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Degranulation in Medical News

Innate immune system targets asthma-linked fungus for destruction

...g constantly activated to recruit eosinophils and this sustained defense mechanism results in chronic inflammation. It has been shown previously that degranulation of eosinophils causes damage of airway mucosa and enhances inflammation. The next step in our transdisciplinary research collaboration will be to use ...
Degranulation in Biological Products

Mast Cell Degranulation colorimetric Assay Kit from CHEMICON

Description: Degranulation, the secretion of cytoplasmic granules, is a key step in the inflammatory response of leukocytes (e.g. basophils, neutrophils, eosinophils, and mast cells). In addition to histamine, these secretory granules contain many proinflammatory mediators including heparin, cytokines, chemokin...
Company:CHEMICON

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...TE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the mitogen-activated protein kinase (MAPK) pathway in stimulated neutrophils....
Company:Cayman Chemical

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...TE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the mitogen-activated protein kinase (MAPK) pathway in stimulated neutrophils....
Company:Cayman Chemical

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...TE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the mitogen-activated protein kinase (MAPK) pathway in stimulated neutrophils....
Company:Cayman Chemical
Degranulation in Biological Definition

Antibody

...ent proteins. In this way it mediates different physiological effects of antibodies ( opsonization , cell lysis , mast cell, basophil and eosinophil degranulation and other processes). The variable regions of the heavy and light chains can be fused together to form a single chain variable fragment (scFv), wh...
Degranulation in Biological Dictionary

Effector cell

... B release ... The effector cells are triggered when their antigen specific receptors and ... The number of effector cells expressing the degranulation associated ... and ability to estimate cytotoxic effector cell frequency, the GrB ELISPOT assay ... Antigenic stimulation down-regulates CCR7 o...
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