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Derivatization in Biological News

2009 ASPB Summer Undergraduate Research Fellowship award announcement

...Dr. Miller for their encouragement and support. Emily Lin, University of Maryland Mentor: Ganesh Sriram Gas Chromatography-Mass Spectrometry derivatization for Metabolic Flux Analysis I am really excited to receive the ASPB SURF award. First, I thank ASPB for this fellowship to continue my research in m...
Derivatization in Biological Technology

Detection of Morphine and Morphine-Glucuronide in Saliva or Urine with a Rapid and Simple Method Without Derivatization on the Varian 500-MS

Jason S. Wood, Ph.D. Varian, Inc. Introduction Testing for drugs of abuse (DoA) is becoming more prevalent in various environments, including forensics and social justice environments as well as in sporting events. Non-heroin opiates such as morphine, oxycodone, and...

Quantitation of Acrylamide in Food Samples on the Finnigan TSQ Quantum Discovery by LC/APCI-MS/MS

...for the analysis of acrylamide, this method requires extensive sample cleanup and chemical derivatization.6 The advantage of LC/MS/MS is that chemical derivatization is not necessary prior to acrylamide analysis. To date, most LC/MS/MS methods for the assay of acrylamide have utilized an electrospray ioni...

Analysis of ()-11-Nor-9-Carboxy-Delta-9-THC in Urine by Negative Ion Electrospray LC/MS/MS

...metabolite testing, requires time consuming sample derivatization prior to analysis. LC/MS provides the same specificity and sensitivity without the need for a derivatization process. A simple, high throughput LC/MS...he method eliminates the need for a time-consuming derivatization step which can take an hour or more. The Varian 12...

High sensitivity quantitation of metabolites of nitrofuran antibiotics in animal tissue using LC/MS/MS

...les were prepared by homogenization, organic solvent washes, hydrolysis and derivatization followed by liquid-liquid (L-L) extraction before analysis. The limits of d...itrofuran antibiotics in chicken tissue via their metabolites. The one step derivatization improves non-specific fragmentation and poor MS detection sensitivity of th...

Determination of the Chloramphenicol residues in milk and milk products using LC/MS/MS

..., before the samples can be analyzed. LC/MS, on the other hand, requires no derivatization and can be directly analyzed, minimizing possible derivatization problems, saving time, and preventing compound losses. This paper...

Quantification of the Purinergic Receptor P2X3 using ICAT and Orthogonal 2D LC-MS/MS with an Ion Trap Mass Spectrometer

...us Report (composite) . Results To monitor the effectiveness of ICAT derivatization of P2X3, Western blot analysis was done using sample preparations before and after ICAT labeling (Figure 3). The results shown in Fi...
Derivatization in Biological Products

ATTO-TAG CBQCA derivatization reagent (CBQCA; 3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde) from Molecular Probes (Invitrogen)

Description: Molecular Probes is pleased to offer the ATTO-TAG series of reagents for the ultrasensitive detection of primary amines. Developed by Novotny and collaborators at Indiana University, the ATTO-TAG reagents are similar to the important reagents o-phthaldialdehyde (OPA), naphthalene-2,3-dicarboxaldehy...
Company:Molecular Probes (Invitrogen)

ATTO-TAG CBQCA Amine-Derivatization Kit from Molecular Probes (Invitrogen)

Description:... obtaining ultrasensitive detection using chemical derivatization reagents, including the ATTO-TAG reagents, is that...d technique employs ATTOTAG FQ for the solid-phase derivatization of dilute solutions (10-8 M) of peptides that have...CD membranes. This method permits the quantitative derivatization and analysis by capillary electrophoresis of only ...
Company:Molecular Probes (Invitrogen)

ATTO-TAG FQ Amine-Derivatization Kit from Molecular Probes (Invitrogen)

Description:... obtaining ultrasensitive detection using chemical derivatization reagents, including the ATTO-TAG reagents, is that...d technique employs ATTOTAG FQ for the solid-phase derivatization of dilute solutions (10-8 M) of peptides that have...CD membranes. This method permits the quantitative derivatization and analysis by capillary electrophoresis of only ...
Company:Molecular Probes (Invitrogen)
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