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Cyclic in Medical News

Drug Might Restore Sense of Smell

...s had previously discovered that people with hyposmia had reduced levels of cyclic nucleotides in their saliva and nasal mucous, and that treatment with theop...els of this growth factor and restored some of the sense of smell. These cyclic nucleotides are growth factors for olfactory (related to smell) and other n...

Another Genetic Link to Testicular Cancer Is Found

...Health and Human Development, said in the news release. The PDE11A gene is located in a key biochemical pathway in testicular germ-cell cancer, the cyclic AMP pathway, which regulates how cells respond to such signals as hormones. Drugs that affect the AMP pathway are widely available and, in theory, may...

Materials and Processes for Medical Devices Event Brings Clinicians, Engineers, Designers Together

...and regulators of both vascular and orthopedic implants. The effects of various manufacturing procedures, surface conditions and surface damage on the cyclic polarization, ion-leaching, and fatigue performance of implant materials will be examined. Effect of Materials on Surgical Techniques will address...

Second gene linked to familial testicular cancer

...cancer." The key pathway in this disease is the cyclic AMP pathway, which regulates how cells respond to such signals as hormones. Drugs that affect the cyclic AMP pathway are widely available, and, in theory, ...nzyme that slowed down the enzyme's destruction of cyclic AMP. "The mutations don't cause cancer directly...

Meckel's diverticulum masked by intermittent recurrent subocclusive episodes

... but painless hemorrhage, the classical presenting symptom of Meckel's diverticulum, was never experienced. These symptoms were firstly interpreted as cyclic vomiting of childhood. Only the persistence of the condition accompanied by weight loss prompted physicians to investigate further. A supravesical mas...

BioFit Intensive Plus™ Chairs Meet Federal Standard for Continuous Intensive Use

...Use Chairs. The protocol included a series of four cyclic durability and load tests of the backrest, seat an...mpliance in two back durability and tilt mechanism cyclic tests was granted only if the chair and all pertin...he case of the fourth portion of the protocol, the cyclic Increasing Back Load Test, the acceptance level wa...
Cyclic in Medical Technology

Ironwood and Collaborators Present Preclinical Data Demonstrating That Cyclic GMP Alleviates Intestinal Pain

- Data Presented at ACG Annual Scientific Conference - ORLANDO, Fla., Oct. 6 /PRNewswire/ -- Ironwood Pharmaceuticals (formerly Microbia) today announced presentation of data from a pair of preclinical studies delineating the role that cyclic guanosine monophosphate (cGMP) plays in al...

BIOCOM's 4th Annual DeviceFest Honors Companies

...revent accidental needlestick injuries. "The Far Out" award went to CVAC Systems, Inc for its unique capsule device focused on the application of its cyclic Variations in Altitude Conditioning process to treat diseases and disorders associated with aging, including insulin resistance, diabetes, neuropathy,...

Michael J. Fox Foundation Awards $2.7 Million to Four Industry Teams for Pre-Clinical Parkinson's Disease Research

...g of Disease Progression and Therapeutics Interventions in Parkinson's Disease Patrizia Fanara, Ph.D., KineMed, Inc. Selective Inhibition of cyclic Nucleotide Phosphodiesterase Type 7 (PDE7): A Novel and Efficacious Approach to Treating Parkinson's Disease Vincent Allen Florio, Ph.D., Omeros Co...

University of Miami Team Confirms Value of Monitoring Cell-Mediated Immunity Pre- and Post-Transplant in Management of Kidney Transplant Recipients

...transplant recipients," will be presented on June 2 at the annual meeting of the American Transplant Congress in Toronto, Canada. "The production of cyclic adenosine monophosphate (cAMP) by mitogen-stimulated peripheral CD4+ T-cells using the ImmuKnow assay has previously be shown to have utility in the m...

Increases in West Nile Virus Replikin Concentrations Precede Increases in the Number of Human Cases

...eptides, specified in virus genomes, which increase in concentration signaling rapid replication before virus outbreaks. This is the first report that cyclic increases in virus replikin concentration, each apparently building on the last, can be a mechanism of virus expansion into a territory. In the pres...

Genaera Corporation Announces MSI-1436 Data Presented at Society of Neuroscience Meeting

... a definitive study to resolve this discrepancy was designed. The effects of MSI-1436 on dopamine reuptake were investigated using in vivo fast-scan cyclic voltammetry in anesthetized rats. A stimulation train was delivered to the ventral tegmental area every five minutes and the resultant dopamine and ra...
Cyclic in Medical Dictionary

Vomiting

...ear-old has not been himself all day. ... This isn't really considered a vomiting problem but rather a coughing ... Describes the four phases of cyclic vomiting syndrome and the current treatment options available. Outlines the complications associated with the disorder and ... The common ca...

Ultrasound

... Ultrasound is cyclic sound pressure with a frequency greater than the upper limit of human hearing. Although this limit varies from person to person, it is approximately 2...

Premenstrual syndrome

...s signs and symptoms, treatments and self-care remedies. ... been learned about premenstrual syndrome . ... Premenstrual syndrome , a common cyclic disorder of young and middle-aged women, ... Is evening primrose oil of value in the treatment of premenstrual syndrome ? ... Premenstrual ...

Neutropenia

... Neutropenia Support Association's webpage to get more information ... Important It is possible that the main title of the report Neutropenia , cyclic is not the name you expected. Please check the synonyms listing to find the alternate ... Important It is possible that the main title of the repo...

Menstruation

...on (the menses), as in ... Menstruation , commonly called a woman's period, is the approximately monthly ... Menstruation is a normal, natural cyclic process occurring in all healthy adult ... Physician developed information about menstruation , including info about the menstrual cycle. ... htt...

Ketones

... ketones . What additional monitoring does the doctor do? ... Aldehydes and ketones are organic compounds which incorporate a carbonyl ... In cyclic ketones the carbonyl group is assigned position #1, and this number is ... Diabetic ketoacidosis (DKA) is a state of inadequate insulin levels...
Cyclic in Biological News

August 2009 Geology and GSA Today media highlights

...ns present paradoxical results. While ice volumes of similar size to those implied by proxy evidence are simulated, sea-level changes brought about by cyclic variations in Earth's orbit are minuscule. It is only with large perturbations to atmospheric greenhouse gas concentrations that observed sea-level ch...

MicroRNAs grease the cell's circadian clockwork

...s an internal clock, a group of genes displaying a cyclic expression pattern that reaches a peak once a day....sidiary oscillators, a group of genes displaying a cyclic expression pattern that reaches a peak every twent...erol and lipids, are expressed in liver cells in a cyclic fashion. Many of them are also influenced by rhyth...

Scientists find formula to uncover our planet's past and help predict its future

...California and Lancaster were able to successfully recreate measurements in a study on a vole-mustelid community. Many small mammalian species have cyclic population dynamics, periodically oscillating between large and small communities, a behavioral phenomenon which has puzzled ecologists for decades. R...

New findings in taste and smell

...sory adaptation in the vomeronasal organ Emx2 stimulates odorant receptor gene expression and controls OSN axon growth Hyperpolarization-activated cyclic nucleotide-gated channels in olfactory sensory neurons mediate axon targeting and glomerular formation Investigations of olfactory receptor internal...

The law of the weakest

...test would survive. LMU researchers have now simulated the progression of a cyclic competition of three species. It means that each participant is superior to...esearching conditions and mechanisms that affect the biodiversity of Earth. cyclic dominance is a particularly interesting constellation of species competing ...

Long-sought protein structure may help reveal how 'gene switch' works

...this week, the NIST/BNL team reports that it has definedfor the first timethe structure of a "metabolic switch" found inside most types of bacteriathe cyclic AMP (cAMP) receptor protein, or CRPin its "off" state. CRP is the "binding site" (attachment point) for cAMP, a small molecule that, once attached, se...
Cyclic in Biological Technology

cAMP DataFile: Homogenous Cyclic AMP detection using High Efficiency Fluorescence Polarization

A Sensitive, Robust, Homogenous, and Rapid Assay Uses High Efficiency Fluorescence Polarization (HEFP) detection method Detects pmol amounts of cAMP Optimized for cell extract and enzyme preparations Requires no separation or wash steps Available in a kit and in bu...

Development of a sensitive enzyme fragment complementation assay for cyclic adenosine 3', 5' monophosphate and its validation for pharmacological screening at G protein-coupled receptors

Key words: cAMP • GPCR • enzyme fragment complementation • LEADseeker • assay miniaturization G protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors and are responsible for the transduction of ...

Performance of Ad-A-Gene Cyclic AMP Response Element-Nitroreductase (CRE-NTR): an adenoviral vector gene delivery system

Key words: adenoviral vector ● viral transduction ● NTR ● IN Cell Analyzer ● gene delivery Biological assays developed in cultured and primary cells can greatly aid secondary screening as well as lead and target validation, but ...

Palatin Technologies, Inc. Receives U.S. Patent Allowance for Heart Failure Drug Candidate

... "Cyclic Natriuretic Peptide Constructs." Allowed claims cover a family of cyclic compounds that bind to natriuretic peptide receptor A (NPRA), including PL-...y of once-daily administration." PL-3994 and the related family of cyclic compounds were discovered entirely in-house and are owned by Palatin. In a...

New drugs faster from natural compounds: A UC San Diego breakthrough

...UC San Diego. "Compound 879," for example, is a cyclic NRP discussed in the Nature Methods paper that w...nerated from the mass spectrometers that break the cyclic peptides into smaller and smaller linear pieces. ... in order to determine the chemical structure of a cyclic NRP. This is called "De Novo sequencing of NRPs." ...

New method may accelerate drug discovery for difficult diseases like Parkinson's

...this approach are extremely small proteins, called cyclic peptides, which are capable of targeting the prote...tions among proteins that occur at these surfaces. cyclic peptides have the ability to bind where traditiona...te University, Kritzer created a vast "library" of cyclic peptides containing various amino acid combination...
Cyclic in Biological Products

cAMP ELISA Kit, Colorimetric competitive from R&D Systems

Description:... For the quantitative determination of cyclic AMP (cAMP) concentrations in cell culture supernates, serum, plasma, saliva, urine and cell lysates....
Company:R&D Systems

Mechanical Cell Strain Instrument STREX ST-140-04 from B-Bridge International

Description:...ain chambers with precise uniaxial mechanical strain. The robust and easy to use design ensures that cells grow over long periods of time with regular cyclic stretching or compression. This unit allows you to control the frequency and degree of the strain to produce 64 unique strain settings. The instrument...
Company:B-Bridge International

Phosphodiesterase I from USB Corp.

Description:... at 25C, pH 8.9. Concentration: greater than or equal to 20 units/mg Applications: *Base composition and nearest neighbor analysis (1) . *Removal of cyclic AMP from protein preparations. References: *HO, N. W. AND GILHAM, P. T. (1973) Biochem. Biophys. Acta, 308, 53-58. *LASKOWSKI, M. (1971) in The Enz...
Company:USB Corp.

RNase ONE™ Ribonuclease from Promega

Description:... RNase ONE Ribonuclease is a 27kDa periplasmic enzyme from E. coli that catalyzes the degradation of RNA to cyclic nucleotide monophosphate (NMP) intermediates. Slower hydrolysis further catalyzes the degradation of these intermediates to 3-NMPs (1). RNase ONE Ribo...
Company:Promega

Pyrophosphate Fluorometric (Blue) Assay Kit, EnzChek® from Molecular Probes (Invitrogen)

Description:...hotometric method for measuring the inorganic pyrophosphate (PPi ) produced by a number of biochemical reactions, such as DNA and RNA polymerizations, cyclic AMP formation by the enzyme adenylate cyclase and the enzymatic activation of fatty acids to form their coenzyme A esters.1 The EnzChek Pyrophosphate ...
Company:Molecular Probes (Invitrogen)

Canine Endostatin EIA Kit from Neogen Corporation

Description:...le assays. The quantitative test kits detect hormones, steroids, prostaglandins, leukotrienes, cytokines, growth and angiogenic factors, thromboxanes, cyclic nucleotides and lipoxins in a wide range of sample and specie types. These test kits are used worldwide by research laboratories, pharmaceutical resea...
Company:Neogen Corporation
Cyclic in Biological Definition

Adenosine triphosphate

...denosine diphosphate (ADP) Adenosine monophosphate (AMP) ATPases ATP hydrolysis Citric acid cycle (also called the Krebs cycle) cyclic adenosine monophosphate (cAMP) Phosphagen Thioesters are related to ATP External link ATP and biological energy ...

Amino acid

...ndard . Proline is the only proteinogenic amino acid whose side group is cyclic and links to the a-amino group, forming a secondary amino group. Formerly,...in). 1-Aminocyclopropane-1-carboxylic acid ( ACC ) is a small disubstituted cyclic amino acid and a key intermediate in the production of the plant hormone ...

Biomechanics

...pation, or hysteresis, between the loading and unloading of the tissue during mechanical tests. Some soft tissues can be preconditioned by repetitive cyclic loading to the extent where the stress-strain curves for the loading and unloading portions of the tests nearly overlap. Nonlinear Theories H...

Dialysis

...s of peritoneal dialysis. Continuous ambulatory peritoneal dialysis (CAPD), the most common type, needs no machine and can be done at home. Continuous cyclic peritoneal dialysis (CCPD) uses a machine and is usually performed at night when the person is sleeping. Intermittent peritoneal dialysis (IPD) uses t...

Enzyme

....qmul.ac.uk/iubmb/enzyme/ Enzymes and classes of enzyme Adenylate cyclase : participate in signal transduction by converting ATP into cyclic AMP Alcohol dehydrogenase : breaks down alcohols to aldehydes in human liver; creates alcohol in yeast fermentation Alkaline phosphatas...

Glucose

...glycosylation ) reduces or destroys the function of many enzymes . The low rate of glycosylation is due to glucose's preference for the less reactive cyclic isomer . Nevertheless, many of the long-term complications of diabetes (e.g., blindness, kidney failure, and peripheral neuropathy) are probably du...
Cyclic in Biological Dictionary

Rhodopsin

...ngles, watch music videos, listen to free streaming mp3s, & read ... cyclic Pathway of Rhodopsin and its Relationship to Hyperpolarization of the Rod ... Rhodopsin undergoes a cyclic decomposition and reconstitution in response to the ... Rhodopsin (RHO...

Photophosphorylation

...rylation is the process of creating ATP using a Proton gradient ... During cyclic Photophosphorylation the electrons are recycled, hence the name ... De...horylation in chloroplasts as a function of the ... I. Photosystem II cyclic Photophosphorylation Catalyzed by p-Phenylenediamine ... Electron transpo...

Phosphorylation

...rol is a necessary step in forming the ... Online Shopping at DirectTextBook.com - Save up to 80%, buy or rent. New and used books like Advances in cyclic Nucleotide and Protein Phosphorylation Research... Phosphorylation of p53 Protein in A549 Human Pulmonary Epithelial Cells Exposed to Asbestos ...

Monosaccharides

...bohydrates Monosaccharides for Immediate Energy Mental Fuel and... Monosaccharides in solution exist as equilbrium mixtures of the straight and cyclic forms. ... Sugars ( monosaccharides , dissacharides and polysaccharides which ... ...

Cyclic electron flow

... (Redirected from cyclic electron flow ) Jump to: navigation, sear...ytochrome b6f to PSI. ... Aspects of the topic cyclic - electron - flow are discussed in the following ...in a new window. Photosynthesis-Calvin Cycle and cyclic Electron Flow ... photosynthesis Calvi...

Chloroplasts

...loroplasts in eukaryotes. ... The Chloroplast Genome. The genome of the chloroplasts found in Marchantia ... Chemiosmosis in Chloroplasts . cyclic Photophosphorylation. Pseudocyclic Photophosphorylation ... Link to page on chloroplast structure. ... Chloroplast K-12 experiments & bac...
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