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DYNACTIN in Medical News

Discovery of Agile Molecular Motors Could Aid in Treating Motor Neuron Diseases

...e long distance transport. Earlier this year, as reported in The Journal of Cell Biology, researchers in Holzbaur’s lab found that a mutation in dynactin leads to degeneration of motor neurons, the hallmark of motor neuron disease. This mutation decreases the efficiency of the dynein-dynactin motor in “...
DYNACTIN in Biological News

Mayo Clinic: Brain disorder suggests common mechanism may underlie many neurodegenerative diseases

... Perry syndrome have mutations in a subunit of the dynactin complex (DCTN1; p150glued), which is essential to ...isease, the molecular motors (for example, dynein, dynactin and kinesin) that drive transport from distant ner...ene, whose protein produces a large subunit of the dynactin complex known as p150glued. This protein is essent...

Discovery of agile molecular motors could aid in treating motor neuron diseases

...ive long distance transport. Earlier this year, as reported in The Journal of Cell Biology, researchers in Holzbaur's lab found that a mutation in dynactin leads to degeneration of motor neurons, the hallmark of motor neuron disease. This mutation decreases the efficiency of the dynein-dynactin motor in "...
DYNACTIN in other areas

Dynactin - Wikipedia, the free encyclopedia

Dynactin or Dynein activator complex is a multi-subunit protein found in eukaryotic cells that aids in bidirectional intracellular organelle transport by binding to dynein and Kinesin II and linking them to the organelles to be transported.

DCTN1 - Wikipedia, the free encyclopedia

The p150Glued component of the dynactin complex binds to both microtubules and ... Cytoplasmic dynein binds dynactin through a direct interaction between the ...

Dynactin 4 (Dctn4)

Norway rat protein-coding gene Dctn4. Represented by 45 ESTs from 34 cDNA libraries. ... Rattus norvegicus dynactin 4, mRNA (cDNA clone MGC:114292 IMAGE: ...

Dynactin 5 (Dctn5)

Norway rat protein-coding gene Dctn5. Represented by 87 ESTs from 47 cDNA libraries. ... Rattus norvegicus dynactin 5, mRNA (cDNA clone MGC:112788 IMAGE: ...

Everest Biotech Ltd Goat Anti-Dynactin Antibody

Online Catalogue > 14-3-3 sigma to FZD9 > Goat Anti-Dynactin Antibody ... Principal Names: DCTN1; dynactin 1 (p150, glued homolog, Drosophila); P135; DP ...

DCTN1 - dynactin 1 (p150, glued homolog, Drosophila) - Genetics Home ...

Dynactin-1 interacts with several other proteins to form a complex (a group of ... The dynactin complex, dynein, and microtubules work together like a conveyer ...
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