Duane Reade Holdings, Inc. Announces Pricing of Offering of 11.75% Senior Secured Notes Due 2015

...rs pursuant to an optional redemption notice to be given at the closing date of the offering of the Notes. The closing of the Notes offering is conditioned upon, among other things, (i) all conditions precedent (including, without limitation, the funding of the Equity Investment) to the Offers, other than...

Duane Reade Holdings, Inc. Amends Terms and Extends Deadlines for Previously Announced Cash Tender Offers for Senior Secured Floating Rate Notes and Senior Subordinated Notes

...read in its entirety. The Offers and Solicitations of Consents are conditioned upon, among other things, (i) the funding of the $125 million preferred equ...urchase. In addition, the Equity Investment and the New Notes Offering are conditioned on the successful completion of each other and other conditions precedent s...

Hisamitsu Pharmaceutical Co., Inc. Begins Tender Offer for All Outstanding Shares of Noven Pharmaceuticals, Inc.

...cable rules and regulations of the SEC. The closing of the tender offer is conditioned on the tender of a majority of the outstanding shares of Noven's common stock on a fully diluted basis. The closing is also conditioned on clearance under the Hart-Scott-Rodino Antitrust Improvements Act and oth...

Gold's Gym Debunks America's Most Common Fitness Myths

...antee you a six-pack. FACT: There is no such thing as "spot reduction," but there is such a thing as spot conditioning. Muscles can be conditioned by training and focusing on them, but without burning the fat covering your abdomen, you'll never get that washboard stomach. MYTH #2:...

Duane Reade Holdings, Inc. Announces Cash Tender Offers for Senior Secured Floating Rate Notes and Senior Subordinated Notes and Solicitation of Consents to Related Indentures

...09, but not thereafter. The Offers and solicitations of consents are conditioned upon, among other things, (i) the funding of a $125 million preferred equit...rchase. In addition, the Equity Investment and the New Notes Offerings are conditioned on the successful completion of each other and other conditions precedent s...

Johnson & Johnson and Elan Corporation plc Announce Definitive Agreement for Alzheimer's Immunotherapy Program and Equity Investment

...mp; Johnson and Elan have each approved the transaction, which represents the culmination of an in-depth strategic review by Elan. The transaction is conditioned on clearance under the Hart-Scott-Rodino Antitrust Improvements Act and other customary closing conditions. Elan will host an analyst call at 8:...

The Crohn's & Colitis Foundation and Procter & Gamble Pharmaceuticals Announce 2009 Celebrating UC Success Contest Winners

...ven the nickname "semi-colon," and received a statue of a man thinking on a toilet, with a slogan that read "Wherever I go; I think of you." After his conditioned worsened and he required surgery, his children referred to his ostomy bag as "Oscar the ostomy" or "Oscar the pouch," and his sister brought his exten...

Carrier Increases Energy Efficiency at Hartford Hospital

...the hospital's north campus, installing a Carrier Comfort Network(R) (CCN) controls system which allowed for automatic adjustments, precisely matching conditioned air delivery to actual building conditions. The controls technology upgrade along with a new variable flow pumping system resulted in saving the hospi...

Delaware Urologic Associate's, Dr. Peter J. Muench, Presents Advances in Incontinence Treatment with a New Perspective and Outlook

...estioned the validity of old beliefs and wanted to treat male incontinence the same way they treated female incontinence. Previously, doctors had been conditioned to believe that the strong, narrow and muscular male pelvis could never allow the bladder to drop the way a female pelvis does. Questioning old belief...

EZ Breathe(R) Home Ventilation System Expels Allergens, Moisture and Smells

...EZ Breathe system only costs $2-$4 per month to operate Balanced : Unlike other systems, EZ Breathe expels stale air and replaces it with clean, conditioned air - and then circulates that fresh air throughout the home Cost effective : At a mere third of the cost of ERV and HRV systems, EZ Breathe is ...

Conditioned in Medical Technology

Nventa Presents Findings on Proprietary Toll-like Receptor 3 (TLR3) Agonist, Poly-ICR, at World Vaccine Congress

... agencies such as the FDA that are needed before products can be tested in clinical trials may not be obtained in a timely manner or at all or will be conditioned in a manner that would impair our ability to advance Poly-ICR; that Poly-ICR may not be found safe and effective after extensive clinical trials; that...

Multiple Clinical Trials of VELCADE(R) (Bortezomib) for Injection Based Therapies Demonstrate High Complete Remission Rates in Patients with Newly Diagnosed Multiple Myeloma

...ne cycle and on days 1 through 4 for cycles two through four. Cyclophosphamide at 3 g/m2 and G-CSF were used to harvest stem cells. Patients were then conditioned with two courses of melphalan at 100 mg/m2 (MEL100). Following SCT, patients received lenalidomide at 25 mg/day on days 1 through 21 plus prednisone a...

Nventa Announces Additional Positive Immunological Data From HspE7 Phase 1 Cervical Dysplasia Trial

...s can be tested in clinical trials; the possibility that such government agency approvals will not be obtained in a timely manner or at all or will be conditioned in a manner that would impair our ability to advance development; risks associated with the requirement that a drug candidate be found safe and effect...

Nventa Completes Safety Evaluation on Final Cohort in HspE7 Phase 1 Cervical Dysplasia Trial

...s can be tested in clinical trials; the possibility that such government agency approvals will not be obtained in a timely manner or at all or will be conditioned in a manner that would impair our ability to advance development; risks associated with the requirement that a drug be found safe and effective after ...

Nventa Announces Positive Interim Immunological Data From HspE7 Phase 1 Cervical Dysplasia Trial

...s can be tested in clinical trials; the possibility that such government agency approvals will not be obtained in a timely manner or at all or will be conditioned in a manner that would impair our ability to advance development; risks associated with the requirement that a drug be found safe and effective after ...

Nventa Enrolls and Initiates Dosing of Final Cohort in HspE7 Phase 1 Cervical Dysplasia Trial

...s can be tested in clinical trials; the possibility that such government agency approvals will not be obtained in a timely manner or at all or will be conditioned in a manner that would impair our ability to advance development; risks associated with the requirement that a drug be found safe and effective after ...

FASgen Announces a New Discovery in Obesity Research

...or of brain CPT-1 and produced in vivo results in mice of decreased feeding for three days and persistent weight loss of six days, with no evidence of conditioned taste aversion. See, "Pharmacological Stimulation of Brain Carnitine-Transerase-1 Decreases Food Intake and Body Weight," Ronnett, et al, Am J Physiol...

Nventa Announces Presentation of Positive HspE7 Data from NCI-Sponsored Clinical Trial in Cervical Dysplasia

...s can be tested in clinical trials; the possibility that such government agency approvals will not be obtained in a timely manner or at all or will be conditioned in a manner that would impair our ability to advance development; risks associated with the requirement that a drug be found safe and effective after ...

Conditioned in Medical Dictionary

Vaginismus

...penetration involved in gynecological examinations. This is the result of a conditioned reflex of the... Definition, causes, incidence, risk factors, symptoms,...are the two most common sexual dysfunctions in women. ... Vaginismus is a conditioned pain caused by involuntary spasm of the muscles ... Our Scientific ...

Sucrose

...cation Codeine Phosphate (Codeine Phosphate), drug uses, dosage, side ... These tablets also contain lactose and sucrose . ... ... separately conditioned to associate a Pavlovian cue with free sucrose pellets. ... Similarly, sucrose ingestion normalizes CRF levels in hypothalamus and amygdala ... ...

Conditioned in Biological News

SUNY Downstate researchers find that memory storage molecule preserves complex memories

...n. The findings are detailed in the December edition of PLoS Biology in a paper titled, "PKMzeta Maintains Spatial, Instrumental, and Classically conditioned Long-Term Memories." The paper is authored by Andre A. Fenton, PhD, associate professor of physiology and pharmacology, Todd C. Sacktor, MD, professor...

Where there's wildfire smoke, there's toxicity

...tissues are a matter of concern. "More aggressive measures to avoid smoke seem to deserve study, including distribution of masks and evacuation to air conditioned environments, and closure of non-smoke secured schools," said Sioutas, who holds the school's Fred Champion Professorship of Civil and Environmental E...

Moths with a nose for learning

... Much like Pavlov conditioned his dog to salivate in anticipation of food when a bell rang, insects can b...tand that the ringing of the bell meant food. In this case, the researchers conditioned a particular species of moth, Manduca sexta, to extend its proboscis in ant...

Lessons from the Iditarod

...ir ability to rapidly adapt to sustained strenuous exercise in 24-48 hours. conditioned dogs display most of the metabolic changes that are found in human enduranc...ume of oxygen to body weight per minute), the aerobic capacity of the fully conditioned sled dogs is estimated to be about twice that (300 ml/kg/min). Using...

Cocaine: How addiction develops

...increase their agility, the lab animals covered significantly greater running distances and preferentially frequented those places where they had been conditioned to be regularly administered the drug. If normal mice do not find drugs at the familiar places over a longer period of time, their addictive beha...

Metagenomics of skin reveals insights into the human microbiome

...novel drugs and treatments. It's not surprising that microbes play a vital role in human health and disease, says Segre. Unfortunately the public is conditioned to view microbes antagonistically, when in fact they may hold the key to a whole new array of therapeutic options. ...

Study confirms that low-calorie sweeteners are helpful in weight control

...rising obesity rates. The human desire for sweet taste is an innate reflex that is present at birth: it is not learned, it is not acquired, it is not conditioned and it is not going away anytime soon. This study oversimplifies the causes of obesity, said Beth Hubrich, a dietitian with the Calorie Control C...

It is important to demonstrate the influence of the microenvironment in the process of metastasis

... human colon cancer is cultured in the presence of conditioned media of primary cells from the liver after being stimulated with tumour cell conditioned media. With in vitro conditioned media, the aim is to imitate the environment of th...

Choosing dry or wet food for cats makes little difference

...owing the cat to eat in excess. The most effective thing you can do is be the one who determines how much your cat eats, Backus said. We have been conditioned to fat cats, but cats should have only between 18 percent to 20 percent body fat. ...

Uganda's mountain gorillas increase in number

...ue for Uganda annually by bringing paying travelers into the company of mountain gorillas. Four of the 30 family groups are habituated for tourism, or conditioned to tolerate the presence of humans for short durations. The other mountain gorilla stronghold is located just south of Bwindi Impenetrable Natio...

Conditioned in Biological Technology

Isolagen, Inc. Announces Receipt of Interim Order from Bankruptcy Court Approving DIP Motion

...ed by the Company and disseminated to all parties who are entitled to vote on the plan. It is anticipated that the effective date of the plan will be conditioned upon the provision of exit financing in an amount not to exceed $2.0 million to be raised upon exit from bankruptcy. Any parties wishing to objec...

Israeli scientists show bacteria can plan ahead

...ted this type of adaptive anticipation, known as a conditioned response, in dogs in the 1890s. He trained the dog... Pilpel, 'evolution over many generations replaces conditioned learning, but the end result is similar.' 'In both...whether the microorganisms were truly exhibiting a conditioned response, Pilpel and Mitchell devised a further te...

Johnson & Johnson Announces Regulatory Clearance for Its Planned Acquisition of Cougar Biotechnology

...nge Commission (SEC). Termination of the waiting period satisfies one of the conditions to the tender offer. The closing of the tender offer also is conditioned on the tender of a majority of the outstanding shares of Cougar Biotechnology's common stock and the satisfaction of other customary closing condition...

Johnson & Johnson Begins Tender Offer to Acquire Cougar Biotechnology

...cable rules and regulations of the SEC. The closing of the tender offer is conditioned on the tender of a majority of the outstanding shares of Cougar Biotechnology's common stock on a fully diluted basis. The closing is also conditioned on clearance under the Hart-Scott-Rodino Antitrust Improvements Act and oth...

Cell Therapeutics Amends and Restates Its 'Modified Dutch Auction' Tender Offer to a Fixed Price Tender Offer for Any and All of Its $118.9 Million Outstanding Convertible Notes

...change Offers. As of June 1, 2009, approximately $118.9 million aggregate principal amount of the Notes was outstanding. The Exchange Offers are conditioned upon the satisfaction of certain terms and conditions described in the Company's Amended and Restated Offer to Exchange, dated June 2, 2009, the relat...

Johnson & Johnson Announces Definitive Agreement to Acquire Cougar Biotechnology, Inc.

...anding shares of Cougar Biotechnology at $43 per share. The tender offer is conditioned on the tender of a majority of the outstanding shares of Cougar Biotechnology's common stock. The closing is conditioned on clearance under the Hart-Scott-Rodino Antitrust Improvements Act and oth...

MedClean Technologies, Inc. Announces Private Offer to Exchange Warrants

...ms and conditions of the offer to exchange are set forth in the confidential offering memorandum and related letter of transmittal. The offers are not conditioned on a minimum number of Existing Warrants being tendered. However, the offers are subject to certain other conditions, as more fully described in the c...

Cell Therapeutics Amends 'Modified Dutch Auction' Tender Offer for up to $89.2 million of Its Outstanding Convertible Notes

...nder such Notes. As of May 18, 2009, approximately $118.9 million aggregate principal amount of the Notes was outstanding. The Exchange Offer is conditioned upon a minimum of $83,260,100 aggregate principal amount of Notes being validly tendered and not withdrawn, as well as certain other terms and conditi...

Cell Therapeutics to Exchange up to $89.2 million of Its Outstanding Convertible Notes in a 'Modified Dutch Auction' Tender Offer

...ill exchange up to an aggregate of $89.2 million principal amount of Notes representing 75% of the currently outstanding Notes. The Exchange Offer is conditioned on a minimum of $83.2 million aggregate principal amount of Notes being validly tendered and not withdrawn. For each $1,000 principal amount of Notes...

White Paper Shows How to LEED the Way With Green Design

...care rooms and operating rooms; the intensive energy consumption demanded throughout the facility by imaging equipment, medical equipment cooling, and conditioned spaces; issues relating to infection control, including specialized protocols for immunocompromised patients; the need for redundant energy supplies; ...

Conditioned in Biological Products

Pokeweed Mitogen Spleen Cell Conditioned Medium, 25 mL from StemCell Technologies, Inc.

Description: Source of colony stimulating factors for assays of mouse hematopoietic progenitors from bone marrow, spleen, blood and fetal liver. Suitable for the growth of mouse BFU-E, CFU-M, CFU-G and CFU-GEMM when added to methylcellulose at a final concentration of 2-5%, with addition of erythropoietin. Wi...
Company:StemCell Technologies, Inc.

Conditioned in Biological Dictionary

Extinction

...onger presented. In classical conditioning, this refers to the decline of a conditioned response when a conditioned stimulus repeatedly... Examines the theory that we are currently livin...