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Cytomegalovirus in Medical News

Cell death from cytomegalovirus may bring new life to treatment of retinal disease

AUGUSTA, Ga. Just days after the first retinal cell gets infected with the common cytomegalovirus, contiguous cells start committing suicide and researchers believe their death may provide clues to better treatment of this potentially blinding infection. Understanding the cell death may also p...

Innovative Method for Creating a Human Cytomegalovirus Vaccine Outlined

Each year, about 40,000 children are born infected with human cytomegalovirus, or CMV, and about 8,000 of these children suffer permanent disabilities due to the virus – almost one an hour. These disabilities// can include hearing loss, vision loss, mental disability, a lack of coordination, and se...

Creation of Cytomegalovirus Vaccine by an Innovative Method

Human cytomegalovirus, or CMV infects about 40,000 children before birth and about 8,000 of these children suffer permanent disabilities due to the virus – almost one an hour.// Such disabilities can include vision loss, hearing loss, mental disability, a lack of coordination, and seizures. Acc...

ViroPharma Announces Initiation Of Non-Toxigenic Clostridium Difficile Phase 1 Program

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE, and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the i...

ViroPharma Announces Support by Advisory Committee of The Office of Generic Drugs Proposed Guidelines for Developing Generic Versions of Oral Vancomycin Hydorchloride

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. diff . ViroPharma routinely posts information, including press releases, which may be important to investors in the investor...

ViroPharma Incorporated Reports Second Quarter 2009 Financial Results

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the in...

ViroPharma to Release 2009 Second Quarter Financial Results on July 29, 2009

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the ...

3 studies confirm the value of etanercept therapy in treating juvenile idiopathic arthritis

...w-up, and the ACR Pedi 70 response was reached by 48% and 73% respectively. Four patients (12%) developed mild adverse events: including one case of cytomegalovirus infection and three varicella zoster virus (VZV) infections. One patient experienced a serious adverse event and was hospitalised for a necrotising fa...

ViroPharma Announces Appointment of Frank Baldino, Jr., Ph.D. to Board of Directors

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the inve...

ViroPharma Announces Meeting of FDA Advisory Committee for Pharmaceutical Science and Clinical Pharmacology on Bioequivalence Recommendations for Oral Vancomycin Hydrochloride Products

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the inve...
Cytomegalovirus in Medical Technology

IMPACT Study Showed Longer Valcyte(R) (valganciclovir hydrochloride tablets) Treatment Demonstrated Better Protection Against Cytomegalovirus (CMV) Disease One Year Post-Transplant

CMV is the most serious viral infection affecting transplant patients BOSTON, June 1 /PRNewswire/ -- New Phase III study results presented for the first time today at the ninth annual American Transplant Congress 2009 (ATC) demonstrate that doubling the duration of preventive therapy ('prop...

Scientific Data Relating to Cinryze(TM) Presented at 6th Annual C1 Inhibitor Deficiency Workshop

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the inve...

ViroPharma Submits Comments on Vancocin(R) Draft Bioequivalence Guidance

... the package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the inve...

ViroPharma Announces Discontinuation of Maribavir Phase 3 Study in Liver Transplant Patients

...l evaluating maribavir used as prophylaxis against cytomegalovirus (CMV) disease in liver transplant patients has bee...ral drug with a unique mechanism of action against cytomegalovirus and a favorable clinical safety profile to date, i...istant to current anti-CMV therapies. About cytomegalovirus CMV is a member of the herpes virus group, whic...

FDA Grants Priority Review of a Supplemental Biologics License Application for Cinryze(TM) C1 Inhibitor (Human) as Treatment for Acute Attacks of Hereditary Angioedema (HAE)

... the package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the inve...

Three Studies Presented at the American Society of Hematology Annual Meeting Showed Response to Treatment with Campath(R) in Patients with High-Risk CLL

...roup treated with FCR. There was no significant difference in incidence of infection during treatment with CFAR compared to FCR, with the exception of cytomegalovirus (CMV) reactivation. Follow-up continues for the patients treated on this trial to evaluate responses in all 60 enrolled patients and time-to-event end...

Vical Completes Enrollment and Reports Positive Interim Data in CMV Vaccine Phase 2 Trial

...jects in a Phase 2 trial of its therapeutic DNA vaccine designed to prevent cytomegalovirus (CMV) reactivation and disease in immunosuppressed stem cell transplant rec...e these forward-looking statements. (1) Avetisyan G, et al. Impact on the cytomegalovirus (CMV) viral load by CMV-specific T-cell immunity in recipients of allogenei...

CMV Disease in Stem Cell Transplantation: Prevention and Drug Resistance

... A Complimentary Continuing Education Activity VOORHEES, N.J., Aug. 14 /PRNewswire/ -- cytomegalovirus (CMV) is a significant cause of morbidity and mortality in recipients of hematopoietic stem cell transplantation. The clinical manifestations of CMV d...

Promise of Vical's CMV Vaccine Noted by Independent Experts

...t issue of The Journal of Infectious Diseases (JID), independent experts on cytomegalovirus (CMV) said the vaccine under development by Vical Incorporated (Nasdaq: VI...ation to update these forward-looking statements. (1) Go V, Pollard RB. A cytomegalovirus Vaccine for Transplantation: Are We Closer? J Infect Dis 2008; ( http://www...

ViroPharma Announces Completion of Enrollment in Phase 3 Study of Maribavir in Stem Cell Transplant Patients

...tudy is evaluating the efficacy, safety and tolerability of prophylactic use of maribavir administered orally for up to 12 weeks for the prevention of cytomegalovirus (CMV) disease in recipients of allogeneic stem cell transplants (SCT). The study also will evaluate the pharmacokinetics of maribavir in this subject ...
Cytomegalovirus in Medical Products

Viral Culture & Cytomegalovirus Culture

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

ImmunoDOT Mono M Test

Description:...est is a qualitative enzyme immunoassay (EIA) that detects IgM antibodies to Paul-Bunnell heterophil, Epstein-Barr virus capsid antigen (EBV-VCA), and cytomegalovirus (CMV). When used in conjunction with Mono-G Test, it is an aid in the serodiagnosis of infectious (EBV) mononucleosis and presumptive serodiagnosis of...
Company:GenBio

ImmunoDOT Mono G Test

Description:...ve enzyme immunoassay (EIA) that detects IgG antibodies to Epstein-Barr virus capsid antigen (EBV-VCA), Epstein-Barr early nuclear antigen (EBV-EBNA), cytomegalovirus (CMV), and Toxoplasma. When used in conjunction with Mono-M Test it is an aid in the serodiagnosis of infectious (EBV) mononucleosis and presumptive s...
Company:GenBio

ImmunoDOT TORCH Test

Description:...ImmunoDOT TORCH Test is an enzyme immunoassay (EIA) procedure intended for determining the presence of antibodies to Toxoplasma gondii, rubella virus, cytomegalovirus and herpes simplex virus in serum and heparinized whole blood to indicate previous or current infection by these agents....
Company:GenBio

PK7200® Automated Microplate System

Description:...e agglutination technology. Its is a fully automated blood testing system for donor ABO/Rh testing. PK7200 also handles weak D as well as syphilis and cytomegalovirus antibody detection. The Automated Microplate System delivers the very latest technology along with the proven reliability that for the past generation...
Company:Olympus America Diagnostics

Viroclear ToRCH

Description:...ibodies to Toxoplasma gondii (TOXO IgG and TOXO IgM), IgG and IgM antibodies to rubella virus (rubella IgG and rubella IgM), IgG and IgM antibodies to cytomegalovirus (CMV IgG and IgM), and IgG and IgM antibodies to herpes simplex virus types 1 and 2 (HSV-1 IgG, HSV-1 IgM, HSV-2 IgG and HSV-2 IgM)....
Company:Blackhawk BioSystems, Inc.

Virotrol® ToRCH-M

Description:...ibodies to Toxoplasma gondii (TOXO IgG and TOXO IgM), IgG and IgM antibodies to rubella virus (rubella IgG and rubella IgM), IgG and IgM antibodies to cytomegalovirus (CMV IgG and CMV IgM), and IgG antibodies to herpes simplex virus types 1 and 2 (HSV-1 IgG and HSV-2 IgG)....
Company:Blackhawk BioSystems, Inc.

Viroclear® ToRCH

Description:...ibodies to Toxoplasma gondii (TOXO IgG and TOXO IgM), IgG and IgM antibodies to rubella virus (rubella IgG and rubella IgM), IgG and IgM antibodies to cytomegalovirus (CMV IgG and IgM), and IgG and IgM antibodies to herpes simplex virus types 1 and 2 (HSV-1 IgG, HSV-1 IgM, HSV-2 IgG and HSV-2 IgM)....
Company:Blackhawk BioSystems, Inc.

Virotrol® ToRCH

Description:...ality assurance reagent in assays detecting IgG antibody to Toxoplasma gondii (TOXO IgG), IgG antibody to rubella virus (rubella IgG), IgG antibody to cytomegalovirus (CMV IgG) and IgG antibody to herpes simplex virus types 1 and 2 (HSV-1 IgG and HSV-2 IgG)....
Company:Blackhawk BioSystems, Inc.

Virotrol® I

Description:...uman T-lymphotropic virus type I (anti-HTLV-I), antibody to hepatitis C virus (anti-HCV), antibody to hepatitis B core antigen (anti-HBc), antibody to cytomegalovirus (anti-CMV), and hepatitis B surface antigen (HBsAg)....
Company:Blackhawk BioSystems, Inc.

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Cytomegalovirus in Medical Dictionary

Cytomegalovirus

Cytomegalovirus is a herpes viral genus of the Herpesviruses group: in humans it is commonly known as HCMV or Human Herpesvirus 5 (HHV-5). CMV belongs to the Betaherpesvirinae subfamily of Herpesviridae, which also includes... From the Centers for Disease Control. Includes at risk populat...

Retinitis

... Retinitis (Chorioretinitis, cytomegalovirus retinitis ) · Retinal detachment ... Retrieved ...e about Retinitis pigmentosa. Diagnostic ... cytomegalovirus (CMV) Retinitis ... Untreated, CMV retinitis l...entosa International publishes a quarterly ... cytomegalovirus (CMV) retinitis is a viral inflammation of t...

Monocyte

...monocyte chemotactic protein-1 secretion in human ... Monocyte -derived macrophages (MDMs) play a central role in the pathogenesis of ... Human cytomegalovirus infection of the monocyte /macrophage lineage in bone marrow. ... Monocyte - Definition of Monocyte at Dictionary.com a free online dictio...

Intestinal Diseases

...ats. Overall ... Common Cold, Congenital Infections, Conjunctivitis, Coxsackieviruses and Other Enteroviruses, Creutzfeldt-Jakob Disease , Croup, cytomegalovirus (CMV) Infection, ... Diseases of the digestive system are ... DISEASES OF THE SALIVARY GLANDS ... usually diseases that thicken, block or de...

Creutzfeldt-Jakob Disease

...her transmissible agents. ... Creutzfeldt - Jakob Disease Information ... Creutzfeldt - Jakob Disease (CJD) Cryptosporidiosis. Cyclospora. cytomegalovirus (CMV) ... Few people had even heard of Creutzfeldt - Jakob disease until the mid-1990s. At ... Disorders and Stroke (NINDS): Creutzfeldt - Ja...

CMV retinitis

... cytomegalovirus retinitis , also known as CMV retinitis , is an ...ed through a standard ophthalmologic exam. ... cytomegalovirus ( CMV ) retinitis is a viral inflammation of...show signs of CMV retinitis . ... Overview: cytomegalovirus ( CMV ) is a ubiquitous DNA virus that infects t...
Cytomegalovirus in Biological News

LIAI scientists make important finding on cytomegalovirus transmission

Researchers at the La Jolla Institute for Allergy & Immunology have shown that cytomegalovirus (CMV) in the salivary glands can be reduced ?and in some cases eliminated ?through the use of antibodies to enhance the disease-fighting power of the immune system. The research team’s findings, base...

Innovative method for creating a human cytomegalovirus vaccine outlined

Each year, about 40,000 children are born infected with human cytomegalovirus, or CMV, and about 8,000 of these children suffer permanent disabilities due to the virus ?almost one an hour. These disabilities can include hearing loss, vision loss, mental disability, a lack of coordination, and seizu...

UCSF researchers identify new drug target for Kaposi's sarcoma

...family. "All known herpes virus proteases are structurally similar," Craik explained. "The inhibitor we found knocks out not only KS, but also the cytomegalovirus protease, so the site we've identified here could be a target for a broad-acting inhibitor against the entire viral family." To their knowledge, th...

Nature Medicine study shows Peregrine's bavituximab can cure lethal virus infections

...ism program of the U.S. Defense Threat Reduction Agency (DTRA). Bavituximab and other anti-PS antibodies are also being studied preclinically in HIV, cytomegalovirus (CMV) and other serious viral infections. "Based on these findings, anti-PS antibodies such as bavituximab may represent a completely new class o...

Caltech biologists spy on the secret inner life of a cell

... laboratory studies how the immune system recognizes its targets, work that is offering insight into the processes by which viruses like HIV and human cytomegalovirus invade cells and cause disease. The electron tomography images revealed that the FcRn/antibody complexes were collected within cells inside large v...

Virus weaves itself into the DNA transferred from parents to babies

...r it produces any developmental or immune system problems. Some congenital infections can cause serious problems in fetuses. If a mother contracts cytomegalovirus (CMV) while pregnant, her fetus is at risk of hearing or vision loss, developmental disabilities and problems with the lungs, liver and spleen. Some o...

CMV infections affect more than just patients with compromised immune systems, researchers find

... An infection due to a virus called cytomegalovirus (CMV), which most commonly affects people with compromised immune systems, can also affect hospital intensive-care patients who have no immune-system ...

A viral cloaking device

...e in a continual dance for survival--viruses ever seek new ways to evade detection, and our immune system devises new methods to hunt them down. Human cytomegalovirus (HCMV), says Bjorkman, Caltech's Delbrck Professor of Biology and a Howard Hughes Medical Institute (HHMI) Investigator, "is the definition of a succe...

BWF awards $7 million to infectious disease investigators

... modulation of bacterial group activities Dong Yu, Ph.D. Washington University School of Medicine Modulation of the DNA damage response by human cytomegalovirus ...

New vaccine prevents CMV infection and disease in mice

...an Diego (UCSD) Skaggs School of Pharmacy and Pharmaceutical Sciences have patented a strategy for developing a human vaccine to prevent against Human cytomegalovirus (hCMV) infection and disease. CMV, a type of herpes virus, is the leading viral cause of birth defects and a serious problem in patients with comp...
Cytomegalovirus in Biological Technology

Chimerix, Inc. Appoints Kenneth I. Moch Chief Operating Officer

...ociated with smallpox vaccination, as well as for the treatment of infections that cause morbidity and mortality in immunocompromised patients such as cytomegalovirus (CMV) and BK virus. Chimerix's pipeline includes an anti-HIV drug, CMX157, in late-stage preclinical studies. Chimerix is also advancing programs in...

ViroPharma Receives Complete Response Letter for Cinryze(TM) Supplemental Biologics License Application for Acute Treatment of Hereditary Angioedema

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the inve...

ViroPharma to Present at Two June Healthcare Conferences

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the inve...

ViroPharma Incorporated Honored by the National Organization for Rare Disorders

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the inve...

ViroPharma Incorporated Reports First Quarter 2009 Financial Results

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the inve...

ViroPharma to Release 2009 First Quarter Financial Results on April 29, 2009

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the inve...

ViroPharma Improves Financial Position Through Repurchase of $45 Million Principal Amount of Senior Convertible Notes

... the package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile. ViroPharma routinely posts information, including press releases, which may be important to investors in the inve...

Nature Medicine study shows Peregrine's bavituximab can cure lethal virus infections

...ism program of the U.S. Defense Threat Reduction Agency (DTRA). Bavituximab and other anti-PS antibodies are also being studied preclinically in HIV, cytomegalovirus (CMV) and other serious viral infections. "Based on these findings, anti-PS antibodies such as bavituximab may represent a completely new class o...

ViroPharma Incorporated Reports Fourth Quarter and Full Year 2008 Financial Results

...Discontinued maribavir clinical development program for prophylaxis against cytomegalovirus disease in transplant patients based on the preliminary analysis of phase 3...rma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile. ViroPharma routinely posts information, ...

Chimerix Completes Phase I Study and Initiates a Phase II Multi-dose Clinical Trial for CMX001

...lead to loss of the kidney graft, or to uncontrolled bleeding in the bladder. Further studies are planned to explore the ability of CMX001 to prevent cytomegalovirus disease, a viral disease that may lead to blindness or severe gastrointestinal disease after bone marrow transplant. CMX001 is being developed ...
Cytomegalovirus in Biological Products

LIGHT DIAGNOSTICS™ CMV pp65 Dextran Leukocyte Separation Kit, included in kit #3247 from CHEMICON

Description:... The Light Diagnostics cytomegalovirus (CMV) pp65 Antigenemia Immunofluorescence Assay (IFA) is intended for the qualitative identification of lower matrix protein pp65 of CMV in isolated p...
Company:CHEMICON
Cytomegalovirus in Biological Dictionary

Nuclear lamina

...roughout the ... Given that the nuclear lamina potentially excludes nucleocapsids from ... Remodelling of the nuclear lamina during human cytomegalovirus infection: role ... The main components of the nuclear lamina are the lamins, which, based on their ... The nuclear lamina represents a sev...
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