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Desensitization in Medical News

Clopidogrel Allergy Can Be Tackled By Methodical Desensitization

A study that is to be presented at the 29th Annual Scientific Sessions of the Society for Cardiovascular Angiography and Interventions (SCAI) says that following// a methodical desensitization protocol might help patients who are allergic to anti-clotting medication that is vital to prevent the for...

New OTC Allergy Treatment Available to Food Allergy Sufferers

... Allertherapy(TM) Makes Allergy desensitization an Accessible and Cost-Effective Option FORT COLLINS, Colo., March 26 ...centration, which decreases the potential for bad reactions, yet allows for desensitization to occur. The sublingual application permits rapid absorption, and reduces ...

Early Detection Remains Key in Updated NCCN Guidelines for Ovarian Cancer

...s commonly used in ovarian cancer, the NCCN Guidelines Panel felt it was important to provide information on allergic reactions and recommendations on desensitization regimens. "Most patients experiencing allergic reactions are able to be desensitized allowing for continued chemotherapeutic treatment, which is ...

Studies show children can complete treatment for peanut allergies and achieve long-term tolerance

.... So far, the oral immune therapy appears to be working. "We see initial desensitization effects of the treatment are real," Burks says. "Those children are now abl.... We have to wait for the studies to show the treatment is safe, and to see desensitization start to work. We also want to know the therapy works long term." Burks ...

Seabrook House Embraces the New Year with New Programs

...ry sponsor. They will have access to 12 hours of clinical group sessions, individual counseling, family therapy, Equine therapy, EMDR -- Eye Movement desensitization and Reprocessing - and yoga. This program will follow the model of Seabrook West, Seabrook House's 90 day extended care program for men. Also, S...

Stallergenes Partners With Catalent and the Medical House for Commercialization of Adrenaline Autoinjector in Europe

...devotes 20% in raw data of its turnover to Research and Development and is actively involved in the development of a new therapeutic class: sublingual desensitization tablets. In 2007, Stallergenes realised sales of EUR 147 million, mainly achieved in the European markets. Stallergenes is listed on Euronext Pari...

Dartmouth researchers say too many children see extreme violence in movies

...e to media violence and aggression and violence in children. For example, playing video games can lead to changes in attitudes and behavior as well as desensitization to actual violence. "We know so much about the harmful effects of exposure to violent media content, but how much exposure children actually get ...

Independence Day Can be Terrifying for Pets

... as early as possible. There are a number of ways to approach this problem, including medications, but many require time and preparation. For example, desensitization programs can reduce a dog's response to fireworks, but that can take weeks or months. "There are many dogs that experience a great deal of fear and ...

Treatment at an AASM accredited sleep center improves long-term CPAP compliance

...st and a certified respiratory therapist and were educated about OSA. CPAP desensitization and mask fittings were conducted within the center, if indicated, and patie...ce improved in these patients and more patients availed of mask changes and desensitization in the compliant group. Older age was related to increasing compliance. ...

Health Woes Not Always to Blame for Chronic Cough

...chronic cough through a positive feedback process. "Effective control of cough requires not only controlling the disease causing the cough but also desensitization of cough pathways," the authors concluded. The second paper focused on management of chronic cough. Much of the available evidence suggests that is...
Desensitization in Medical Technology

Stallergenes S.A.: Positive Results From a Phase IIb/III Clinical Trial on the House Dust Mite Desensitization Tablet

ANTONY, France, April 29 /PRNewswire-FirstCall/ -- Stallergenes S.A. announces the release of the first year outcome of its phase IIb/III clinical trial (VO 57.07) on a sublingual house dust mite desensitization tablet. "We are very pleased with the outcome of this study, which is the f...

Circassia Begins Phase II Clinical Trial With Ragweed Allergy Therapy

...ecialty biopharmaceutical company focused on the field of allergy. The company's range of allergy therapeutics utilizes its proprietary T-cell epitope desensitization technology, ToleroMune. Circassia's products offer potential major clinical benefits compared with existing therapies, and consequently have significa...

Circassia's Allergy Therapy Begins Phase II Clinical Trial in Asthma Patients

...ecialty biopharmaceutical company focused on the field of allergy. The company's range of allergy therapeutics utilizes its proprietary T-cell epitope desensitization technology, ToleroMune. Circassia's anti-allergy products offer potential major clinical benefits compared with existing therapies, and consequently h...

Got Pain?

...the fingers to curl toward the palm) and nerve pain, explains Dr. Osterman. But new treatments, like arthroscopy, collagenase injections, nerve wraps, desensitization techniques, therapeutic techniques and neuroleptic medications -- both oral and injectable -- (examples include Vitamin C and Botulinum injections) ha...

STALLERGENES: Oralair(R) Grasses Obtains a Pediatric MA(1) in Germany

...ons for Oralair(R) Grasses, sublingual tablets for desensitization to grass pollens. The marketing authorizati...s an important milestone in the field of pediatric desensitization therapy. Thanks to the quality of the clinical tri...during the development of the tablet, grass pollen desensitization therapy has now achieved a level of evidence so fa...

Circassia Completes Patient Recruitment for Phase II Clinical Trial of Toleromune(R) Allergy Treatment

...nd even life-threatening adverse reactions that are associated with current desensitization treatments." About Circassia Circassia is a specialty biophar...roducts target allergies utilizing the company's proprietary T-cell epitope desensitization technology, ToleroMune. In addition to ToleroMune's potential therapeutic b...

Anesiva Announces Adlea ACTIVE-1 Phase 3 Clinical Results, Ceasing of Zingo Commercial Operations and Restructuring

...a highly purified form of capsaicin (derived from chili peppers) that acts on TRPV1 receptors, expressed most densely in C-fiber neurons. Importantly, desensitization of the TRPV1 receptors blocks noxious pain with no effect on adaptive pain or position sense. Adlea generally has a short half-life of 1 to 2 hours. I...

Circassia Initiates Further Phase II Clinical Study of Toleromune(R) Anti-Allergy Technology

...nsdowne Partners, Goldman Sachs and Invesco Perpetual. Circassia's lead products target allergies utilizing the company's proprietary T-cell epitope desensitization technology, ToleroMune. The company is also developing its ToleroTrans organ anti-rejection technology, which uses a similar approach to down-regulate...

Circassia Achieves Successful Phase II Clinical Results With Toleromune(R) Anti-Allergy Technology

...nsdowne Partners, Goldman Sachs and Invesco Perpetual. Circassia's lead products target allergies utilizing the company's proprietary T-cell epitope desensitization technology, ToleroMune. The company is also developing its ToleroTrans organ anti-rejection technology, which uses a similar approach to down-regulate...

Anesiva Commences Phase 2 Trial of Adlea(TM) in Arthroscopic Shoulder Surgery

... neurons, which transmit long-term pain, by binding to and desensitizing the TRPV1 pain receptors. This leads to a prolonged, reversible and localized desensitization of the pain fibers. The drug generally has a short half-life of 1 to 2 hours, and is undetectable in the blood after 24 hours. Adlea's short duratio...
Desensitization in Medical Dictionary

Desensitization

Systematic desensitization is a type of behavioral therapy used in the field of psychology to help effectively overcome phobias and other anxiety disorders. More specifically, it is a type of Pavlovian therapy / classical conditioning therapy developed by a South... Desensitization ...

Eye movements

... movement (disambiguation) ... Eye movements are thus very important for visual perception, and any failure to ... Eye Movement desensitization and Reprocessing, an information processing psychotherapy ... Saccade – a fast movement of an eye , head, or other part of an ... The first ...
Desensitization in Biological News

Studies point to novel target for treating arrhythmias

...s "willing" to bind calcium prevented arrhythmias. The drug they used is limited to in vitro testing, but the studies validate the concept of calcium desensitization as a way to prevent or block arrhythmias. "The next step is to look for agents that have a desensitizing effect and then try them therapeutically, fi...

Gene therapy reversed heart damage in heart failure

...iuseppe Rengo, M.D., a post-doctoral fellow. "The theory is that by inhibiting this kinase, the heart will recover partially due to reversal of the desensitization of the -adrenergic receptors," Dr. Koch said. "The expression of ARKct leads to a negative neurohormonal feedback that prevents the he...

NIH selects LIAI for major study on allergy molecular causes and possible treatments

... variety of allergic diseases. Currently, many allergy sufferers receive desensitization treatments, whereby the patient is given increasing doses of the substance ...ned. If this proves true, it could produce the same effects as the current desensitization therapies, but in a much shorter period of time, and without the allergic s...

Rhythmic breathing adapts to external beat through 'brain calculus'

...ndary form of habituation, called desensitization. desensitization engages memory to record the habituation and then ...n. A study of respiratory rhythms first exposed desensitization as a type of nonassociative learning. If you take ...rest. After a moment, however, habituation and desensitization kick in. The vagus nerve, which detects when the l...

Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness

...acellular signals. Once activated the receptors are quickly turned-off by an enzyme called a G protein-coupled receptor kinase. This process is called desensitization and can limit the effectiveness of many drugs, such as opiates for pain and adrenaline for asthma, and is further associated with numerous diseases in...

Pilot study successful in taming allergic reactions to food

...actions. The researchers now are conducting two follow-up food allergy desensitization studies, Burks said. In one study, subjects receive higher doses of egg to ...second study focuses on children who are allergic to peanuts, to see if the desensitization approach can build their tolerance and decrease the severity of their react...

Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy

...eart failure patients, chronic stress leads to an excess of adrenaline, over-stimulating beta-adrenergic receptors, a process that results in receptor desensitization and loss, Rockman said. Earlier work by Rockman's team identified PI(3)K as being required for beta-adrenergic receptors to be drawn back into the ...

Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs

...suggested that the regulatory protein beta-arrestin 2, normally involved in desensitization of receptor signals, is required for normal dopamine-related behavior. They...nt evidence for the emerging concept that beta-arrestin 2 not only controls desensitization but also participates in slow synaptic transmission here by acting as a sca...
Desensitization in Biological Technology

STALLERGENES: Strong Sales Growth in 1st Half-Year: up 12% Full-Year Guidance Maintained

... results of the phase III clinical study carried out on the house dust mite desensitization tablet. Moreover, the mutual recognition procedure for Oralair(R) (g...rhinoconjunctivitis and allergic asthma. A pioneer and leader in sublingual desensitization treatments, Stallergenes devotes 21% (gross) of its sales to Research and D...

Stallergenes : Investor Meeting: Webcast is Available

...the prevention and treatment of allergy-related respiratory diseases, e.g. rhinoconjunctivitis and allergic asthma. A pioneer and leader in sublingual desensitization treatments, Stallergenes devotes 21% (gross) of its sales to Research and Development and is actively involved in the development of a new therapeutic...

STALLERGENES: 2008: Strong Performance

...ir(R) program is the new umbrella marketing name of the range of sublingual desensitization tablets). Net R&D expenditure thus increased by 26% and represent 17.5%...rhinoconjunctivitis and allergic asthma. A pioneer and leader in sublingual desensitization treatments, Stallergenes devotes 21% (gross) of its sales to Research and D...

Stallergenes Signs an Exclusive Partnership Agreement With Solvay Pharmaceuticals for the Promotion and Distribution of its Products in Russia and the CIS*

...lvay Pharmaceuticals will enable us to promote the desensitization standardized products, and notably the sublingual ... collaborating with the world leader in sublingual desensitization therapy and making its innovative standardized pro...llergic asthma. A pioneer and leader in sublingual desensitization treatments, Stallergenes devotes 21% of its turnov...

Stallergenes: 2008: Sales Up 16% - Excellent Performance - Guidance Exceeded

...the prevention and treatment of allergy-related respiratory diseases, e.g. rhinoconjunctivitis and allergic asthma. A pioneer and leader in sublingual desensitization treatments, Stallergenes devotes 20% of its sales in gross resources to Research and Development and is actively involved in the development of a new ...

Anesiva Phase 3 Trial of Adlea Meets Primary Endpoint to Significantly Reduce Pain After Total Knee Replacement Surgery

...a highly purified form of capsaicin (derived from chili peppers) that acts on TRPV1 receptors, expressed most densely in C-fiber neurons. Importantly, desensitization of the TRPV1 receptors blocks noxious pain with no effect on adaptive pain or position sense. Adlea generally has a short half-life of 1 to 2 hours. ...

Stallergenes: Launch of a Phase III Clinical Trial in Adults for Oralair(R) Grasses in the United States Operating Income Expected to Remain Stable in 2009

...rhinoconjunctivitis and allergic asthma. A pioneer and leader in sublingual desensitization treatments, Stallergenes devotes 20% of its turnover in raw data to Researc...actively involved in the development of a new therapeutic class: sublingual desensitization tablets. In 2007, Stallergenes had a turnover of 147 million euros and pr...

Circassia Acquires North American and Japanese Rights to Dopexamine

...nsdowne Partners, Goldman Sachs and Invesco Perpetual. Circassia's lead products target allergies utilizing the company's proprietary T-cell epitope desensitization technology, ToleroMune(R). The company is also developing its ToleroTrans(R) organ anti-rejection technology, which uses a similar approach to down-re...

Anesiva Announces Second Quarter 2008 Financial Results and Update

...dy demonstrated that a single dose of Adlea caused a prolonged decrease in specific neuronal markers and the TRPV1 receptor, suggestive of desensitization of the nerve fibers, which gradually reversed several weeks following treatment. Additional Development -- Anesiva out-licensed worldw...

STALLERGENES : Further Profit Growth Acceleration of R&D Expenditure

...tivitis, rhinitis and allergic asthma. A pioneer and leader in sublingual desensitization treatments, Stallergenes devotes 16% of its sales to Research and Developme...lly involved in the development of a new therapeutic family, the sublingual desensitization tablets. Stallergenes realised 2007 sales of EUR 147 million, of which ha...
Desensitization in Biological Definition

Proprioception

...lboard). The proprioceptive sense can become confused because humans will adapt to a continuously-present stimulus; this is called habituation or desensitization . The effect is that it seems as though proprioceptive sensory impressions disappear, just as a scent seems to disappear when a person smells it for ...

Synapse

... the pre-synaptic or post-synaptic membrane. This " re-uptake " prevents " desensitization " of the post-synaptic receptors and ensures that succeeding action potenti...elicit the same size EPSP. The necessity of re-uptake and the phenomenon of desensitization in receptors and ion channels means that the strength of a synapse may in e...
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