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Digests in Medical News

Discovery in amber reveals ancient biology of termites

...ried through successive stages and generations. But by the different species each specializing at what they do best the termite eats, the protozoa digests the two groups have both had extraordinary evolutionary success. "The relationship between termites and protozoa is very close and has been stabil...

Best New Product Awards Winners Named at Molecular Medicine Tri-Conference

...e Biosciences Discovery Informatics Labmatrix by BioFortis Best New Product Award Winners ClearPoint Peptides By spiking protein tryptic digests with internal heavy isotope labeled peptide standards, Mass Spectrometry becomes an absolute quantitation (AQUA) method. With a choice of heavy hydro...

Protein compels ovarian cancer cells to cannibalize themselves

...ective cells die from self-induced damage to their nuclei and DNA complex. Autophagy kills when a cell entraps parts of its cytoplasm in membranes and digests the contents, leaving a cavity. When this goes on long enough, the cell essentially eats itself until it dies, its cytoplasm riddled with cavities. ...

Melissa Biggs, Fashion Designer and Former Baywatch Actress, Teams with CSL Behring to Raise Awareness of Alpha-1 Antitrypsin Deficiency, a Commonly Misdiagnosed Respiratory Disease

...important roles is to shield the delicate tissues of the lungs by binding to neutrophil elastase, an enzyme released by certain white blood cells that digests bacteria and other foreign substances in the lungs. When a person with deficient levels of AAT inhales irritants or contracts a lung infection, the ne...

Haymarket Adds Two Cancer Journals to Its Family of Clinical Publications

...e for cancer patients," said Maniscalco. Haymarket Media Inc., based in New York City, publishes a variety of clinical journals and drug information digests for health professionals, including Monthly Prescribing Reference, Renal & Urology News, Cortlandt Forum (for primary-care physicians), The Clinical A...

American Chemical Society's weekly PressPac -- Jan. 23, 2008

...N. alata three of which can only be found in this species including useful enzymes that may inhibit bacterial growth and rotting as the plant slowly digests its prey. AD ARTICLE #2 FOR IMMEDIATE RELEASE Proteome Analysis of Pitcher Fluid of the Carnivorous Plant Nepenthes alata DOWNLOAD ARTICLE h...

Customized virus kills brain tumor stem cells that drive lethal cancer

...until they die. This self-cannibalization, called autophagy, occurs when a cell forms a membrane around part of its cytoplasm or an organelle and then digests the contents, leaving a cavity. A cell that dies from autophagy is riddled with cavities. Cells normally employ autophagy temporarily to survive wh...

Key Mechanism to Emergence of Strep Bacteria

...inogen from the human bloodstream. The bacteria attach the protein to their own surface, and then activate it into a protease an enzyme that digests proteins and is capable of destroying cells and tissues thus allowing the bacteria to break out and spread through the body. Applying the pre...

'Mix and match' of proteins may have a significant role in immunity

...ere studied by the team. T-cells use these peptides to identify a foreign body. Degradation of proteins by cell machinery called the proteasome, which digests the proteins and cuts it into pieces, leads to the formation of peptides. "The proteasome can splice peptides together," says Warren. “Every ...
Digests in Medical Technology

Are Muramyl Peptides the Magic Bullet in Probiotics?

...these results are muramyl peptides, part of the complex sugars that become available when probiotic cells are fractured in the "lysing" process, which digests the cell wall. Eastern European researchers have been using the lysing technique for several decades, but the laboratory technique is barely on biotec...

Study Shows Need to Test More COPD and Asthma Patients for Underdiagnosed Pulmonary Disease

...important roles is to shield the delicate tissues of the lungs by binding to neutrophil elastase, an enzyme released by certain white blood cells that digests bacteria and other foreign substances in the lungs. When a person with deficient levels of AAT inhales irritants or contracts a lung infection, the ne...
Digests in Medical Products

GBM -Ab EIA Auto-Immune Markers 013-GBM-48 Glomerular Basement Membrane

Description:...rified antigen does not give false positive results for patient specimens containing other autoantibodies to the GBM, in contrast to crude collagenase digests of the total GBM (2). Glomerulonephritis is a major cause of irreversible renal failure. Many forms of glomerulonephritis are caused by immunological ...
Company:ALPCO Diagnostics
Digests in Medical Dictionary

Pepsin

...nts direct from the manufacturer. Britannica online encyclopedia article on pepsin (biochemistry), the powerful enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, or ... Definition of pepsin from Webster's New World College Dictionary. ... Magnetic beads contain...

Pathogen

...t useful model for studying ... Malaria is both a treatable and preventable pathogen with the technology we have today. ... This pathogen also digests the blood cells hemoglobin stopping ... Batrachochytrium dendrobatidis is a pathogen of amphibians that has been ... Chemotaxis of the amphi...

Lactase

...fter weaning. ... Mutations that keep the lactase gene permanently switched on are ... Lactase is the enzyme in the small intestine that digests lactose (the naturally occurring sugar in milk) ... Lactase drops can be added to regular milk 24 ... Lactase - Definition of Lactase ...

Gastrointestinal

... The gastrointestinal tract (GI tract), digestive tract, guts or gut is the system of organs within multicellular animals that takes in food, digests it to extract energy and nutrients, and expels the remaining matter. The... Gastrointestinal pathology is the subspecialty of surgical patholog...

Enzyme

...ion 'backwards' by ... Buy Enzyme Supplements on Discount Prices at HerbsMD. ... Enzyme . Lactase is the enzyme in the small intestine that digests lactose (the naturally ... The E1 ubiquitin-activating enzyme lies at the apex of the ubiquitination ... We find that this enzyme controls e...

Amylase

... action of the amylase preparations isolated from microbial ... Amylase digestive enzyme products, explanation, and importance ... Amylase digests carbohydrates (polysaccharides) into smaller disaccharide units, ... Although found in many tissues, amylase is most prominent in pancreatic ju...

Aerobic bacteria

... sediment at the bottom of the ... those that need oxygen to live -- called aerobic bacteria , and ... In one year, aerobic bacteria will digests and change into carbon dioxide and water ... Todar's Online Textbook of Bacteriology presents information on Gram-positive aerobic endospore=f...
Digests in Biological News

Diuscovery in amber reveals ancient biology of termites

...ried through successive stages and generations. But by the different species each specializing at what they do best the termite eats, the protozoa digests the two groups have both had extraordinary evolutionary success. "The relationship between termites and protozoa is very close and has been stabil...

New method for detection of phosphoproteins reveals regulator of melanoma invasion

...n a three dimensional extracellular matrix environment. "Our results revealed successful selection and sequencing of phosphopeptides in proteolytic digests without affinity enrichment, as well as label-free quantitation of regulated protein phosphorylation events," concludes Dr. Ahn. "Further, we demonstr...

Texas Medical Center researchers win collaborative grants

...lace in humans and plan to assess the roles of interferon-gamma and immunity-related GTPase M, a protein similar to one found in mice that engulfs and digests bacteria, in protecting against TB. "Ultimately," they wrote in their winning proposal, "we hope to use this knowledge to identify and treat patients...

Solar-powered sea-slugs live like plants, prof says

... differently. Its main food source is a specific type of alga. "It makes a cut in the alga, sucks out the cytoplasm [the material inside the alga] and digests most of it," explains Manhart. But there's a twistit retains the plastids that trap the solar energy. These plastids remain in the slug, continue t...

Scientists discover why plague is so lethal

...ansmitted to humans via insects). This suggests that the absence of aspartase may contribute to serious disease, said Professor Brubaker. Aspartase digests aspartic acid. Because Y. pestis doesnt have the enzyme, it produces much more aspartic acid than is required by the person infected. This may cause a...

Turning fungus into fuel

... uses enzymes it creates to break down human-indigestible fibers of plants into the simplest form of sugar, known as a monosaccharide. The fungus then digests the sugars as food. Researchers decoded the genetic sequence of T. reesei in an attempt to discover why the deep green fungus was so darned good ...

Meteorology student SOARS toward excellence, overcomes obstacles

...alled Generacin Latina est cambiando el mundo" (Generation Latino: Hispanic Teens Who Are Changing the World), to mark this Spanish version of Readers digests 35th anniversary. Originally from Santo Domingo, Dominican Republic, Cspedes, who was born with Cerebral Palsy, and currently lives in Miami, Fla....

Bloodless worm sheds light on human blood, iron deficiency

...e it lives. C. elegans consumes heme and transports it into the intestine. So now you have a master valve to control how much heme the animal sees and digests via its food, Hamza explains. C. elegans has several other benefits for studying heme transport. Hamzas team could control the amount of heme the wo...

Synthetic molecules may be less expensive alternative to therapeutic antibodies, researchers find

...al molecules called peptides. Some peptides are used as medications, such as insulin or antibodies used to treat some cancers, but because the stomach digests them, most cant be taken by mouth and must be injected. By contrast, peptoids are resistant to the stomach enzymes that degrade natural peptides, ...

American Chemical Society's Weekly PressPac -- Sept. 19, 2007

...med biocatalytic microcontact printing, involves coating a nano-stamp with an enzyme a protein that speeds up chemical reactions. The enzyme then digests away a layer on the surface, leaving behind an imprint almost like an old-fashioned rubber stamp. Because no diffusion of ink is involved in the proce...
Digests in Biological Technology

Restriction Digests of DNA Isolated with the Perfectprep Gel Cleanup Kit

Restriction Digests of DNA Isolated with the Perfectprep Gel Cleanup Kit George Halley, Eppendorf 5 Prime, Inc. Introduction Agarose gel electrophoresis is used extensively to separate and an...

DOE JGI plumbs termite guts to yield novel enzymes for better biofuel production

... that comprise the tools that termites use. Our task now is to discover the metabolic pathways generated by these structures to figure out how nature digests plant materials. We can then synthesize the novel enzymes discovered through this project to accelerate the delivery of the next generation of cellul...

Bruker Announces Availability of New HUPO World Congress Proteomics Posters on Web Site

...rization by the Combination of High Resolution-CID and Ion Trap-ETD Poster T345 -- Automated LC-MALDI Analysis of Glycopeptides from Glycoprotein digests using DHB as Matrix Poster T348 -- Glycosylation Profiling of Immunoglobulin G (IgG) Subclasses Poster T384 Metabolomics -- Detailed Inv...

Exclusive WTN Interview with Don Williamson

...e sewage plant at a time Dan Williamson, president and co-founder of In-Pipe Technology Company, has a powerful new proprietary technology that digests waste. Starting at the far reaches of the sewer collection system, In-Pipe continuously adds high quantities of a special formulation of super-concent...

Green Bay entrepreneur launches new message filtering solution

...ems every five minutes in order to maintain high levels of network protection, he said. Solinus has integrated a new quarantine system that stores, digests and sends users a report so that they can delete or release messages. The latest version also integrates a new anti-virus engine that identifies and r...

Fully Automated Nano-Electrospray Coupled with a Finnigan LCQ Deca XP Plus for Sub-fmol Proteomic Analysis

...elution time (Figure 5). Overall system reproducibility was further evaluated by analyzing a mixture of all five standard protein digests at various concentrations ranging from 10 fmols to 6 pmols. Forty replicate analyses were performed. All five proteins could be identified in each of ...

Fluorescence assay for determination of protease activity

...ows the use of both clear and coloured plates depending on the assay requirements. DESCRIPTION OF ASSAY In the reaction protease digests a highly quenched BODIPY FL-casein substrate releasing fluorescent peptides. The trypsin used as standard was diluted in 10 mmol/l Tris-HCl buffer, ...

Affinity Depletion Cartridges for Removal of Human Serum Albumin and Immunoglobulins from Human Serum

...rformed on low intensity bands that did not correspond to the intact molecular weight of albumin. Figure 4 shows the mass spectra performed on peptide digests from the bands with corresponding protein identification using SwissProt. Most of these bands were identified as human serum albumin and are most like...

Achieving Reliable Protein Quantitation Results Using ICAT Reagents, MALDITOF Mass Spectrometry, and Advanced Data Interpretation Tool

...ation of 0.12 (Figure 2 and Table 1). Alternatively, the VBA software automatically looks for all possible ICAT reagent pairs if the protein digests are not previously identified. False positives could be deleted by applying statistics or re-evaluating the spectrum. For MALDI-TOF analysis, this sup...

Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma

...digested human plasma, producing a dynamic range of ~5 orders of magnitude in this single method (Figure 1, inset). Peptide MRM measurements in plasma digests thus provide a robust platform for quantitative protein biomarker early stage validation. MIDAS Workflow for Method D...
Digests in Biological Products

RNase III, E. coli from EPICENTRE Biotechnologies

Description:... Ribonuclease III (RNase III) from E. coli is an endoribonuclease that specifically digests double-stranded RNA (dsRNA) to dsRNA fragments that have 2-base, 3'-overhangs. Complete digestion of dsRNA results in dsRNA fragments of 12-15 bp. R...
Company:EPICENTRE Biotechnologies

High Molecular Weight DNA Markers from Invitrogen

Description:...stranded DNA from 9 to 48 kb on low-percentage agarose gels. The 13 bands consist of 8.3- to 48.5-kb fragments generated from restriction endonuclease digests of Lambda DNA (cIind1ts857 Sam7). Ethidium bromide staining causes the four bands identified by an asterisk (8271 bp 8612 bp 12220 bp and 19399 bp) to...
Company:Invitrogen

Blunt-ended PCR Cloning Kit / pMOSBlue Competent Cells from GE Healthcare, formerly Amersham Biosciences

Description:...licons generated by proof-reading thermostable polymerases are fully compatible.High efficiency cloning, no requirement for time-consuming restriction digests and blue/white screening.Linearized at the EcoRV site. Category: PCR & cDNA & Cloning, Products for PCR and cDNA Cloning, Cloning Kits....
Company:GE Healthcare, formerly Amersham Biosciences

DNase I Amplification Grade from Invitrogen

Description:... DNase I Amplification Grade digests single- and double-stranded DNA to oligodeoxyribonucleotides. The specific activity is >10000 units/mg. DNAse I Amplification Grade is specifically pu...
Company:Invitrogen

Chemical Inkjet Printer from Shimadzu Biotech

Description:...ivery systems deliver picoliter volumes of reagents to defined locations on the PVDF membrane (supports four different chemistries for multiple enzyme digests on the same spot). ChIP technology- Bringing Chemistry to the Protein Supports micro-scale on-membrane digestion of protein using pico to nanoliter ...
Company:Shimadzu Biotech

beta-Agarase from USB Corp.

Description:...urce: Pseudomonas atlantica Description: Beta-Agarase is useful in recovering DNA and RNA fragments from low-melting-temperature agarose. Beta-Agarase digests the agarose into oligo- and disaccharides. Tested User Friendly Properties: Heat Inactivation: 65C, 15 min Molecular Weight: 30,000 Da Optimum pH: 6.5...
Company:USB Corp.

DNase I from Invitrogen

Description:... DNase I (Deoxyribonuclease I) digests single- and double-stranded DNA to oligodeoxyribonucleotides. Ribonuclease activity has been reduced to non-detectable levels....
Company:Invitrogen

DNA Exonuclease III , E. coli from EPICENTRE Biotechnologies

Description:... Exonuclease III digests duplex DNA in a 3'-> 5' direction from a blunt end, 5'-overhang or nick, producing stretches of single-stranded DNA. Under defined reaction conditions...
Company:EPICENTRE Biotechnologies

GELase LMT Agarose Gel-Digesting Preparation from EPICENTRE Biotechnologies

Description:..., and phosphate electrophoresis buffers or GELase™ Buffer may be added to or exchanged with those buffers for higher activity. GELase Preparation digests the carbohydrate backbone of molten agarose, releasing small, soluble oligosaccharides. The nucleic acid can be used in the digested gel solution or p...
Company:EPICENTRE Biotechnologies

GELase LMT Agarose Gel-Digesting Preparation from EPICENTRE Biotechnologies

Description:..., and phosphate electrophoresis buffers or GELase™ Buffer may be added to or exchanged with those buffers for higher activity. GELase Preparation digests the carbohydrate backbone of molten agarose, releasing small, soluble oligosaccharides. The nucleic acid can be used in the digested gel solution or p...
Company:EPICENTRE Biotechnologies
Digests in Biological Definition

Digestion

.... Insects may have a crop (or the enlargement of esophagus ) while birds may develop a gizzard (or a stomach that acts as teeth and mechanically digests food). A herbivore may have a cecum that contains bacteria that helps break down the cellulose in plants. Ruminants , for example cows and ...

Enzyme

...n break down RNA into the component nucleotides Superoxide dismutase : transforms superoxide into oxygen and hydrogen peroxide Trypsin : digests proteins Tyrosine kinases : those enzymes which transfer phosphate groups to a tyrosine residue in a protein Tyrosinase Urease : hydroliz...

Restriction enzyme

...This knowledge represents more or less the essence of genetic engineering. Restriction enzymes as tools See the main article on restriction digests . Recognition sequences typically are only four to twelve nucleotides long. Because there are only so many ways to arrange the four nucleotides--...

Sequencing

... nanopore sequencing GeneEngine Methods for performing protein sequencing include: Edman degradation mass spectrometry protease digests Though polysaccharides are also biopolymers, it is not so common to talk of 'sequencing' a polysaccharide, because a symbolic linear depiction ...

Unsolved problems in biology

...n-14-containing methane, which indicates the possible presence of life on Mars. External links Science Frontiers (bimonthly newsletter) digests of reports that describe scientific anomalies. Engelmann, Wolfgang, " Unsolved problems ". " Electronic properties of DNA ". Physics Worl...
Digests in Biological Dictionary

Gel electrophoresis

...amide, or ... Gel electrophoresis is a widely used technique for ... Agarose gel electrophoresis Digital image of 3 plasmid restriction digests run on a 1% w/v agarose gel , 3 Volts/cm, stained with ethidium bromide Experiment 2: Gel Electrophoresis of DNA. What is Electrophoresis ? ...

Enzyme

...nsory integration ... Buy Enzyme Supplements on Discount Prices at HerbsMD. ... Enzyme . Lactase is the enzyme in the small intestine that digests lactose (the naturally ... Enzymes are used to speed up biochemical reactions within your body by lowering ... Enzymes have the ability to bo...

DGGE

... DGGE blotting ... DGGE - finding polymorphisms with PCR amplified DNA ... For a DGGE polymorphism screen of unknown DNA sequences, prepare digests of at ... DGGE Denaturing gradient Gel Electrophoresis for detection of single base changes polymorphisms genomic cloned and amplified DNA. ...

Agarose gels

...resis in agarose gels at alkaline pH is also used to separate ... Agarose gel electrophoresis Digital image of 3 plasmid restriction digests run ... Detailed description and movies of the preparation and uses of agarose gels ... ... in Agarose Gels . Resolution of Linear DNA on A...

Agarose Gel

..., agarose powder is mixed with electrophoresis buffer to the ... Agarose gel electrophoresis Digital image of 3 plasmid restriction digests run on a 1% w/v agarose gel , 3 Volts/cm, stained with ethidium bromide The more agarose is dissolved in the boiling water, the firmer the ge...
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