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Variation in women's X chromosomes may explain differences among individuals, between sexes

The first comprehensive survey of gene activity in the X chromosomes of women has revealed an unexpected level of variation among individuals, according to new work by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and Pennsylvania State University. The results may have important implications for understanding the differences in traits among women and...

Hirsute Or Hairless? Two Proteins May Spell The Difference

If you're a cat fancier, you're well aware that hair follicles are expendable. The product of a spontaneous mutation that caught a cat breeder's eye, le chat nu, would quickly succumb in the wild—its winter coat consists of little more than a ridge of fur down the midback and tail—and needs special care to thrive as a pet. Hairless animals in the lab, on the other hand, can be very instructive. U...

Study reveals dramatic difference between breast cancers in US and Africa

A study comparing, for the first time, breast cancers from Nigeria, Senegal and North America has found that women of African ancestry are more likely to be diagnosed with a more virulent form of the disease than women of European ancestry. Researchers from the University of Chicago, working with colleagues at the University of Calabar in Nigeria and the University of North Carolina, foun...

Big differences in duplicated DNA distinguish chimp and human genomes

A study comparing the genomes of both humans and chimpanzees has found that much of the genetic difference between the two species came about in events called segmental duplications, in which segments of genetic code are copied many times in the genome. The study appears as a companion article to the draft sequence of the chimpanzee genome published in the Sept. 1 issue of the journal Nature....

Cats' indifference towards sugar explained

Unlike most mammals, cats--both domestic and wild--are indifferent to sweets. A new study in PLoS Genetics explains the molecular mechanism behind their strictly carnivorous behavior. "We took a behavioral question and answered it molecularly," says Joseph Brand, senior author of the study and Associate Director of the Monell Chemical Senses Center. Scattered on mammalian tongues are speci...

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Single gene controls key difference between maize and its wild ancestor

While many biologists argue that teosinte, a wild Mexican grass, is the progenitor of maize, others believe that the differences between...

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New antiperspirant in action - Botox does the difference

Wet palms, frequent changing of shirts - the result of excessive sweating - known as hyperhydrosis, is always a state of embarrasment. Botox, a purified form of Botulinum toxin type A, is now a new found solution for treating hyperhydrosis. Prescription antiperspirants and some pills might help to overcome this situation, but not all people are benefited from this situation. Hence for th...

A Little Weight Loss Found To Make A Significant Difference In Men

About 30 million men in the United States suffer from erectile dysfunction. This causes a decrease in quality of life for men. With exercise and weight loss // , obese men with erectile dysfunction may be able to improve their sexual function say researchers. Researchers, conducted a study to determine if lifestyle changes, such as losing weight and an increase in physical activity, woul...

Life anticipation differences identified

According to researchers, high blood pressure is a major factor accounting for differences in life expectancy between blacks and whites. It's well known that black people live, on average, six years less than white people. And those who did not complete //high school are at a similar disadvantage compared to high school graduates. Now, for the first time, a study has identified the major health f...

Genetic differences found between Male and Female brains

As mounting research strives to understand how much of who we are is controlled by our genes, research out of UCLA offers even more understanding of what genes can do.// New findings suggest there are 54 genes that explain the different organization between male and female brains.Researchers offer evidence in their report that sexual identity is hard-wired and is determined before a person is e...

Insulin Resistance Linked To Difference In Gender

Type 2 diabetes used to be considered an adult disease, but now more children are being diagnosed with type 2 diabetes.// Research has shown girls are affected more than boys. Now, a new study shows sex-linked genes may explain this difference between girls and boys being diagnosed with type 2 diabetes. Researchers in the United Kingdom are conducting a study which aims to establish whi...

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Large Geographic Differences in EpiPen Prescriptions in the U.S., From the Journal of Allergy and Clinical Immunology

MILWAUKEE, July 11, 2007 /PRNewswire/ -- A new study suggestsstrong variation in the occurrence of anaphylaxis between thenorthern and southern U.S. Anaphylaxis is a severe allergicreaction that can be fatal without treatment with epinephrine. Thestriking north-south differences in EpiPen prescribing, a marker ofanaphylaxis risk, currently are without explanation. Theinvestigators hypoth...

Interim Data From RECORD Study Show No Significant Difference Between Avandia and Standard Therapy in Risk of Cardiovascular Hospitalization or Death

"Patients and physicians should find these data reassuring" PHILADELPHIA, June 05, 2007 /PRNewswire-FirstCall/ --GlaxoSmithKline said today that findings from an interim analysisof RECORD (Rosiglitazone Evaluated for Cardiac Outcomes andRegulation of glycemia in Diabetes), a prospective clinical trialdesigned specifically to determine cardiovascular outcomes in morethan 4,400 patients wit...

Topline Results of Phase III Study in Acute Ischemic Stroke (Dias-2) Do Not Demonstrate Difference Between Desmoteplase and Placebo

NEW YORK, May 31, 2007 /PRNewswire-FirstCall/ -- ForestLaboratories, Inc. and PAION AG today announced topline results ofthe DIAS-2 (Desmoteplase In Acute Ischemic Stroke) study with thecompound Desmoteplase. The Phase III study was designed toinvestigate the improvement of clinical outcome in patients withacute ischemic stroke treated with Desmoteplase within 3 to 9 hoursafter onset of...

Top Line Results of Phase III Study in Acute Ischemic Stroke (DIAS-2) Do Not Demonstrate Difference Between Desmoteplase and Placebo

PAION AG and US Partner Forest Laboratories, Inc. TodayAnnounced the Top Line Results of the DIAS-2 (Desmoteplase In AcuteIschemic Stroke) Study with the Compound Desmoteplase Aachen (Germany), May 31st, 2007 - PAION AG (Frankfurt StockExchange, Prime Standard: PA8) and its US partner ForestLaboratories, Inc. (NYSE: FRX) today announced topline results ofthe DIAS-2 (Desmoteplase In...

Aranesp ``145 Study'' Shows No Difference in Survival in Patients with Small-Cell Lung Cancer

THOUSAND OAKS, Calif.--(BUSINESS WIRE)--Apr 19, 2007 - Amgen(NASDAQ: AMGN) today announced the results of the "145 study", arandomized, double-blind, placebo-controlled, multicenter Phase 3study of Aranesp(R) (darbepoetin alfa) in 600 previously untreatedpatients with extensive-stage small-cell lung cancer (SCLC)receiving platinum-containing chemotherapy. The study demonstratedno statistica...