DNA Molecules Used To Assemble Nanoparticles
University of Michigan researchers have developed a faster, more efficient way to produce a wide variety of nanoparticle drug delivery systems, using DNA molecules to bind the particles together. Nanometer-scaled dendrimers can be assembled in many configurations by using attached lengths of single-stranded DNA molecules, which naturally bind to other DNA strands in a highly specific fash...Viral DNA sequence a possible trigger for breast cancer
A small sequence of DNA in the envelope (Env) protein of a mouse breast tumor virus (called MMTV) can transform breast cells into cancer cells, according to a study by Katz et al. in the February 7 issue of The Journal of Experimental Medicine. The ability of this motif to transform cells single-handedly suggests that viral infection may be an important and previously unrecognized trigger for bre...Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer
Deficiencies in the ability of cells to repair damaged DNA are associated with an increased risk of breast cancer, according to a new study in the January 19 issue of the Journal of the National Cancer Institute. is the system of defenses designed to protect the integrity of the genome. Studies have suggested that deficiency...Novel technology detects human DNA mutations
Researchers at today reported unprecedented benefits in the company's technology for the medical analysis of human DNA. genotyping...Dinosaur DNA? New Patent Covers Degraded DNA recovery
The US Patent Office issued Patent # 6,872,552, "A Method of Reconstituting Nucleic Acid Molecules" today to Burt D. Ensley, Ph.D, Chairman of MatrixDesign, and CEO of DermaPlus, Inc. The patent covers methods for recovering and reconstituting genes from "degraded" DNA samples, and could allow scientists to reassemble everything from prehistoric, extinct animals to unsolved crime scenes. "...DNA/RNA Aptamer Microarray - Comprehensive Service from LC Sciences
Description:LC Sciences provides unique aptamer microarray services using a novel Paraflo technology, aptamer sequence databases, and sequence design software to suit your needs for basic research and screening of aptamers as drug candidates. This comprehensive service includes assistance with sequence design, synthesis of standard or custom DNA/RNA (2-OMe) microarrays, binding assays using proteins, nucleic...Rapid-Screen Arrayed cDNA Library Panels Master Plates -Human Placenta from OriGene Technologies
Description:The Rapid-Screen cDNA Library Panels were designed for full-length gene cloning and require just three sets of PCRs to identify the desired cDNA clone. The first PCR analysis is performed in a 96-well "Master Plate," where each well contains plasmid DNA from 5,000 clones. Having identified the positive well(s) by gel electrophoresis of the reaction products, the second PCR analysis is carried out...Rapid-Screen Arrayed cDNA Library Panels Master Plates -Human Heart from OriGene Technologies
Description:The Rapid-Screen cDNA Library Panels were designed for full-length gene cloning and require just three sets of PCRs to identify the desired cDNA clone. The first PCR analysis is performed in a 96-well "Master Plate," where each well contains plasmid DNA from 5,000 clones. Having identified the positive well(s) by gel electrophoresis of the reaction products, the second PCR analysis is carried out...Rapid-Screen Arrayed cDNA Library Panels Master Plates -Mouse Testis from OriGene Technologies
Description:The Rapid-Screen cDNA Library Panels were designed for full-length gene cloning and require just three sets of PCRs to identify the desired cDNA clone. The first PCR analysis is performed in a 96-well "Master Plate," where each well contains plasmid DNA from 5,000 clones. Having identified the positive well(s) by gel electrophoresis of the reaction products, the second PCR analysis is carried out...New Microarray Labeling Kit for Preparing cDNA Probes
A more reliable and reproducible way to create fluorescently orradioactively labeled cDNA David T. Wong Heidi Davis Darryl Garrison TerryPayette Matt Lundy Kim Kuplent Mary A. Buchanan Joseph A. Sorge Rebecca L. Mullinax Stratagene Phenogenex Nucleic acid micro...Purified Single-Stranded M13 DNA for Automated Sequencing
A streamlined and reliable method to obtain high-quality single-strandedDNA Stratagene M13 DNA purification kit allowseasy, quick, and reliable purification of bacteriophage single-stranded DNA. Theyield of single-stranded DNA recovered from phage lysa...Low Abundance cDNA Cloned Using Stratagenes Human Universal cDNA Library
Department of Cell Biology, Clevela...Fast and Easy Isolation of PCR-Ready Genomic DNA from Whole Blood
...Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase
pfuturbo DNA polymerase for robust, high-fidelity PCRamplification Holly Hogrefe Brad Scott Kirk Nielson ValerieHedden Connie Hansen Janice Cline Frances Bai Jeff Amberg RondaAllen Mark Madden Stratagene an improved version of Pf...Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis
A novel modification of a new technology born of genetic engineering, and known as naked DNA vaccination, holds the potential of overcoming autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. The vaccine is currently being successfully tested in animals. In multiple sclerosis (MS) and rheumatoid arthritis (RA), the body essentially attacks itself, caus...Chromosome Ends Trigger DNA Damage Response For Telomere Protection
Researchers from the Salk Institute for Biological Studies have suggested that a localized DNA damage response at telomeres after replication is essential for recruiting the //processing machinery that promotes formation of a chromosome end protection complex. Telomeres, the ends of linear chromosomes, represent a problem for the control of genome stability and the DNA damage machinery...Methyl-DNA binding Proteins To Fight Cancer
Russians researchers are exploring the possibility for using Kaiso protein for early detection of cancer. They are developing this new approach to treat intestinal cancer at the Bioengineering Centre, Russian Academy of Sciences, //under Anna Prokhorchuk's guidance jointly with American colleagues sponsored by the international CRDF foundation and the Federal Agency for Science and Inno...DNA biochip for genetic screening
A scientist from the University of Houston has developed a chemical process for building a device that could help doctors predict a patient’s response to drugs or screen patients for thousands of genetic mutations and diseases, all with one simple lab test. The DNA chip is similar to a computer chip but imbedded with DNA molecules instead of electronic circuitry. It is designed to pro...VERSANT HIV RNA 3.0 Assay (bDNA)
Description:The VERSANT HIV-1 RNA Assay (bDNA) delivers unmatched precision and reproducibility, so you can be confident that you're providing physicians with viral load values they can trust.you detect significant changes at the low end and at other critical decision points - without the variability seen with other assays. If you need more reasons to choose VERSANT HIV bDNA, consider this: it's the only...Trans-Blot SD DNA/RNA Blotting Kit
Description:The Trans-Blot SD semi-dry transfer cell allows fast, efficient and economical blotting. Using a platinum-coated titanium plate as the anode and a stainless steel plate as the cathode, the Trans-Blot SD cell transfers in a horizontal configuration without a buffer tank or gel cassettes....NUNC Polyolefin Sealing Tape, Clear, Non-Sterile, Certified DNAse/RNAse-free
Description:Amplification Tape 96 featuring 3M adhesive technology. Good optical quality. Minimal autofluorescence. Certified RNase and DNase free....NIEHS Researchers Identify Enzyme Critical in DNA Replication
BETHESDA, Md., July 5, 2007--In this weeks issue of Science,researchers from the National Institute of Environmental HealthSciences (NIEHS) and Umeö University in Sweden report animportant discovery about a critical new role that an enzyme calledDNA polymerase epsilon plays in replicating DNA in higher organismssuch as yeast and perhaps even humans. The study places us one ste...Vision Deficit in Retinitis Pigmentosa Mice Corrected with DNA Nanoparticles
CLEVELAND--(BUSINESS WIRE)--Jun 4, 2007 - Copernicus Therapeutics,Inc. announced today that a research team at University of OklahomaHealth Sciences Center, led by Dr. Muna Naash, Professor of CellBiology, demonstrated that Copernicus' DNA nanoparticles correctedvision defects in a mouse model of retinitis pigmentosa (RP). Thesefindings were presented at the American Society of Gene Therapy...