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DAP12 in other areas

DAP12.

DAP12 is a transmembrane adaptor protein that is non-covalently ... DAP12 contains an. ITAM domain that preferentially recruits the protein tyrosine kinase ...

Innate Immune Responses to TREM-1 Activation: Overlap, Divergence, and ...

TREM-1 associates with and signals via the adapter protein DAP12/TYROBP, which contains an ITAM. ... DAP12 (KARAP) amplifies inflammation and increases ...

Intrapulmonary, Adenovirus-Mediated Overexpression of KARAP/DAP12 ...

KARAP/DAP12 also known as TYRO-BP (31) is an immunoreceptor tyrosine-based ... Paradoxically, KARAP/DAP12–/– mice also show deficits in osteoclast and ...

Chimeric NK-receptor–bearing T cells mediate antitumor immunotherapy

Murine CD3? chain, Dap10, and Dap12 cDNAs were cloned by reverse transcriptase ... Inefficient pairing of NKG2D with Dap12 compared with Dap10 may be responsible ...

Structural characteristics of zebrafish orthologs of adaptor molecules ...

The DAP12, FcR? and CD3? adaptors utilize cytoplasmic immunoreceptor tyrosine ... As DAP10 and DAP12 are adjacent genes in mammals and pufferfish (Guselnikov et ...

T Cells Gene-engineered with DAP12 Mediate Effector Function in an ...

T Cells Gene-engineered with DAP12 Mediate Effector Function in an NKG2D ... cells, T cells fail to express the activation-signaling molecule DAP12 even when ...
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