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Discontinuation in Medical News

NJLRA Statement in Response to Roche's Discontinuation of Accutane(R)

TRENTON, N.J., June 26 /PRNewswire/ -- Marcus Rayner, executive director of the New Jersey Lawsuit Reform Alliance, a statewide, bipartisan group of individuals, businesses and organizations dedicated to improving the state's civil justice system and advocating for legal reform in the legislature ...

Study Finds Discontinuation of Rosiglitazone Left Many Diabetes Patients Without Good Glycemic Control

JACKSONVILLE, Fla., April 14 /PRNewswire-USNewswire/ -- When concerns were raised about the safety of the diabetes medication, rosiglitazone, in May 2007, many patients and their doctors made the decision to discontinue use of the drug. A study published today in Endocrine Practice by Dr. Etta ...

A High-Density Lipoprotein Raising Drug That Has a Lower Discontinuation Rate Than That of Extended Release Niaspan Would Earn a 20 Percent Patient Share in the Dyslipidemia Drug Market

Crestor Will Remain the Clinical Gold Standard Drug Through 2016, According to a New Report from Decision Resources WALTHAM, Mass., July 29 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, ...

AdCare Health Systems, Inc. Reports Discontinuation of Definitive Merger Agreement with Family Home Health Services, Inc.

AdCare Also Reports Sale of Its Marion Assisted Living Property for a Profit of $600,000 David A. Tenwick to Join Family's Board of Directors SPRINGFIELD, Ohio, Sept. 12 /PRNewswire-FirstCall/ -- AdCare Health Systems, Inc., an Ohio corporation (Amex: ADK )...

Tamoxifen Discontinuation Rates Surprisingly High

A new study, published in the March 1, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society,// says early termination of this highly effective breast cancer drug may negatively affect treatment efficacy. At 3.5 years, the study also reveals that over one third of women have ...

Women Faces No Risk on Discontinuation of Osteoporosis Drug

A long-term study of the most widely used osteoporosis drug has found that many women can discontinue //the drug after five years without increasing their fracture risk for as long as five more years. The study on alendronate was led by researchers at the University of California, San Francisc...

Stroke Doubles Risk of Hip, Thigh Fractures

...d heels and non-slip soles, and minimizing risk factors in and around the home," he said. "A medication review by a doctor or pharmacist may result in discontinuation of drugs that increase risk of falling, such as certain hypnotics and blood pressure-lowering drugs." The study compared 6,763 people in the Nether...

Par Pharmaceutical Reports EPS of $0.71 for Second Quarter 2009

...2009, net sales from all other generic products were $39.6 million compared to $43.0 million in the first quarter. The decrease primarily reflects the discontinuation of fluticasone and a decline in volume and price of certain products, including ibuprofen, due to continued competition in the market, tempered by an ...

Uroplasty Reports First Fiscal Quarter Results

...tique product, inventory buildup in the previous quarters at one of the European distributors, a change in distributor in another European country and discontinuation of our I-Stop urethral sling product in the United Kingdom. Net loss for the first fiscal quarter ended June 30, 2009 was $1.4 million, or $0.0...

Compirion and Anderson Surgery Center Reduce OR Inefficiencies and Improve Finances

...mpliance was inconsistent from measure to measure. Specifically, Antibiotic discontinuation Within 24 Hours was at 81% while Appropriate Antibiotic was at 99%. The Co...ff in better documentation of antibiotic use. The compliance for Antibiotic discontinuation Within 24 Hours rose to 100 percent. Kim Perry said, "There were som...
Discontinuation in Medical Technology

ViroPharma Announces Discontinuation of Maribavir Phase 3 Study in Liver Transplant Patients

EXTON, Pa., Feb. 13 /PRNewswire-FirstCall/ -- ViroPharma Incorporated (Nasdaq: VPHM ) today announced that its Phase 3 trial evaluating maribavir used as prophylaxis against cytomegalovirus (CMV) disease in liver transplant patients has been discontinued, and that all patients on study drug are ...

ViroPharma Announces Discontinuation of HCV-796 Development

EXTON, Pa., April 16 /PRNewswire-FirstCall/ -- ViroPharma Incorporated (Nasdaq: VPHM ) announced today that ViroPharma and Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE ), have jointly discontinued the development of HCV-796 due to the previously announced safety issue that emerged i...

Immtech Focusing on Other Infectious Disease Programs Following Discontinuation of Development of Pafuramidine

NEW YORK, Feb. 22 /PRNewswire-FirstCall/ -- Immtech Pharmaceuticals, Inc. (Amex: IMM ) today announced that the Company will focus on its new drug discovery programs targeting Hepatitis C, and drug-resistant bacterial and fungal infections, and will discontinue all development programs for pa...

Bapineuzumab To Become the First-to-Market Disease-Modifying Alzheimer's Drug After Flurizan's Discontinuation

Most Up-to-Date Analysis of the Alzheimer's Disease Market Now Available from Decision Resources WALTHAM, Mass., July 15 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that with M...

FDA Advisory Committee Votes in Favor of SAPHRIS(R) (asenapine) for Acute Bipolar I Disorder and Acute Schizophrenia

...nce a high rate of failure due to lack of efficacy or side effects, including metabolic side effects. Poor tolerability frequently leads to treatment discontinuation even when the treatment is providing some benefit. To help manage this challenge, patients often receive multiple medications or need to switch treat...

New Results From ARTEN Study of Nevirapine Plus Tenofovir and Emtricitabine (TDF/FTC) Versus Boosted Protease Inhibitor Regimen of Atazanavir/Ritonavir Plus TDF/FTC Revealed

...ved ATV/r. The rate of serious adverse events seen at 48 weeks in patients was 9.6 percent in the nevirapine group and 8.8 percent in the ATV/r group. discontinuation due to adverse events was 13.6 percent in the nevirapine arms (51 of 376 patients), and 3.6 percent in the ATV/r arm (7 of 193 patients).(4) These res...

Mayo Clinic Proceedings: A Comprehensive Review of Addiction to Prescription Painkillers Among Patients and Physicians

...stipation. When opioid consumption is ongoing, physical dependence can and will develop. This, in turn, can lead to problematic withdrawal upon abrupt discontinuation of medication. Dependence, coupled with the feeling of euphoria these drugs can produce, leads to abuse. According to Dr. Lanier, the recent grow...

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... the initiation of, during treatment with, and for several months following discontinuation of SIMPONI. In patients who develop HBV reactivation, SIMPONI should be di...ytopenia, have been infrequently reported with SIMPONI in clinical trials. discontinuation of SIMPONI should be considered in patients with significant hematologic ab...

FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications

... and potentially fatal condition known as Neuroleptic Malignant Syndrome (NMS) has been reported with Zyprexa. If signs and symptoms appear, immediate discontinuation is recommended. Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status and evidence of autonomic instability (irregul...

New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients

... SIMPONI Despite Previous Medication or Reason for discontinuation COPENHAGEN, June 9 /PRNewswire/ -- A new anal...lead investigator. "Regardless of the reasons for discontinuation of prior anti-TNF-alpha agents, golimumab has demo...tients with active RA of 8.65 years mean duration. discontinuation of previous anti-TNF-alpha therapy was to occur at...
Discontinuation in Medical Dictionary

Smoking Cessation

... Smoking cessation is the action leading towards the discontinuation of the consumption of a smoked substance, mainly tobacco, but it may encompass cannabis and other substances as well. About 50 million America...

Retrograde ejaculation

...y, ... Retrograde ejaculation Christina Care Health System Wilmington, Delaware DE ... If retrograde ejaculation is caused by medications, discontinuation of the ... ...

Quit smoking

... Smoking cessation is the action leading towards the discontinuation of the consumption of a smoked substance, mainly tobacco, but it may encompass cannabis and other substances as well. Information and products...

Histoplasmosis

...psulatum. ... The disseminated form of histoplasmosis is usually fatal unless treated. ... Treatment of Central Nervous System Histoplasmosis . discontinuation of Maintenance Therapy ... Histoplasmosis is the most common of the endemic mycoses in ... The Canadian Lung Association - asthma, COPD, tuber...

Chemical dependence

... to a state resulting from chronic use of a drug that has produced tolerance and where negative physical symptoms of withdrawal result from abrupt discontinuation or dosage reduction. Physical dependence can develop from low-dose therapeutic... According to the current Diagnostic and Statistical Manual of ...
Discontinuation in Biological News

Termite killer lingers as a potent greenhouse gas

...rnational treaty ratified in 1987 to protect the ozone layer by reducing the production of ozone-depleting chemicals. The protocol ordered the gradual discontinuation of methyl bromide, which has strong ozone-depleting characteristics, and sulfuryl fluoride became a preferred replacement for structural fumigation. S...

New cardiology research presented at CHEST 2008

... addition, tadalafil, 40 mg, increased cardiac output and reduced pulmonary artery pressures and pulmonary vascular resistance compared with baseline. discontinuation due to adverse events was low (11 percent for tadalafil vs. 16 percent for placebo). Researchers conclude that tadalafil may provide an effective oral...

Meth exposure in young adults leads to long-term behavioral consequences

...brain degeneration when they grow older, new animal research suggests. The emergence of behavioral deficits in animals months after methamphetamine discontinuation may be relevant to human methamphetamine abusers, says Nora Volkow, MD, director of the National Institute for Drug Abuse. It suggests that even thoug...

FDA Approves New Treatment for Chronic Hepatitis B

...ts associated with the use of Baraclude were of the type typically seen with HBV therapy. They include severe, acute exacerbation of hepatitis B after discontinuation of Baraclude, headache, abdominal pain, diarrhea, fatigue, and dizziness. The labeling for Baraclude states that patients who discontinue Baraclude sh...

Bone Density Recovers After Teens Stop Injected Contraceptive

...ty. The study authors wrote that the increase in bone mineral density after discontinuation of DMPA is similar to the bone mineral density increase after a woman stops...inistered and that bone density loss may not be completely reversible after discontinuation of the drug. The FDA warning states: “Depo-Provera Contraceptive Injecti...
Discontinuation in Biological Technology

Strativa Pharmaceuticals, a Division of Par Pharmaceutical, Announces the Discontinuation of the Development Program for Pafuramidine

WOODCLIFF LAKE, N.J., Feb. 25 /PRNewswire-FirstCall/ -- Strativa Pharmaceuticals, the proprietary products division of a wholly owned subsidiary of Par Pharmaceutical Companies, Inc. (NYSE: PRX ) today announced that its development partner, Immtech Pharmaceuticals, Inc. (Amex: IMM ) has cho...

Indevus Comments on Bayer Healthcare Discontinuation of Viadur(R)

VANTAS(R) to be Only Once-Yearly Implant for Prostate Cancer in U.S. Market Indevus Reaffirms Commitment to Prostate Cancer Patients LEXINGTON, Mass., Dec. 20 /PRNewswire-FirstCall/ -- Indevus Pharmaceuticals, Inc. (Nasdaq: IDEV ) today commented on the announcement by Bayer Healthcare t...

Elagolix Successful in Six Month Lilac Petal Study; Safety and Efficacy Confirmed in Patients With Endometriosis

...hemistry, hematology, urinalysis and ECG testing evident for either dose of elagolix; treatment over six months was generally safe and well tolerated. discontinuation due to adverse events was 2.9% for 150 mg, 5.6% for 250 mg. Adverse Events reported by the 150 mg and 250 mg groups included nausea (8.7% and 8.3% res...

Sanofi-aventis Announces Second Quarter 2009 Results

...o 2,260 million, and were virtually unchanged (up 0.2%) at constant exchange rates. This figure includes euro 54 million of provisions relating to the discontinuation of various projects, following the portfolio review completed at the end of the first quarter. Selling and general expenses rose by 1.5% to e...

REMERON(R) Now Approved in Japan for the Treatment of Depression in Adult Patients

...ng clinical trials, two out of 2796 patients developed agranulocytosis, and a third patient developed severe neutropenia. All patients recovered after discontinuation of therapy. If a patient develops sore throat, fever, stomatitis or other signs of infection, along with low WBC, treatment with REMERONSolTab(R) shou...

Helix BioPharma Announces Q3 2009 Financial Results and Provides Product Development Update

..., and the risk of obtaining negative findings or factors that may become apparent during the course of research or development which may result in the discontinuation or delay of the research or development projects; the risk of technical obsolescence; the need for further regulatory approvals, which may not be obta...

Orexigen(R) Therapeutics Presents Additional NB-302 Contrave(R) Data at American Diabetes Association (ADA) 69th Scientific Sessions

...icians and their obese patients." The overall discontinuation rate due to adverse events in NB-302 was 25.9% for...most frequently observed adverse events leading to discontinuation for patients on study drug were nausea, urticaria ... have been used separately for over 20 years. The discontinuation rate due to nausea was 4.6%. This rate is lower t...

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

... develop signs and symptoms suggestive of blood dyscrasias or infection (e.g., persistent fever, bruising, bleeding, pallor) while on CIMZIA. Consider discontinuation of CIMZIA therapy in patients with confirmed significant hematologic abnormalities. An increased risk of serious infections has been seen in cli...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...ve heart failure or cardiomyopathy may occur after discontinuation of anthracycline therapy For patients...epsis occurring during neutropenia has resulted in discontinuation of treatment and in rare cases of death ...de, dose reduction, or delay in administration, or discontinuation of DOXIL may be required HFS was gene...

Bayer and Onyx Announce Nexavar Data Presentations at 45th American Society of Clinical Oncology Annual Meeting

...nd advised against breast-feeding. In cases of any severe or persistent side effects, temporary treatment interruption, dose modification or permanent discontinuation should be considered. For information about Nexavar including U.S. Nexavar prescribing information, visit www.nexavar.com or call 1.866.NEXAVA...
Discontinuation in Biological Definition

Selective serotonin reuptake inhibitor

...matic and psychological withdrawal symptoms, a phenomenon known as "SSRI discontinuation syndrome" (Tamam & Ozpoyraz, 2002). Compared to the withdrawal symptom... Tamam, L. and Ozpoyraz, N. (2002). Selective serotonin reuptake inhibitor discontinuation syndrome: a review. Advances in Therapy 19(1): 17-26. .. ...

Vaccine

...gical Evidence From Danish Population-Based Data' Pediatrics , Vol 112, No 3, September 2003 (Danish study showing continued increase in autism after discontinuation of MMR vaccine thimerosal formulations) BrianDeer.com - 'Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental di...
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