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Cytosolic in Medical Technology

Clinical Update - Debio 0614 (Istaroxime) in Acute Heart Failure

...potassium pump and restores the SERCA2 ATPase activity (Sarcoplasmic Reticulum Calcium ATPase 2 activity). The combined mechanism of action allows for cytosolic calcium accumulation during systole (inotropic response), as well as rapid sequestration of calcium during diastole and myocardial relaxation (lusitro...

CuraGen Announces New Preclinical Results with Belinostat and Velafermin to be Presented at AACR Annual Meeting

..."Velafermin (rhFGF-20) reduces fractionated radiation- induced oral mucositis in hamsters," (Abstract #3758) during the conference's cytosolic Signaling 2 poster session on Tuesday, April 17th in the Exhibit Hall, Poster Section 16 on Poster Board #15. About CuraGen CuraG...
Cytosolic in Medical Dictionary

Neutrophil

...phonuclear cell family... A neutrophil is a granulocyte (a type of white blood cell) that is designed to ... About 45% of the neutrophil cytosolic protein is made of migration inhibitory ... Neutrophil adhesion to either resting or activated endothelial cells was not ... The temperatur...

Lymphocyte

...cyte populations that are not eliminated ... Mouse protein-coding gene Lcp1. Represented by 1007 ESTs from 162 cDNA libraries. ... Lymphocyte cytosolic protein 1 (Lcp1) SELECTED PROTEIN SIMILARITIES ... Information about lymphocyte in the free online English dictionary and ... lymphoblast - an...
Cytosolic in Biological News

HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection

...ious effects on insulin secretion mediated through the oxidative stress pathway. They report a significant decrease in the levels of the antioxidants, cytosolic superoxide dismutase (Cu/Zn SOD) and glutathione, whereas mitochondrial SOD levels remained unaffected in pancreatic beta-cells (INS-1 cells) exposed ...

Biophysical Society announces winners of 2008 Student Travel Awards

...of Interfacial Water in Biological Systems. Sepehr Dadsetan, University of California, Davis, Store-Operated Ca2+-Induced Ca2+ Release Amplifies cytosolic Ca2+ Signaling and Prevents Store Refilling in Jurkat T Cells. Angel M. Davey, The Pennsylvania State University, Dynamics Imaging of Membrane ...

Researchers uncover protection mechanism of radiation-resistant bacterium

...han the most sensitive species. In the new study, which examined the functional consequences of this disparity, the researchers demonstrated that high cytosolic manganese and low iron concentrations enable resistance by protecting proteins, but not DNA, from IR-induced oxidative damage. ...
Cytosolic in Biological Technology

Monitoring fluorescence resonance energy transfer (FRET) between GFP fusions in lysates of the yeast Saccharomyces cerevisiae using the Varian Cary Eclipse

... changes in FRET between BFP and GFP in cytosolic lysates of yeast cells using the Varian Cary Eclip... the yeast expression plasmid pAS1N for cytosolic expression and transformed into the yeast strain ...gure 3) that FRET could be accurately monitored in cytosolic lysates from yeast cells. Cleavage of t...

Purification of Phosphoinositide 3-Kinase With UNO Columns

... and ion-exchange chromatography. The chromatograms (Figures 1 and 2) illustrate the use of an UNO Q1 column to partially purify a cytosolic phosphoinositide 3-kinase from a rat liver homogenate at a flow rate 5-fold higher than previously used with a conventional mono...

Your Data: Use of pSilencer 1.0-U6 siRNA Expression Vector in the Analysis of Synaptotagmin Location and Function

...tosis. The addition of the phorbol ester PMA, which potentiates insulin exocytosis distal to the increase of cytosolic Ca 2+ showed that both proteins are directly involved in the Ca 2+ -dependent stimulation of exocytosis. Th...
Cytosolic in Biological Products

PhosphoSafe Extraction Buffer from Novagen

Description:... PhosphoSafe Extraction Reagent extracts cytosolic proteins from mammalian and insect cells while preserving their phosphorylation state. The reagent, an enhancement of the CytoBuster Protein Extractio...
Company:Novagen

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...able isotope dilution mass spectrometry. 5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the m...
Company:Cayman Chemical

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...able isotope dilution mass spectrometry. 5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the m...
Company:Cayman Chemical

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...able isotope dilution mass spectrometry. 5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the m...
Company:Cayman Chemical

Rabbit Anti-Human XM_941015 Polyclonal Antibody, Unconjugated from Proteintech Group, Inc.

Description:... Homo sapiens similar to cytosolic acyl coenzyme A thioester hydrolase Antigen: Peptide...
Company:Proteintech Group, Inc.

Qproteome Nuclear Subfractionation Kit from QIAGEN

Description:... For separation and fractionation of nucleic-acid binding proteins Efficient separation of nuclei from cytosolic proteins A huge reduction in sample complexity, greatly facilitating study of low-abundance nuclear proteins Subfractionation of nucleic acid binding ...
Company:QIAGEN
Cytosolic in Biological Definition

Cell growth

...Typical stem cells reproduce, double in size, then reproduce again. Most cytosolic contents such as the endomembrane system and the cytoplasm easily scal...om the mother's body. Their large size can be achieved either by pumping in cytosolic components from adjacent cells through cytoplasmic bridges ( Drosophila ) o...

Cytosol

...plast or the cell wall (if present), are used to counteract the osmotic pressure. Details The cytosol is 20% to 30% protein . Normal human cytosolic pH is (roughly) 7.0 (i.e. neutral), whereas the pH of the extracellular fluid is 7.4. ...

Major histocompatibility complex

...rphic domains, α 1 , α 2 , which present peptides derived from cytosolic proteins to the immune system. The peptides are short, consisting of 8-10...resented by class II molecules are derived from extracellular proteins (not cytosolic as in class I). Loading of class II molecules must still occur inside the ...

Signal transduction

... 2+ upon interaction with inositol triphosphate (thus the name) on its cytosolic side. It consists of four identical subunits. The ryanodine-receptor ...ated to transport Ca 2+ into the cytosol by recognizing Ca 2+ on its cytosolic side , thus establishing a feedback mechanism; a small amount of Ca 2+ i...

Vesicle

...he same as that of the outer (cellular) membrane. Thus, because of the separation, the intravesicular environment can be made to be different from the cytosolic environment. Vesicles are a basic tool of the cell for organizing metabolism , transport, enzyme storage, as well as being chemical reaction chamb...
Cytosolic in Biological Dictionary

NADPH

... transfers (as single nucleotide ATP, GTP, and double nucleotide NADH and NADPH ) ... THE PMN NADPH OXIDASE... THE MEMBRANE COMPONENTS OF... cytosolic COMPONENTS OF THE... The NADPH oxidase, comprised of membrane [gp91phox (where phox stands for ... ... nature of these nonphagocyte NADPH oxida...

Glycolipid

...th on the pencil line. ... of the TLC plate containing the glycolipid standards. ... The European ... Glycolipid transfer protein (GLTP) is a cytosolic protein ... for adaptive ligand binding of glycolipid transfer protein. J. Mol. ... A team led by biologists at the University of California, S...

Gene product

... among a list of ... to provide a common language to describe aspects of a gene product's biology. ... A major regulatory gene product is a cytosolic receptor to which radiolabeled 2, ... A Bacillus subtilis regulatory gene product for genetic competence and ... AB1761 Rabbit x Protein Gen...
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(Date:7/9/2014)... type of lung cancer, researchers have uncovered mutations in ... tumors. The new knowledge may expand treatments for patients ... are available or are in clinical trials. , Reporting ... Cancer Genome Atlas (TCGA), including researchers at Washington University ... and other institutions, studied tumors from 230 patients with ...
(Date:7/9/2014)... -- Researchers from The Miriam Hospital have ... (COPD) who are also depressed have difficulty sticking ... be particularly true for women, and screening and ... part of treatment. The study and its findings ... . , Chronic obstructive pulmonary disease is ...
(Date:7/9/2014)... KNOXVILLEAmphibian declines and extinctions around the world have ... chytridiomycosis, but new research from the National Institute ... another pathogen, ranavirus, may also contribute. , ... that ranavirus, which causes severe hemorrhage of internal ... populations of wood frogs if they are exposed ...
(Date:7/9/2014)... retrospective study conducted by researchers at Tufts University School ... with intellectual and developmental disabilities, the likelihood of having ... care increased. The findings, published in the July/August issue ... improve interventions designed to address the oral health of ... the dental records of 107 patients at one of ...
(Date:7/9/2014)... allergic diseases has risen dramatically in Western societies. One ... to microorganisms and have fewer infections than previous generations, ... study by researchers at Sahlgrenska Academy, University of Gothenburg, ... maturation of the immune system in relation to allergic ... of the Vstra Gtaland Region, half of them on ...
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(Date:7/9/2014)... may be on the verge of an economy driven by ... than coal and is undergoing a production boom. It has ... recent research is casting serious doubts over just how climate-friendly ... Engineering News (C&EN), the weekly news magazine of the ... senior correspondent at C&EN, explains that when burned as a ...
(Date:7/9/2014)... Cholinergic inhibitors and N-methyl-D-aspartate receptor antagonists can ... fail to affect irreversible cognitive dysfunction and ... brain. Amyloid beta peptide (Aβ) vaccines reduced ... disease (AD) transgenic mouse model, and significantly ... Cao and his team, First Affiliated Hospital ...
(Date:7/9/2014)... data can yield big savings, if they are ... Bates of the Brigham and Women,s Hospital and ... for cost savingshigh-cost patients; readmissions; triage; decompensation (when ... optimization when a disease affects multiple organ systems. ... though the current costs associated with all six ...
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