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Cryptococcus in Medical News

Predicting fatal fungal infections

...ilable. A major cause of fungal meningitis is cryptococcus neoformans , a yeast-like fungus commonly found in...ppings. Virtually everyone has been infected with cryptococcus neoformans , but a healthy immune system keeps the... The risk of developing fungal meningitis from cryptococcus neoformans rises dramatically when people have we...

JCI online early table of contents: Feb. 7, 2008

...mson and colleagues, at the University of Illinois at Chicago, has identified autophagy as a new virulence-associated trait and survival mechanism for cryptococcus neoformans a fungal pathogen that commonly infects immunocompromised individuals, such as those with HIV. In the study, a mutant form of C. neofor...

Notch-ing glucose into place

...n the membrane and fails to become activated. Similarities between rumi and some sugar-modifying enzymes involved in a particular process in the yeast cryptococcus neoformans prompted Bellen to ask if loss of rumi affects the manner in which glucose molecules are added to the Notch protein. He and his colleag...

Einstein scientists treat cancer as an infectious disease -- with promising results

...nfection-related diseases. In a series of animal studies beginning in 2001, she successfully used radioimmunotherapy against the major fungal pathogen cryptococcus neoformans and against a streptococcal bacterium responsible for pneumonia. Last year, she and her colleagues showed that radioimmunotherapy could hel...

Researchers Develop Basis For Experimental Melanoma Treatment

... biology of the skin pigment melanin to better understand why its synthesis plays a role in the process whereby certain yeast-like fungi, specifically cryptococcus neoformans, cause disease in some people. C. Neoformans can cause cryptococcosis, a potentially fatal fungal infection that can lead to inflammation o...

Sex Played A Vital Role For Evolution Of Infectious Diseases

...ersity Medical Center have reported//. The fungus, cryptococcus gattii, is normally restricted to the tropics and ...nd porpoises. The potentially life-threatening cryptococcus neoformans invades the central nervous system to c... It is suspected that the infectious propagules of cryptococcus are airborne spores, Heitman said. Such spores are...
Cryptococcus in Medical Technology

Scientific Results Presented At ECCMID Demonstrate Well- Differentiated Profile of Basilea's Two Phase III Anti- infective Compounds

...her azole drugs (P1978). Potent activity against candida is further supported by data from a thorough analysis in animal models (P1950). Additionally, cryptococcus neoformans, a yeast species not typically covered by the candin class, is highly susceptible to isavuconazole (P1977). In animal models of aspergill...
Cryptococcus in Medical Products

Crypto-LA® Cryptococcal Antigen Test

Description:... Latex agglutination slide test for the qualitative or quantitative determination of cryptococcus neoformans antigen in CSF and serum....
Company:Inverness Medical Innovations
Cryptococcus in Biological News

Scientists discover how deadly fungus protects itself

...ournal Proceedings of the National Academy of Sciences ( PNAS ), may help scientists develop new therapies or vaccines against infections caused by cryptococcus neoformans . These fungal infections occur most commonly in those with compromised immune systems ─ especially AIDS patients and transplant pati...

Gamma interferon could aid fight against fungal infections

...s completely from infected tissues but it has great potential to add to conventional therapy. When gamma interferon was given to mice infected with cryptococcus along with amphotericin B, a standard antifungal treatment, the rate of cure was significantly higher than using one therapy alone. We need to look at...

New recommendations against a major opportunistic infection -- cryptococcosis

...sults, the authors propose a modification in the therapeutic treatment of individuals suffering from cryptococcosis. Caused by a microscopic fungus, cryptococcus neoformans, cryptococcosis affects immunosuppressed individuals, most of whom are infected by HIV, but who also suffer from other immunological disord...

Stopping plants from getting sick

...usands of genes on my desktop computer." Kronstad is now using his NSERC-funded research as a foundation to fight an outbreak of the yeast fungus cryptococcus on Vancouver Island, applying his research on plants to help investigate how this yeast causes pneumonia, meningitis and other illnesses in humans and...

Same-sex mating by fungi spawned infection outbreak, evidence suggests

...iversity Medical Center have reported. The fungus, cryptococcus gattii, is normally restricted to the tropics and ...y related to the more widespread infectious yeast, cryptococcus neoformans. The potentially life-threatening C. ne..."It is suspected that the infectious propagules of cryptococcus are airborne spores," Heitman said. "Such spores a...

Program finds lost genes in nematode genome

... Brent Brent has brought his bioinformatics skills to many genomes, including those of mammals, other nematode species and most recently the fungus cryptococcus neoformans. Brent's approach to gene prediction stands traditional genome annotation on its head because it starts with a computer analysis of the gen...

Same-Sex Mating Discovered in a Toxic Fungus

...5, issue of Nature, the researchers reported that, in the infectious fungus cryptococcus neoformans, members of the same "sex" can mate and produce offspring. Infec... usually exist in an approximately one-to-one sex ratio," Lin said. "Yet in cryptococcus neoformans, one mating type predominates, leaving them with apparently few ...

Light therapy may combat fungal infections, new evidence suggests

...arks infection, the researchers said. The discovery in the human pathogen cryptococcus neoformans further suggests that light therapy, in combination with anti-fu...possible for certain fungal sinus infections, he added. The finding that cryptococcus shares its light-sensing mechanism with other distantly related fungi also ...

Scientists decipher genome of fungus that can cause life-threatening infections

...ered the genomes of two closely related strains of cryptococcus neoformans, a fungus whose importance as a human p...ungal pathogenesis. Since the 1980s, the number of cryptococcus infections has increased sharply ?mainly among peo...me rearrangements often observed between different cryptococcus isolates. TIGR's Fraser says the...
Cryptococcus in Biological Dictionary

Mating type

...ore 1984, A2 mating type had only been detected in Mexico, the possible ... Impact of Mating Type , Serotype, and Ploidy on the Virulence of cryptococcus neoformans. ... Identification of Mating Type Genes in the Bipolar Basidiomycetous Yeast ... ( mating type ) amongst a worldwide collection o...
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