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DESORPTION in Medical News

Bio-imaging mass spectrometry techniques reveal molecular details about complex systems

...nd Biochemistry, has been using a technique called desorption electrospray ionization (DESI). With DESI, a hi... Chemistry and Biochemistry, to use DESI and laser desorption single photon ionization mass spectrometry (LD/SPI...mmercial mass spectrometers that rely on the laser desorption of ions, according to Orlando. "We hope LD/SPI-...

Potential blood test for chronic sinusitis identified

...ad & Neck Surgery put the incidence at 2 percent. For this study, researchers analyzed protein expression in the blood using surface enhanced laser desorption ionization time-of-flight mass spectroscopy or SELDI-TOF-MS. The test is about 88 percent accurate. ...

Faster Test Detects Fake Tamiflu Drugs

...counterfeiters trying to make money off the demand for antivirals that fight the deadly disease. Chemists in Georgia are scheduled to describe how desorption Electrospray Ionization Mass Spectrometry (DESI-MS) can determine the authenticity of large batches of Tamiflu up to 20 times faster than conventional...

Researchers sharpen search for new marine medicines with novel techniques

...e of the journal Molecular Biosystems, the scientists describe success in using new technology called natural product MALDI-TOF (Matrix Assisted Laser desorption Ionization-Time of Flight) imaging mass spectrometry, an imaging technique that can uniquely probe the inner workings of marine organisms. In the c...

3 newly discovered ERK pathway proteins related to CagA induced disease

... The research team led by Prof. Zheng from Cancer Institute of Zhejiang University used ProteinChip platform, which is based on surface enhanced laser desorption / ionization time-of-flight mass spectrometry (SELDI-TOF-MS) technology, to study the global protein expression changes in AGS cells transfected with ...

Scientists Saying Against Trees Sparks Debate

...il, could diffuse out and be counted as "emitted" by the plant in their experiment. But Keppler rejects this, saying that this sort of methane desorption could only be partially responsible for the amounts of gas he found. Indeed, he suggests that Dueck's use of heavy isotopes may have actually ...

New Technique to Identify Bacteria for Food Safety

... detect and precisely identify bacteria, including dangerous E. coli, without time-consuming// treatments usually required. The technique, called desorption electrospray ionization, or DESI, could be used to create a new class of fast, accurate detectors for applications ranging from food safety to homelan...
DESORPTION in Medical Technology

Vermillion's Biomarkers Prove Beneficial in Identifying Women With Ovarian Cancer and Detecting Early-Stage Disease

...nd predict prognosis of ovarian cancer. Researchers at Vermillion and the University of Kentucky Chandler Medical Center used surface enhanced laser desorption ionization time-of-flight mass spectrometry (SELDI-TOF) to analyze ovarian cyst fluids and identify the underlying proteins that could serve as potent...
DESORPTION in Biological News

An easy way to find a needle in a haystack by removing the haystack

...mass spectra of particular kinds of metabolites in real samples. With the new experimental protocols they called "Matrix-Assisted Ionization/Laser desorption MAILD", the scientists were able to quickly and reliably determine more than 100 different analytes from single and small-sized samples. "The analysi...

Sensitive laser instrument could aid search for life on Mars

...s type of preparation can use up large amounts of sample and potentially introduce contamination. INL's method is based on a technique called laser desorption mass spectroscopy. By focusing a laser beam on a spot less than one-hundredth the width of a pencil point, the researchers can knock microscopic fragm...

American Chemical Society's Weekly PressPac - Oct. 10, 2007

...testing method that combines two state-of-the-art testing techniques called desorption electrospray ionization (DESI) and tandem mass spectrometry. In laboratory ...IMMEDIATE RELEASE Rapid Screening of Anabolic Steroids in Urine by Reactive desorption Electrospray Ionization DOWNLOAD PDF http://pubs.acs.org/cgi-bin/sample...

Researchers develop new method for facile identification of proteins in bacterial cells

... called peptides. The samples are then analyzed using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), which identifie...ichii Strain RW1 by Peptide Mass Fingerprinting Using Matrix-Assisted Laser desorption Ionization-Time of Flight Mass Spectrometry" was written by Rolf U. Halden,...
DESORPTION in Biological Technology

Using THERMAL DESORPTION GAS CHROMATOGRAPHY for the identification of fragrance and other components in cosmetic products

Introduction Cosmetic products such as soap, shampoo, lotions and creams are often scented with suitable compounds to improve their appeal. This application note describes an analytical method to identify the fragrance and other compounds contained within these cosmetic formu...

Prosolia to Introduce Omni Spray(R) Ion Source in 2-D Format

... INDIANAPOLIS, Dec. 8 /PRNewswire/ -- Prosolia, Inc. introduces a new advanced Omni Spray Ion Source model based on the desorption Electrospray Ionization (DESI) technology. The Omni Spray 2-D Ion Source has an automated surface platform which enables rapid sampling and surface im...

Analysis of Fuel Oxygenates by U.S. EPA Method 8260B Using Headspace Trap with GC/MS

...uilibrium headspace, instead of purging. This transports a significant and highly reproducible fraction of the analytes from the sample onto a thermal desorption trap, where they are retained and focused on a multi-bed adsorbent packing before injection onto the GC column. The headspace trap offers operators lo...

Direct Monitoring of Solid-Phase Peptide Synthesis by MALDI-TOF MS

... Overview Mass spectrometry has proven to be a valuable tool in verifying and improving peptide synthesis. Matrix Assisted Laser desorption Ionization (MALDI) Time-of-Flight (TOF) MS is particularly useful in that it is rapid, easy to use and requires relatively little maintenance. This wo...

IMPROVE SILENCING SUCCESS: siRNAs THAT WORK BETTER!

...her purity is required. As part of our rigorous quality control procedures, MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) mass spectrometry is used to analyze the molecular weight of each RNA oligonucle...

Cenix-Designed siRNAs for 95% of Human and Mouse Genomes

...ligonucleotides are analyzed for purity by capillary electrophoresis (CE) or HPLC. Furthermore, MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) mass spectrometry is used to analyze the molecular weight of each oligonucleotide (Figure 1). Finall...

Structural Analysis of Glycosylated Peptides in Complex Mixtures with Ion Trap MSn

...spray ionization. Alternatively, fractions may be collected after the HPLC separation and analyzed off-line by matrix-assisted laser desorption ionization (MALDI) or nanospray ionization. Peptides that do not correspond to predicted masses may be present in a ...
DESORPTION in Biological Products

Silencer Pre-designed siRNA, HPLC purified, annealed from Ambion

Description:...are guaranteed >97% pure. To ensure that the siRNAs are of highest quality, all RNA oligonucleotides are assessed by MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) mass spectrometry and the purity of all HPLC and PAGE purified oligonucleotides by analytical HPLC. Ambion also analyzes e...
Company:Ambion

Silencer Pre-designed siRNA, standard purity from Ambion

Description:...are guaranteed >97% pure. To ensure that the siRNAs are of highest quality, all RNA oligonucleotides are assessed by MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) mass spectrometry and the purity of all HPLC and PAGE purified oligonucleotides by analytical HPLC. Ambion also analyzes e...
Company:Ambion

Custom siRNA, PAGE purified from Ambion

Description:...are guaranteed >97% pure. To ensure that the siRNAs are of highest quality, all RNA oligonucleotides are assessed by MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) mass spectrometry and the purity of all HPLC and PAGE purified oligonucleotides by analytical HPLC. Ambion also analyzes e...
Company:Ambion

Silencer Pre-designed siRNA, HPLC purified from Ambion

Description:...are guaranteed >97% pure. To ensure that the siRNAs are of highest quality, all RNA oligonucleotides are assessed by MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) mass spectrometry and the purity of all HPLC and PAGE purified oligonucleotides by analytical HPLC. Ambion also analyzes e...
Company:Ambion

Custom siRNA, PAGE purified, annealed from Ambion

Description:...are guaranteed >97% pure. To ensure that the siRNAs are of highest quality, all RNA oligonucleotides are assessed by MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) mass spectrometry and the purity of all HPLC and PAGE purified oligonucleotides by analytical HPLC. Ambion also analyzes e...
Company:Ambion
DESORPTION in Biological Dictionary

Mass spectrometry

...rican Association for Mass Spectrometry (SAAMS) ... Samples can be submitted at any of the three mass spectrometry laboratories. ... Plasma desorption Mass Spectrometry (PDMS) utilizes fission fragments from ... Mass spectrometry is an analytical technique that identifies the chemical ... ...
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