Navigation Links
Cytokine in Medical News

Do bacterial combinations result in enhanced cytokine production? No!

Probiotic bacteria, defined as living microorganisms that have beneficial effects on human health, have been used for the prevention and treatment of a diverse range of disorders. However, the ways in which probiotic bacteria elicit their health effects are not fully understood. One of the action ...

Experimental Drug Causes Cytokine Storm

A clinical trail with an experimental drug designed to treat chronic inflammatory conditions and leukemia resulted in an immune system overreaction leading// to six British men involved in the trail becoming seriously ill. All the six men have since recovered from the drug reaction. Dr. Gane...

Avipaxin Is First Entrant in Medical Arsenal for Neuro-Endocrine-Immune Connection(C) Product and Testing Protocols

...I) Connection(C). Elevated pro-inflammatory cytokine levels lead to imbalances in neurotransmitter conc...ith mood and sleep. Research shows that persistent cytokine elevations lead to numerous physical and emotional...cult to manage. Avipaxin modulates elevated cytokine levels by supporting acetylcholine-mediated signal...

Study identifies biomarker that safely monitors tumor response to new brain cancer treatment

...brain tumors go undetected and proliferate rapidly. In the technique devised by Castro and Lowenstein, one of the proteins (the immune stimulatory cytokine Flt3L) attracts dendritic cells from bone marrow into the tumor while another protein (thymidine kinase) and the antiviral drug gancyclovir combine to...

Rare disorder gives modelers first glimpse at immune system development

...As transplanted thymus tissue took hold in the children, the team studied signals related to specific T-cell receptors and more general resources like cytokine signals or space availability. They assessed T cell receptor diversity to determine overall T cell levels and to count T cells of certain kinds. ...

Early treatment of systemic onset JIA with anakinra restores the IL-18 response

...as shown that, once NK cell levels and function are restored to normal, the cytokine pathway specifically involving IL-18 is restored, which elicited a good cli...During a six month follow-up period, absolute NK cell numbers and function, cytokine profiles, and NK cell response after IL-18 stimulation, were monitored. F...

Novel DNA vaccine leads to kidney damage prevention in systemic lupus erythematosus models

... Copenhagen, Denmark, Thursday 11 June 2009: DNA vaccination using lupus autoantigens and interleukin-10 (IL-10, a cytokine that plays an important role in regulating the immune system) has potential as a novel therapy to induce antigen specific tolerance and may help to pr...

Genetic pathway responsible for link between body clock disturbance and worsening arthritis

...ry gene CRY was found to up-regulate expression of a gene which promotes the activation of TNF-alpha (tumour necrosis factor-alpha, a pro-inflammatory cytokine used by the body to boost the immune system) by two fold, when comparing mice with the CRY gene removed to those with a normal copy of the gene. Pro...

Immunologists identify biochemical signals that help immune cells remember how to fight infection

...n another type of immune cell called CD8+ T lymphocytes. For these cells, whether they become killers or long-term memory cells depends upon which cytokine they respond to. Those that receive the IL-12 become killers while those that receive interferon alpha turn into long-term memory cells. "Regardles...

CEL-SCI Corporation Reports 2009 Second Fiscal Quarter Financial Results

...ne may be able to work around that problem. While normally cytokines may play a key role in preventing and treating swine flu, in some cases excessive cytokine amounts may exacerbate disease as it appears that, unlike the normal flu which affects the very young and very old most severely, swine flu may be mor...
Cytokine in Medical Technology

Cytokine PharmaSciences Initiates Phase I Study of Oral Anti-Inflammatory Agent, CPSI-2364

... KING OF PRUSSIA, Pa., July 20 /PRNewswire/ -- cytokine PharmaSciences, Inc. today announced the initiatio...nic," said Dennis F. Willson, president and CEO of cytokine PharmaSciences. "As a small molecule, CPSI-2364 i...ed the oral activity of CPSI-2364. About cytokine PharmaSciences ...

USC Keck School of Medicine's Dr. Alan Epstein Receives Prestigious National Cancer Institute RAID Award for Breakthrough IL-2 Molecule Therapeutic

...te (NCI) for his breakthrough Interleukin-2 (IL-2) cytokine immunotherapy analog. This is the second RAID aw...that currently limit their application. IL-2 cytokine immunotherapy is used to treat metastatic melanoma...ect of capillary leak syndrome while retaining the cytokine and therapeutic activity of IL-2. His extensive p...

Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome

...and will be published in the upcoming July 2009 print edition in an article titled: A Selective Inhibitor of the Immunoproteasome Subunit LMP7 Blocks cytokine Production and Attenuates Progression of Experimental Arthritis . The authors of the article included members of the laboratory of Dr. Marcus Groettr...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

...rious control groups did not. Gamma interferon, a cytokine that helps regulate the body's immune response, is...ious diseases such as pandemic flu and cancer. The cytokine IL-12 is the first step in gamma interferon produc...ble results in humans. The lack of proinflammatory cytokine production in responses to the L.E.A.P.S. vaccines...

Agennix Receives Fast Track Designation From FDA for Talactoferrin in Combination With Sunitinib for Renal Cell Carcinoma

... surgical removal of the kidney (nephrectomy), followed by observation. If the cancer spreads beyond the kidneys, treatment may include chemotherapy, cytokine therapy, targeted therapy, and/or radiation. Currently, sunitinib is the most prescribed targeted therapy for first-line treatment of RCC. Abou...

Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)

...hophysiological effects of TNF-alpha. Over the past decade, TNF-alpha has emerged as a major target of basic research and clinical investigation. This cytokine plays a key role in mediating pathological inflammation, and excess TNF-alpha production has been directly implicated in a wide variety of diseases. T...

Studies Presented at AACR Annual Meeting Highlight Multiple Immunomodulatory Mechanisms of Peregrine's PS-Targeting Antibodies

...s PS-Targeting Antibodies Stimulate Dendritic Cell Maturation, Inflammatory cytokine and Chemokine Release and Recruitment of Macrophages to Tumors - DENVE...ng evidence suggesting that PS-targeting antibodies facilitate an important cytokine shift in the tumor environment that subsequently encourages multiple types ...

Novel Valortim(R) Mechanism of Action Data Presented at the Keystone Symposia on Molecular and Cellular Biology

...s on human dendritic cells (CD40 and CD83), and (3) allows for an augmented cytokine response, particularly the pro-inflammatory cytokine IL-23 that is known to stimulate memory T cells and the production of IFN-g...

XTL Biopharmaceuticals Announces the Acquisition of the Use Patent on Recombinant Erythropoietin (rHuEPO) for the Treatment of Multiple Myeloma

...ing is expected to take place in the second or third quarter of 2009. ABOUT ERYTHROPOIETIN (EPO) Erythropoietin (EPO) is a glycoprotein cytokine produced mainly by the kidney and is the major growth regulator of the erythroid lineage. EPO stimulates erythropoiesis by binding to its receptor (EP...

IBT Laboratories to Launch New Pneumococcal Antibody Avidity Test at AAAAI Meeting, Booth 729

...IBT will present two scientific posters at the conference: Saturday, 9:45-10:45 am - # 41: T Cell Immunity Assessed by Intracellular cytokine Analysis Following Stimulation of Whole Blood or PBMCs with Microbial Antigens of Mitogens Sunday, 9:45-10:45 am - # 405: Presence of IgG An...
Cytokine in Biological News

Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection

Attaching a recently discovered cytokine to neural stem cells derived from bone marrow, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute have developed a tool to track and kill malignant brain tumor cells and provide long-term protection against their return. Res...

Discovery to aid in future treatments of third-world parasites

...immune cells. Due to their fundamental importance, cytokine research is a significant focus of research at the... their role. Trudeau investigators have devised cytokine "reporter mice" for tracking cells that produce the signature cytokine of the so-called "Th2" immune response mounted aga...

Peregrine's PS-targeting antibodies highlighted in AACR Annual Meeting studies

...or components of the immune system. Together, the studies provide compelling evidence suggesting that PS-targeting antibodies facilitate an important cytokine shift in the tumor environment that subsequently encourages multiple types of immune system cells to mount anti-tumor responses." In a presentatio...

'First aid' for brain cells comes from blood

...wn that certain immune cells in the blood inhibit inflammation after a stroke. These cells are known as regulatory T lymphocytes (Treg). The regulator cytokine Interleukin 10 plays an important role in this protection, perhaps offering a new approach to stroke therapy. The study has now been published in Na...

Time (and PPAR-beta/delta) heals all wounds

...e in OTCs by secreting extra doses of several growth factors. The fibroblasts were stimulated to produce these growth factors by keratinocyte-released cytokine IL-1 - underscoring the reciprocity between the two cell types. Blocking either the IL-1 signal or any of the growth factors released by the fibroblas...

Tobacco makes medicine

...ich would work most effectively. The researchers found that tobacco plants were able to process both forms of IL-10 correctly, producing the active cytokine at high enough levels that it might be possible to use tobacco leaves without lengthy extraction and purification processes. The next step will be to ...

Shades of 1918? New study compares avian flu with a notorious killer from the past

...ough the 1918 ressortant strains were found to be highly virulent, they were outmatched by H5N1's rapid onset, overwhelming transcription induction of cytokine and chemokine genes and headlong, sustained viral replication with wider distribution in the lungs. As Baskin notes, referring to the group's measurem...

The quest for specific anti-inflammatory treatment

...es cell inflammation, i.e. when the cells detect the presence of this molecule, they secrete molecules that generate inflammation - prostaglandin and cytokine cells, for example. But this process does not occur with all types of cells. Although apparently contradictory, in some cells this same molecule fu...

Apolipoprotein(a): A natural regulator of inflammation

...ssor of the inflammatory response in vivo. In addition, a mechanism for this novel function of apo(a) was also identified: its selective regulation of cytokine production. These effects of apo(a) are independent of its molecular mimicry of Plg. Lipoprotein(a) (Lp(a)) is similar to low density lipoprotein (...

Forsyth scientist receives major grant to support rapid, accurate, affordable test for tuberculosis

... Dr. Antonio Campos-Neto, head of the department of cytokine Biology at The Forsyth Institute, has received a major grant from the internationally renowned Foundation for Innovative New Diagnostics (FIND) to con...
Cytokine in Biological Technology

GeneGo Donates Proprietary Cytokine Pathway Maps to ISICR

ST. JOSEPH, Mich.,. July 21 /PRNewswire/ -- GeneGo, Inc., the leading systems biology tools company, announced today that they have recently donated 41 canonical pathway maps to the International Society for Interferon and Cytokine Research (www.isicr.org). These maps are constructed fro...

Selection of Standards for Bio-Plex Cytokine Assays, Rev A

Diana Davis, Aiguo Zhang, Jim Torrence, and Emily Dale, Bio-Rad Laboratories, Inc., 2000 Alfred Nobel Drive, Hercules, CA 94547 USA Introduction Bio-Plex cytokine assays are bead-based quantitative multiplex immunoassays. The concentr...

Correlation of Bio-Plex Suspension Array Reader Validation With Multiplex Cytokine Assay Performance, Rev A

Chloe Etienne, Allan Gandy, Diana Davis, and Aiguo Zhang, Bio-Rad Laboratories, Inc., 2000 Alfred Nobel Drive, Hercules, CA 94547 USA Introduction The Bio-Plex suspension array system is an integrated system consisting of hardware, so...

Bio-Plex Cytokine Immunoassays and ELISA: Comparison of Two Methodologies in Testing Samples From Asthmatic and Healthy Children, Rev A

Maria C Jenmalm, 1 Michele Malit, 2 Jim Torrence, 2 and Aiguo Zhang, 2 1 Department of Molecular and Clinical Medicine, Division of Paediatrics, Linkping University, Sweden, and 2 Bio-Rad Laboratories, Inc., 2000 Alfred Nobel Drive,...

LiquiChip Kits for bead-based cytokine and kinase assays

The LiquiChip Human and Mouse 10-Cytokine Kits and Ser/Thr Kinase Kit provide fast and accurate quantification of a range of cytokines and serine/threonine kinases. LiquiChip 10-Cytokine Kits enable simultaneous multiplex assay o...

2009: Immunotec announces important clinical research initiative: New study to be launched with the goal of improving the quality of the aging process

... Cysteine-Rich Whey Protein Isolate (Immunocal(R)) in Combination with Physical Exercise on Muscle Function, Body Composition and Inflammatory cytokine Levels in Elderly Persons: A Randomized, Double-Blind Study. MONTREAL, July 7 /PRNewswire-FirstCall/ - Immunotec Inc. (TSX-V: IMM) announced...

Scripps Research Institute Highlights Groundbreaking Work of aTyr Pharma Scientific Co-Founder

...in drugs. According to Jeff Watkins, CEO of aTyr Pharma, "By separating specific residues in the human tyrosyl tRNA synthetase required for novel cytokine activities from those involved in the protein synthesis activities, Professor Yang has proven that these naturally occurring activities hidden in the ...

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

...hophysiological effects of TNF-alpha. Over the past decade, TNF-alpha has emerged as a major target of basic research and clinical investigation. This cytokine plays a key role in mediating pathological inflammation, and excess TNF-alpha production has been directly implicated in a wide variety of diseases. T...

CEL-SCI Developing Immune-Based Treatment Against Swine and Other H1N1 Flu Viruses Using Proprietary L.E.A.P.S. Technology

...onse was too strong (too many pro-inflammatory cytokines). This is called a cytokine storm. While normally many cytokines play a key role in preventing and treating swine flu, in some cases excessive cytokine amounts may exacerbate the disease as it appears that, unlike the normal fl...

CEL-SCI's L.E.A.P.S. Technology Shows Potential to Treat Swine Influenza in Preclinical Studies

...ay a key role in preventing and treating swine flu, in some cases excessive cytokine amounts may exacerbate disease as it appears that, unlike the normal flu wh...cine's antigen(s) to the appropriate T lymphocyte and then deliver specific cytokine proteins to the T cell to determine the immune response outcome to the spec...
Cytokine in Biological Products

ChemiArray Mouse Lysate Cytokine Antibody Array III, 62 cytokines per membrane from CHEMICON

Description: Request Info...
Company:CHEMICON

Custom Human Cytokine Antibody Array, Choose from hundreds of proteins. from Raybiotech, Inc.

Description: ...
Company:Raybiotech, Inc.

Human Cytokine Antibody Array 1.1 (4) Kit, RayBio from Raybiotech, Inc.

Description: RayBio Human Cytokine Antibody Array 1.1 (4 array membranes) with Accessory, detects 20 cytokines (for lysate) Class: Antibody Array Products Product Group: Antibody Array...
Company:Raybiotech, Inc.

Cartesian Array Human Cytokine Set 1 from BioSource International (Invitrogen)

Description: ...
Company:

Mouse Hematopoietic Stem Cell Expansion Cytokine Panel from R&D Systems

Description: Hematopoietic stem cells (HSC) are well-characterized tissue-specific stem cells that exhibit remarkable self-renewal capacity and are responsible for the life-long maintenance of the hematopoietic system. HSC are rare cells that reside in adult bone marrow where hematopoiesis is continuously takin...
Company:R&D Systems

RayBio Human Cytokine Antibody Array I &1.1 Service from Raybiotech, Inc.

Description: Request Info...
Company:Raybiotech, Inc.

Custom Human Cytokine Antibody Array, Choose from hundreds of proteins. from Raybiotech, Inc.

Description: Request Info...
Company:Raybiotech, Inc.

Q-Plex Rat Cytokine Array (Stripwells) from BioLegend

Description: Distributed exclusively by BioLegend, the Quansys Biosciences Q-Plex Array is a new technology for multiplex analysis of cytokines/chemokines for human, mouse, and rat research. The Q-Plex Rat Cytokine Array is a fully quantitative ELISA-based test where 4 distinct capture antibodies have been abso...
Company:BioLegend

Mouse IR Cytokine Array 12plex from Pierce Biotechnology, Inc.

Description: The SearchLight® IR Mouse Cytokine Array is a multiplex sandwich ELISA (enzyme-linked immunosorbent assay) for the quantitative measurement of 12 cytokines in serum; EDTA, heparin, sodium citrate plasma and culture supernatants. Each well of the microplate provided is spotted with antibodies t...
Company:Pierce Biotechnology, Inc.

Human Atherosclerosis Antibody Array I Kit, ChemiArray, 20 cytokines per membrane from CHEMICON

Description:... ChemiArray Human cytokine Antibody Array VII, 60 cytokines per membrane...
Company:CHEMICON

More>>

Cytokine in Biological Definition

Apoptosis

... inhibiting factors are present at each step of these pathways. Tumor necrosis factor ( TNF ), a 157 amino acid inter-cellular signaling molecule ( cytokine ) produced mainly by activated macrophages, and is the major extrinsic mediator of apoptosis. The cell membrane has two specialized receptors for TNF:...

Monoclonal antibody

...ntigen and induce an immunological response on the target cancer cell. Such mAb could also be modificated for delivery of a toxin , radioisotope , cytokine or other active conjugate; it is also possible to design bispecific antibodies that can bind with their Fab regions both to target antigen and to a ...
Cytokine in Biological Dictionary

Transmembrane receptor

...Transmembrane Receptors and Channels Volume 6 Biomembranes A Multi Volume Treatise 2nd edition by from... ... Regulated Transmembrane Enzymes. cytokine Receptors . Ligand-Gated ... Drug (ligand)-regulated transmembrane enzymes (may involve receptor tyrosine kinases) ... The Worldwide Intensi...

MicroRNA

...s: gene expression, microRNA , molecular biology ... MicroRNA and cancer. Human gene count drops again ... MicroRNA . Diophantine equations. cytokine storms ... Pair Of MicroRNA Molecules Controls Major Oncogene In Most Common Leukemia (12 ... Labels: cancer, let-7, microRNA , Myc, news dump, ...

Granulocyte

...fer from ... Granulocyte colony-stimulating factor (G-CSF or GCSF) is a colony-stimulating factor hormone. It is a glycoprotein, growth factor or cytokine produced by a number of different tissues to stimulate the bone marrow to produce... Definition of granulocyte from the Merriam-Webster Online Di...

Effector cell

... stimulation down-regulates CCR7 on effector T cells . ... Moreover, P14.CCR7 effector cells localized almost exclusively in the splenic ... cytokine control of effector ... The role of other... Regulating CD8 T cell ... generate large numbers of effector T cells while simultaneously minimizin...

CDNA array

...ouse 1.2 ... TWC BioSearch is your ONE-SOURCE agent for the supply of Molecular Biology, Immunology and Cell Biology in China, Singapore ... cDNA cytokine Expression Array ... We selected cDNA clones for array construction using the TIGR HGI as part of a ... The cDNA clones in this array ...
Other Tags
(Date:8/23/2014)... August 23, 2014 Having been in the ... hygienist from Arlington, Texas, saw a need for an effective ... "That’s when I came up with the idea for my ... an effective way for a user to clean the mouth ... carry multiple items. It also helps avoid plaque buildup and ...
(Date:8/23/2014)... Legal Insider Bot - a ... has been generating a buzz of media excitement following ... the new product has drawn the attention of HonestyFirstReviews.com’s ... “In recent years the market has been flooded with ... as robots or ‘bots,'” reports Hendricks. “As a ...
(Date:8/23/2014)... MA (PRWEB) August 23, 2014 Professional ... have a study aid in preparing for Food Safety ... practice test by Dynamic Path. , Dynamic Path ... module, which includes more than 200 review questions for ... materials are designed to cover requirements of the ServSafe® ...
(Date:8/23/2014)... Youth substance abuse is a serious ... in Houston, TX. Substance abuse can happen to people ... and alcohol dependency in higher numbers than ever before. ... abuse, but don’t know where to find professional youth ... a challenge because most treatment options are designed for ...
(Date:8/22/2014)... 23, 2014 Search Engine Optimization ... first page of search engines and get more ... has recently compared many Linux hosting suppliers and ... are the most recommended Linux hosting suppliers for ... Europe to buy high quality Linux hosting (including ...
Breaking Medicine News(10 mins):Health News:Legal Insider Bot Review Examining Greg Marks’ Trading Software Released 2Health News:Food Handler Safety Certification Made Easy with Dynamic Path 2Health News:New Houston Hotline Assisting Juveniles in Locating Dependable Rehabilitation Help 2Health News:Top10BestSEOHosting.com Announces Best Cheap Hosting Suppliers Of This Summer 2
(Date:8/22/2014)... German . ... are fixated in a way so as to align ... and Fudan University researchers are planning on looking into ... findings are being published today in the scientific journal ... sensitive molecules. Everyone knows that at least from ...
(Date:8/22/2014)... strong antioxidants and can reduce free radical ... against oxidative stress? Jianbo Zhao and co-workers ... Medical University, China discovered that green tea ... neuronal apoptosis, indicating green tea polyphenols play ... under oxidative stress. The relevant study has ...
(Date:8/22/2014)... In 2015, American consumers will finally be able to ... Although touted as zero-emissions vehicles, most of the cars ... fossil fuel that contributes to global warming. , Now ... device that uses an ordinary AAA battery to produce ... electric current through two electrodes that split liquid water ...
Breaking Biology News(10 mins):Proteins: New class of materials discovered 2Stanford scientists develop a water splitter that runs on an ordinary AAA battery 2Stanford scientists develop a water splitter that runs on an ordinary AAA battery 3
Other Contents