Defect

Genetic defects give the immune system the green light to attack the pancreas

Scientists at Joslin Diabetes Center have found genetic regions that, when defective, allow the immune system to attack the pancreas ?the first in a series of mis-steps that lead to type 1 diabetes. Armed with these findings published March 22 in the journal Immunity, the researchers are now trying to hone in on the exact genes involved, in mice and in human patients. “The significance of...

Cellular Defects in Premature Aging Disease are Reversible

Cells affected by Hutchinson-Gilford Progeria Syndrome (HGPS) -- a disease associated with premature aging -- can be made healthy again, according to findings by scientists at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). Using specially modified segments of DNA, NCI researchers Paola Scaffidi, PhD, and Tom Misteli, PhD, reversed the abnormalities seen in H...

One hit of crystal meth causes birth defects

A single prenatal dose of methamphetamine ?commonly known as speed ?may be enough to cause long-term neurodevelopmental problems in babies, say University of Toronto researchers. In research published in the August issue of Free Radical Biology and Medicine, U of T pharmacy and pharmacology professor Peter Wells and his colleagues determined that exposing pregnant mice only once to methamp...

Montreal researchers identify defects of immune cells

Researchers at Université de Montréal and the Institut de recherches cliniques de Montréal (IRCM) have successfully identified a defective immune cell population that determines susceptibility to candidiasis, a common and often debilitating infection in individuals infected with the human immunodeficiency virus (HIV). These findings, revealed using a model of candidiasis in transgenic mice expres...

Micro-molecule plays big role in birth defects

University of Florida researchers have learned how to selectively shut down a flyweight-sized genetic molecule that packs a heavyweight punch, a discovery that may help doctors better understand cancer, birth defects and other health problems. The finding, which will be reported this week in the online Proceedings of the National Academy of Sciences, deals with tiny strands of genetic mate...

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CDC reveals relationship between prepregnant weight and heart defects in infants

Keeping fit and in to be in shape is not only good for the individuals themselves but also for their siblings. Over weight, which is of course the predisposer of majority of the illness such as diabetes, heart disease, hypertension etc., is now being studied in depth, the reason is to attain the destination of disease free environment, that are preventable.// Researchers from the US Cent...

IVF technique May Increase The Risk Of Birth Defects

The commonly used in vitro fertilisation (IVF) technique intracytoplasmic sperm injection (ICSI) may increase the risk of babies being born with abnormalities such as ambiguous genitalia. Researchers from the Pasteur Institute in Paris, France, say that men whose infertility is genetic are likely to have other, more serious genetic faults that can be passed on when spermatozoa are injected direct...

Epilepsy Drugs Can Enhance Risk of Birth Defects

Epilepsy is a chronic neurological disorder in which misfiring electrical impulses in the brain lead to seizures. About 2.3 million Americans have epilepsy, and more than a million are female. //Pregnant women who take anti-epileptic medications face a significant risk that their children will have problems ranging from congenital defects to slow development. A new study adds to growin...

Sex timing has no impact on risk of Birth defects

Researchers have found no bond between when a couple has sex and any subsequent risk of birth defects such as Down syndrome. Animal studies have suggested that the timing of sex might increase the risk of birth defects in offspring.// Dr. Joe Leigh Simpson, a professor of obstetrics and gynecology at Baylor College of Medicine in Houston told the press that they haven't yet confirmed o...

Defective heart valve causes problems

According to researchers, a recent study shows that a leaky heart valve raises the risk of abnormal heart rhythms. In atrial fibrillation (AF) the upper chambers of the heart beat randomly and unsuccessfully. The condition is linked to heart attack and stroke.// Researchers at the University of Texas, have now shown that having a leaky heart valve - separating the upper and lower heart chambers...

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CARDIA Atrial Septal Defect Closure Device

Description:The CARDIA ASD Occluder has been developed for the transvenous closure of atrial septal defects. Introduced through transseptal venous sheaths the device offers a safe and reliable method for the percutaneous closure of ASD's with a super low profile.A self centering mechanism is incorporated into the twelve arm device for optimal positioning and stability in the ASD.An integral locki...
Company:CARDIA, Inc.

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Birth Defects

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