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Cotinine in Medical News

Urine test may determine if a smoker is at risk for lung cancer

... increased risk of lung cancer after taking into account the effect of number of cigarettes per day, number of years of smoking, and urinary levels of cotinine on lung cancer risk. Levels of nicotine in the urine were also calculated. Those with the highest levels of nicotine and NNAL had an 8.5-fold incr...

Urine Test Could Gauge Smokers' Lung Cancer Risk

...r known as NNAL could predict cases of lung cancer. The team found that the third of smokers who had the highest levels of NNAL and a marker called cotinine were 8.5 times more likely to develop lung cancer than those with levels in the lowest third and similar histories of smoking. "We compared apples ...

Secondhand Smoke Affecting Millions of New Yorkers

...hat 57 percent of nonsmoking adults in New York City had elevated levels of cotinine in their blood, compared with 45 percent of nonsmokers nationwide. Cotinine...moking New Yorkers, 69 percent of Asian adults are thought to have elevated cotinine levels, putting them at the top of the list, according to the study. Lower...

Blood tests reveal tobacco smoke residues in non-smoking New Yorkers

...of non-smoking New Yorkers have elevated levels of cotinine in their blood meaning that they were recently ex...% of adult New Yorkers (2.5 million) have elevated cotinine levels, compared to 45% of adults nationwide a fi...Asian adults were the most likely to have elevated cotinine levels (69%). Studies from other parts of the coun...

Secondhand Smoke Linked to Dementia

...The researchers found that people with the highest cotinine levels had a 44 percent increased risk of cognitiv...e impairment, compared with people with the lowest cotinine levels. And, while the risk of impairment was lower in people with lower cotinine levels, the risk was still significant. "We kno...

Smokers putting their loved ones at risk of heart attacks

...sh Regional Heart Study by measuring the levels of cotinine - a compound carried in the blood - at two time points 20 years apart. A blood cotinine level above 0.7ng/mL is associated with a 40% incr...hers found that while in 1978-80, 73% of men had a cotinine level above 0.7ng/mL, by 1998-2000 that proportion...

Avoiding secondhand smoke during pregnancy

...the baby's health were also measured. To accurately determine ETS exposure, cotinine levels in the mother's saliva were measured. cotinine is a widely accepted biomarker for tobacco exposure. Twenty-seven percen...

Study strengthens link between tobacco smoke and behavioral problems in boys with asthma

...e of Medicine. Investigators also measured the cotinine levels in the children's blood. cotinine is a byproduct, or metabolite, of nicotine and is ...obacco smoke exposure. The researchers compared cotinine levels to behavioral patterns observed in the chil...

Newborns exposed to maternal smoking more irritable, difficult to soothe

...uring cotinine, the primary metabolite of nicotine, in the mother's saliva. cotinine is readily passed from mother to infant, with the baby absorbing nearly as ...hird trimester. Postnatal smoke exposure was quantified by infant saliva cotinine levels. All infants were then assessed using the Neonatal Intensive Care Un...

Moms' Smoking Linked to Increased Risk of Birth Defects

...arch is the first time we've been able to measure something -- in this case cotinine -- and determine the risk of smoking during pregnancy for oral-facial birth...more babies a healthy start in life," Dr. Howse continued. "Mid-Pregnancy cotinine and Risks of Orofacial Clefts and Neural Tube Defects" by Shaw's California...
Cotinine in Medical Dictionary

Nicotine

... Original Article from The New England Journal of Medicine -- Transdermal Nicotine for Active Ulcerative Colitis ... and plasma nicotine and cotinine ... A man about to use a piece of nicotine gum. ... The nicotine is delivered to the bloodstream via absorption by the tissues of the mouth....
Cotinine in Biological News

Skin color clue to nicotine dependence

...e (FTND). Researchers also measured the smokers' cotinine levels. cotinine is a metabolic byproduct of nicotine that can be u... of smoking -- cigarettes per day, FTND score, and cotinine levels -- along with a host of other variables inc...

Children of smokers have more than 5 times higher levels of a nicotine toxin

...as found to have the biggest independent effect on cotinine in the urine – quadrupling it. Having a smoking fa...ociated with increased amounts of cotinine. cotinine was measured in 100 urine samples taken from infan...maller rooms and inadequate heating. ‘Higher cotinine levels in colder times of year may be a reflection...

Indicators for risk of heart disease are higher in passive smokers

... American Heart Association, measured the level of cotinine in participants' blood, rather than relying on par...' self-reporting of exposure to second-hand smoke. cotinine is the major metabolite of nicotine that indicates... is highly specific for tobacco smoke, blood serum cotinine levels track exposure to tobacco smoke and its tox...

Blood test predicts success of quitting smoking using the nicotine patch

...sity of Pennsylvania Transdisciplinary Tobacco Use Research Center. When nicotine is metabolized ?or broken down in the body ?it turns to cotinine. cotinine is then metabolized to 3-hydroxycotinine (3-HC) by an enzyme in the liver. This study measured the ratio of these two breakdown products of nicotine a...

Environmental tobacco smoke linked to behavior problems in children and pre-teens

...ental tobacco smoke, Dr. Yolton measured levels of cotinine in the children's blood. cotinine is a substance produced when nicotine is broken do...posure. Dr. Yolton found a relationship between cotinine levels and increases in acting out; increases in h...
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