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Degraded in Medical News

Groups to Congress: Don't Sacrifice Patient Safety to Lower Health Costs

...es. State malpractice damage caps, and other limits on liability for negligent health care providers, have locked injured patients out of court, degraded the quality of health care and denied justice to too many families, said Consumer Watchdog. "Those who wish to reduce the costs of medical malpra...

Nurses Decry 'Cruel Ruse' of GOP Health Plan

... Patient Care Will be degraded by End of Health Coverage OAKLAND, Calif., June 18 /PRNewswire/ -- Geri Jenkins, RN, co-President of the National Nurses Organizing Committee/Cal...

Woman Whose Health Insurance Was Cancelled by Blue Cross/WellPoint After She Got Sick Urges Congress to Protect Innocent Patients

...ow-benefit policies. Such policies will certainly have skimpier benefits, high deductibles, and high co-pays. For a patient like Ms. Horton, such a degraded policy is almost as effective in blocking access to care as canceling coverage. "The health insurance industry is promising to provide insurance...

4-in-1

...mRNA. Inside the cell, a special protein complex binds to the siRNA, which unwinds and cleaves the mRNA. In this unprotected form, the mRNA is rapidly degraded by the cell. When bound to nanoparticles, the siRNAs are easier to slip into cells. In order to specifically target cancer cells, the particles car...

International team cracks mammalian gene control code

...s long, 100 times smaller than an average gene. "Researchers had previously noticed small lengths of RNA in the genome, but thought that they were degraded segments of larger genetic elements," Mr Taft said. "We found that they were too common and too specifically distributed to be rubbish. They are w...

Cat Food-Linked Illness Yields Clues to MS

...March 30 issue of Proceedings of the National Academy of Sciences , would suggest that people with MS and similar nerve disorders in which myelin has degraded -- but the nerves are still functioning -- might benefit from treatment aimed at rebuilding the fatty substance. Loss of the myelin covering on a...
Degraded in Medical Technology

Cequent Pharmaceuticals' Johannes Fruehauf, MD, Ph.D., to be Featured Speaker at RNAi World Congress in Boston - May 2, 2008

...a to produce and deposit mediators of RNA interference (short hairpin RNA) directly into the target cells. The nonpathogenic bacteria are subsequently degraded by the host cells without adverse effects, and eliminated by the body through its own natural processes. This method has been shown to induce targeted...

Versatility of 454 Sequencing(TM) Demonstrated in Three Publications in Science Last Week

...rch," explained Michael Egholm, Ph.D., vice president of research and development at 454 Life Sciences. "Researchers were able to sequence ancient and degraded DNA, obtain a paired-end map of structural variation throughput the human genome at unprecedented resolution, and analyze the role of gene expression ...
Degraded in Medical Products

MM-PTH RIA Test

Description:...y the kidney. Following release into the circulation, intact PTH is rapidly degraded into 4 fragments: N-terminal (residues 1-34), C-terminal (residues 35-84) a...he N-terminal fragment retains full biological potency, and is also rapidly degraded in the blood. The biologically inactive C-terminal and mid-molecule fragmen...
Company:Diagnostic Systems Laboratories, Inc.

C-PTH RIA Test

Description:...y the kidney. Following release into the circulation, intact PTH is rapidly degraded into 4 fragments: N-terminal (residues 1-34), C-terminal (residues 35-84) a...he N-terminal fragment retains full biological potency, and is also rapidly degraded in the blood. The biologically inactive C-terminal and mid-molecule fragmen...
Company:Diagnostic Systems Laboratories, Inc.

I-PTH IRMA Test

Description:...y the kidney. Following release into the circulation, intact PTH is rapidly degraded into 4 fragments: N-terminal (residues 1-34), C-terminal (residues 35-84) a...he N-terminal fragment retains full biological potency, and is also rapidly degraded in the blood. The biologically inactive C-terminal and mid-molecule fragmen...
Company:Diagnostic Systems Laboratories, Inc.

I-PTH ELISA Test

Description:...y the kidney. Following release into the circulation, intact PTH is rapidly degraded into 4 fragments: N-terminal (residues 1-34), C-terminal (residues 35-84) a...he N-terminal fragment retains full biological potency, and is also rapidly degraded in the blood. The biologically inactive C-terminal and mid-molecule fragmen...
Company:Diagnostic Systems Laboratories, Inc.

Angiotensin II RIA Hypertension / Cardiac Evaluation, Cardiovascular 001-RK-A22

Description:..., lung and other tissues, into Ang II, the major active component of the renin-angiotensin cascade10, 11 (see fig.1). This octapeptide is then rapidly degraded by various angiotensinases (aminopeptidases) found in plasma and tissues to the heptapeptide Ang III and to its subsequent degradation products, the h...
Company:ALPCO Diagnostics
Degraded in Medical Dictionary

Ossicle

...the medial epicondyle. ... ... stapes, known together as the ossicle chain, and is where conductive hearing ... intent of replacing severely degraded or absent components of the ossicle chain. ... small ossicle at the radioulnar articulation ... Along the ulnar aspect of the styloid process,...

Kinins

... Kinins are vasodilatory peptides liberated from the protein precursor, kininogen, ... Under physiological conditions, endogenous kinins are degraded into inactive ... Aprotinin or the kinin antagonist produced no consistent change in renal ... These studies provide evidence that kinins ge...
Degraded in Biological News

Dinosaur DNA? New Patent Covers Degraded DNA recovery

The US Patent Office issued Patent # 6,872,552, "A Method of Reconstituting Nucleic Acid Molecules" today to Burt D. Ensley, Ph.D, Chairman of MatrixDesign, and CEO of DermaPlus, Inc. The patent covers methods for recovering and reconstituting genes from "degraded" DNA samples, and could allow scie...

Hormone clue to root growth

...ne of cell proliferation. Plants in which the cells in the meristem were made to express a mutant version of the growth-repressing protein GAI not degraded by gibberellin showed disrupted cell proliferation. Expressing this mutant form, gai, in only one tissue, the endodermis (the innermost layer of the r...

Nitrogen research shows how some plants invade, take over others

...ne is a successful invader. Knops said he was somewhat surprised by the pines' ability to pull so much nitrogen out of the soil, especially in the degraded old fields that were studied. Knowing this finding about nitrogen cycling with the white pine species may lead to important discoveries in how to s...

Nursery programs for corals receive TLC from NOAA this Independence Day

...ditional nurseries in the Dry Tortugas and the USVI. In all, the project will grow roughly 12,000 corals in Florida to enhance coral populations at 34 degraded reefs in the region. Lirman, in UM's Marine Biology and Fisheries division, established a staghorn coral nursery within Biscayne National Park in ...

Corals stay close to home

...l populations comes from other locally sourced coral, one cannot depend on genetic material from distant populations of corals to replenish or restore degraded local populations. In these regions, marine reserves that maintain high local genetic diversity should be favoured. ...

Coral face 'a stormy future'

...hese important species appear not to have recruited at all. "Healthy reefs usually have high numbers of coral recruits and juvenile corals, whereas degraded systems typically have far fewer young colonies." The concern is that if major storms and bleaching become more frequent as the climate warms, the ...
Degraded in Biological Technology

Sigma-Aldrich Releases WTA2, a Transplex Whole Transcriptome Amplification Technology for Degraded RNA Samples

WTA2 Kits Offer Rapid, Robust Amplification of Partially Degraded RNA ST. LOUIS, Oct. 28 /PRNewswire-FirstCall/ -- Sigma-Aldrich (Nasdaq: SIAL) today announced the launch of its TransPlex(R) Whole Transcriptome Amplification (WTA2) technology ( http://www.sigma.com/wta ). TransPlex technology...

DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology

...ive drugs that can be delivered orally with the LPM(TM) system include various classes of drugs such as peptides, nucleic acids and proteins which are degraded in the stomach and small intestine. Corresponding patents in the United States and elsewhere are currently pending. About DOR BioPharma, Inc. ...

PolyOrg, Inc. Acquires a License to Manufacture and Distribute PNA Monomers Worldwide

..., and Dr. Rolf H. Berg (Copenhagen Inventor Group) PNAs hybridize strongly and sequence-specifically to complementary DNA or RNA. They however are not degraded by nucleases or proteases. These properties of PNA have made them extremely attractive for applications in molecular biology, diagnostics, as well as ...

Novel Mass Spectrometry-based Assay Reveals Degradation and Low Levels of Bioactive B-type Natriuretic Peptide (BNP) in Patients with Heart Failure

...ncentration of bioactive BNP in plasma obtained from patients with heart failure, and presented direct structural evidence for several proteolytically degraded forms of BNP in these patients. "Commercially available assays for immunoreactive BNP do not reflect the bioactivity of the natriuretic peptide syst...

Oil palm plantations are no substitute for tropical rainforests, a new study shows

...recorded in primary forest were found in oil palm. degraded forest, and even alternative crops such as rubber ...s, there needs to be a careful distinction between degraded land that is of low conservation value, such as imperata grasslands, and partially logged or degraded forest areas which can still harbour relatively hi...

Comprehensive Jatropha Standards Mandatory in Optimum Long-term Biofuel Efficacy

...o-Energy Certification Jatropha for Rural Development Scaling up Rural Community Projects for Commercial Value Jatropha for Rehabilitation of degraded Lands Expert panelists for the conference will include individuals from the International Crops Research Institute for Semi-Arid Tropics (ICRISAT),...
Degraded in Biological Products

Amylase Fluorometric (Green) Assay Kit, EnzChek® from Molecular Probes (Invitrogen)

Description:... DQ starch substrate that is labeled with BODIPY FL dye (Figure 1) to such a degree that the fluorescence is quenched. This substrate is efficiently degraded by amylase; digestion relieves the quenching and yields highly fluorescent fragments. The accompanying increase in fluorescence is proportional to amy...
Company:Molecular Probes (Invitrogen)

m7G(5)ppp(5)G (Cap Analog) from Ambion

Description:... Capped mRNAs are generally translated more efficiently in reticulocyte lysate and wheat germ in vitro translation systems. Uncapped mRNAs are rapidly degraded after microinjection into cells. Thus, it is important to cap in vitro transcripts for microinjection experiments. Cap analog is also used as a highly...
Company:Ambion

m7G(5)ppp(5)G (Cap Analog) from Ambion

Description:... Capped mRNAs are generally translated more efficiently in reticulocyte lysate and wheat germ in vitro translation systems. Uncapped mRNAs are rapidly degraded after microinjection into cells. Thus, it is important to cap in vitro transcripts for microinjection experiments. Cap analog is also used as a highly...
Company:Ambion

Ubiquitin Fraction I Extract from GeneTex

Description:...nscription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum. The 26S proteasome is an ATP-dependent, multisubunit (~31...
Company:GeneTex

IRS Extract from GeneTex

Description:...nscription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum. The 26S proteasome is an ATP-dependent, multisubunit (~31...
Company:GeneTex

26S Proteasome Fraction Extract from GeneTex

Description:...nscription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum. The 26S proteasome is an ATP-dependent, multisubunit (~31...
Company:GeneTex
Degraded in Biological Definition

Antigen

... by inhalation, ingestion, or injection. These antigens are taken up by endocytosis or phagocytosis into the antigen presenting cells (APCs), and degraded into fragments. The fragments are then presented on the surface of APCs by class II histocompatibility molecules to T helper cells (CD4 + ). Those ...

Blood

...ic waste products, drugs and other foreign chemicals to the liver to be degraded and to the kidney to be excreted in urine . A buffer solution of ca...watery fraction maintained by the gut and the kidney . Blood cells are degraded by the spleen and the Kuppfer cells in the liver. The liver also clears...

Cell biology

...ir respective compartments. Other proteins "flow" through the ER and Golgi to the plasma membrane. From the plasma membrane, proteins destined to be degraded move back into intracellular compartments where they are broken down to their individual amino acids . Techniques Purification ...

Cloning

...[3] . However, on February 15 2005 the museum announced that it was stopping the project after tests showed the specimens' DNA had been too badly degraded by the ( ethanol ) preservative. One of the continuing obstacles in the attempt to clone extinct species is the need for nearly perfect DNA. Furthe...

Diabetes mellitus

... by way of gluconeogenesis and glycogenolysis . Fat in adipose tissue is reduced to triglycerides and fatty acids by lipolysis . Muscle is degraded to release amino acids for gluconeogenesis. The rise of fatty acid levels is accompanied by a rise of ketones ( acetone , acetoacetate and beta-...

Immune system

...of the presence of the second enzyme. However, when a bacteriophage attempts to infect this bacterium, the viral DNA has not been protected, and gets degraded by the first enzyme. While study of the bacterial immune system provides useful insights into immunology, the remainder of this article will focus on ...
Degraded in Biological Dictionary

Western blotting

... protein on acrylamide; or DNA/RNA on agarose. ... Western blotting tells you how much protein has accumulated in cells. ... a protein is degraded quickly, Western blotting won't detect it well; you'll need to ... Pall Corporation manufactures Western blotting membranes made from ......

Western blot

...r to use the term western blot . Burnette WN. ... Western blotting tells you how much protein has accumulated in cells. ... a protein is degraded quickly, Western blotting won't detect it well; you'll need to ... Pall Corporation manufactures Western blotting membranes made from ......

Pyrimidine

...e Nucleotides ... The purine and pyrimidine bases released are either degraded or salvaged for ... Pyrimidine is a heterocyclic aromatic organic com...TP occurs in the cytoplasm and starts ... While pyrimidine rings can be degraded completely to CO2 and NH3 (urea excretion) ... GO:0019856 : pyrimidine ...

Polytene

..... Polytene chromosomes in the Drosophila salivary glands have distinctive banding patterns. ... Subsequently polytene chromosomes become degraded (stage a3) and a DNA ... During polytene chromosome degradation the 30 nm chromatin loops are released ... 1: Chromosome Res. 1997 Nov;5(7):4...

Mitochondrial DNA

... DNA -based technologies have enormous forensic implications in the fight against crime. Mitochondrial DNA MtDNA is perfect for older, smaller or degraded samples. Mitochondrial DNA (mtDNA) analysis allows forensic laboratories to develop DNA ... See Mitochondrial DNA Research Projects and J...

Macronucleus

...er, with some ... The macronucleus is highly polyploid (~800n in P. tetraurelia), divides ... During sexual events, the old macronucleus is degraded and replaced by a new one, ... Each cell contains a germ line micronucleus and a somatic macronucleus . ... All endogenous RPB3 genes in t...
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