FirstCall/ -- Genmab A/S (OMX: GEN) announced today that it is discontinuing development of zanolimumab (HuMax-CD4(R)). In addition, as a result of a portfolio review and assessment of the organization, Genmab is reducing its h...
Discontinuing in Medical Products

The Rousseau Chin-Lift Stabilizer

Description:...f ophthalmic procedures. Not every patient is able to maintain position on their own, and slight movements can compromise the procedure or necessitate discontinuing treatment to reposition the patient. The Rousseau chin-lift stabilizer eliminates the "drifting that occurs during surgery- allowing the surgeon to ma...
Company:Rhein Medical, Inc.
Discontinuing in Medical Dictionary

Polydipsia

... Word of the Day, and word games. Psychogenic polydipsia (compulsive water drinking) ... This cause of polyuria and polydipsia is managed by discontinuing the offending ... The term polydipsia refers to excessive thirst manifested by excessive water ... Polydipsia and polyuria are early signs...
Discontinuing in Biological News

Plastic and reconstructive surgery -- in brief

...ctive surgery. The authors suggest that patients using those antidepressants and herbs noted in the study consult with the prescribing physician about discontinuing use for up to two weeks prior to surgery. This study appears in the January 2009 issue of Plastic and Reconstructive Surgery , the official medical ...

12-month ATLANTA trial data show sustained benefit of Catania Stent

... Cardiovascular Research Foundation, presented 12-month follow-up data from the ATLANTA Trial. The results include zero percent thrombosis in patients discontinuing dual anti-platelet therapy after only 30 days. The ATLANTA Trial is a first-in-man (FIM), prospective, single center, non-randomized, single-arm ...

Clinical studies show REMICADE reduces incidence of bowel surgeries in ulcerative colitis patients

... receive placebo every 8 weeks. Overall, REMICADE was generally well tolerated in the long-term extensions, with less than five percent of patients discontinuing therapy due to an adverse event (AE). As previously reported, other notable serious adverse events (SAEs) included: prostate cancer, breast cancer, p...

Novel therapy combinations gain ground in treating hepatitis

...group (44 percent) experienced these results, indicating a significantly higher relapse rate in this group. "While many patients did relapse after discontinuing treatment, the overall sustained response rates are nevertheless promising, showing a sustained response in up to 70 percent of patients," said Stepha...

Penicillin, amoxicillin: Step aside for strep throat treatment

...on in four or five days rather than 10 days. He noted that other studies have found that anywhere from 30 to 70 percent of parents make the mistake of discontinuing antibiotic medication for their children prematurely, or giving them leftover medication later on. Sometimes it's just a misinformed attempt to give c...

Insects develop resistance to engineered crops

...nd environmental benefits, but from a resistance management standpoint they are inferior to dual-gene plants. U.S. regulatory agencies should consider discontinuing the use of those single-gene plants as soon as dual-gene plants become available," Shelton said. "And industries should be encouraged to create more d...

Bone Density Recovers After Teens Stop Injected Contraceptive

...earlier study of older women (18-39 years old.) That study found that the older women lost bone density while using DMPA and increased bone mass after discontinuing the contraceptive. However, the younger women in the current study both lost bone density and increased bone density more rapidly than did the older w...
Discontinuing in Biological Technology

MuGard Data From UK Study Shows Prevention of Oral Mucositis in Head and Neck Cancer Patients

...f oral mucositis. This condition varies from a low level of discomfort and pain, up to Grades 3 and 4 which are debilitating to the point of patients discontinuing therapy. To see a result where all or substantially all of the patients using MuGard, and using it prophylactically, are not getting oral mucositis i...

REMERON(R) Now Approved in Japan for the Treatment of Depression in Adult Patients

...ion should be given to changing the therapeutic regimen, including possibly discontinuing the medication, in patients whose depression is persistently worse, or who ...ith a monamine oxidase inhibitor (MAOI), or within 14 days of initiating or discontinuing therapy with an MAOI. In US controlled clinical trials of 6-week dura...

First oral uveitis drug reduces both inflammation and recurrence in potentially blinding eye disease

...ate the ability of LX211 (LUVENIQ, voclosporin oral capsule) to significantly improve this chronic eye inflammation. Additionally, in patients who are discontinuing potentially toxic medications for uveitis, such as the corticosteroid prednisone, LX211 actively reduces the rate of inflammatory exacerbations by 50%...

ViroPharma Incorporated Reports First Quarter 2009 Financial Results

...xpenses in the first quarter 2009 were $44.1 million for the first quarter of 2009 as compared to $27.8 million in the first quarter of 2008. Despite discontinuing the maribavir prophylactic program, R&D expenses increased $4.8 million due to costs related to the Cinryze open label trial and patient follow-up...

Poniard Pharmaceuticals Presents Final Results of Phase 1 Study of Picoplatin in Patients with Metastatic Colorectal Cancer

...nts can cause serious side effects, including severe neuropathies that prevent patients from participating in routine daily activities and may lead to discontinuing therapy," said Robert De Jager, M.D., chief medical officer of Poniard. "We are encouraged by these preliminary results, which continue to show that p...

InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF

...ed therapy per protocol in the pirfenidone and placebo groups, respectively, and 82% and 90%, respectively, in CAPACITY 1. The percentage of patients discontinuing treatment due to an adverse event was 12% and 8% in the pirfenidone and placebo groups, respectively, in CAPACITY 2, and 14% and 8%, respectively, in ...

Neogen Announces New Share Repurchase Program

... James Herbert, Neogen's CEO. "We see no fundamental reason for our stock to be at its current value. The repurchase program does not mean that we are discontinuing our strategy of using cash and borrowing power for synergistic acquisitions. This is one of several management initiatives aimed at increasing shareho...

New Study by BioTrends Highlights Anemia Practice Patterns According to Anemia Managers in Both Dialysis Units and CKD Clinics/Offices

...ferritin before holding IV iron and making more effort to keep patients on maintenance therapy (by extending dosing frequency, for example) instead of discontinuing therapy. American Regent's Venofer is the market share leader in the hemodialysis market over Watson's Ferrlecit. In the CKD market, similar to the ...

A Perfect Storm Threatens Patient Access to Specialty Medical Care

...urveyed by the American Medical Association said they will be forced to respond to the scheduled July cuts by either restricting Medicare treatment or discontinuing it altogether. Congress is now working on versions of legislation which would forestall the cuts in the near term. However, Iorio says a long-term s...

Favrille Announces Results from Phase 3 Registration Trial of Specifid in Patients with Follicular B-Cell Non-Hodgkin's Lymphoma

... the patients and their families," said John P. Longenecker, Ph.D., President and Chief Executive Officer of Favrille. "Based on these results, we are discontinuing development of Specifid and are currently evaluating steps to conserve cash and recognize value on our assets. We wish to thank all of our employees a...
Discontinuing in Biological Definition

Selective serotonin reuptake inhibitor

...e strict sense of the word (i.e. animals given free access to the drug do not actively seek it out and do not seek to increase the dose), but suddenly discontinuing their use is known to produce both somatic and psychological withdrawal symptoms, a phenomenon known as "SSRI discontinuation syndrome" (Tamam &am...
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