DMSO

Pennsaid(R) Phase 3 study results to be published in leading international PAIN journal

...ide (DMSO) compared with those of topical placebo, dmso vehicle and oral diclofenac for knee osteoarthriti...o, 2) topical placebo containing a small amount of dmso for blinding purposes (DMSO facilitates delivery o...icle-control (containing the same concentration of dmso as in Pennsaid) plus oral placebo, 4) topical plac...

Frost & Sullivan Recognizes Lifeblood Medical for Its Innovation in Organ Preservation and Development of the Lifor(R) Solution

...ring and preservation. Further, Lifeblood Medical does not use dimethyl sulfoxide (DMSO) in its product. A commonly used chemical in cryopreservation, dmso is considered to be toxic to cells. Lifeblood has been able to achieve better results through this solution. "Its innovative technology provides Lif...

DMSO in Medical Products

Echo 550 Compound Reformatter

Description:... based on focused acoustic energy. Monitoring of acoustic energy reflected from well plate fluids enables the Echo 550 to measure the water content in dmso and determine well volume....
Company:Labcyte Inc.

AliQuot

Description:...Dead Volume: 3 ml (recoverable) Chemical compatibility: Aqueous solutions, dmso Voltage: 100-120 V AC 45-66 Hz, 210-240 V AC 45-66 Hz Machine dimensions: ...eplacement polyurethane tubing kit (assembled including valve); Replacement dmso resistant tubing Ordering Information X3400 / X3401 - aliquot 240 V / 110 ...
Company:Genetix

DMSO in Biological News

Cholesterol-lowering drugs and the effect on muscle repair and regeneration

...ll lines isolated from quadriceps muscle biopsies. SC were mixed and grown for 48 hours with several concentrations of statin: 0.0, 0 plus the solvent dmso (control), 0.05, 0.1, 1.0, 10, or 100M. The MTS assay was utilized to measure cell viability/reproducibility. Additionally the investigators deter...

DMSO in Biological Technology

Dispensing 0.5μL to "Dry" 384 Plates with the Sciclone ALH

...entrations and compositions, solute (compound) characteristics and solute concentration. The current study represents 2.8g/L tartrazine dissolved with dmso and dispensed into untreated, flat-bottomed, polystyrene plates only. Under these conditions we demonstrated that it is feasible to dispense sub micro...

Monitoring Receptor-Mediated Changes in [Ca2+]i Using Single-Wavelength and Dual-Wavelength Indicators on the FlexStation Workstation

... probenecid in 5 mL of 1 M NaOH then add 5 mL of wash buffer and agitate vigorously. Step 3 Fluo-3 and Fura-2 stock solutions. Add 25 L dmso to 50 mg Fluo-3 AM or Fura-2 AM (final concentration ~2 mM). Step 4 Dye loading buffer. Mix 25 L Fluo-3 or Fura-2 stock solution...

A Microtiter-based Assay for the Determination of ID50s of b-lactamase Inhibitors Employing Reporter Substrates Detected at UV or Visible Wavelengths (MaxLine Application Note #20)

... Deep well microplate 5. Multichannel pipette 6. dmso 7. Imipenem and nitrocefin 8. β -lactama... (PIPES) buffer, pH 7.0 with no added Zn 2+ to produce a 3 mM solution. 5% dmso can be used if needed to aid in dissolving the inhibitors. Step 4 In...

Fluorometric Protease Assays in the SpectraMax Gemini Microplate Spectrofluorometer: Example Using Caspase3 (MaxLine Application Note #35)

...he 5X Reaction Buffer and 5 L of DTT, both included in the kit, with 795 L of deionized water.) Stock ZDEVDAMC (10 mM) was prepared by adding 520 L of dmso into the vial of ZDEVD AMC. Working solutions of ZDEVDAMC stock were typically 1:100 dilutions of the stock, i.e. 5 L of the stock solution into 495 L...

Measurement of proteasome inhibition in live cells in Molecular Devices microplate fluorometers

...Devices) METHODS The stock solution of ALLN (a well-characterized proteasome inhibitor) was prepared by dissolving in dmso to a concentration of 10 mM. The HEK 293 ZsGreen Proteasome Sensor Cells were cultured in DME + 10% FBS + 1% Pen/ Strep/L-glutamine + 200 g/mL of G418...

Development of Radioligand Binding Assays for the Motilin Receptor Using ScreenReady Targets.

...to-use for radioligand binding assays Stable for three months at 4C Microformatted assays (25 μl or higher) Resistant towards dmso (1% - 5%) Integration into automated systems such as PerkinElmers PlateTrak, MiniTrak and MultiPROBE II Supplied with the appropriate P...

Receptor Binding Assays using Fluorescence Polarization Detection: the [FP]2TM Characterized Tracers

...n for peptidic ligand binding to GPCR targets. In addition to the eight ligands described here, fully optimized kits (pharmacology, assay performance, dmso tolerance, kinetics and stability) are available. See [FP] 2 brochure, reference number H78392, for more detailed lists. Principles of Flu...

Development of an adrenergic α2a receptor binding assay using the LEADseeker Multimodality Imaging System

...

dmso tolerance Dilutions of dmso were prepared in assay buffer to give a range of c...own in Figure 2 indicate the assay was tolerant to dmso up to a final concentration of 1% (v/v). <...

The development of a serotonin 5-HT2C receptor-binding assay using the LEADseeker Multimodality Imaging System

...gents were added in the following order: buffer or dmso solution, unlabeled ligand (NSB wells), labeled li... µM) in addition to the above. 5. For dmso tolerance studies, dmso was diluted in binding buffer to give final concen...

The development of a somatostatin sst4 receptor-binding assay using the LEADseeker Multimodality Imaging System

... order: assay buffer or buffer containing 2% (v/v) dmso solution, unlabeled ligand (NSB wells), labeled li...igand prepared in assay buffer containing 2% (v/v) dmso was added with (3-[ 125 I] iodotyrosyl 11 ) Soma...ncentration 2 µM).

5. For dmso tolerance studies,...

DMSO in Biological Products

EGTA; AM; 10mM DMSO solution from AnaSpec

Description: ...
Company:AnaSpec

A23187, Mixed Calcium-Magnesium Salt from Calbiochem

Description:...m dose-response data are not required. Purity: ≥98% by TLC. Soluble in dmso or EtOH. For use in aqueous systems, preparation of a 10 mM stock in dmso is recommended. Microliter amounts of this solution can be added to H 2 O w...
Company:Calbiochem

Tunicamycin, Streptomyces lysosuperficus from Calbiochem

Description:...ilization in cells. Purity: ≥95% by HPLC (A+B+C+D). Soluble in DMF, DMSO, or Pyridine. Aqueous solutions can be prepared from stock solutions in dmso by diluting with H 2 O at pH 8.0 to 10.0 or with appropriate buffers at pH >7.0 (preferably >8.0). RTECS YO7980200, CAS 11089-65-9, M.W. 840.9. M.W. ...
Company:Calbiochem

PTP1B Inhibitor from Calbiochem

Description:...o a novel site away from the catalytic pocket and inhibits PTP1B activity by preventing closure of the WPD loop. Purity: ≥95% by HPLC. Soluble in dmso or EtOH. M.W. 741.5. References: Wiesmann, C., et al. 2004. Nat. Struct. Mol. Biol. 11, 730....
Company:Calbiochem

MMP-2/MMP-9 Inhibitor IV [SB-3CT] from CHEMICON

Description:...ased inhibitor of human gelatinases. • Molecular weight: 306.4 • Molecular Formula: C(15)H(14)O(3)S(2). • The inhibitor is soluble in dmso (100mg/mL)....
Company:CHEMICON

RVT405DDA Refrigerated Vapor Trap from Thermo Scientific

Description:... The RVT405DDA Refrigerated Vapor Trap is specifically designed for efficient trapping of high boiling solvents such as dmso and DMF in the SpeedVac™ DDA™ systems. Its constant temperature refrigeration system set at -5 o C creates optimum cryopumping conditions ...
Company:Thermo Scientific

Dermal Fibroblasts, Rabbit from CHEMICON

Description:... Description: Kit containing Dermal Fibroblasts (rabbit) and media. Cryo-preserved cells in medium containing 20% FBS and 10% dmso at passage 25 (approx), supplied with kit (500 mL) of optimized medium.This cell culture is supplied as a long-term culture, and is guaranteed to prov...
Company:CHEMICON

Vaginal Keratinocyte Progenitors, Rabbit from CHEMICON

Description:... Kit containing Vaginal Keratinocyte Progenitors, Rabbit, and media. Cryo-preserved cells in medium containing 20% FBS and 10% dmso at passage 25 (approx), supplied with kit (500 mL) of optimized medium.This cell culture is supplied as a long-term culture, and is guaranteed to prov...
Company:CHEMICON

Fragment Library I: Large Volume with mixtures from ActiveSight

Description:... 96 shape-diverse mixtures of 4 (5 uL each) PDB and dictionary files for structure refinement Individual compounds are dissolved in dmso at ca. 200 mM, mixtures of 4 are at ca. 50 mM. Supplied in 5 96-well trays. Dilute library with protein crystallization solution to make soak solut...
Company:ActiveSight

Cleland’s REDUCTACRYL™ Reagent from Calbiochem

Description:...e can be reduced completely to glutathione in 15 minutes at room temperature, pH 7.5. Can be used in either aqueous or organic solvent systems such as dmso or EtOH. Reduction capacity: >0.06 meq/g of resin. RTECS EK1610000, CAS 3483-12-3. ...
Company:Calbiochem

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