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Conjugation in Medical News

SAFC Pharma's St. Louis HPAPI Conjugates Facility Receives SafeBridge Certification

...ly potent active pharmaceutical ingredient (HPAPI) conjugation suite, by SafeBridge (R) Consultants, Inc. for th...suite, commissioned in September 2008, enables the conjugation of Highly Potent Active Pharmaceutical Ingredients...ning SafeBridge certification status for our HPAPI conjugation suite provides our customers with complete confide...

Nektar Announces UCB's Cimzia(R) Approved by U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis

... developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise ha...clinical or commercial success with any other PEGylated or advanced polymer conjugation products, and (3) other important risks and uncertainties set forth in the ...

Nektar Therapeutics to Present at the Deutsche Bank 34th Annual Health Care Conference in Boston

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading biop...

Nektar to Announce Financial Results for the First Quarter of 2009 on Wednesday, May 6, 2009, After Close of U.S.-Based Financial Markets

...conference call. About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading bioph...

NKTR-105 Demonstrates Superior Antitumor Activity and Improved Pharmacokinetics Over Docetaxel in Preclinical Studies Presented at AACR

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading bioph...

Mersana's Second Development Candidate, XMT-1107, Shows Superior Pharmacokinetics and Anti-Tumor Activity in Studies Presented at American Association of Cancer Research Meeting

...on, Mersana CEO. "Earlier drugs in this class showed promising activity in the clinic but were discontinued due to reversible neurological toxicity. conjugation of our novel fumagillin 'warhead' to Fleximer using a specific linker technology reduces CNS exposure in animal models to below detection limits. We ...

Dosing Begins in Phase 1 Clinical Study Evaluating NKTR-105 in Cancer Patients With Refractory Solid Tumors

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading biop...

SAFC Pharma Commissions HPAPI Conjugates Facility at St. Louis

...s to support oncology drug development. The 600-sq ft suite will enable the conjugation of HPAPIs to a variety of targeted delivery molecules, including monoclonal... most potent) while the St. Louis site has more than 30 years experience in conjugation technology. "The HPAPI market has grown at a high double-digit pace; the ...

SAFC Pharma(TM) Commits to Major Expansion of High Potency API Production at Madison Site

...cluding a recently completed $4.5 million extension of its cGMP pilot plant and kilo-lab capacity, and operations have begun at its new biologic-HPAPI conjugation suite in St. Louis, Mo. SAFC Pharma has also invested in a major facility in Jerusalem, Israel, for large-scale production of bacterial and fungal fer...

SAFC Pharma Expands Its Pharmorphix Solid State Chemistry Services

...acity, respectively, at Arklow, Ireland and Buchs, Switzerland, a $29 million potent-fermentation expansion in Jerusalem, Israel and a high-potent API conjugation suite at its St Louis, MO manufacturing campus. About SAFC: SAFC(R) is the custom manufacturing and services group within Sigma-Aldrich that focuses...
Conjugation in Medical Products

Coat-Block-Run Conjugation Kit pH 8-11

Description: Gold Labeling kit for antibodies, the Coat-Block-Run Conjugation Kit pH 8-11; contains 1 bottle each of 20 nm and 40 nm Naked Gold...
Company:BioAssay Works, L.L.C.

Coat-Block-Run Conjugation Kit pH 5-8

Description: Gold Labeling kit for antibodies, the Coat-Block-Run Conjugation Kit pH 5-8; contains 1 bottle each of 20 nm and 40 nm Naked Gold...
Company:BioAssay Works, L.L.C.

Custom Conjugation

Description: Custom Conjugation Services...
Company:BioAssay Works, L.L.C.

Iso-Electric Determination Kit

Description:... Iso-Electric Determination Kit; contains 1 bottle of 40 nm Naked Gold Iso-Electric Determination Kit to optimize gold conjugation of antibodies...
Company:BioAssay Works, L.L.C.

Unconjugated Estriol, Ultra-Sensitive EIA Test

Description:...a late-gestational peak which is ~2-3 orders of magnitude greater than non-pregnant levels [1,2]. In the maternal circulation, estriol undergoes rapid conjugation in the liver followed by urinary excretion with a half-life of ~20 minutes [2]. Since normal estriol production depends on an intact maternal-placenta...
Company:Diagnostic Systems Laboratories, Inc.

Unconjugated Estriol, Ultra-Sensitive RIA Test

Description:...a late-gestational peak which is ~2-3 orders of magnitude greater than non-pregnant levels [1,2]. In the maternal circulation, estriol undergoes rapid conjugation in the liver followed by urinary excretion with a half-life of ~20 minutes [2]. Since normal estriol production depends on an intact maternal-placenta...
Company:Diagnostic Systems Laboratories, Inc.
Conjugation in Biological News

A paradigm shift in immune response regulation

...as been gradually pieced together to show that modifications in the cell protein - including the addition of phosphate groups (phosphorylation) or the conjugation of small modifier ubiquitin (ubiquitination) - play a central role in controlling the immune system. Scientists at Frankfurt's Goethe University l...

Researchers develop way to calculate speed of bacterial sex

...t its impact in nature, current computer models of conjugation were pretty basic," said Ginn. UC-Davis researcher...g a previously established conceptual framework of conjugation processes in an isolated environment, researchers ... new mathematical model of bacterial transport and conjugation that focused on subsurface bacteria colonizing sur...

'Failed' experiment yields a biocontrol agent that doesn't trigger antibiotic resistance

...f bacteria that could suppress over-replication of the key plasmid. This so-called "Trojan horse" could then be used to spread the killer plasmid via conjugation to targeted bacterial pathogens that lacked the ability to resist over-replication. "We harnessed this plasmid," thought Filutowicz. "Now, how can...

Scientists design simple dipstick test for cocaine, other drugs

...n. The appropriate aptamer-linked nanoparticle aggregates are placed on the conjugation pad, streptavidin is applied as a thin line to the membrane pad, and the de...le, the wicking pad carries the fluid to the nanoparticle aggregates on the conjugation pad. The rehydrated aggregates then migrate to the edge of the membrane, wh...

MSKCC researchers uncover structure of key protein complex in cells

... instead appears to alter their function in different ways, perhaps even by preventing ubiquitin tagging. Still, there are enough similarities between conjugation of SUMO and ubiquitin that the latest findings could help researchers understand both. "The structural network has revealed a mechanism that may be im...
Conjugation in Biological Technology

Nektar Therapeutics to Present at the BMO Capital Markets 9th Annual Focus on Healthcare Conference in New York City

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading bioph...

Nektar to Announce Financial Results for the Second Quarter of 2009 on Tuesday, August 4, 2009, After Close of U.S.-Based Financial Markets

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading bioph...

Celsis Outlines the Top Five Advantages of Cryo-plateable Hepatocytes

... and download the following poster presentations from Celsis' experts: The Effects of Cryopreservation on P450 Oxidation and Phase II conjugation Activity A High Throughput Screening Assay for Hepatotoxicity Using Cryopreserved Hepatocytes Comparison of Fresh and Cryo Cynomolgus ...

Nektar Therapeutics Promotes Lorianne Masuoka, M.D. to Chief Medical Officer

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading bioph...

Sangart, Inc. Completes Series F Funding Round

...tics The MP4 molecule is the basis for Sangart's oxygen therapeutic product platform. The MP4 molecule is created using unique polyethylene glycol conjugation with human hemoglobin and was specifically designed to the optimal molecular size, viscosity, oxygen affinity and diffusion potential to target oxygen...

Nektar Therapeutics' President and CEO, Howard W. Robin, to Present at the 29th Annual Cowen and Company Healthcare Conference in Boston

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading biop...

Nektar to Announce Year-End 2008 Financial Results on Wednesday, February 25, 2009 After Close of U.S.-Based Financial Markets

...rence call. About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading bioph...

Nektar Announces Retirement of Irwin Lerner from Board of Directors

...to Nektar." About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading bioph...

First Patient Dosed in Phase 2 Clinical Trial of NKTR-102 in Ovarian Cancer

... 50 hours). About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading bioph...

Sangart, Inc. Announces Key Executive Appointments and Company Restructuring

...out Hemospan(R) Sangart's lead product candidate, Hemospan(R) is an oxygen therapeutic product that is created using unique polyethylene glycol conjugation with human hemoglobin. Hemospan(R) was specifically designed to the optimal molecular size, viscosity, oxygen affinity and diffusion potential to tar...
Conjugation in Biological Products

Peptide Conjugation (OVA, BSA, KLH, Thyroglobulin) from Covance Research Products, Inc

Description: Quality ISO 9001:2000 Certified USDA Research Registered OLAW Assured AAALAC Accredited All Precedures Validated, SOP's Training AALAS Certified Technicians Documentation GLP Process for All Procedures GLP Documentation Upon Request Focus CRP is your one stop shopping point for all your cus...
Company:Covance Research Products, Inc

Custom Conjugation Services from SoluLink

Description: ...
Company:SoluLink

Custom Conjugation Services from SoluLink

Description: Conjugation services for Antibodies, Proteins, Oligos, Peptides, Beads, bioconjugation, antibody-oligonucleotide, LNA peptide, LNA protein, LNA antibody, HRP, Alkaline phosphatase, phycoerythrin, FITC, antibody enzyme conjugate...
Company:SoluLink

Custom Production Service - Conjugation from AbD Serotec

Description: Custom Production Service - Conjugation Alkaline Phosphatase Conjugation Horseradish Peroxidase Conjugation Biotin Conjugation Fluorescein Isothiocyanate Conjugation R. Phycoerythrin Conjugation Rhodamine Conjugation Allophycocyanin Conjugation Alexa Fluor 488 Conjugation Alexa Fluor 647...
Company:AbD Serotec

SureLINK HRP Conjugation Kit from KPL

Description: SureLINK HRP Conjugation Kits are based on well-established periodate chemistry, yielding protein conjugates that are consistent and reproducible. This kit contains all reagents required to conjugate your protein or antibody, including ready-to-use buffers and an optimized storage buffer. Activate...
Company:KPL

Imject Maleimide Conjugation Buffer from Pierce Biotechnology, Inc.

Description: Pierce offers maleimide activated carrier proteins to simplify the production of hapten-carrier conjugates. Imject Maleimide Activated Carrier Proteins are commonly used carriers that have been preactivated with a heterobifunctional cross-linker (Sulfo-SMCC). This activation results in a stable, su...
Company:Pierce Biotechnology, Inc.

Protein Conjugation Services from ARVYS Proteins, Inc.

Description: Biotin or fluorescent labels can be attached and the stoichiometry of protein labeling determined....
Company:ARVYS Proteins, Inc.

Horseradish Peroxidase (HRP) Conjugation Kit For labeling Antigens/Antibodies (Reaction Time 2 hr) from Alpha Diagnostic International Inc

Description: ...
Company:

QXL 520 C2 maleimide from AnaSpec

Description:...re increasingly preferred for labeling peptides and nucleotides because they give better resolution in HPLC purification that is often required in the conjugation processes. 5-TAMRA is more often used than 6-TAMRA for labeling peptides and proteins. 6-TAMRA is predominately used for labeling nucleotides and sequ...
Company:AnaSpec

Phospho-peptide Antibody from Proteintech Group, Inc.

Description:...cid MS-spec check purity above 90%, 20 mg will be returned to customer conjugation of peptide to KLH protein Rabbits x 2, Maintenance 102 days/each...Free ELISA x1/each Purification of antiserum over antigen (30 ml) conjugation of antigen peptide to Sepharose, 3 ml column Written report of antibody ...
Company:Proteintech Group, Inc.

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Conjugation in Biological Definition

Bacterial conjugation

Bacterial conjugation is the often regarded as the bacterial equivalent of sexual reproduction or mating ; however it is not actually sexual as it does not involve the fusing of gametes and the creation of a zygote , it is merely the exchange of genetic information. In order to perform c...

Reproduction

... this domestic labor has historically been the responsibility of women; thus it is of particular interest in feminist economics. See also conjugation sexual intercourse father paternity mother custody self-replication reproductive technology fertility issues ...

Bacterium

...and viral DNA from one cell to another via bacteriophage) and; bacterial conjugation (the transfer of DNA from one bacterial cell to another via a special protein structure called a conjugation pilus ). Bacteria, having acquired DNA from any of these events, can ...

Bacterium

...and viral DNA from one cell to another via bacteriophage) and; bacterial conjugation (the transfer of DNA from one bacterial cell to another via a special protein structure called a conjugation pilus ). Bacteria, having acquired DNA from any of these events, can ...

Hfr cell

...en F ) integrated into its genomic DNA. Hfr is the abbreviation for high frequency recombination . Unlike a normal F+ cell, hfr strains will, upon conjugation with a F- cell, attempt to transfer their entire DNA through the pilus to the F- cell. As fragile a structure as a pilus will, however, likely bre...

Plasmid

...asmids contain so-called tra-genes , which perform the complex process of conjugation , the sexual transfer of plasmids to another bacterium (Fig. 4). Non-conju... Fertility-(F)plasmids , which contain tra-genes. They are capable of conjugation . Resistance-(R)plasmids , which contain genes that can build a resista...

Reproduction

... this domestic labor has historically been the responsibility of women; thus it is of particular interest in feminist economics. See also conjugation sexual intercourse father paternity mother custody self-replication reproductive technology fertility issues ...
Conjugation in Biological Dictionary

Conjugation

Bacterial conjugation is the transfer of genetic material between bacteria through direct cell-to-cell contact. Discovered in 1946 by Joshua Lederberg and Edward Tatum, conjugation is a mechanism of horizontal gene... inner automorphism, a type of conjugation homomorphism. conjugacy ...

Bacterial conjugation

Bacterial conjugation is the transfer of genetic material between bacteria through direct cell-to-cell contact. Discovered in 1946 by Joshua Lederberg and Edward Tatum, conjugation is a... Bacterial conjugation Bacterial conjugation is the transfer of genetic material between...

Streptavidin

...eric protein purified from the bacterium ... This Cell Signaling Technology product is useful for the detection of biotinylated proteins (1,2). conjugation of horseradish peroxidase (HRP) to streptavidin is ... A 52.8 kDa non-glycosylated protein with a very high affinity for biotin. ... unit is de...

Micronucleus

... A micronucleus is the smaller nucleus in ciliate protozoans, such as the paramecium. In fission it divides by mitosis, and in conjugation furnishes the pairing of gamete nuclei, by whose reciprocal fusion a zygote nucleus is formed, which gives rise to the macronuclei and micronuc...

Mating type

...only The mating type alleles of T. thermophila are unusual in that they ... Mating type is determined during macronuclear development at conjugation by a ... Information about Mating type in the free online English ... type (redirected from Mating type ) Also found in: Medical, Financi...

Macronucleus

...n suctorian and ciliate protozoans (e.g., Paramecium). The macronucleus is associated with one or more smaller micronuclei, which are necessary for conjugation and autogamy (reproduction by exchange between the nuclei of different individuals and of the same individuals,... macronucleus synonyms. mac...

Hfr cell

...reviation for high frequency recombination, which was first characterized by Luca Cavalli-Sforza. Unlike a normal F+ cell , hfr strains will, upon conjugation with a F− cell , attempt to transfer their entire DNA through the mating bridge, not to be confused... Aspects of the topic Hfr - cell are di...

Gene mapping

..., mapping ,biological,biolog y dictionary,biology terminology,biology terms,biology abbreviations ... A gene mapping technique in which bacterial conjugation ... U.S. National Coordination Programe for Swine Gene Mapping ... U.S. Pig Gene Mapping Coordination Program Shared Resources. Illumina P...

Cotransduction

...uction frequency may be converted to physical distance by using the ... The cotransduction data (Table 1) and ... ... by plasmid FP5-mediated conjugation and by cotransduction with the generalized ... Cotransduction of the car and ilv loci could not be detected. ... Definition of cotransducti...

Conjugation tube

... ... Watch this video in a new window. Bacterial conjugation . Hello, you either have JavaScript turned off or ... conjugation , tube ,biological ,biology dictionary,biology ter...inology,biology terms,biology abbreviations ... A conjugation tube ; a hollow hair-like appendage of ... Wh...
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