Conditional

XTENT, Inc. Receives Conditional Approval for Investigational Device Exemption of Custom NX(R) Drug Eluting Stent System from United States Food and Drug Administration

MENLO PARK, Calif., June 4 /PRNewswire-FirstCall/ -- XTENT, Inc. (Nasdaq: XTNT ) today announced that the Company received conditional approval from the United States Food and Drug Administration (FDA) for an Investigational Device Exemption (IDE) authorizing it to begin its pivotal clinical pro...

HeartWare Receives Conditional Approval of IDE

FRAMINGHAM, Mass. and SYDNEY, Australia, May 5 /PRNewswire/ -- HeartWare Limited (ASX: HTW) today announced that it had received conditional approval from the United States Food and Drug Administration (FDA) of an Investigational Device Exemption (IDE) for its lead product, the HeartWare(R) Le...

USDA Agrees to Grant Conditional License to Bioniche for its E. coli O157:H7 Cattle Vaccine

BELLEVILLE, ON, Feb. 5 /PRNewswire-FirstCall/ - Bioniche Life Sciences Inc. (TSX: BNC), a research-based, technology-driven Canadian biopharmaceutical company, today received notice from the United States Department of Agriculture (USDA) that the latest data for its E. coli O157:H7 cattle vacc...

Response Biomedical Corporation Receives Conditional Listing Approval from the Toronto Stock Exchange

VANCOUVER, Nov. 6 /PRNewswire-FirstCall/ - Response Biomedical Corporation (TSX-V: RBM, OTCBB: RPBIF) is pleased to announce that the Toronto Stock Exchange (TSX) has conditionally approved the Company's application for listing its common shares on the TSX. Listing on the TSX will be subject t...

Prozac Gets Conditional Clearance For Treating Children

Prozac has been cleared for treating children over eight years suffering from depression, but regulators have imposed strict conditions on its use//. The conditions imposed by the European licensing agency (EMEA) call for the use of the drug only when other therapies have failed. "Prozac shou...

CryoLife Receives CE Mark Approval for BioFoam(R) Hemostatic Technology

... for the development of products containing a protein hydrogel, which is the primary component of BioFoam." In December 2008, CryoLife received conditional approval from the FDA to conduct the feasibility phase of the company's BioFoam IDE submission for liver parenchymal sealing. The feasibility phase w...

Forterus Inc. Elects Jeff Walton, Former Bear Stearns President, to Board of Directors; Applying to Open New Facility near Los Angeles

...l contacts to assist Forterus in raising capital," said Paul Howarth, CEO. Mr. Howarth said also the Company has submitted an application for a conditional use permit to Ventura County, California, a suburb of Los Angeles, to open a self-contained rehabilitation facility there. "This is a top priority fo...

SOWSIA's Inpatient EHR Solution Gets '08 CCHIT Certification

... SAN FRANCISCO, July 22 /PRNewswire/ -- SOWSIA Healthcare Solutions Inc.'s product Ondemand Healthcare uHPM, 7Plus, M1 is now a pre-market conditional CCHIT Certified(R) 08 Inpatient EHR. The Certification Commission for Health Information Technology (CCHIT(R)) made this announcement today. ...

Prevent Disaster with New Low Cost Temperature Scan Wireless Monitoring System

...tup different reading configurations for each sensor, allowing the ultimate flexibility and customization. Customized alerting capabilities allow for conditional alerts to be sent via email, pager and a number of other possibilities. There are no hidden or monthly recurring fees and the system is modular al...

Econiche(TM) Vaccine Efficacy Summarized in July Issue of Foodborne Pathogens and Disease

...for unrestricted use by Canadian cattle producers and their veterinarians. The United States Department of Agriculture (USDA) cleared the path for a conditional license for the vaccine in February, 2008, and the Company is in the process of completing the required manufacturing steps in the U.S. at this time. ...

Conditional in Medical Technology

DuraHeart(TM) LVAS Receives Conditional Approval for US Pivotal Trial

ANN ARBOR, Mich., March 3 /PRNewswire/ -- Terumo Heart, Inc. announced today that they have received conditional approval from the Food and Drug Administration (FDA) to begin enrollment in the US Pivotal Trial of the DuraHeart (TM) LVAS for a Bridge-to-Transplant (BTT) indication. (Logo: ht...

Arbios Receives Conditional Approval from the FDA to Initiate Pivotal Clinical Trial for SEPET(TM)

Primary Endpoint of the Trial to Be Clarified with FDA WALTHAM, Mass., Feb. 22 /PRNewswire-FirstCall/ -- Arbios Systems, Inc. (OTC Bulletin Board: ABOS) announced today that the Company has received conditional approval from the U.S. Food and Drug Administration ("FDA") of an Investig...

Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

...ctibix has not shown a treatment benefit for patients whose tumors had KRAS mutations in codon 12 or 13. In December 2007, the EMEA granted a conditional marketing authorization for Vectibix as monotherapy for the treatment of patients with EGFR-expressing mCRC with wild-type KRAS genes after failure ...

Studies Examine Quality of Care for Hospitalized Sickle Cell Disease Patients and Effective Methods for Detecting Risk of Stroke in Children With This Disorder

...flow velocity of less than 170 cm/s in the internal carotid and middle cerebral arteries), repeat screening every three to six months in children with conditional TCD results (between 170 and 199 cm/s), and every one to four weeks in children with abnormal TCD results (greater than or equal to 200 cm/s). Transfu...

Berlin Heart's EXCOR(R) Pediatric Receives Unconditional Investigational Device Exemption (IDE) Approval

...The U.S Food and Drug Administration (FDA) has fully approved the Investigational Plan for the IDE study of the device. In 2007, the FDA had granted conditional approval for the prospective IDE study to begin initially at 10 centres with 10 patients, while the company addressed some questions the FDA had found...

Sunshine Heart Announces IDE Approval To Begin C-Pulse U.S. Clinical Feasibility Trial

...e/ -- Sunshine Heart (ASX: SHC), a global medical device company focused on innovative heart assist technologies, today announced that it has received conditional approval of an Investigational Device Exemption (IDE) from the U.S. Food and Drug Administration (FDA) to begin its first U.S. clinical feasibility tr...

Clinical Proof of Concept for TGF-beta 2-Inhibitor AP 12009 in Phase Iib EMEA provides Guidance on Phase III Design and Approval Requirements

...ts. Furthermore, 14-month progression rate was accepted as the endpoint for conditional approval. The drug designed for the targeted treatment of recurrent or re...onths as the surrogate endpoint. Positive results will allow submission for conditional approval by the EMEA. The SAWP at the EMEA indicated that, due to the rarit...

PLC Systems Announces Approval of First European Study to Evaluate RenalGuard(TM)

...positive safety data collected in the pilot study and discussions with FDA, PLC stopped enrolling new patients in the pilot study and has received FDA conditional approval to commence a U.S. pivotal trial to study the effectiveness of its RenalGuard in the prevention of CIN. Contrast-Induced Nephropathy Appr...

FDA Approves HIFU Clinical Trial for Recurrent Prostate Cancer

...D, Fla., May 13 /PRNewswire/ -- USHIFU, LLC, the clinical trial management provider for Focus Surgery, Inc. (Indianapolis, IN), is pleased to announce conditional written approval pending minor changes to the protocol from the FDA to begin a pivotal trial for the treatment of recurrent prostate cancer with the S...

Arbios Receives Approval From the FDA to Initiate Pivotal Trial for SEPET(TM) Liver Assist Device

...pleased to have received FDA approval to start the SEPET pivotal trial and to have fully satisfied the points addressed in the FDA's previously issued conditional approval," commented CEO and President Shawn Cain. "We were pleased with the compelling results from the SEPET feasibility trial, and we are excited t...

Conditional in Biological News

Telomeres resemble DNA fragile sites

...he discovery is a protein known as TRF1, which de Lange, in an effort to understand how telomeres protect chromosome ends, discovered in 1995. Using a conditional mouse knockout, de Lange and Sfeir have now revealed that TRF1, which is part of a six-protein complex called shelterin, enables DNA replication to dr...

K-State researchers help Epitopix license the United States' first E. coli O157 vaccine for cattle

...exas A&M University. "We're excited that this vaccine has been granted a conditional approval by the U.S. Department of Agriculture," Thomson said. "We have bee... a research collaborator for Epitopix to conduct the work that lead to this conditional approval. Epitopix will now be able to offer this pre-harvest food safety t...

Forest inventories in California include more than trees

... average annually between 2001 and 2005. Modeling crown fire potential under extreme weather conditions showed that fire would occur as a surface or conditional surface fire in 72 percent of forests, and as a passive crown fire in only 20 percent of forests. In most cases, fuel treatment may require only th...

October 2008 Biology of Reproduction highlights

...activity to determine the developmental role of DICER by whole-organism and conditional gene disruptions. In a paper on p. 696 of this issue, Maatouk et al. add im...1 is required for normal spermatogenesis in the mouse. These authors used a conditional knockout (CKO) approach to delete Dicer1 in the germline. Because the CKO...

Sociological research shows combined impact of genetics, social factors on delinquency

...n behavioral motivation, aggression, emotion and cognition (e.g., serotonin, dopamine, norepinephrine). Among the findings, the research suggests a conditional interaction between repeating a school grade and the MAOA*2 repeat (2R) allele in adolescent boys. For those who did not have the 2R allele, repeating...

It is important to demonstrate the influence of the microenvironment in the process of metastasis

... it was aimed at identifying the origin of the factors regulating the expression of those genes. An in vitro model based on crops in the presence of conditional media The in vitro model developed in this PhD thesis differs from current models in which the cell line from the human colon cancer is cultured i...

Cell response to stress signals predicts tumors in women with common pre-breast cancer

...of breast cancer, which was a striking discovery, according to Tlsty. We found that the expression of biomarkers of a stress-associated response is conditional and can reflect two distinct processes distinguished by the absence or presence of a proliferation of cells, added Tlsty. We anticipate that these ph...

'Smart' mice teach scientists about learning process, brain disorders

... being able to "knock out" the gene for Cdk5 only in the brain, and only when the mice were adults. This technique, only recently developed and called conditional knockout, allows much more sophisticated experiments than traditional knockout, which entirely eliminates the gene. "Being able to turn a gene of...

Spelling out cancer on the nanoscale

... In previous work, the Felsher group had shown that inactivating MYC induces sustained tumor regression in mice. The researchers decided to test their conditional model of MYC-induced lymphoma by using their nano-fluidic system to quickly measure the impact of targeted protein inhibitors in mice. A series of fin...

How the US drug safety system should be changed

...poses an alternative approach with three elements: conditional approval, an empowered US Food and Drug Administra...ally approved, it should ideally enter a period of conditional approval, he says. In this period, marketing, espe...d to be clearly marked that the drug's approval is conditional and has only been studied in a limited number of p...

Conditional in Biological Technology

Schering-Plough Reports Financial Results for 2009 Second Quarter

...agent for use in heart bypass surgery; and In Animal Health, the launch of the first vaccine against canine influenza virus, which was granted a conditional product license by the U.S. Department of Agriculture (USDA) in May. Regarding the planned merger with Merck announced on March 9, ...

Inverness Medical Innovations - Concateno plc, Further Announcement Regarding UK Takeover Code Share Dealing Disclosure Requirements.

...bsite at http://www.thetakeoverpanel.org.uk . "Interests in securities" arise, in summary, when a person has long economic exposure, whether conditional or absolute, to changes in the price of securities. In particular, a person will be treated as having an "interest" by virtue of the ownership or con...

Clavis Pharma Raises NOK 129 Million (USD 20 Million) in a Private Placement to Fund Further Development of its Pipeline of Novel Anticancer Drug Candidates

...gotiate appropriate partnership agreements as well as for general corporate purposes Completion of the Private Placement is conditional upon approval by the Company's Extraordinary General Meeting to be held on or about 15 July 2009 (the "EGM"). Shareholders representing more than the ...

Beckman Coulter, Inc. Announces Pricing of Common Stock Offering

...pect," "anticipate," "intend," "estimate," "may increase," "may fluctuate," "plan," "goal," "target," "strategy," and similar expressions or future or conditional verbs such as "may," "will," "should," "would," and "could." These statements are based on current expectations, forecasts and assumptions and are su...

Beckman Coulter Prices $500 Million Senior Notes Offering

...pect," "anticipate," "intend," "estimate," "may increase," "may fluctuate," "plan," "goal," "target," "strategy," and similar expressions or future or conditional verbs such as "may," "will," "should," "would," and "could." These statements are based on current expectations, forecasts and assumptions and are su...

GlaxoSmithKline and Stiefel to Create New World-Leading Specialist Dermatology Business

...s than 1%) and to be 1-2% accretive to EPS in 2010. The transaction has been approved by the Stiefel stockholders. Closing of the transaction is conditional upon certain matters including receiving certain regulatory clearances and no material adverse change occurring in respect of Stiefel's business prior...

Pharmexa and Affitech to Combine Operations to Create a New Antibody Therapeutics Company

... COPENHAGEN and OSLO, March 4 /PRNewswire/ -- Pharmexa A/S and Affitech AS announced today that they have entered into a conditional agreement to merge the two companies by means of a share for share acquisition by Pharmexa A/S of the private Norwegian company, Affitech AS. The purp...

Cytopia Letter to Progen Shareholders

...ing form is attached. The share buy-back resolution (Resolution 3) is conditional on the merger resolution (Resolution 1) being passed, and in any case, limi...es in 2009. Website: www.cytopia.com.au Notes Resolution 3 is conditional on Resolution 1 being passed, and in any case, limits the share buy-back to...

Insmed Sells Follow-on Biologics Platform to Merck & Co., Inc. for Gross Proceeds of $130 Million

... approximately $1.2 million per month. This transaction, in accordance with Virginia corporate law, does not require a shareholder vote, though it is conditional on certain closing requirements, including obtaining necessary consents. RBC Capital Markets served as exclusive financial advisor to Insmed on...

Cytopia and Other Progen Shareholders Maintain Call for Meeting

...have been put forward to Progen by shareholders, no merger resolution has been proposed, nor are the appointments of the three new director candidates conditional on a merger going forward. These directors seek appointment on a declared platform of considering a merger between Cytopia and Progen but such a merge...

Conditional in Biological Products

* Quick & Easy Conditional Knock Out Kit - FRT from Gene Bridges GmbH

Description: This kit is designed for the fast and simple integration of FRT-sites into large vector plasmids at any position (for the generation of transgenic mouse models). The included FRT-PGK-gb2-neo-FRT cassette is designed to allow neomycin / kanamycin selection in prokaryotic and eukaryotic cells. It com...
Company:Gene Bridges GmbH

* Quick & Easy Conditional Knock Out Kit - loxP from Gene Bridges GmbH

Description: This kit is designed for the fast and simple integration of loxP-sites into large vector plasmids at any position (for the generation of transgenic mouse models). The included loxP-PGK-gb2-neo-loxP cassette is designed to allow neomycin / kanamycin selection in prokaryotic and eukaryotic cells. It ...
Company:Gene Bridges GmbH

EZChrom Elite from JASCO

Description:...m is its built-in automation features and strong control of the dataacquisition process. It takes advantage of the latest tools in automation to allow conditional actions to be preprogrammed as part of the dataacquisition. GLP/GMP Features Users in regulated environme...
Company:JASCO

Conditional in Biological Dictionary

Site-specific recombination

...cific recombination reactions on cer, psi and dif. ... The directional character of site - specific recombination is controlled by the ... conditional site - specific recombination in mammalian cells using a ligand ... Transgene Management Through Site - Specific Recombination (410641)Ob...

Probability

...A can occur divided by ... Probability concepts are presented in this unit by Math Goodies. ... experiments, outcomes, sample spaces, events, and conditional probability . ... An introduction to probability . ... Introduction to Probability ... For example, if the probability of picking a red marbl...

Gene targeting

...e ... Gene targeting is the process of disrupting or mutating a specific genetic locus ... Caliper Life Sciences: The creation of standard or conditional knockout mice, or knockin mice, utilizes some proprietary gene targeting methodologies developed in ... Gene targeting - old and new ... Ca...

Disjunction

... connective which ... The connective "or" in English is quite different from disjunction . ... Writings by Avi Sion: FUTURE LOGIC, Categorical and conditional deduction and induction of the natural, temporal, extensional and logical modalities Exclusive disjunction is the sense of the word or as in th...