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Cystine in Medical News

2009 Science Report on Genetic Disease Released by Cystinosis Research Foundation

...n 25 years," she said. In patients with cystinosis, the amino acid cystine accumulates in the tissue due to the inability of the body to transport cystine out of the cell. This causes development of crystals, resulting in early ce...

AUA 2008: Uric acid stones may indicate arteriosclerotic diseases

...cause low urine pH, and researchers hypothesize that these patients would be more likely to develop uric acid stones (rather than calcium, struvite or cystine stones). By retrospectively reviewing the charts of 467 patients whose renal and ureteral stones were analyzed, researchers discovered a strong associ...

Virus Causing Kaposi's Sarcoma Discovered

...epartment of Health and Human Services. Reference: JAR Kaleeba and EA Berger. Kaposi's sarcoma-associated herpesvirus fusion-entry receptor: cystine transporter xCT. Science DOI: 10.1126/science.1120878 (2006) ...
Cystine in Medical Dictionary

Cystinuria

...disorder that is characterized by the formation of cystine stones in the kidneys, ureter, and bladder. C...ry ... Learn about Cystinuria - an excess of cystine / cystine stones in the urine. ... What are the signs and sy...
Cystine in Biological Technology

Raptor Pharmaceuticals Corp. Announces Presentation at 5th International Cystinosis Conference 2008

...cterized by abnormal transport of cystine, an amino acid, out of the lysosomes. Symptom onset typically occurs within the first year after birth, when cystine crystals accumulate in various tissues and organs, including the kidneys, brain, liver, thyroid, pancreas, muscles and eyes. Failure to treat the dise...

Raptor Pharmaceuticals Corp. Enters Agreements to Advance Clinical Pipeline

...ed by the FDA for the management of nephropathic cystinosis ("cystinosis"), a genetic lysosomal storage disease characterized by the poor transport of cystine out of lysosomes. Ted Daley, President of Bennu stated, "We are delighted to extend our relationship with UCSD. Additional rights to Cysteamine in N...

Raptor Pharmaceuticals Acquires Orphan Clinical Program

...is a proprietary enterically coated formulation of cysteamine bitartrate, a cystine depleting agent currently approved by the U.S. Food and Drug Administration...nosis"), a lysosomal storage disease characterized by the poor transport of cystine out of lysosomes. If left untreated, this disorder is associated with a hig...

Efficient Primary Structure Elucidation of Disulfide-bridged Peptides

...ily of ion channel toxins containing the inhibitor cystine knot structural motif. The proximity of the cystei... thewell-known consensus sequence of the inhibitor cystine knot structural motif: CX3-7CX3-10CX0-7CX1-8CX4-20...comparison with other spider toxins containing the cystine knot structure. Cell Mol. Life Sci., 2001, 58, 153...
Cystine in Biological Definition

Amino acid

... 121.16 5.05 1.92 10.70 8.37 Under oxidizing conditions, two cysteines can join together by a disulfide bond to form the amino acid cystine . When cysteines are part of a protein, insulin for example, this enforces tertiary structure. D Asp Aspartic acid acidic 133.1...

Disulfide bond

...ms S-S bonds in proteins in cysteine . When two cysteines are bonded by an S-S bond, the resulting molecule between the two protein chains is called cystine . The figure below shows the formation of a disulfide bond. The R on each side group represents the remainder of the amino acid. R ...
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