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DPP in Medical News

Community-based diabetes prevention program shows promise

...monstrate that the YMCA is a promising vehicle for the dissemination of the dpp lifestyle intervention into the communityIn this pilot study, people at hig...icant reductions in total cholesterol. Given these results, delivery of the dpp via the YMCA warrants further study as a model for the wide-scale dissemina...

Stanford researchers synthesize compound to flush HIV out of hiding

...y're not optimized for human therapy." But with synthetic prostratin and dpp available, researchers can take the basic compounds and tinker with the str...ed." Wender's team developed their method of synthesizing prostratin and dpp by using a renewable resource, croton oil, made from the seeds of a small t...

The International Diabetes Federation Launches US$ 10 Million Grant to Improve Diabetes Care

...burgh, Pennsylvania, a translational research project is being facilitated where people in urban communities with high risk for diabetes are using the dpp lifestyle interventions and doing prevention programmes in their churches and wellness centres. Thus far, the programme has been highly effective and ...

Bladder Control following Weight loss in women with Prediabetes

...weight through calorie reduction and increased physical activity.” The dpp randomly assigned 3,234 overweight people with above normal blood glucose l... of the pelvic floor muscles that support the bladder. However, in the dpp participant loss of weight did not alleviate urge incontinence — leakage of...

Patients Miss Appointments...Regularly

...y problems were caused when the patients miss appointments. Meanwhile dpp also added that missing appointments is leading to the NHS losing lots of money. Dr Chaand Nagpaul, GP and dpp Spokesman, said, "People are still missing appointments even when they make...

More Britons Take To Alcohol Because Of Stress

...y Developing Patient Partnerships (DPP). The dpp conducted a poll of 1,000 people last year. One th...such situations, it reported. And, while the dpp said it was important to talk about stress to help...as depression, it is not an illness in itself. The dpp is issuing guidance to help people deal better wit...
DPP in Medical Technology

FDA Accepts Investigational New Drug Application for ARI-2243 and a First in Man Clinical Trial Set to Begin During the First Half of 2008

...ic conversion as it passes through the gut and into systemic circulation, which limits the exposure of the active species to unwanted targets, such as dpp 8 and 9. Such "soft drug" properties of ARI-2243 confer functional selectivity and are believed to contribute to a favorable therapeutic index in anim...

Isis Initiates Phase 1 Study of ISIS 325568 Targeting Glucagon Receptor to Treat Type 2 Diabetes

... dual mechanism of action in insulin-resistant animal models. Furthermore, the favorable effects on GLP-1 that we have seen exceed those observed with dpp IV inhibitors, and there was no evidence of hypoglycemia or GI side effects. These preclinical findings suggest that ISIS 325568 could offer disease m...

Arisaph Pharmaceuticals Announces Results of its Potent Smart DPP-4 Inhibitor, ARI-2243, at the ADA

...hich limits the exposure of the active species to unwanted targets, such as dpp 8 and 9. The conversion product, ARI 2498 is a millimolar inhibitor of the DPP family, in particular, dpp 8 and 9. Such soft drug inactivation confers functional selectivity and con...
DPP in Biological News

Making flies sick reveals new role for growth factors in immunity

...group, is the growth factor Decapentaplegic (Dpp). dpp acts as a hormonal signaling device, binding to ce...ifferent type of cell. Studies have shown that dpp in the fruit fly and its counterparts in other ani...ional in mammalian cells, and the human version of dpp BMP 2/4 also works just fine when injected into ...
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