UT rheumatologists discover 2 genes related to disabling form of arthritis
HOUSTON (Oct. 22, 2007)Work done in part by researchers at The University of Texas Medical School at Houston has led to the discovery of two genes that cause ankylosing spondylitis, an inflammatory and potentially disabling
disease. The findings are published in the Oct. 21 online edition of Nat...
Humor and Hope Sustain NJ Woman Through Disabling Movement Disorder, Election Campaign
DEMAREST, N.J., Sept. 28 /PRNewswire/ -- Whether she is giving a
keynote address or visiting on the sidewalk with neighbors, Demarest
resident Esther Paik Goodhart conveys optimism and possibility. "Only in America could someone like me have the opportunities I have,"
says Goodhart with a war...
Depression May Be World's Most Disabling Disease
Global study finds it takes bigger toll than other chronic conditions
FRIDAY, Sept. 7 (HealthDay News) -- When compared with other chronic diseases, depression may well be the most disabling
disease in the world, a new global study finds.
People with chronic physical diseases such a...
York Hospital Trauma Center Upgrade
...h or permanent disability to injured patients. Accredited trauma centers must be continuously prepared to treat the most serious life threatening and disabling
injuries. They are not intended to replace the traditional hospital and its emergency department for minor injuries.
In Pennsylvania there a...
The Scleroderma Foundation Applauds Introduction of First Bill in the Senate Promoting Research and Awareness of Scleroderma
...mer (D-NY), gives hope to the estimated 300,000 Americans and their families living with this devastating disease.
Scleroderma is a chronic and disabling
connective tissue disorder resulting from an overproduction of collagen. The word "scleroderma" means hardening of the skin, which is one of the most ...
INVEGA(R) Approved as the First and Only Treatment for Schizoaffective Disorder
...ere extrapyramidal symptoms, somnolence, dyspepsia, constipation, weight increase, and nasopharyngitis.
"Schizoaffective disorder is a chronic, disabling
condition," said Husseini Manji, M.D., F.R.C.P.C., Global Therapeutic Area Head, Neuroscience, Johnson & Johnson Pharmaceutical Research & Dev...
Atlanta Sleep Medicine Clinic Views Representative Henry Waxman's Denial of Restless Leg Syndrome as a Sign of General Lack of Awareness of the Sleep Disorder
...rd certified sleep doctor who treated Gayle, agrees, "Rep. Waxman's interview is an excellent example of the dismissive nature with which truly disabling
sleep disorders have been treated all too often by the uninformed, leading to patients being mislabeled or ignored altogether, rather than receiving a...
Zucker Hillside Researchers to Receive Large Federal Grant to Test for the Early Treatment of Schizophrenia
...shown that people with schizophrenia generally do not get appropriate treatments early enough in the course of the disease and this may lead to a more disabling
form of the illness. Symptoms generally appear in late adolescence or early adulthood, and can disrupt the normal course of life and derail even the s...
Scientists Reverse Muscular Dystrophy in Mice
...ording to the MDA, myotonic (muscle-stiffening) dystrophy is one of nine forms of muscular dystrophy, a group of genetic, degenerative and potentially disabling
diseases which primarily affect voluntary muscles.
Myotonic dystrophy type 1 is the most common form of muscular dystrophy affecting adults. It is...
Cleveland Clinic Lou Ruvo Center for Brain Health Opens for Business
...n, A.L.S. and other neurodegenerative diseases who have worked so hard to make this effort a reality."
The center's mission is to prevent the disabling
symptoms of chronic brain diseases and to prolong healthy, vital aging in people at risk for dementia or cognitive disorders, through the use of Cle...
Disabling in Medical Technology
FDA Advisory Committee Votes in Favor of SAPHRIS(R) (asenapine) for Acute Bipolar I Disorder and Acute Schizophrenia
...ber 2007 through its acquisition of Organon BioSciences, which developed the product.
Schizophrenia is a chronic, disabling
brain disorder that is characterized by hallucinations, delusions and disordered thinking. The condition affects about 24 million people worldwide (o...
Dirucotide Does Not Meet Primary Endpoint in Phase III MAESTRO-01 Trial in Secondary Progressive Multiple Sclerosis
...he EDSS is the standard for measuring impairment in MS.
About Multiple Sclerosis
Multiple sclerosis (MS) is a chronic, progressive, often disabling
disease that attacks the central nervous system(ii). MS is caused by damage to myelin, the protective sheath surrounding nerve fibers in the central n...
Mayo Clinic Study Finds Earliest Evidence of Memory Decline in Middle-Aged People at Genetic Risk for Alzheimer's Disease
...onsortium support the possibility that future Alzheimer's treatments may be most effective if started in middle-aged people, years before the onset of disabling
memory and thinking problems or extensive brain pathology.
The study, which followed participants for up to 14 years, used sensitive memory a...
Mayo Clinic Proceedings Reviews Deep Brain Stimulation to Treat Psychiatric Diseases
...vascular disease in premature mortality and time lived with disability according to the review. In persons aged 15 to 44 years, depression is the most disabling
medical illness in the United States. The prevalence of major depression, known to be a chronic and relapsing illness, is approximately 17 percent, af...
CeNeRx BioPharma Obtains Rights to Novel Drug Candidate for Prevention and Treatment of Neurodegeneration Disorders
...ck effective therapies. We intend to move quickly to test CXB909 in relevant conditions, beginning with chemotherapy-induced peripheral neuropathy, a disabling
and dose-limiting side effect of cancer treatment with a relatively straightforward pathway to clinical development and regulatory review."
Study Demonstrating Lurasidone Is Effective in Patients With Schizophrenia Published in The Journal of Clinical Psychiatry
...Lurasidone exhibits little or no affinity for histamine H(1) or acetylcholine M(1) receptors.
Schizophrenia is a chronic, disabling
and serious medical illness that affects between two to three million American adults and more than 24 million adults worldwide. It affects men and w...
Back to Normal: Surgery Improves Outcomes for Spine Patients
...tive they are for patients. The trial was funded by the National Institutes of Health (NIH) in recognition of how prevalent back problems are, and how disabling
they can be. The research is meant to give patients and their physicians solid information to help guide them as they make decisions about how to trea...
Dainippon Sumitomo Pharma Announces Lurasidone Phase III Data in Patients With Schizophrenia
...c) receptors. Lurasidone has low affinity for histamine H(1), and cholinergic M(1) receptors.
Schizophrenia is a chronic, disabling
and serious medical illness that affects between two to three million American adults and more than 24 million adults worldwide. Schizophrenia affects...
Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF Presented at American Thoracic Society (ATS)
...use in IPF patients in Japan and is marketed as Pirespa(R) by Shionogi in that country.
Idiopathic pulmonary fibrosis (IPF) is a disabling
and ultimately fatal disease that affects approximately 200,000 people in the United States and Europe combined, with approximately 30,000 new cases r...
Two-Year Phase III Data Presented at AAN 61st Annual Meeting Show Positive Outcome of Cladribine Tablets in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic, inflammatory condition of the central nervous system and is the most common, non-traumatic, disabling
neurological disease in young adults. It is estimated that more than two million people have MS worldwide. While symptoms can vary, the most common sy...
Disabling in Medical Products
The Avanta Soft Skeletal Hand Implant System
Description:...e simple motions such as gripping an object or turning a key painful, if not impossible. The Avanta Soft Skeletal Hand Implants can help alleviate the disabling
effects of this disease. By incorporating advanced materials, extensive clinical experience, and joint-specific design features these implants offer ...
Company:Small Bone Innovations, Inc.
Neer II* Total Shoulder System
Description:...d for acute trauma resulting in 3 or 4 part displacement fractures, articular surface impression fractures greater than 50%, head-splitting fractures, disabling
pain unresponsive to conservative treatment due to osteoarthritis, avascular necrosis, post-traumatic arthritis, rheumatoid arthritis, sickle cell inf...
Company:Smith & Nephew, Inc. - Orthopedics
Activa Therapy System
Description:... Activa Parkinson's Control Therapy uses electrical stimulation to safely and effectively treat some of the most disabling
motor symptoms of Parkinson's disease. Activa Parkinson's Control Therapy is a safe and effective adjunctive treatment option for many Parkinson's pat...
Disabling in Medical Definition
... Abtissue pathology is a general term for a disease which, through disabling
the immune system and changing the chemical balance of the nervous system , makes the brain react as if there were an internal organ disfunction or...
Disabling in Medical Dictionary
... systemic sclerosis , primarily the. vascular and the ... systemic sclerosis in higher amounts than ... COMPREHENSIVE INFORMATION ON THIS disabling
MULTSYSTEM DISEASE FOR HEALTH CARE ... Systemic sclerosis sine scleroderma refers to visceral disease in absence of ... 303, Systemic s...
...idiopathic. ... Adductor spasmodic dysphonia (most common) is caused by involuntary excessive ... Spasmodic dysphonia (SD) is an extremely disabling
form of dystonia that is often misdiagnosed. ... Spasmodic dysphonia , also called focal laryngeal dystonia, ... Spasmodic dysphonia (SD)...
...pic shoulder stabilization is technically ... Shoulder Replacement ... Tears of the rotator cuff of the shoulder are potentially painful and disabling
conditions, and the treatments for these conditions vary widely depending upon the ... From American Family Physician on this problematic conditio...
...medical treatment is ... Ricin is widely available, easily produced, and derived from the beans ... Ricin , however, would have efficacy as a disabling
agent. ... Ricin causes poisoning by getting inside the cells of a person's body and ... Ricin poisoning does not spread from person to pe...
...he pubis is its own separate area, but later becomes fused (blended) ... If misdiagnosed or mismanaged, osteitis pubis can run a prolonged and disabling
course. ... The symphysis pubis is a fibrocartilaginous joint between the pubic rami. ... Prostatitis, chronic prostatitis and chronic p...
...> Education ... The Department of Physical Medicine and Rehabilitation at Rush focuses on restoring function in people with a wide range of disabling
injuries and illnesses. The UAB Physical Medicine & Rehabilitation Program has been ranked one of the ... UAB Programs and Centers for ...
...echnical usage in psychiatry to construct words that describe irrational, disabling
fear as a mental disorder, in chemistry to describe chemical aversions, in ...the unrelenting fear of a situation, activity, or thing ... Phobia , a disabling
type of anxiety disorder, is the most common psychi ... No everyday frigh...
...n and orthopnea . ... SCMR/SNM 2009 Appropriate Use Criteria for Cardiac Radionuclide Imaging ... cause death in a few HCM patients with severe disabling
symptoms ( orthopnea and ... The major causes of heart disease, in descending order, are 1) IHD, CHD 2) HTN ... Sx: dyspnea, orthopnea , PND, ...
...order : Causes and symptoms Diagnosis Treatment Alternative treatment Prognosis Resources Obsessive-Compulsive An explanation of the potentially disabling
mental illness where people develop anxiety-related obsessive compulsive disorder or OCD . Characteristics and treatment of obsessive compul...
...in this article for kids. ... Obsessive - compulsive disorder isn't contagious, so you can't catch it from ... An explanation of the potentially disabling
mental illness where people develop anxiety-related obsessive compulsive disorder or OCD. Obsessive compulsive disorder (OCD) is an anxie...
Disabling in Biological News
Study reveals 2 genes linked to disabling arthritis
SEATTLE An international team of researchers led by a Fred Hutchinson Cancer Research Center geneticist has discovered two genes linked to a disabling
form of arthritis called ankylosing spondylitis, a painful and progressive disease in which some or all of the spines vertebrae fuse together. The...
Protein handlers should be effective treatment target for cancer and Alzheimer's
...ontributing to Alzheimer's and other neurodegenerative diseases in which brain cell communication is interrupted.
The MCG center has evidence that disabling
molecular chaperones or the heat shock factors that control some of them, disables tumor formation in the liver and probably the breast. Researchers a...
LSUHSC research helps link schizophrenia to specific DNA region
...open doors to new and potentially better treatments."
According to the National Institute of Mental Health, schizophrenia is a chronic, severe, and disabling
brain disorder that affects about 1.1 percent of the U.S. population age 18 and older in a given year. People with schizophrenia sometimes hear voices...
Gene expression findings a step toward better classification and treatment of juvenile arthritis
...itute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health.
JIA is an inflammatory and sometimes disabling
joint disease that affects an estimated 294,000 children in the United States. At present, making a diagnosis of JIA is imprecise and based largely on...
MSU lands $2.1 million grant to take part in national autism study
...e a repository for data from nearly 3,000 families as part of the congressionally mandated Study to Explore Early Development.
"Autism is a serious disabling
condition that has been estimated to occur in one in 150 children in the United States," said Phil Reed, director of MSU's BRIC and the principal inve...
$1.6 million grant to lead development of resistance-detecting field kit
...ng kit will be designed, tested and rolled out for use by control programme staff in the regions of sub-Saharan Africa where malaria and filariasis, a disabling
and disfiguring condition also spread by mosquitoes, is endemic. The new screening tools will provide information vital for predicting the success of...
Genetic study confirms the immune system's role in narcolepsy
... Scientists funded by the National Institutes of Health have identified a gene associated with narcolepsy, a disorder that causes disabling
daytime sleepiness, sleep attacks, irresistible bouts of sleep that can strike at any time, and disturbed sleep at night. The gene has a known role in...
Oh, my aching back: Give me a shot of ozone
...the study. The estimated mean improvement for patients after treatment based on the 10-point visual analog scale (VAS), a standard tool for rating the disabling
effects of back pain, was a change of 3.9 (with 0 being no pain and 10 representing worst pain experienced). The estimated mean improvement was 25.7 p...
Stem cells replace stroke-damaged tissue in rats
...they are able to overcome some of the many challenges in translating the potential of using stem cells into reality.
"The potential to reverse the disabling
effects of stroke seems to have been proved. However the development of stem cell therapy for stroke survivors is still in the early stages and much ...
Rett Syndrome Research Trust advisor makes significant discovery
...inding protein 2 (MeCP2) in glia. MeCP2 is a protein associated with a variety of neurological disorders, including Rett Syndrome, the most physically disabling
of the autism spectrum disorders. The researchers show that MeCP2-deficient astrocytes (a subset of glia) stunt the growth of neighboring neurons. Rem...
Disabling in Biological Technology
Video: New Way RA(TM) Talk Show Premieres Online for People Living With Rheumatoid Arthritis (RA)
...ion in an accessible, online format for adults living with RA. The show also aims to raise awareness about RA, a chronic, inflammatory and potentially disabling
condition that affects more than one million Americans, 70 percent of whom are women.
(The views and opinions shared in New Way RA are those ...
SAPHRIS(R) (asenapine) Meets Primary Endpoint in Long-Term Extension Study in Patients With Predominant, Persistent Negative Symptoms of Schizophrenia
Schizophrenia is a chronic, disabling
brain disorder characterized by hallucinations, delusions and disordered th... social drive, poverty of speech or curbing of interest, which are frequent disabling
symptoms. About 24 million people worldwide (or seven in every 1,000 adult...
Advanced Life Sciences' Restanza(TM) Shows 100% Survival In Confirmatory Anthrax Study
...ontrolled efficacy studies in humans cannot be ethically conducted because the studies would involve administering a potentially lethal or permanently disabling
toxic substance or organism to healthy human volunteers. Approval of a drug under the "Animal Efficacy Rule" is subject to certain post-approval commi...
Lumbar Matrix(TM) Scan From SpineMatrix(R) Revolutionizes the Diagnosis of Low Back Pain
...mine proper treatment and can result in significant savings for patients and the healthcare industry.
Low back pain is the most common and costly disabling
condition in the United States, affecting nearly 31 million Americans. Current diagnostic methods used most frequently to detect lower back pain - su...
Savient Pharmaceuticals Reports First Quarter 2009 Financial Results
...transitionary quarter for the Company, resulting in significant progress achieved towards our commitment to bring KRYSTEXXA to the market to treat the disabling
aspects of the treatment failure gout population."
Financial Results of Operations for the Three Months Ended March 31, 2009
OncoGenex Receives Confirmation from FDA on the Design of a Second Phase 3 Trial Evaluating OGX-011 for the Treatment of Advanced Prostate Cancer
...cotics," said Cindy Jacobs, M.D., Ph.D., OncoGenex' Executive Vice-President and Chief Medical Officer. "Thus, pain is a common, often unremitting and disabling
symptom of advanced prostate cancer, and pain control is a key measurement of clinical benefit."
The planned initiation of this Phase 3 trial evalua...
Biovista Inc. Announces Positive Efficacy Results in a Pre-Clinical Trial of its BVA-101 Repositioned Drug for Multiple Sclerosis
...-101 trial in the MS EAE-MOG model
MS is a chronic inflammatory disease of the CNS with unknown etiology. It
is the most frequent non-traumatic disabling
neurologic disease among young
adults, with 12,000 new diagnoses per year in the US alone, and over 2.5
million patients worldwide. In the animal proo...
Repair Stem Cell Institute Warns About Real Cost of Embryonic Stem Cell Research
...epair Stems Cells are right now, every week, improving dozens and dozens of lives all over the world. He emphasized that "Patients stricken with disabling
diseases such as congestive heart failure, diabetes, multiple sclerosis, spinal cord injuries, cerebral palsy, muscular dystrophy, ataxia, autism, COP...
InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF
...ovided additional details of this agreement in its press release dated November 26, 2007.
Idiopathic pulmonary fibrosis (IPF) is a disabling
and ultimately fatal disease that affects approximately 250,000 people in the United States and Europe combined, with approximately 30,000 new cases r...
Watson's GELNIQUE(TM) (oxybutynin chloride) Gel 10% Approved by FDA for the Treatment of Overactive Bladder
... the night to urinate). It affects as many as 33 million adults in the U.S. - more than diabetes or asthma.
More than an "inconvenience," OAB is disabling
and associated with a marked decrease in health-related quality of life as well as higher rates of depression. The disease affects both men and women...
Disabling in Biological Dictionary
...uenced,... STUDYING GENE FUNCTION: CREATING KNOCKOUT MICE. By Hubert Walinski (August 2004) ... The gene knockout is created by selectively disabling
a specific target gene in ... C. elegans Consortium Home Page ... C. elegans Gene Knockout Consortium is to ... © Copyright 2001-2005 Celegan...