Source of molecular triggers in cutaneous T cell lymphoma identified
In a study published in the journal Blood, Yale scientists identify the molecular triggers that stimulate Cutaneous T Cell Lymphoma (CTCL) cells to clonally expand into large populations of malignant lymphocytes. CTCL is the most common adult malignancy of T lymphocytes, the white blood cells of the immune system. Finding CTCL triggering factors has been a major goal of Richard L. Edelson...New, automated tool successfully classifies and relates proteins in unprecedented way
For the first time, researchers haveautomatically grouped fluorescently tagged proteins fromhigh-resolution images of cells. This technical feat opens a new way toidentify disease proteins and drug targets by helping to show whichproteins cluster together inside a cell.The approach, developed by Carnegie Mellon University, outperformsexisting visual methods to localize proteins inside cells...Fox Chase Cancer Center scientists identify immune-system mutation
A team of Fox Chase Cancer Center scientists led by immunologist Dietmar J. Kappes, Ph.D., has identified the genetic mutation that keeps a mouse strain from developing white blood cells, or lymphocytes, called helper T cells. The report by Kappes and his colleagues appears in the Feb. 24 issue of Nature. Kappes' laboratory first discovered the mice with this naturally occurring defect in...Key molecule in plant photo-protection identified
Brain cells in a mouse model of Alzheimer'sdisease have surprised scientists with their ability to recuperateafter the disorder's characteristic brain plaques are removed.Researchers at Washington University School of Medicine in St. Louisinjected mice with an antibody for a key component of brain plaques,the amyloid beta (Abeta) peptide. In areas of the brain whereantibodies cleared plaque...Study identifies predictors of HIV drug resistance in patients beginning triple therapy
A scientist at the Marine BiologicalLaboratory (MBL) has published the results of an EPA-funded clam embryostudy that supports her hypothesis that, when combined, the pollutantsbromoform, chloroform, and tetrachloroethylene--a chemical cocktailknown as BCE--can act synergistically to alter a key regulator in nervecell development. While scientists have previously studied the effectsof these...ALDEFLUOR, Stem Cell Identification, Kit from StemCell Technologies, Inc.
Description:ALDEFLUOR Stem Cell Identification Kit. ALDEFLUORs proprietary technology comprises a substrate for the enzyme aldehyde dehydrogenase (ALDH) that is highly expressed in all viable stem cells, making ALDH an extremely useful marker for counting and isolating viable stem cells....Protein Identification Service via MALDI MS/MS from Protagen AG
Description:This protein identification Service includes 1. Scanning of gel(s) 2. Excision/picking of protein spots 3. High-sensitive tryptic in-gel digestion and peptide extraction 4. Preparation of samples for MALDI-MS 5. Acquisition of PMF (Peptide Mass Fingerprint) spectra via MALDI-MS (Bruker ultraflex TOF/TOF) 6. Acquisition of PFF (Peptide Fragmentation Fingerprint) spectra via MALDI-MS/MS (Bruker ult...Reverse Transcriptase AMV; RNA dependent DNA polymerase from Roche Applied Science
Description:Request Info...Human Mesenchymal Stem Cell Functional Identification Kit from R&D Systems
Description:Request Info...Big Blue Rodent Cell Cultures for Mutagenesis Studies
Rat and mouse embryonic cell lines are useful for in vitro mutagenesisstudies Stratagene Cloning Systems, Inc. The Big Blue rat cell line and the Big Blue transgenic mouse embryoniccell line are useful for in vitro mutagenesis studies. These cell lines are partof the Big Blue transgenic rodent mutagenesis assay system...Identification of Differentially Expressed Gene Products with the CastAway System*
CastAway precast gels for fast analysis of RAP-PCR and differentialdisplay Stratagene Cloning Systems, Inc. Stratagenes new CastAway precast sequencing gels were used to detectand isolate differentially expressed gene products amplified by the RNAarbitrarily primed polymerase chain reaction (R...TKB1 Cells Identify Receptor Tyrosine Kinase Interacting Proteins
Institute for Molecular Biology and Biotechnology, McMaster University,Ontario, Canada GST-fusion proteins expressed in TKB1 bacteria are used to affinity purifycellular proteins, which interact with a specific autophosphorylation site onthe Erb...Potential New Cancer Gene Identified
A Johns Hopkins University research team has discovered a new family of genes that contributes to the process of malignancy, shedding new light on the abnormalities that give rise to the aggressive childhood cancer, Burkitt's lymphoma - as well as lymphoma, leukemia, prostate, ovarian, lung, and breast cancer. Characterized by rapidly growing abdominal tumors, Burkitt's lymp...Laboratory Testing Can Identify Risk of Pre-Term Labor and Delivery
A test for fetal fibronectin can predict whether a pregnant woman is at risk for early labor and delivery. Those at high risk for pre-term births are women with previous pre-term deliveries, those with multiple gestation pregnancy, and those who suffer from diabetes and/or hypertension. The current approach for finding whether a woman will go into premature labor is the use of a clinical...Genetic Dentistry: Your Dentist may be able to grow you a new set of Teeth.
Researchers at the University of Texas Health Science Center at San Antonio have successfully regrown mouse teeth in a petri dish from single mouse cells - and they think humans are next. They hope to push the research in the direction where they could take initial tissue from a [human] patient, put it in a culture dish and grow a tooth for them.To accomplish this seemingly futuristic fea...Now you can identify Sperm and Egg donors
The British government, in a landmark decision, has ruled that henceforth donors of sperms and eggs can be identified if both the donor and recipient desire so. However if the donor feels not to reveal his/her identity, it will not be revealed. Prior to this ruling the identity of the donors of sperms and eggs have always been withheld. This would be a major ruling with far reaching conse...Clinton's new problem - Is the outgoing American president suffering from skin cancer?
The outgoing U.S. president Bill Clinton will be remembered as one of the most controversial presidents ever. He created history by becoming the first American president in history to be impeached by the House of Representatives. Only because he managed to win at the senate did he save himself and his country further damage. He has been the center of many burning controversies throughout...Cutting Burr with Dental Shank
Description:Cutting Burr with dental shank, tungsten carbide, 0,7 mm, ISO-No. 007, packing unit 10 pieces....The Provident Hip System - Hooded Liner
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Description:The Precedent establishes a new generation of revision hip stems....CV Therapeutics Identifies Potential Anti-Diabetic Mechanism of Action for Ranexa
-- New Preclinical Information May Correlate with Clinical HbA1cReductions Observed in Phase 3 CARISA and MERLIN TIMI-36 ClinicalTrials -- PALO ALTO, Calif., July 9, 2007 /PRNewswire-FirstCall/ -- CVTherapeutics, Inc. announced today that researchers have completedpreliminary preclinical studies showing that ranolazine increasedglucose stimulated insulin secretion in pancreatic beta cells...Molecular Target of Bradmer's Neuradiab Further Validated by Independent Findings
TSX: BMR TORONTO, July 10, 2007 /PRNewswire-FirstCall/ - BradmerPharmaceuticals Inc., a biopharmaceutical company dedicated to thedevelopment and commercialization of cancer therapies, todayannounced that new research published by an independent team inBasel, Switzerland validates tenascin as an important moleculartarget for the development of new treatments for glioblastomamultiforme (G...NIEHS Researchers Identify Enzyme Critical in DNA Replication
BETHESDA, Md., July 5, 2007--In this weeks issue of Science,researchers from the National Institute of Environmental HealthSciences (NIEHS) and Umeö University in Sweden report animportant discovery about a critical new role that an enzyme calledDNA polymerase epsilon plays in replicating DNA in higher organismssuch as yeast and perhaps even humans. The study places us one ste...Rosetta Genomics and Weizmann Institute Scientists Identify Role of microRNA in Cancer Suppression
Findings Published in Molecular Cell Show Potential of microRNAs asNovel Cancer Drug Targets REHOVOT, Israel and NORTH BRUNSWICK, New Jersey, July 05, 2007/PRNewswire-FirstCall/ -- Rosetta Genomics Ltd , a leading microRNAcompany, announced today research published in the journalMolecular Cell by scientists from the Weizmann Institute of Scienceand Rosetta Genomics . The findings suggest...Researchers Discover Method for Identifying How Cancer Evades the Immune System
PHILADELPHIA, July 3, 2007-- One of the fundamental traits of atumor – how it avoids the immune system – might becomeits greatest vulnerability, according to researchers from theUniversity of Southern California. Their findings,demonstrated in human breast and colorectal cancers, indicate thata technique for determining a tumor’s “immunesignature,” could be...Noninsulin-dependent diabetes mellitus
Alternate Names Diabetes</ ...Insulin-dependent diabetes mellitus
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