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Decoy in Medical News

Fruit fly protein acts as decoy to capture tumor growth factors, find Penn researchers

PHILADELPHIA -- Researchers at the University of Pennsylvania School of Medicine have shown how Argos, a fruit fly protein, acts as a decoy' receptor, binding growth factors that promote the progression of cancer. Knowing how Argos neutralizes tumor growth may lead to new drug designs for inhibiti...

Scientists identify lab-made proteins that neutralize multiple strains of seasonal and pandemic flu

...lutinin protein to which humans rarely make antibodies," says Dr. Marasco. "We believe this is because the head of the hemagglutinin protein acts as a decoy by constantly undergoing mutation and thereby attracting the immune system to produce antibodies against it rather than against the pocket in the neck...

Manipulating Key Protein May Prevent Eczema

...ard Medical School. Geha and his colleagues found that even mice with IL-21 receptors could be spared from developing eczema by pumping them with a decoy receptor to fool their immune system and keep it from attacking the inflamed area. The finding offers further evidence that IL-21 is important in the...

New method to overcome multiple drug resistant diseases developed by Stanford researchers

...tuation by adding another molecule to the mix to inhibit the pump, keeping it busy so the medication can slip in while the pumps are occupied with the decoy molecule. But if any of the molecules make their way into healthy cells, they can gum up the proper functioning of the pumps in those cells, too, add...

Myostatin inhibitors may improve recovery of wartime limb injuries

...." A $1.2 million grant from the Office of Naval Research to Dr. Hamrick is enabling laboratory studies of two experimental myostatin inhibitors: a decoy receptor and a binding protein, both developed by MetaMorphix, Inc. of Beltsville, Md. Both inhibitors have been shown effective in muscle regeneratio...

Scientists discover new role for miRNA in leukemia

... microRNA called miR-328 binds with a protein that, in blast phase CML, prevents immature blood cells from maturing. We believe that miR-328 acts as a decoy molecule that normally ties up the protein, which enables the white blood cells to mature as they should, Perrotti says. During progression from chr...

Story ideas from molecular & cellular proteomics

...ase of the larvae, the scientists suggest that although the chemicals secreted prompt the human immune system to attack them, these chemicals act as a decoy so that the larvae themselves are not destroyed and can spread at will. The chemicals released by the eggs also attract molecules from the immune syst...

Quack of Gurgaon Confesses of Aborting 250 Female Fetuses

...linic. Acting on a complaint by the health department, the police raided the clinic after the doctor did conduct a sex determination test on a decoy female customer sent by the authorities. O.P. Mittal, the head of Haryana's health services, led the raiding team, which recovered the ultraso...

Doctor Caught Red-Handed For Conducting Sex-Determination Test

... unborn child//. Vijay Bhargawa was caught immediately after she conducted the test at Rewari town and disclosed the sex of the unborn child to a decoy customer sent to her by state health officials. A bribe of Rs.2,350 allegedly paid for the test was recovered from her. Sex determination ...

Punjab Government To Clamp Down On Sex Determination Tests

... The authorities in India’s Punjab state are using decoy customers to trap doctors who conduct sex determination tests for unborn ba...o is less than 800 females for every 1,000 males. Officials said the decoy customers would be paid up to Rs.5,000 to help nab diagnostic centers indul...
Decoy in Medical Technology

BioMarin Partner AnGes MG, Inc. Submits BLA to Japanese Ministry of Health

...rrent programs include the Hepatocyte Growth Factor (HGF) genetic medicine which improves blood circulation by regenerating blood vessels, and an NFkB decoy that controls various types of inflammation. Forward-Looking Statement This press release contains forward-looking statements about the business pro...

Vical Licensee AnGes MG Announces Positive Results of Phase 3 Angiogenesis Trial in Japan

... subsidiaries, is engaged in developing three new medicines: HGF genetic medicine which improves blood circulation by regenerating blood vessels, NFkB decoy which controls various inflammations, and HVJ envelope vector for non-viral drug delivery and discovery. Additional information on AnGes is available ...
Decoy in Biological News

Scientists determine drug target for the most potent botulinum neurotoxin

...k the toxins action, the researchers designed four decoy protein fragments that mimic the structure of the ...arily binds. The toxin then attaches itself to the decoy fragments instead of to the cells protein. This re...o the protein inhibitors. They found that all four decoy proteins are efficient at inhibiting the toxins bi...

Decoy makes sitting duck of superbugs

...n a couple of years and at a fraction of the normal cost. The technology can give fresh patent life to existing antibiotics - when combined with a decoy they can be patented as a new drug. This comes at a time when the number of new antibiotics receiving approval has dramatically declined. Faced wi...

Odd protein interaction guides development of olfactory system

...th derailed and Wnt5 are known to play key roles in the growth and development of the nervous system. In the antennal lobe, derailed is acting as a decoy receptor, said U. of I. cell and developmental biology professor Huey Hing, who led the study. It is nonproductively just sucking up the ligand. No...

Cancer-killing invention also harvests stem cells

...bind to TRAIL, but only two trigger cell death. The other three are called decoy receptors. Healthy cells contain a lot of decoy receptors, giving them a natural protection against TRAIL, whereas cancer c...

Decoy pill saves brain cells

... The researchers injected laboratory mice with a decoy peptide containing a snippet of a receptor that fa...ped the toxic enzyme calpain would latch on to the decoy instead of the actual receptor, averting brain dam...ed a calcium-calpain feedback loop, treatment with decoy peptides might save some cells, Baudry said. ...

Tool developed to silence genes in specific tissues using RNAi

...if they could produce a double-stranded RNA that mimics the RNA produced by a gene they wish to silence, RNAi would do the job for them. Producing the decoy "small RNAs" that trigger RNAi has become a fairly simple process, Wilkinson says, but the difficulty has been to use these matches only in specific t...

Grabbing addiction by the tail

...have sidestepped this problem by crafting a peptide that mimics a portion of the tail of the glutamate receptor and, once inside a neuron, serves as a decoy to prevent the loss of glutamate receptors. Yu Tian Wang, an HHMI international research scholar, and colleagues at the University of British Colum...

UCLA scientists reveal how Nipah virus infects cells

...neered a harmless virus with Nipah virus proteins embedded in its coat. The decoy virus successfully infected cells vulnerable to the Nipah virus, but could not infect Nipah-resistant cells. In the final step, the decoy virus entered nerve cells and cells lining blood vessels by latching onto E...

New binding target for oncogenic viral protein

...wever, unlike the other substrates recognized by Fbw7, T antigen is not destroyed by the cell. Drs. Clurman and Welcker suspect that by acting as a decoy and binding to Fbw7, T antigen protects cellular Fbw7 targets that facilitate viral replication and tumorigenesis. "I think this work underlines th...
Decoy in Biological Technology

Anesiva Announces Second Quarter 2008 Financial Results and Update

...hich gradually reversed several weeks following treatment. Additional Development -- Anesiva out-licensed worldwide rights to its NF-kappa B decoy program to Transcription Factor Therapeutics, Inc. Anesiva will receive an upfront licensing fee, and will be entitled to receive milestone ...

Anesiva and Transcription Factor Therapeutics, Inc. Announce Licensing Agreement for Development and Commercialization of NF-kappa B Clinical Program

...ut-licensed all worldwide rights to its NF-kappa B decoy (NF-kB Decoy) program, which includes the clinical...erapeutics, Inc. (TFT). NF-kB Transcription Factor decoy inhibits NF-kappa B, a protein implicated in the i...nd intellectual property associated with the NF-kB decoy program will be transferred to TFT. "Anesiva con...

Naglazyme Approved by Japanese Ministry of Health

...rrent programs include the Hepatocyte Growth Factor (HGF) genetic medicine which improves blood circulation by regenerating blood vessels, and an NFkB decoy that controls various types of inflammation. Forward-Looking Statement This press release contains forward-looking statements about the business p...

Bruker Announces Availability of New HUPO World Congress Proteomics Posters on Web Site

...oster T174 -- Managing Proteomics Data from Data Generation and Data Warehousing to Central Data Repository and Journal Reviewing Poster W294 -- decoy Strategy Applied to a Multi Workflow Proteomics Approach Poster W295 -- Software-supported Process Optimization for Magnetic Beads Purification ...

Is traditional voice quality an oxymoron with today's cellular, VoIP?

...fee phone? What about a phone you throw away with 30 minutes of talk time that's somehow wedged into a thermal cup? It could be great for drivers as a decoy for all their phone calls. While they don't ticket you for drinking coffee in a car, some municipalities are ticketing cell phone users. Some say cell...
Decoy in Biological Products

TypeOne Restriction Inhibitor from EPICENTRE Biotechnologies

Description:...ge protein called "ocr", TypeOne Inhibitor is readily electroporated into cells along with transforming DNA. In vivo the protein acts as a molecular decoy that blocks the DNA binding site of type I R-M enzymes and inhibits DNA cleavage....
Company:EPICENTRE Biotechnologies
Decoy in Biological Dictionary

Hepatocytes

... hepatocytes , ... Incubation of rat hepatocytes with Hcy (50–200 µ) caused a significant increase ... When hepatocytes were transfected with decoy AP-1 oligodeoxynucleotide to ... Human hepatocytes generated in this model retained functional properties of ... To identify human hepatocytes...

Cork

...ian Olympic-training Regatta, Kingston, a ... WE Cork offers the highest level of experience and quality in natural cork . ... expansion joints, decoy blocks, cork hand bags and wallets. ... Open source travel guide to Cork , featuring up-to-date information on ... Cork is the anglicised vers...
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