Navigation Links
DHFR in Medical News

Cancer Scientists' Gene Research Offers New Treatment Hope

...or DHFR. When it is switched off, the rapidly dividing cancer cells are starved of a vital building block - a chemical called thymine. "Inhibiting the dhfr gene could help to prevent the growth of neoplastic cancer cells - ordinary cells which develop into tumour cells - such as in prostate cancer cells,"...

Role of RNA in Checking the Development of Tumors

...determining whether the gene is "on" or "off". The dhfr gene produces an enzyme that controls thymine prod... in rapidly dividing cells. "Inhibiting the dhfr gene could help prevent the growth of neoplastic c...ng how we can use the RNA to switch off or inhibit dhfr and other genes may have important therapeutic imp...
DHFR in Medical Technology

Arpida Comments on FDA's Anti-infective Drugs Advisory Committee Outcome

...and is the first antibiotic in the dihydrofolate reductase (DHFR) selective inhibitor class to demonstrate efficacy against cSSSIs caused by MRSA. The dhfr class has been proven safe and effective in more than four decades of clinical use. About Arpida Arpida (SWX: ARPN) is a biopharmaceut...

Pivotal Phase III Data Confirm the Efficacy and Safety of Arpida's Intravenous Iclaprim in Treating Patients With Complicated Skin and Skin Structure Infections

...and is the first antibiotic in the dihydrofolate reductase (DHFR) selective inhibitor class to demonstrate efficacy against cSSSIs caused by MRSA. The dhfr class has been proven safe and effective in more than four decades of clinical use. In March 2008, Arpida completed the U.S. filing of the New Drug ...

Interim Safety Analysis Supports Continuation of Allos Therapeutics' Pivotal Phase 2 PROPEL Trial of PDX in Patients with Peripheral T-cell Lymphoma

...able safety and efficacy profile relative to methotrexate and certain other dhfr inhibitors. About Allos Therapeutics, Inc. Allos Therapeutics is a biop...fety and efficacy profile of PDX relative to methotrexate and certain other dhfr inhibitors, the potential safety and efficacy of PDX for the treatment of P...

Interim Response and Safety Analyses Support Continuation of Allos Therapeutics' Pivotal Phase 2 PROPEL Trial of PDX in Patients with Peripheral T-Cell Lymphoma

...able safety and efficacy profile relative to methotrexate and certain other dhfr inhibitors. About Allos Therapeutics, Inc. Allos Therapeutics is a biopha...fety and efficacy profile of PDX relative to methotrexate and certain other dhfr inhibitors, the potential safety and efficacy of PDX for the treatment of P...

Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma

...and clinical data in a variety of tumors, suggest that PDX may have a favorable safety and efficacy profile relative to methotrexate and certain other dhfr inhibitors. About Allos Therapeutics, Inc. Allos Therapeutics is a biopharmaceutical company focused on the development and commercialization of sma...

Arpida Announces Promising Results of "First-In-Man" Studies With AR-709

...ould be developed with appropriate players in this field, could have the added benefit of avoiding unnecessary systemic exposure." AR-709 is a novel dhfr inhibitor with an outstanding microbiological activity against streptococci in general and, importantly, against multi-drug resistant Streptococcus pn...

Hana Biosciences Announces Data to be Presented On Talvesta (Talotrexin) for Injection at The American Association for Cancer Research Annual Meeting

... of various types of cancers. Talvesta has demonstrated enhanced antitumor activity in a broad spectrum of preclinical studies by targeting the enzyme dhfr to prevent DNA synthesis in tumor cells and inhibit tumor growth. These studies suggest that Talvesta, as compared to methotrexate, enters into cells ...

Allos Therapeutics' PDX Granted Orphan Medicinal Product Designation by the European Commission

...nd clinical data in a variety of tumors, suggest that PDX may have a favorable potency and toxicity profile relative to methotrexate and certain other dhfr inhibitors. About Peripheral T-cell Lymphoma Peripheral T-cell lymphomas, or PTCLs, are a biologically diverse group of blood cancers that account...

Allos Therapeutics Reports Results for Phase 3 Enrich Study of Efaproxyn in Women With Brain Metastases Originating From Breast Cancer

...ble potency and toxicity profile relative to methotrexate and certain other dhfr inhibitors. The Company believes PDX has the potential to be delivered as a...tial potency and toxicity profile of PDX relative to methotrexate and other dhfr inhibitors; the Company's projected timelines for conducting interim analys...
DHFR in Biological Technology

Arpida Announces Full Year 2007 Financial Results

...that is being developed for the treatment of upper and lower respiratory tract infections contracted in the community setting. The compound is a novel dhfr inhibitor with an outstanding microbiological activity against streptococci in general and, importantly, against multi-drug resistant Streptococcus pn...

Electroporation of Primary Bone Marrow Cells

...orometer. The stable integration of the dhfr gene was demonstrated by the acquired ability ... 10 days in culture. Cells receiving the dhfr plasmid were cultured with increasing a... was done to verify the presence of the dhfr gene within the cultured cells. High molecular wei...

Preparative SDS-PAGE Electrophoresis of a Recombinant Epstein-Barr Virus Encoded Protein and Its Application in Serodiagnostic Test Systems, Rev C

...proved by the use of purified recombinant EBV antigens. After cloning and high-level expression of a particular viral protein as dhfr fusion protein in Escherichia coli, we purified the recombinant antigen to near homogeneity with the help of continuous elution electrophor...

Translate High Yields of Biologically Active Proteins

... available kits were compared to that from the ActivePro Kit. Dihydrofolate reductase (DHFR): Activity was measured with a standard dhfr assay, which follows the rate of conversion of dihydrofolate and NADPH to tetrahydrofolate and NADP + through the successive de...
DHFR in Biological Dictionary

Gene amplification

...plification (in vivo) RNA amplification (in vivo) amplification , gene ... MTX-resistance in a tumor can occur by gene amplification of dhfr (but not often documented) ... Gene amplification ® overproduction of mdr1 ® drug resistance: ... ...
Other Tags
(Date:12/25/2014)... “ SmileStix ” was featured on NewsWatch as ... coolest mobile applications on the iOS, Android, and Windows markets. ... conducted the app review and shared with viewers how this ... The old saying goes, “A picture says a thousand words.” ... describe a single image, because each picture holds a unique ...
(Date:12/25/2014)... 25, 2014 Parker & Sons, Inc. ... service and affordable quality regarding heating, cooling and plumbing ... in 2014 by the “Queen of Clean” for impressive ... an impressive reputation over the years for providing outstanding ... range of contractor services for both homeowners and businesses. ...
(Date:12/24/2014)... TX (PRWEB) December 24, 2014 Connie ... specialist and functional medicine advocate with 30 years of ... trial to evaluate the health benefits of dietary detoxification. ... with new participants following excellent results from test patients ... When asked to explain her interest in conducting the ...
(Date:12/24/2014)... 24, 2014 Dr. Vu Ho, a ... of his practice and med-spa with the addition of ... list of cosmetic treatments and services. , “Silk Peel ... skin,” says Dr. Ho. “As a result it can ... wrinkles, sun spots, discolorations or blemishes.” , Similar to ...
(Date:12/24/2014)... The report “Stivarga (Colorectal Cancer) – ... current treatment landscape, unmet needs, current pipeline and commercial ... drug which is used in the treatment of colon ... is also prescribed to patients who suffer from advanced ... is a multi-kinase inhibitor and it blocks many enzymes ...
Breaking Medicine News(10 mins):Health News:An Application to Create Custom Stickers was Featured on NewsWatch Television on December 19, 2014 2Health News:Parker & Sons Announces Recognition In 2014 By The “Queen Of Clean” For Impressive Contractor Services In Arizona 2Health News:Parker & Sons Announces Recognition In 2014 By The “Queen Of Clean” For Impressive Contractor Services In Arizona 3Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 2Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 3Health News:Dr. Vu Ho Expands Facial Plastic Surgery Practice to Include New Skin Care Treatment 2Health News:Stivarga Colorectal Cancer Treatment Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Stivarga Colorectal Cancer Treatment Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3
(Date:12/11/2014)... 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has announced the addition of ... report to their offering. One ... adoption of multimodal biometric systems. Multimodal biometric systems ... for verification and identification purposes. This helps to ...
(Date:12/10/2014)... -- Valencell, a leader in performance biometric data sensor technology, ... its licensees for highly accurate, clinically validated biometric technology. ... from fitness and health sectors, but first responders/military and ... only as useful as the biometric data it delivers. ... long-term mass consumer adoption of wearable products," said Dr. ...
(Date:12/10/2014)... 9, 2014     ...   Jifflenow, a ... solutions for business-to-business (B2B) events, today announced a ... mobile near-field communication (NFC), Bluetooth low energy (BLE), ... http://photos.prnewswire.com/prnh/20140612/691055) , Jifflenow will integrate its ...
Breaking Biology News(10 mins):Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2Wearable Technology Products Demand Highly Accurate Biometric Technology 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3
Other Contents