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Diclofenac in Medical News

FDA extends review of Pennsaid(R) diclofenac sodium topical solution

ST. LOUIS and MISSISSAUGA, ON, Aug. 4 /PRNewswire-FirstCall/ - Covidien (NYSE: COV ), a leading global provider of healthcare products, and Nuvo Research Inc. (TSX:NRI), a Canadian drug development company, today announced that the U.S. Food and Drug Administration (FDA) has set a new action date...

China Sky One Medical, Inc. Obtains SFDA Approval for Diclofenac Sodium Eye Drops

HARBIN, China, June 2 /PRNewswire-Asia-FirstCall/ -- China Sky One Medical, Inc. ("China Sky One Medical" or "the Company") (Nasdaq: CSKI ), a leading fully integrated pharmaceutical company producing over-the-counter drugs in the People's Republic of China ("PRC"), today announced that it o...

Nuvo Announces 2009 second quarter financial results

... symptoms associated with knee osteoarthritis. Pennsaid combines a transdermal carrier (containing dimethyl sulfoxide, popularly known as "DMSO") with diclofenac sodium, a leading non-steroidal anti-inflammatory drug ("NSAID"), and delivers the active drug through the skin directly to the site of pain. While, c...

Xanodyne Receives Approval From the U.S. Food and Drug Administration for ZIPSOR(TM) (diclofenac potassium) Liquid Filled Capsules

...ished this with the lowest available dose (25 mg) of any currently marketed diclofenac potassium product in the United States. It will also be the first and only...sule," continued Dr. Shangold. The low recommended total daily dose of diclofenac potassium delivered with Zipsor aligns with current guidance from the FDA r...

Nuvo Research and Covidien sign U.S. license and development agreement for Pennsaid(R) and Pennsaid Plus(R)

...d and Pennsaid Plus Pennsaid, Nuvo's lead product, combines a transdermal carrier (containing dimethyl sulfoxide, popularly known as "DMSO") with diclofenac sodium, a leading non-steroidal anti-inflammatory drug ("NSAID"), and delivers the active drug through the skin directly to the site of pain. Pennsaid...

Nuvo announces 2009 first quarter financial results

... symptoms associated with knee osteoarthritis. Pennsaid combines a transdermal carrier (containing dimethyl sulfoxide, popularly known as "DMSO") with diclofenac sodium, a leading non-steroidal anti-inflammatory drug ("NSAID"), and delivers the active drug through the skin directly to the site of pain. While, c...

Pennsaid(R) Phase 3 study results to be published in leading international PAIN journal

...demonstrated that Pennsaid is as effective as oral diclofenac at relieving knee osteoarthritis symptoms but with...e article, titled, "Efficacy and safety of topical diclofenac containing dimethyl sulfoxide (DMSO) compared with those of topical placebo, DMSO vehicle and oral diclofenac for knee osteoarthritis", was written by Dr. Lee S...

Exercise Physiologist and Celebrity Trainer Bob Greene Leads National Campaign to Showcase Osteoarthritis Pain Management Techniques and New Treatment Approaches

...site of pain. The amount of the active ingredient diclofenac sodium that is systemically absorbed from Voltaren...exposure from a comparable dose of an oral form of diclofenac sodium (four grams four times a day to one knee ve...aren (R) Gel Voltaren(R) Gel provides 1% diclofenac sodium in a topical gel formulation. It is a non-...

NUVO announces third quarter 2008 financial results

...t Pennsaid is an effective treatment option for the symptoms of osteoarthritis of the knee, with an improved safety profile compared to oral diclofenac while providing a similar degree of symptom relief. "The third quarter was productive for Nuvo Research in terms of the Company's product develo...

Cerimon to Conduct a Proof of Concept Study for Basiliximab for Noninfectious Uveitis, a Potentially Sight-Threatening Inflammation of the Eye

...red a Phase IIb study for moderate-to-severe ulcerative colitis in the April 2007. In late fourth quarter 2007, Cerimon's topical patch formulation of diclofenac entered two Phase II/III clinical studies for the treatment of acute musculoskeletal pain. The Company is well-financed, having closed a $70 million...
Diclofenac in Medical Technology

Pharmos Announces Clinical Results from Phase 2a Trial of Topical Diclofenac NanoEmulsion Cream

Study did not achieve statistical significance ISELIN, N.J., Nov. 19 /PRNewswire-FirstCall/ -- Pharmos Corporation (Nasdaq: PARS ) today announced results from its Phase 2a clinical trial of its topical NanoEmulsion (NE) drug delivery technology formulated with 3% Diclofenac ...

Cerimon Pharmaceuticals Announces Positive Results from a Phase II Clinical Study of Its Diclofenac Sodium Patch for Acute Pain

SOUTH SAN FRANCISCO, Calif., Sept. 11 /PRNewswire/-- Cerimon Pharmaceuticals, Inc., announced today positive results from a Phase II clinical study of its once-daily, topical 15 mg (1%) diclofenac sodium patch. The multi-center SUPPORT (Stop Underlying Pain with a diclofenac Patch and Obtain R...

Cerimon Pharmaceuticals Initiates Phase II/III Clinical Studies to Evaluate its Diclofenac Patch for Mild to Moderate Pain

SOUTH SAN FRANCISCO, Calif., Jan. 16 /PRNewswire/ -- Cerimon Pharmaceuticals, Inc., announced today it has initiated two randomized, double-blind, placebo-controlled Phase II/III clinical studies of its once- daily topical diclofenac sodium patch to treat mild to moderate pain. One of the stud...

Cerimon Pharmaceuticals Initiates Phase I Clinical Study of Topical Diclofenac Sodium Patch

Diclofenac Patch is Second Cerimon Product Candidate to Enter Clinical Studies in 2007 SOUTH SAN FRANCISCO, Oct. 2 /PRNewswire/ -- Cerimon Pharmaceuticals, Inc., announced today it has initiated a Phase I clinical study of a novel diclofenac sodium patch, the Compan...

Nuvo Research presents positive Phase III study results for Pennsaid at leading rheumatology conference

...tudy results showing that Pennsaid, Nuvo's topical diclofenac solution, is an effective treatment option for the... previous studies and show that this novel topical diclofenac solution is efficacious for the relief of symptoms...re, it had similar efficacy to orally administered diclofenac with fewer gastrointestinal, hepatic and renal adv...

China Sky One Medical, Inc. Announces 26 New Drugs in Clinical Trials

...exidine Gluconate, Cetylpyridinium Chloride and Compound Chlorhexidine, are gargles for the treatment of toothache; -- Three drugs, including diclofenac Sodium Suppositories, Paediatric Ibuprofen suppositories and Musky cream, are for pain relief; -- Three drugs, including Hydroxybenzene gel, Podo...

Cerimon Pharmaceuticals Initiates Phase II Study to Evaluate Simulect(R) (Basiliximab) for Noninfectious Uveitis

...'s lead asset in its pain portfolio is the Company's topical formulations of diclofenac. The Company is in mid-stage clinical testing with its topical diclofenac products. The Company continues to seek additional assets to add to its development pipeline and is financed by the premier investors MPM, Nomura Ph...

Data Show FLECTOR(R) Patch Yields Significant Pain Reduction for Acute Strains, Sprains and Contusions

...collected at selected times post-dose to determine diclofenac plasma levels. Results indicated that the systemic exposure to diclofenac with topical FLECTOR(R) Patch at a steady state (e...tely 4 inches by 5.5 inches and contains 180-mg of diclofenac epolamine, which has demonstrated both anti-inflam...

ISTA Pharmaceuticals Presents Results from Two Phase III Clinical Trials of Xibrom(TM) QD (Once-daily) Formulation at the American Academy of Ophthalmology Annual Meeting

...ily formulation of Xibrom was as effective as both diclofenac sodium 0.1% ophthalmic solution or ketorolac trome...vention Center, Hall D Abstract: Bromfenac Versus diclofenac Versus Ketorolac in the Treatment of Acute Pseudop...s with Xibrom twice daily, and 30 each with either diclofenac or ketorolac four times daily. Visual acuity was m...

ProEthic Pharmaceuticals Presents Positive Data for PRO-513 at American Headache Society Meeting

...g Technology (DBT), which enhances the absorption of its active ingredient, diclofenac potassium. By utilizing potassium bicarbonate as a localized buffer, DBT enables diclofenac to enter the bloodstream more quickly, resulting in a faster rate of drug a...
Diclofenac in Biological News

Recovery efforts not enough for critically endangered Asian vulture

...t. And although India, Nepal and Pakistan outlawed its manufacture in 2006, diclofenac is still available, and birds are still dying. While the death... professor at the University of North Texas in Denton. "We just need to get diclofenac out of the environment and more birds into protection before it is too late...

Cambodian vulture nests offer hope for species

...used for cattle that is highly toxic to vultures. diclofenac has lead to global population declines as high as ...rcent in slender-billed and other vulture species. diclofenac is now being slowly phased out in South Asia, but ...that assures the recovery of the vultures. Because diclofenac is almost entirely absent from use in Cambodia, th...

FDA causes unnecessary scare about common painkillers

...hat are often used to treat the pain or inflammation from arthritis. The most commonly used NSAIDs are ibuprofen (Advil®), naproxen (Aleve®), and diclofenac (Voltaren®). There are more than a dozen others, including drugs such as celecoxib (Celebrex®) that are in a special class known as selective COX-2 in...
Diclofenac in Biological Technology

Cerimon Pharmaceuticals Initiates Phase III Clinical Studies to Evaluate Its Topical Diclofenac Sodium Patch for Mild-to-Moderate Pain

SAN FRANCISCO, Feb. 25 /PRNewswire/ -- Cerimon Pharmaceuticals, Inc., announced today the Company has enrolled its first subjects in its once-daily topical diclofenac sodium patch Phase III program. The program consists of three randomized, double-blind, placebo-controlled Phase III clinical st...

Transdermal Diclofenac enters Phase 1 Clinical Trial in Humans

MELBOURNE, Australia, Nov. 12 /PRNewswire-FirstCall/ --Phosphagenics Limited ("Phosphagenics") (ASX: POH; OTCQX: PPGNY) announced today that it has initiated a phase 1 human clinical trial using its patented drug delivery system, TPM, for the targeted delivery of a leading non steroidal anti-i...

Supelco(R) and MIP Technologies Launch New SPE Product for the Selective Extraction of NSAIDs From Environmental Water

...inh, product manager of Sample Prep at Supelco. "Such compounds are among the most highly consumed pharmaceuticals in the world." Ibuprofen, diclofenac and naproxen are non-steroidal anti-inflammatory drugs that have analgesic and antipyretic activities. Clofibric acid is an active metabolite of clofi...

Cerimon Pharmaceuticals Appoints James S. Shannon, M.D., to Board of Directors

...maceutical company dedicated to developing and commercializing therapeutic products for pain and inflammation. The Company's lead product, its topical diclofenac patch, recently reported positive Phase II results and plans to initiate the patch Phase III development program in 1Q 2009. Cerimon is financed by th...

Pharmos Corporation Announces That it Will Cease Operations in Israel

...ng preclinical development of PRS-639,058 for neuropathic pain. Additionally the Company has almost completed a Phase 2a trial with its proprietary 3% diclofenac NanoEmulsion cream for use as a topical treatment for osteoarthritis pain. The Company's strategy is to seek a partner who will take the lead in bot...

Pharmos Corporation Reports 2008 First Quarter Results

...e research and development expenses going forward. A Phase 2a clinical trial with the Company's NanoEmulsion delivery technology, formulated with 3% diclofenac cream, to treat osteoarthritis of the knee commenced in June 2007 targeting 126 patients. Completion of patient recruitment is expected in mid 2008. ...

Cerimon Pharmaceuticals Names Matthew J. Meyer its General Counsel and Vice President of Business Development and Licensing

...(basiliximab) entered a Phase IIb study for moderate-to-severe ulcerative colitis in the first quarter of 2007. Cerimon's topical patch formulation of diclofenac sodium completed a Phase I study in the fourth quarter of 2007. This study will rapidly be followed by two Phase II/III studies for the treatment of a...

Pharmos Corporation Announces Board and Management Changes

...nd was very well tolerated. A second program in Phase 2a involves a clinical trial of our NanoEmulsion cream drug delivery system to deliver the NSAID diclofenac topically in patients suffering from osteoarthritic knee pain. The Company's core proprietary technology platform focuses on discovery and development...

Pharmos Corporation Announces President & COO Alan L. Rubino to Leave Company

...nd was very well tolerated. A second program in Phase 2a involves a clinical trial of our NanoEmulsion cream drug delivery system to deliver the NSAID diclofenac topically in patients suffering from osteoarthritic knee pain. The Company's core proprietary technology platform focuses on discovery and development...

Pharmos Corporation Reports 2007 Third Quarter Results

...tion with the Company's commencement in June 2007 of a Phase 2a clinical study of its topical NanoEmulsion drug delivery technology formulated with 3% diclofenac as a treatment for osteoarthritis. Up to eight centers in Israel will enroll a total of approximately 126 subjects over a nine-month period. Gross exp...
Diclofenac in Biological Dictionary

Renal portal system

...glomeruli in quail, rather than an effect on the renal portal system . ... tubules is supplied by the renal portal sys- tem, the effect of diclofenac on this system ... white represent the renal portal system and the black ... The renal portal system takes the blood from the caudal...
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