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Cytoplasmic in Medical News

Early treatment of systemic onset JIA with anakinra restores the IL-18 response

...nt of the innate immune system. NK cells play a major role in the rejection of tumors and cells infected by viruses. The cells kill by releasing small cytoplasmic granules of proteins called perforin and granzyme that cause the target cell to die by apoptosis or necrosis. ...

Jefferson researchers identify critical marker of response to gemcitabine in pancreatic cancer

...d pancreatic cancer patients who received gemcitabine, patients who had low cytoplasmic HuR levels had a 7-fold increased mortality risk compared to patients with ... more efficient, according to Dr. Brody. "Normally, patients higher HuR cytoplasmic levels have a worse prognosis, since HuR expression is associated with adva...

Long-term L-carnitine supplementation prevents development of liver cancer

...ous dietary sources such as red meat and dairy products. L-carnitine is an essential cofactor for the translocation of long chain fatty acids from the cytoplasmic compartment into mitochondria, where beta-oxidation enzymes are located for ATP production. Despite the liver being the main organ responsible for end...

Seahorse XF96 Extracellular Flux Analyzer Wins Best New Product Award for DRUG DISCOVERY at 2009 Molecular Medicine Conference

...unced today that the XF96 Extracellular Flux Analyzer, the first analytical instrument for the kinetic measure of mitochondrial oxygen consumption and cytoplasmic glycolysis in a 96-well microplate, was selected as the Best New Product for Drug Discovery Assays & Kits by researchers at the Molecular Medicine...

Best New Product Awards Winners Named at Molecular Medicine Tri-Conference

...lular Flux Analyzer The Seahorse XF96 Analyzer is the first analytical instrument for the kinetic measurement of mitochondrial oxygen consumption and cytoplasmic glycolysis in a 96-well microplate. The easy-to-use instrument assays cells in minutes, using a label-free, non-destructive method. Measure mitochon...

Varicella zoster infection causes severe autoimmune hepatitis

...Anti-nuclear, anti-smooth muscle, anti-mitochondrial and antiliver/kidney microsomes (ALKM-1) autoantibodies were negative. Perinuclear antineutrophil cytoplasmic antibodies were positive. Hepatitis B surface antigen, anti-hepatitis B core antigen IgM, anti-hepatitis C virus antibodies, anticytomegalovirus (CMV)...
Cytoplasmic in Medical Products

Purkinje Cell Cytoplasmic Antibody (PCCA), IFA & WB, CSF

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Purkinje Cell Cytoplasmic Antibody by IFA with Reflex to Titer & Immunoblot

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Anti-Neutrophil Cytoplasmic Antibody with Reflex to Titer & MPO/PR3 Antibodies

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Anti-Neutrophil Cytoplasmic Antibody, IgG

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Anti-Neutrophil Cytoplasmic Antibodies Panel, IgG

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

ImmuGlo COMVI-ANCA (ethanol+formalin fixed)

Description:... An indirect immunofluorescence antibody test for the detection and semi-quantitation of anti-neutrophil cytoplasmic antibodies (ANCA) in human serum. ANCA are found in the sera of patients with necrotizing vasculitides and hence, serve as an aid to the clinical and ...
Company:IMMCO Diagnostics
Cytoplasmic in Medical Dictionary

Vesicle

...dependently of MAPK activation, leading us to ... activation is essential for germinal vesicle breakdown (GVBD) in all species, ... GO:0030659 : cytoplasmic vesicle membrane [391 gene products] ... GO:0030120 : vesicle coat [200 ... GO:0030136 : clathrin-coated vesicle [441 gene products] ... ...

Thrombocyte

... of nonmammalian vertebrates that promotes blood clotting ... is a thrombocyte not a natural ... platelet n. A minute, nonnucleated, disklike cytoplasmic body found in the blood plasma of ... thrombocyte . What does platelet blood look like? Read answer... thrombocyte synonyms. thrombocy...

Sterility

...ery indicates a micro-environment (the surgical ... "http://en.wikipedia.org /wiki/ Sterility " Categories: Disambiguation pages ... cytoplasmic male sterility is the total or partial male sterility associated with plant biology as the result of specific nuclear and mitochondrial interact...

Platelet

...ount is ordered, and what the results might mean ... If platelet levels fall below 20,000 per ... platelet n. A minute, nonnucleated, disklike cytoplasmic body found in the blood plasma of mammals that is derived from a megakaryocyte and More about Platelet Count: Purpose Aftercare Risks Normal...

Membrane

...rane n. The semipermeable membrane that encloses the cytoplasm of a cell. ... During endocytosis the membrane maintains its orientation, with its cytoplasmic ... The increased knowledge of the molecular basis of neurobiology will ultimately lead to an understanding of the coding of experiences that co...

Infertility

...g schedules. ... Dr. Sherman J. Silber offers infertility treatments including vasectomy reversals, in vitro fertilization (IVF) and intra cytoplasmic sperm injection (ICSI) Usually, a couple doesn't realize they are dealing with infertility until after unsuccessfully trying to get pregnant...
Cytoplasmic in Biological News

Scientists sequence genome of the N2-fixing, soil-living bacterium Azotobacter vinelandii

...aerobic metabolism. A. vinelandii has one of the highest respiratory rates of any known bacterium and has the capacity to maintain low levels of cytoplasmic oxygen through a process called respiratory protection. The sequence of the bacteria's genome allowed the team of researchers to identify the genes in...

New study overturns orthodoxy on how macrophages kill bacteria

...lauch said. In contrast, deleting the gene encoding the periplasmic superoxide dismutase, SodC, conferred the same defect regardless of whether the cytoplasmic SodA/SodB were present or absent, showing that its function is independent of the cytoplasm. Moreover, strains lacking SodC were impaired only in t...

Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals

... will enhance effectiveness in treatment. Previous immunohistochemical and immunoelectron microscope studies have detected OGF and OGFr in both the cytoplasmic and the nuclear compartments. The OGF-OGFr axis is known to regulate cell proliferation by modulating cyclin dependent kinase inhibitors, resulting i...

Research yields potential target for cancer, wound healing and fibrosis

... that may help scientists design novel approaches to control wound healing and fight diseases such as cancer and fibrosis. The paper, β1 Integrin cytoplasmic Domain Residues Selectively Modulate Fibronectin Matrix Assembly and Cell Spreading through Talin and Akt-1, will be published in the March 20, 2009 i...

Jefferson scientists discover a key protein regulator of inflammation and cell death

...sent in melanoma 2), is involved in the detection and reaction to dangerous cytoplasmic DNA that is produced by infection with viral or microbial pathogens, or by ...he invading pathogen. When AIM2 binds to the foreign DNA, it recruits a cytoplasmic protein called ASC. ASC and AIM2 then work together to activate caspase-1, ...

Mutant host cell protein sequesters critical HIV-1 element

...present in the cytoplasm, suggesting that it may serve some function in the cytoplasmic stage of the HIV-1 life cycle. The ability of the Sam68 cytoplasmic mutant to interfere with Nef correlated with its ability to induce stress g...
Cytoplasmic in Biological Technology

LIVE/DEAD Viability/Cytotoxicity Assay for Animal Cells Using the SpectraMax Gemini XS Fluorescence Microplate Reader (MaxLine Application Note #43)

.... Cal AM is an electrically neutral, nonfluorescent, esterase substrate that diffuses into live cells and becomes enzymatically cleaved by ubiquitous cytoplasmic esterases. This releases the free calcein fluorophore that is retained inside live cells. The dye emits a strong green fluorescence that peaks at ~525...

Performance of Ad-A-Gene EGFP-MAPKAP-k2: an adenoviral vector gene delivery system

...mic (nuc/cyt) ratio is the population-averaged ratio of sampled nuclear and cytoplasmic intensities measured in the EGFP signal channel.

† Time-co...8 h after transduction with the EGFP-MAPKAP-k2 adenoviral vector at 50 MOI. cytoplasmic translocation of EGFP-MAPKAP-k2 was observed following treatment with 300-n...

The measurement of DNA condensation and mitochondrial changes during apoptosis and necrosis in cell based assays

... granularity algorithm of the IN Cell Analyzer 3000 in both the nuclear and cytoplasmic compartments.

The protocol provided allows nuclear change...nularity Analysis Module is applied sequentially to analyze the nuclear and cytoplasmic staining. This module automatically defines measurement areas of interest s...

Performance of Ad-A-Gene EGFP-Glucocorticoid Receptor (EGFP-GCCR): an adenoviral vector gene delivery system

...mic (Nuc/Cyt) ratio is the population-averaged ratio of sampled nuclear and cytoplasmic intensities measured in the EGFP signal channel.

* Time-controll...cies of transduction into a broad range of target cell types. The EGFP-GCCR cytoplasmic to nuclear translocation was stimulated by treatment with 200-nM dexamethas...

Sample Preparation Solutions for Cellular Protein Fractionation Poster, Rev A

...ghly enriched protein fractions based on protein solubility. One protocol separates a complex sample into enriched fractions of nuclear and cytoplasmic proteins. A second protocol enriches for membrane-associated signaling proteins. Other protocols enrich for membrane proteins. A...

Separation and Comparison of Proteins From Virulent and Nonvirulent Strains of the Fish Pathogen Flavobacterium psychrophilum, Using a 2-D Electrophoretic Approach

...ns To identify hydrophilic (primarily cytoplasmic nonmembrane proteins) and hydrophobic p...ure to isolate proteins associated with cytoplasmic or cell membrane compartments of the ba... extraction kit allowed cell-associated and cytoplasmic proteins to be effectively separated. I...
Cytoplasmic in Biological Products

Mouse Anti-Human Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4) Monoclonal Antibody, Unconjugated from Lifespan Biosciences

Description: Mouse Anti-Human Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4 Monoclonal Antibody Family: New...
Company:Lifespan Biosciences

Anti-Connexin 45 (Cx45), Near C-terminus, cytoplasmic Monoclonal Antibody, Unconjugated, Clone 5B9.2 from CHEMICON

Description: Recognizes Human Connexin 45. Due to sequence homologies, this antibody is also expected to react with canine (100% homology) and mouse (92% homology) Connexin 45. Also confirmed to work on rat C6 cells. Others not tested....
Company:CHEMICON

Mouse Anti-Human Killer Cell Immunoglobulin-like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2 (KIR2DL3) Monoclonal Antibody, Unconjugated from Lifespan Biosciences

Description: Mouse Anti-Human Killer Cell Immunoglobulin-like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2 (KIR2DL3 Monoclonal Antibody Family: Immunoglobulin Sub-Family: not assigned-Immunoglobulin Applications: Flow Cytometry...
Company:Lifespan Biosciences

eBioscience IC Fixation Buffer 125 ml from eBioscience

Description:...ermeabilization Buffer (Cat. No. 00-8333), can be used to fix and permeabilize cells prior to performing intracellular staining of cytokines and other cytoplasmic and/or nuclear antigens. These solutions have been specially formulated for reducing non-specific staining by fluorochrome-labelled antibodies and inc...
Company:eBioscience

CCF4-AM from Invitrogen

Description:...negatively charged fluorescent beta-lactamase substrates, CCF2 and CCF4. These lipophilic esters readily enter the cell, where cleavage by endogeneous cytoplasmic esterases rapidly converts them into their negatively charged forms, thereby trapping them in the cytosol....
Company:Invitrogen

CCF4-AM from Invitrogen

Description:...negatively charged fluorescent beta-lactamase substrates, CCF2 and CCF4. These lipophilic esters readily enter the cell, where cleavage by endogeneous cytoplasmic esterases rapidly converts them into their negatively charged forms, thereby trapping them in the cytosol....
Company:Invitrogen
Cytoplasmic in Biological Definition

Actin

...echanical support for the cell, determine the cell shape, enable cell movements (through pseudopods ); and participate in certain cell junctions, in cytoplasmic streaming and in contraction of the cell during cytokinesis . In muscle cells they play an essential role, along with myosin , in muscle contrac...

Cell growth

...opment takes place away from the mother's body. Their large size can be achieved either by pumping in cytosolic components from adjacent cells through cytoplasmic bridges ( Drosophila ) or by internalization of nutrient storage granules (yolk granules) by endocytosis ( frogs ). Increases in the size of plan...

Dynein

...is involved in their reproduction. Dyneins can be divided into two groups: cytoplasmic dynein and axonemal dynein. The axonemal dynein acts to activate a sliding within flagellar microtubules , whereas the cytoplasmic dynein is implicated in moving toward the negative end of a microtubule. ...

Epigenetics

...hanisms, which include differences in DNA methylation , as well as difference in chromatin structure. Another possibility involves the genomes of cytoplasmic elements ( chloroplasts and mitochondria ). Other mechanisms have also been proposed. See epigenetic inheritance for a more detailed discussion. ...

Lysozyme

...mmonly referred to as the "body's own antibiotic ". It is abundantly present in a number of secretions , such as tears . This protein is present in cytoplasmic granules of the polymorphonuclear neutrophils (PMN) and released to the mucosal secretions. This enzyme functions by attacking peptidoglycan by ...

Actin

...echanical support for the cell, determine the cell shape, enable cell movements (through pseudopods ); and participate in certain cell junctions, in cytoplasmic streaming and in contraction of the cell during cytokinesis . In muscle cells they play an essential role, along with myosin , in muscle contrac...
Cytoplasmic in Biological Dictionary

Vesicle

...listen to free streaming mp3s, & read Vesicle's blog. GO:0016023 : cytoplasmic membrane-bounded vesicle [14310 gene products] ... GO:0030136 : clathrin-coated vesicle [396 gene products] ... GO:0030659 : cytoplasmic vesicle membrane [391 gene products] ... GO:0030120 : vesicle coat [2...

Transport protein

...ns Vesicles Carrier Protein Transport Cytoskeleton Microtubles Animation ... TransportDB is a relational database describing the predicted cytoplasmic membrane transport protein complement for organisms whose complete genome sequence are ... The transport protein molecules that arriv...

Spermatogenesis

... ... Spermatogenesis is the process of producing sperm with half the number of ... This part of spermatogenesis is defined as the nuclear and cytoplasmic changes ... The major players that regulate mammalian spermatogenesis are: ... The requirement for BMP8b for spermatogenesis has been demonstra...

Prophase

...nses into thick strands that eventually become ... Photos of the process of cell division. ... During prophase , the cytoskeleton (composed of cytoplasmic microtubules) begins ... Late Prophase ... In prophase the replicated, linked DNA strands slowly wrap... Genetics: stages of mitosis ... Pro...

Polyadenylation

...ole of polyadenylation in activating c-mos mRNA differs from its role ... cytoplasmic polyadenylation is often correlated with, and can cause, ... This proc... the polyadenylation of mRNA until the MII stage ... and mouse oocytes, cytoplasmic polyadenylation and sequential translation of ... ...

Pinocytosis

...nocytosis : The cellular process of actively engulfing ... Pinocytosis . Pinocytosis is the ingestion of dissolved materials by endocytosis. The cytoplasmic membrane invaginates and pinches off placing small droplets of ... Get information, facts, and pictures about pinocytosis at Encyclopedia.com. .....
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