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Coreceptor in Medical News

Mixed HIV Coreceptor Use Associated With Lower CD4 Count

Patients who have been heavily treated with antiretroviral drugs have a high proportion of viral strains that can use two types of chemokine receptors to infect cells, according// to a study published in the February 15th edition of Clinical Infectious Diseases. The researchers, led by Timot...

ASP announces 2008 T. Franklin Williams Scholars

...tric Hematology Research Award Amie L. Meditz, MD University of Colorado School of Medicine Influence of Sex Steroids and Aging on HIV-1Chemokine coreceptor Expression in Women ASP-Infectious Diseases Society of America Young Investigator Award in Geriatrcs Lisa M. Nanovic, DO University of Wisconsin ...
Coreceptor in Medical Technology

Schering-Plough Expands Vicriviroc Phase II Study in Treatment-Naive Patients With HIV

...1A. "Risk Factors" in the Company's first quarter 2009 10-Q, filed May 1, 2009. Endnotes 1 Hoffmann C (2007) The epidemiology of HIV coreceptor tropism. Eur J Med Res (2007) 12: 385-390. 2 Atazanavir sulfate is a Bristol-Myers Squibb Company prescription medicine. Please see the atazanav...

Analysis of Long-Term Vicriviroc Data Provides Evidence of Sustained Viral Suppression, Increased CD4 Cell Counts and Tolerability in Treatment-Experienced HIV-Infected Patients

...cted, treatment-experienced patients: AIDS Clinical Trials Group 5211. J Infect Dis. 2007;196:304-312. (5) Hoffmann C (2007) The epidemiology of HIV coreceptor tropism. Eur J Med Res (2007) 12: 385-390. (6) Atazanavir sulfate is a Bristol-Myers Squibb Company prescription medicine. Please see the atazanavir...

Schering-Plough Initiates Phase II Study With Vicriviroc in Treatment-Naive HIV-Infected Patients

...sion filings, including Part I, Item 1A. "Risk Factors" in Schering-Plough's 2007 10-K/A. References 1 Hoffmann C (2007) The epidemiology of HIV coreceptor tropism. Eur J Med Res (2007) 12: 385-390. 2 Atazanavir sulfate is a Bristol-Myers Squibb Company prescription medicine. Please see the atazan...

Progenics Announces Positive Results in Clinical Trial of Novel HIV Therapy

...ive care. In the area of HIV infection, the Company is developing the viral-entry inhibitor PRO 140, a humanized monoclonal antibody targeting the HIV coreceptor CCR5, which has completed phase 1b clinical studies with positive results. In addition, the Company is conducting research on ProVax, a novel prophyla...
Coreceptor in Medical Definition

Thymocyte

...cell receptor capable of binding MHC. The T cell receptor requires CD8 as a coreceptor to bind to MHC class I, and CD4 as a coreceptor to bind MHC class II. At this stage thymocytes upregulate both CD4 and CD8,...
Coreceptor in Biological News

Insects evolved radically different strategy to smell

...rth, says Vosshall. They are composed of two proteins that work in tandem with one another: an olfactory receptor and its coreceptor, Or83b. While the coreceptor is common to every ion channel, the olfactory receptor is unique. Together, they form the olfactory receptor complex. Vosshall and Touhara specificall...

New component of the 'brakes' on nerve regeneration found

...," they wrote. ### Jong Bae Park, Glenn Yiu, Shinjiro Kaneko, Jing Wang, Jufang Chang, and Zhigang He: "A TNF Receptor Family Member, TROY, Is a coreceptor with Nogo Receptor in Mediating the Inhibitory Activity of Myelin Inhibitors" Zhaohui Shao, Jeffrey L. Browning, Xinhua Lee, Martin L. Scott, Svelt...
Coreceptor in Biological Technology

New Test from Quest Diagnostics Helps Physicians Choose HIV Antiretroviral Therapy in Patients with History of Drug Resistance

...t class of HIV antiretroviral therapies. The HIV-1 coreceptor Tropism Test, which reports results in approximate...ially better spent on a different drug." HIV coreceptor tropism refers to the preference of strains of HIV...romoting disease progression, based on the type of coreceptor on the cell's surface. The newest class of antire...

Researchers decode viral process that prepares cells for HIV infection

...CD4 T-cells taken from blood and infected with HIV. The researchers found that when HIV binds to the cell surface, it uses a molecule called chemokine coreceptor CXCR4 to send a signal that activates a cell protein known as cofilin. The protein is then used to cut through the cortical actin cytoskeleton (the ci...

Medical Policy Guideline for Trofile(TM) Established By Wellpoint, Inc.

...ve evidence of ongoing HIV-1 viral replication. Further, these guidelines confirm that Trofile is the only assay approved by Wellpoint for determining coreceptor tropism. Wellpoint has developed medical policies and guidelines that serve as some of the guidelines for coverage decisions by individual plans. "T...
Coreceptor in Biological Dictionary

Syncytium

...lls and SupT1 or HIV-1-infected U937 ... FIV mediates syncytium formation. ... as measured by syncytium formation is given ... CXCR4 is also a coreceptor for the syncytium -inducing strains of HIV (24) ... Syncytium - Wikipedia, the free encyclopedia ... syncytium - definition of syncytium in ...
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