Delivery

New methods of gene delivery using lasers

Leading laser scientists at the University of St Andrews have developed a new method of delivering genes to cells using laser light. The new technique, which is cheap and powerful, could have important implications for future studies in biomedicine and healthcare. Optical technology has huge potential for novel developments in the bio-medical field and St Andrews has outstanding research...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

Transferrin, a plasma protein found in blood, can be fused with large, protein-based drugs such as granulocyte colony-stimulating factor (G-CSF) to create a new oral compound that is capable of surviving the journey through the gastrointestinal (GI) tract and then able to cross over into the bloodstream to be used by the body, according to research from the University of Southern California Schoo...

Self-assembled DNA buckyballs for drug delivery

DNA isn't just for storing genetic codes any more. Since DNA can polymerize -- linking many molecules together into larger structures -- scientists have been using it as a nanoscale building material, constructing geometric shapes and even working mechanical devices. Now Cornell University researchers have made DNA buckyballs -- tiny geodesic spheres that could be used for drug delivery an...

“Hitchhiking?Viruses as Cancer Drug Delivery System

About five to seven million years ago, when the lineage of humans and chimpanzees split, edible root plants similar to rutabagas and turnips may have been one of the reasons. According to research by anthropologists Greg Laden of the University of Minnesota and Richard Wrangham of Harvard University, the presence of fleshy underground storage organs like roots and tubers must have sustained our a...

'Cookbook recipes' would cure disease with nontoxic DNA delivery systems

Scientists studying the structure and interaction of negatively charged lipids and DNA molecules have created a "cookbook" for a class of nontoxic DNA delivery systems that will assist doctors and clinicians in the safe and effective delivery of genetic medicine. As reported in the Aug. 9 issue of the Proceedings of the National Academy of Sciences, researchers have now performed a careful...

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Delivery at Biology Products

PULSin Protein & Antibody Delivery Reagent from Polyplus Transfection

Description:PULSin is an innovative reagent for highly efficient transfer of functional proteins to the cytoplasm of living cells. Unlike DNA transfection, with PULSin Protein & Antibody Delivery Reagent the amount and timing of exogenous proteins in cells can be controlled, even lethal proteins can now be studied. Real time function blocking and protein localization studies can now be easily performed u...
Company:Polyplus Transfection

PULSin Protein & Antibody Delivery Reagent from Polyplus Transfection

Description:Protein/antibody delivery using PULSin may be superior to transfection in some applications. For example, unlike traditional transfection, with PULSin you can study lethal proteins and control the level and time course of proteins in cells. Likewise, delivery of blocking antibodies may provide more information than traditional RNA interference experiments. With PULSin you can target in...
Company:Polyplus Transfection

PULSin Protein & Antibody Delivery Reagent from Polyplus Transfection

Description:Protein/antibody delivery using PULSin may be superior to transfection in some applications. For example, unlike traditional transfection, with PULSin you can study lethal proteins and control the level and time course of proteins in cells. Likewise, delivery of blocking antibodies may provide more information than traditional RNA interference experiments. With PULSin you can target in...
Company:Polyplus Transfection

Delivery at Biology Technology

pFB-ERV: Retroviral Delivery of the Ecdysone Receptor Proteins

Faster, easier screening for difficult transfections when using thecomplete control kit Stratagene We describe the vector pFB-ERV, an MMLV-based replication-defectiveretroviral vector for delivery of the ecdysone receptor proteins RXR and VgEcR.In stable cell lines infected with an estima...

High-Titer Retroviral Vectors for Gene Delivery

High-TiterRetroviral Vectors for Gene Delivery Stratagene The high-titer retroviral vectors pFB and pFB-Neo can be used with anyMoloney Murine L...

Effectene Transfection Reagent provides efficient gene delivery to primary neuronal cell cultures

Jochen Meier, Ivonne Strmel, Radu Iosub, Sonja Schmidt, and Rosemarie Grantyn Developmental Physiology, Johannes Mller Institute, Humboldt University Medical School (Charit), Berlin, Germany Efficient delivery of DNA to primary neuronal cell cultures is of critical importance...

UW professors get grants to engage technology for course delivery

Cramer, professor Hussain Bahia, program assistant Carole Kraak and staff from Engineering M...

A New Way to Assess siRNA Delivery Efficiency

Assess GAPDH siRNA delivery in less time for a fraction of the cost of real-time PCR Measure both GAPDH siRNA-induced knockdown AND transfection-induced toxicity Use with Silencer GAPDH siRNA Controls and Silencer CellReady Transfecti...

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Delivery at Medicine News

Laboratory Testing Can Identify Risk of Pre-Term Labor and Delivery

A test for fetal fibronectin can predict whether a pregnant woman is at risk for early labor and delivery. Those at high risk for pre-term births are women with previous pre-term deliveries, those with multiple gestation pregnancy, and those who suffer from diabetes and/or hypertension. The current approach for finding whether a woman will go into premature labor is the use of a clinical scoring...

Early delivery can prevent cancer

Scientists have found out why women who have a baby when they are relatively young have a lower risk of developing breast cancer. They have identified a substance produced naturally in the body that protects against the disease. Hormones released during pregnancy trigger the changes in the breast tissue of young women. The research raises the possibility of one day developing a pill that could pr...

Link between C-section Delivery and Stillbirth

A new study shows women who undergo a cesarean section during their first pregnancy are at an increased risk of having a stillborn child down the road.// Researchers are uncertain why the link between C-section delivery and stillbirth exists but say it could be a biological cause. Researchers in Scotland studied data for all second births that took place in the country betwe...

Painkilling Patch As Effective As Intravenous Delivery Systems

Findings from a recent study has shown that an adhesive patch that resembles the size of a credit card and uses a tiny electric current to deliver pain medication through the skin does the job about as well as conventional intravenous devices. // The patch is affixed to the patient's upper arm or chest after surgery. Both the patch and some intravenous delivery systems allow the patient to self-m...

The Effects Of Delaying A Delivery Questioned

How early does a child have to be born if it starts to have complications in utero , is a question many obstetricians would answer differently.// A new study done in this area may shed some light on the benefits of delaying the birth. The study finds even a small delay could reduce the risk of a disability for the baby. Until now, no study has ever compared the effect of delaying a deliv...

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Delivery at Medicine Products

Topcon IDS-200 Instrument Delivery System

Description:This exciting new product has generated lots of interest, and continues to be one of the most efficient instruments in Ophthalmology and Optometry today. Time Saving benefits any practice. This system can present the auto refractor values directly to the patient. The ultimate in space efficiencyfits comfortably in a 7' X 7' examination room without the need for external projection mirrors....
Company:Topcon America Corporation

Monarch II IOL Delivery System

Description:Lens Loading and Folding for Multipiece & Single-Piece ACRYSOF Lens with Standard Forceps...
Company:Alcon Laboratories

Attain™ Deflectable Catheter Delivery System

Description:The Attain™ Deflectable Catheter - designed to be your best option for cannulation using a single catheter. Steerablility - Create a variety of curve shapes during the procedure with a single, steerable guide catheter. Lock the easy-to-use handle mechanism in the desired shape to address each patient's unique anatomy during CS cannulation. Stable, Versatile Workstation. Inject contrast thro...
Company:Medtronic Inc.

Attain Left Heart Delivery System

Description:Attain Left-heart Lead Delivery Systems. Medtronic offers left-heart lead delivery systems to assist with accessing the coronary sinus (cs)....
Company:Medtronic Inc.

Attain Prevail™ Steerable Catheter Left-Heart Lead Delivery System

Description:Steerability - Use the Attain Prevail's steerable tip, along with various fixed-shape guide catheters and guide wires, to obtain the curve you need, when you need it. Inject contrast media for improved visualization of the cardiac venous anatomy, adjust course as needed with tip deflection. Telescoping - Adjust curve and reach by telescoping the Attain Prevail through a straight or fixedshape gu...
Company:Medtronic Inc.

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Delivery at Medicine Technology

Pieris Progresses Proprietary Asthma Program: Validation of Pulmonary Delivery of Anticalin-Based Protein Product Candidate

FREISING-WEIHENSTEPHAN, Germany, July 10, 2007 /PRNewswire/ --Pieris AG, a bio-pharmaceutical company developing Anticalins(R), anovel class of targeted human protein therapeutics, today announcedsignificant progress in validating novel, effective products forthe potential treatment of asthma. In studies of its proprietaryPRS-060 Anticalin(R) candidate, the Company reports that theprotei...

TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment

LOD, Israel--(BUSINESS WIRE)--Jul 9, 2007 - TransPharma MedicalLtd., a specialty pharmaceutical company focused on the developmentand commercialization of drug products utilizing a proprietaryactive transdermal drug delivery technology, announced todaypromising results of its phase I clinical trials demonstrating thesafety and pharmacokinetic profile of its ViaDerm-hPTH (1-34)product for th...

Phosphagenics Announces Positive Proof of Concept Results from Studies Utilizing Company's Dermal Drug Delivery Technology

MELBOURNE, Australia, June 25, 2007 /PRNewswire-FirstCall/ --Phosphagenics Limited (AIM: PSG) announced today positive resultsfrom pre-clinical studies of its TPM-02 dermal drug deliverytechnology formulated with retinoic acid, a leading topicaltreatment for severe acne and an active ingredient used inanti-aging cosmetics. The proof of concept studies showed a three-fold increase i...

Next Safety, Inc.'s Innovative Drug Delivery System Will Replace Cigarettes and Significantly Advance Pulmonary Medication Delivery

WEST JEFFERSON, N.C.--(BUSINESS WIRE)--Jun 15, 2007 - Next Safety,Inc. has identified basic scientific mechanisms that promise torevolutionize pulmonary drug delivery. This proprietary technologyuses a stream of purified air to deliver medications deep into thepulmonary system. It is considered superior to other drug deliverysystems because it rapidly administers aerosolized drugs to thelin...

PARI Pharma Presents Study Results of Sinus Delivery and Inhaled Liposomal Ciclosporin A at European Cystic Fibrosis Conference

MUNICH, Germany, June 14, 2007 /PRNewswire/ -- PARI Pharma willpresent in-vivo study results for their PARI SINUS pulsating drugdelivery system as well as lung deposition and pharmacokinetic dataof their proprietary inhaled liposomal Ciclosporin A formulation inlung transplant patients at the European Cystic Fibrosis Conference(ECFC) in Belek, Turkey this week. Continuing their tra...

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