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Dendritic in Medical News

“Provenge”, Dendritic cell vaccine for Prostate Cancr

An experimental dendritic vaccine has shown significant prognosis and extension of lifetime of men with prostate cancer. The vaccine Provenge is based on dendritic cells, which help the immune system recognize tumors. // “If these results are true, this represents the first proof of principle of a ...

Bellicum Pharmaceuticals Announces Initiation of Phase I/II Clinical Trial of Novel Vaccine for Patients With Advanced Prostate Cancer

...f BP-GMAX-CD1, a novel pharmacologically regulated dendritic cell vaccine for the treatment of prostate cancer....by genetically modifying autologous antigen-loaded dendritic cells to express an inducible costimulatory CD40 (...adermal administration, these genetically modified dendritic cells are activated in draining lymph nodes by int...

Scientists learn why even treated genital herpes sores boost the risk of HIV infection

...cientists found a significantly higher concentration of immune cells called dendritic cells with the surface protein called DC-SIGN at the sites of healed genita...n in control tissue, whether or not the patient was treated with acyclovir. dendritic cells with DC-SIGN ferry HIV particles to CD4+ T cells, which the virus inf...

Microscopic 'beads' could help create 'designer' immune cells that ignore transplanted organs

...ral suppressor of the immune response, straight to dendritic cells, which typically show the immune system what...ticles are given right after a transplant, just as dendritic cells are giving the immune system a heads up to g...ly would be needed for just a few weeks, until the dendritic cells have learned instead to ignore it, Dr. Horuz...

Study identifies biomarker that safely monitors tumor response to new brain cancer treatment

...considered a potential ally, but the brain has few dendritic cells -- key sentries of the immune system that de...i-tumor immune attack. Without the surveillance of dendritic cells, brain tumors go undetected and proliferate ...s (the immune stimulatory cytokine Flt3L) attracts dendritic cells from bone marrow into the tumor while anothe...

CEL-SCI Expands Testing of Its Vaccine to Determine Efficacy Against More Virulent Strain of H1N1 Swine and Other Influenza Viruses

...n specific antibody production in animal models. The concept behind the L.E.A.P.S. technology is to directly mimic cell/cell interactions on the dendritic and T-cell surface with synthetic peptides. The L.E.A.P.S. constructs containing the antigenic disease epitope linked to an Immune/T-cell binding liga...
Dendritic in Medical Technology

Study Demonstrates that AHCC(R) Enhances Immune System by Increasing the Production of Key Dendritic Cells

Proves significance of AHCC for maintaining a healthy immune system PURCHASE, N.Y., Jan. 6 /PRNewswire/ -- A recently published study in Nutrition and Cancer (60(5), 643-651) by researchers at Kansai Medical University in Osaka, Japan has shown that AHCC (Active Hexose Correlated Compound) ...

Study Shows Cancer Vaccines Led to Long-Term Survival for Patients with Metastatic Melanoma and to Long Periods of Disease Control After Completion of Therapy

...es. The study entitled "Phase II Trial of dendritic Cells Loaded with Antigens from Self-Renewing, Pro...r a total of up to eight injections. The patient's dendritic cells were obtained from their peripheral blood an... (64 vs. 31 months, p=.016). Eight patients in the dendritic cell vaccine study experienced remarkable long-ter...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

....S. vaccines can activate and cause human immature dendritic cells from blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell media...

Agennix Receives Fast Track Designation From FDA for Talactoferrin in Combination With Sunitinib for Renal Cell Carcinoma

...actoferrin Talactoferrin is a novel targeted dendritic cell recruiter and activator (DCRA) being studied ...rin mediates its anti-cancer activity by targeting dendritic cells which play an important role in activating i... talactoferrin induces the recruitment of immature dendritic cells to the GALT and promotes their maturation. ...

BioInformatics, LLC New Report - Capitalizing on New Opportunities for Stem Cell Products, Now Available

...f increasing interest over the next couple of years. By 2011, osteogenic cells in particular, but also endothelial, cardiomyocytes, chondrocytes, and dendritic cells are projected to be differentiated states as common as hematopoeitic and epithelial cells. These findings have implications for product developm...

Doctors Urge Precaution to Shield Against Swine Flu

...port NK cell activity in people with low NK cell function, improving the coordination of many aspects of immune response, including the interaction of dendritic macrophage cells, T-cells and B-cells, resulting in improved health. The benefit of AHCC's NK Cell supporting effect, and its role in defense ag...
Dendritic in Medical Definition

Thymocyte

... as classical T cells, a number of alternative cell lineages develop in the thymus, including gamma-delta T cells, Natural Killer T cells and lymphoid dendritic cells. References ^ Baldwin TA, Hogquist KA, Jameson SC, The fourth way? Harnessing aggressive tendencies in the thymus. “J Immunol....
Dendritic in Medical Dictionary

Keratitis

... Keratitis signs or ... Keratitis is an inflammation of the cornea, the transparent membrane that covers ... These infections are called dendritic keratitis and aid in the diagnosis. ... Keratitis (KEHR-ah-TI-tis) is an inflammation or irritation of the cornea, often ... There are many ...

Ebola

... occurring. ... The typical immune response to Ebola infection is characterized by an impaired ... Ebola virus infects and replicates in dendritic cells, monocytes, and ... Treatments for Ebola including drugs, prescription medications, alternative treatments, surgery, and lifestyle chang...
Dendritic in Biological News

Knowledge of dendritic cells branches out

A new type of cell that generates crucial cells of the immune system has been discovered at The Walter and Eliza Hall Institute. With this new knowledge, medical researchers can begin to consider the development of customized immune therapies using this new cell to target specific infections such a...

T cells activated to fight HIV basis for dendritic cell therapeutic vaccine

Having their immune system cells go through a laboratory version of boot camp may help patients win their battle against HIV, believe University of Pittsburgh researchers. In essence, that's the concept behind the development of a novel therapeutic vaccine loaded with a patient's own souped up dend...

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

...rapies. The study entitled "Phase II Trial of dendritic Cells Loaded with Antigens from Self-Renewing, Pro...r a total of up to eight injections. The patient's dendritic cells were obtained from their peripheral blood an... (64 vs. 31 months, p=.016). Eight patients in the dendritic cell vaccine study experienced remarkable long-ter...

DOE-funded research projects win 46 R&D 100 Awards for 2009

... enhanced data access capabilities beyond other equivalent operating systems by employing a new technique that targets memory bandwidth. NanoCoral dendritic Platinum Nanostructures - An innovative nanotechnology for producing platinum catalysts that offers unique control over the shape, size, porosity, com...

Building memories with actin

...more potent after repeated stimulation, underlies the formation and stabilization of new memories. LTP involves changes in the anatomy of synapses and dendritic spines, a process that depends on reorganization of the supporting actin cytoskeleton. However, researchers didn't know what controlled these changes....

Protein linked to mental retardation controls synapse maturation, plasticity, CSHL team finds

...ronal structure. Small knob-like features, called dendritic spines, that protrude from a neuron's branch-like ...ling protein is not essential for the formation of dendritic spines, but that it is needed for the proper maint...synapse, the team found that OPHN1 is recruited to dendritic spines, where it locally regulates the actin cytos...
Dendritic in Biological Technology

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

Technology also has potential to fight cancer, rheumatoid arthritis, as well as enhance the effectiveness of vaccines VIENNA, Va., April 27 /PRNewswire-FirstCall/ -- CEL-SCI Corporation (NYSE Amex: CVM ) announced today the presentation of data at the 11th annual National Foundation of Infe...

MaxCyte and Medinet to Present at the 10th International Symposium on Dendritic Cells in Kobe, Japan

"Tumor lysate electroloaded mature human DC exhibit enhanced antigen-specific potency compared to lysate co-incubation in clinical manufacturing scale" GAITHERSBURG, Md. and YOKOHAMA, Japan, Oct. 2 /PRNewswire/ -- MaxCyte, Inc. and Medinet Co., Ltd. (TSE: #2370) announce a joint poster prese...

Oncolytics Biotech Inc. Announces Journal of Immunology Publication on Reovirus Activation of Dendritic Cells

CALGARY, April 23 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ:ONCY) announced today that Prof. Alan Melcher and his research group at St. James's University Hospital in Leeds, U.K. published the results of their work with reovirus in the May 1, 2008 online ...

Northwest Biotherapeutics Announces Plans to De-list From AIM and Consolidate its Stock Market Listing in U.S.

...reat cancers more effectively than current treatments, without toxicity, on a cost-effective basis. The Company has two broad platform technologies: dendritic cell-based vaccines and therapeutic antibodies. The Company is in a large Phase II clinical trial in GBM, with 13 clinical sites across the U.S. The ...

Santaris Pharma - Interim Report for the Period 1 January to 30 June 2009

...academic partners published an article titled: A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. BMC Med Genomics In June 2009 Santaris Pharma and academic partners published an article titled: Identification and...

Significant Milestone Marks the Beginning of FDA-Authorized Breast Cancer Trial

...n its breast cancer trial has begun to receive its dendritic cell therapy. QI is currently sponsorin...." The clinical trials involve the use of dendritic cell therapy using the oncofetal antigen ("OFA"), ...ial is designed around the use of QI's proprietary dendritic cell therapy, which employs OFA to recruit the pat...
Dendritic in Biological Products

UCB MoDC Cell Chip-IHC from 3H Biomedical AB

Description:... Monocyte-derived dendritic cells, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood dendritic Cells...
Company:3H Biomedical AB

PDC Cell Chip-IHC from 3H Biomedical AB

Description:... Human plasmacytoid dendritic cells, BDCA-4+, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood dendritic Cells and EPCs...
Company:3H Biomedical AB

EPC Cell Chip-IHC from 3H Biomedical AB

Description:... Human endothelial progenitor cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood dendritic Cells and EPCs...
Company:3H Biomedical AB

UCB PDC Cell Chip-IHC from 3H Biomedical AB

Description:... Plasmacytoid dendritic cells, BDCA-4+, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood dendritic Cells...
Company:3H Biomedical AB

MoDC Cell Chip-IHC from 3H Biomedical AB

Description:... Human monocyte-derived dendritic cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood dendritic Cells and EPCs...
Company:3H Biomedical AB

Mouse Anti-Human DEP-1 / CD148 Monoclonal Antibody, Fluorescein Conjugated, Clone 143-41 from R&D Systems

Description:... Human DEP-1/CD148 Fluorescein MAb (Clone 143-41) Protein Family: Granulocyte Markers, Monocyte Markers, Phosphatases & Regulators, Other dendritic Cell Molecules...
Company:R&D Systems
Dendritic in Biological Definition

Apoptosis

..., and published in Science Online in December, 2001. Albert described how dendritic Cells, a type of antigen-presenting cells, phagocytose (that is, engulf) apoptotic tumor cells. Upon maturation, these dendritic cells present antigen (derived from the apoptotic corpses) to killer T cell...

Dendrite

...ts from separate branches or "arbors." The term "dendrite" comes from the Greek word dendron , meaning "tree". Compare : axon See also : dendritic spine ...

Immune system

... cells (APCs). A major category of APCs involved in T cell activation, the dendritic cells , are part of the innate immune system. Activation occurs when a DC s...n by T cells that are all belonging to the adaptive immune system. But the dendritic cells are often directly activated by engaging their toll like receptors ...

Major histocompatibility complex

...ents a risk of contagion for neighboring cells. Mhc Class II molecules are found only on a few specialized cell types, including macrophages , dendritic cells , activated T cells , and B cells , which may be referred to collectively as "antigen-presenting cells" (APCs). Class II molecules are also ...

Neuron

...munication with many target cells. The dendrite , a short, branching arbor of cellular extensions. Each neuron has very many dendrites with profuse dendritic branches. These structures form the main information receiving network for the neuron. Axon and dendrites alike are typically only about a microm...

Synapse

...4 Integration of synaptic inputs 5 Detailed properties and regulation 6 References Anatomy At a prototypical synapse, such as a dendritic spine , a mushroom-shaped bud projects from each of two cells and the caps of these buds press flat against one another. At this interface, the mem...
Dendritic in Biological Dictionary

Purkinje fibers

... cells have two action potentials: Climbing fiber responses (CFRs) and ... action of a subset of parallel fiber synapses on Purkinje cell dendritic spines. ... ...

Protocells

...ed thermal proteins ... attributes of life), and metaprotocells ( protocells that can use light to ... Photographs of Protocells . Formation of dendritic and free protocells on the surface of abiotic thermal ... Protocells are 3 um in diameter. ... Shop for Protocells - Books at Shop.com. Books...

Monocytes

...d cell, part of the human body's immune system. Monocytes have two main functions in the immune system: (1) replenish resident macrophages and dendritic cells under normal states, and (2) in... Monocytes develop in the bone marrow and reach maturity in the blood. ... Monocytes ingest fore...

Immunology

...k's classic features ... Nature Immunology is a multidisciplinary journal that publishes papers of the ... Postdoctoral Position- Immunology of dendritic Cells ... Monthly review journal publishes peer-reviewed articles on immunology , including infection and immunity. PART ONE: IMMUNOLOGY . Im...

Dendritic cell

... 4 dendritic cells and cytokines. 5 Relationship to HIV, allergy, and autoimmune diseases ... Plasmacytoid dendritic cell (pDC) ... Dendrites are the branched...es project. Electrical... The key function of dendritic cells is that of "presenting of antigen": bindi...

Dendrites

... ... Although the brain's axons and dendrites are neighbors, they differ in many ... abnormally short dendrites , so Jan's group named the genes dendritic arbor ... ...
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