Biogen Idec's baminercept alfa shows promise in patients with rheumatoid arthritis
"Long-term safety assessment of Baminercept alfa (BG9924, LTR-Ig) in cynomolgus
monkeys (Poster FRI0156 Friday, June 13, 11:45 13:30 CEST)
"Treatment of cynomolgus
monkeys with Baminercept alfa (BG9924, LTR-Ig) results in modulation of a s...
Subordinate monkeys more likely to choose cocaine over food
...San Diego. The presentation was part of the scientific program of the American Society for Pharmacology and Experimental Therapeutics (ASPET).
monkeys live in a complex social structure in which the social hierarchy is established by physical aggression and maintained by clear signals. A monk...
Animal Study Links Social Standing With Drug Use Risk
... stressful situation, a new study finds.
The Wake Forest University School of Medicine researchers exposed four dominant and four subordinate male cynomolgus
monkeys to a socially stressful situation. Each monkey was taken out of its home cage and placed in an unfamiliar cage surrounded by four unfamiliar a...
Cynomolgus in Medical Technology
Cynomolgus in Medical Dictionary
...bola virus is transmitted by direct contact with the blood, secretions, ... The transmission of the Ebola Reston strain through the handling of cynomolgus
... Ebola -Côte d'Ivoire. 1. 0. 0% 1995. Democratic Republic of Congo (formerly ... 1A fourth virus subtype, Ebola -Reston, was detected in Oc...
Cynomolgus in Biological News
Birth control has long-term effect on hormone exposure
...effect of post-menopausal dietary soy consumption on estrogen metabolism in cynomolgus
monkeys, Latanya M. Scott, Ph.D., discovered that monkeys who had been give...the National Institutes of Health, researchers began with 181 premenopausal cynomolgus
monkeys and followed them for seven years in a study designed to look at ho...
Environmental enrichment can reduce cocaine use, researchers find
...f cocaine that monkeys will self-administer. Housed in groups of four, male cynomolgus
monkeys will invariably stratify by social rank from the most dominant to t... Therapeutics (ASPET).
Nader and colleagues worked with a group of 24 cynomolgus
macaques who were already categorized socially. For additional enrichment, ...
Cynomolgus in Biological Technology
Celsis Outlines the Top Five Advantages of Cryo-plateable Hepatocytes
A High Throughput Screening Assay for Hepatotoxicity Using Cryopreserved Hepatocytes
Comparison of Fresh and Cryo cynomolgus
Monkey Hepatocyte CYP P450 Levels
1 Drug Interaction Studies - Study Design, Data Analysis, and Implications for Dosing and Labe...
AACR 100th Annual Meeting Highlights Superior Ability of InNexus' DXL-Modified Anti-CD20 Antibody to Attach and Kill NHL With Safety Comparable to Approved Antibody Therapies in Preclinical Studies
InNexus' AACR presentations are titled, " A Novel High Avidity Anti-CD20 With Markedly Increased Cytotoxicity Shows No Systemic Toxicity In The cynomolgus
Monkey At A Dose 100-Fold Above The Anticipated Therapeutic Dose ", (AACR# 1231) and " Oxidative Modification Of An Anti-CD20 Antibody Imparts Autophi...
PharmAthene Presents Data for SparVax(TM) and Valortim(R), a Novel Vaccine and Anti-Toxin for the Prevention and Treatment of Anthrax Infection at the 7th Annual ASM Biodefense Meeting
...tional anthrax in certain primates such as African Green Monkeys (AGMs) and cynomolgus
monkeys (cynos) is believed to follow a similar disease course as in humans...models. Additional PK testing of Valortim(R) is currently ongoing.
PK project was funded in whole or in part with Federal funds from the Natio...
InNexus Biotechnology Announces Launch of Large Scale Primate Study of DXL625
...hnology, announced today that it has launched a large scale
primate study of DXL625 (CD20), the company's lead program.
"We are beginning a study in cynomolgus
monkeys of DXL625, an antibody
directed against the B-cell marker CD20 and enhanced in potency with our
DXL(TM) technology," said Thomas Kindt, Ph.D.,...
Analysis of a Verapamil Microsomal Incubation using Metabolite ID and Mass FrontierTM
...re used in order to generate the maximum number of metabolites. The UDPGA was added to generate phase two glucuronide conjugates. Microsomes from male cynomolgus
monkeys, male Wistar rats, and male Beagle dogs were used to probe interspecies variations in metabolism. The incubation mixtures were analyzed withou...
Cynomolgus in Biological Products
Cynomolgus in Biological Dictionary
... sheds a residual body containing membrane ... A round spermatid was drawn into the injection pipette (Figure 2 b-1) ... Pronucleus formation in cynomolgus
monkey oocytes post-round spermatid injection (ROSI) ... Since fertilization by round spermatid nucleus was first reported (Ogura and ......