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Concomitant in Medical News

Clinical trial data: Safety/efficacy of concomitant formoterol fumarate/tiotropium treating COPD

Napa, CA (October 24, 2007) Data presented today at CHEST 2007, the annual scientific assembly of the American College of Chest Physicians (ACCP), demonstrate concomitant use of nebulized formoterol fumarate and tiotropium provided improved bronchodilation over tiotropium monotherapy and was well...

FDA Approves LIVALO(R) for Primary Hypercholesterolemia and Combined Dyslipidemia

...therapy for a broad range of patients including the elderly, patients with diabetes and those whose treatment is complicated by concurrent disease and concomitant medications. About Dyslipidemia and Hypercholesterolemia Dyslipidemia refers to abnormal levels of fatty substances in the blood, o...

INVEGA(R) Approved as the First and Only Treatment for Schizoaffective Disorder

... mg with the option to reduce to 3 mg, or 12 mg with the option to reduce to 9 mg. In addition to study medication, subjects were permitted to receive concomitant treatment with a mood stabilizer and/or antidepressant, provided these medications had been given at a stable dose within 30 days of screening. Approx...

FDA Approves TYVASO (Treprostinil) Inhalation Solution for the Treatment of Pulmonary Arterial Hypertension

...sure, TYVASO may cause symptomatic hypotension. TYVASO may also increase the risk of bleeding, particularly in patients receiving anticoagulants. The concomitant use of TYVASO with diuretics, antihypertensives or other vasodilators may increase the risk of systemic hypotension. Hepatic or renal insufficiency m...

MULTAQ(R) (dronedarone) for Atrial Fibrillation or Atrial Flutter Now Available in the United States

...ation has a rapid onset, reaches a plateau after 7 days and is reversible after discontinuation. Hypokalemia and hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. Potassium levels should be maintained in the normal range pre and during administration. For...

Radiology Informatics: Frost & Sullivan Examines the Next Big Wave in Medicine

...lities. Its aim is to assist radiologists in arriving at a quicker interpretation and also contribute towards recommending other necessary actions for concomitant requirements. Reporting errors, wrong interpretations, and patient report delays due to an unavailability of radiologists will eventually be eliminate...

FDA Approves Multaq(R) for Patients with Atrial Fibrillation or Atrial Flutter

...evation has a rapid onset, reaches a plateau after 7 days and is reversible after discontinuation. Hypokalemia and hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. Potassium levels should be maintained in the normal range pre and during administration. For f...

Novo Nordisk Insulin Analogs Have Proven Safety Profiles

...eed to be adjusted in patients with renal or hepatic impairment. Levemir(R) should not be diluted or mixed with any other insulin preparations. concomitant oral antidiabetes treatment may require adjustment. Levemir(R) is not to be used in insulin infusion pumps. Inadequate dosing or discontinuation of...

NUCYNTA(TM) (tapentadol) CII Immediate Release Tablets Now Available for Relief of Moderate to Severe Acute Pain

... The development of a potentially life-threatening serotonin syndrome may occur with use of SNRI products, including NUCYNTA,(TM) particularly with concomitant use of serotonergic drugs such as SSRIs, SNRIs, TCAs, MAOIs and triptans, and with drugs which impair metabolism of serotonin (including MAOIs). Sero...

Health Care Reform May Force U.S. Pharmaceutical Companies to Overhaul Sales Strategies, Says New Report From ZS Associates and eyeforpharma

...ir influence over physician prescription decisions in the United States. So even if a pharmaceutical company fails to obtain a favored spot -- and the concomitant smaller co-pay -- for its drug on a payer's formulary in the United States, physicians and patients still can opt for the drug. This contrasts wi...
Concomitant in Medical Technology

Clinical Trial Data on the Safety and Efficacy of Concomitant Formoterol Fumarate/ Tiotropium Treatment for COPD

-Data from Phase IIIb clinical study presented at CHEST 2007 on concomitant use of Perforomist(TM) Inhalation Solution with tiotropium for COPD treatment- NAPA, Calif., Oct. 24 /PRNewswire-FirstCall/ -- Data presented today at CHEST 2007, the annual scientific asse...

Study Demonstrates Efficacy of Pitavastatin in Elderly Patients

...ry hypercholesterolemia or combined dyslipidemia. About half of the patients had hypertension, 5 percent had diabetes and about 80 percent were taking concomitant medications. A 60-week, open-label extension to this core study was conducted to assess the long-term safety of pitavastatin at the recommended starti...

Cardiogenesis Announces Presentation of its PHOENIX(R) Combination TMR Plus Stem Cell Delivery System at the International Society of Minimally Invasive Cardiothoracic Surgeons (ISMICS) Annual Meeting

...ascularized by conventional methods. Eight patients treated with the PHOENIX System completed 1 year follow up: Seven patients had concomitant coronary bypass grafting, one patient stand alone therapy. There was no operative or hospital mortality. One year survival was 100%. C...

Neurobiological Technologies' Partner, Celtic Pharma, Announces Results of XERECEPT(R) Phase 3 Clinical Program

...cal studies demonstrating potential anti-tumor and angiogenesis inhibition effects of XERECEPT(R). "The ability to reduce the use of steroids and concomitant reduction in adverse side effects in the treatment of patients with brain tumors is an important goal," said Lawrence Recht, MD, Professor of Neurolog...

Bayer Announces Leukine(R) Data Presentations at 45th American Society of Clinical Oncology (ASCO) Annual Meeting

...arrow or peripheral blood (10 percent), in patients with known hypersensitivity to GM-CSF, yeast derived products or any component of Leukine, and for concomitant use with chemotherapy and radiotherapy. Serious allergic or anaphylactic reactions have been reported with Leukine. If any serious or anaphylactic r...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

...urred upon rechallenge. Several postmarketing reports describe patients able to tolerate the reintroduction of Gleevec at a lower dose with or without concomitant corticosteroids or antihistamines following resolution or improvement of the bullous reaction. Consider potential toxicities-specifically liver, ...

Video: UCB Launches Vimpat(R) in the U.S. for Add-On Treatment of Epilepsy in Adults

...at(R) demonstrated efficacy and tolerability when combined with a broad range of existing AEDs, and also provided efficacy regardless of the number of concomitant AEDs. Vimpat was also studied with several commonly used medications, including digoxin, metformin, omeprazole, and an oral contraceptive (containing ...

New Phase 3 Study of Tapentadol Immediate Release Tablets Published in Current Medical Research and Opinion Journal

... The development of a potentially life-threatening serotonin syndrome may occur with use of SNRI products, including NUCYNTA(TM), particularly with concomitant use of serotonergic drugs such as SSRIs, SNRIs, TCAs, MAOIs and triptans, and with drugs which impair metabolism of serotonin (including MAOIs). Sero...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

... antipsychotic drugs and other drugs not essential to concurrent therapy, intensive symptomatic treatment and medical monitoring, and treatment of any concomitant serious medical problems. Tardive Dyskinesia (TD): TD is a syndrome of potentially irreversible, involuntary, dyskinetic movements that may dev...

U.S. Naval Medical Research Center Proposed 'RESUS' Clinical Trial in Trauma Patients Remains on FDA Hold

...RESUS or OP RESUS to proceed in the foreseeable future. The company expects the NMRC to seek FDA approval for a clinical trial of Hemopure with a concomitant drug to address vasoactivity, which occurs with the use of Hemopure alone. The NMRC and the FDA are in discussions concerning such a trial, and the N...
Concomitant in Medical Products

Renin IRMA Test

Description:...ion. In addition, angiotensin II stimulates aldosterone secretion from the adrenal gland, resulting in increased renal tubular sodium reabsorption and concomitant secretion of potassium and hydrogen [1]. Renin plasma levels are useful in the diagnosis of hypertension. Plasma renin is reduced in patients with hyp...
Company:Diagnostic Systems Laboratories, Inc.

Contigen Bard Collagen Implant

Description:...oft network of fibers, inducing new tissue growth at the injection site. Contigen Bard Collagen Implant is used successfully as stand-alone therapy or concomitant therapy supporting surgical sling or pelvic reconstructive repairs....
Company:Bard Urological Division

In-Fast™ Ultra Transvaginal Sling

Description:... The In-Fast™ Ultra Sling is a minimally invasive treatment for female stress urinary incontinence. A concomitant repair surgery can be performed at the same time. This approach avoids an abdominal incision.To place a sling, the In-Fast Ultra inserter is used to d...
Company:AMS

Strange Endoscopic Cholangiography Catheter

Description:... Used for cholangiography and bile stone removal using fluoroscopy. Dual lumen catheter design allows concomitant fluoroscopic biliary imaging and wire basket placement for stone extraction. Supplied sterile in peel-open packages. Intended for one-time use....
Company:Cook Surgical

Strange Cholangiography Set: With N-Circle® Nitinol Tipless Stone Extractor

Description:... Used for cholangiography and bile stone removal using fluoroscopy. Dual lumen catheter design allows concomitant fluoroscopic biliary imaging and wire basket placement for stone extraction. Supplied sterile in peel-open packages. Intended for one-time use....
Company:Cook Surgical
Concomitant in Medical Definition

Body shaping

...y leaves long, visible scars on the arms, chest, stomach and legs . Nonetheless, the body lifting procedure is growing in popularity , thanks to a concomitant rise in weight loss surgeries on the stomach. For instance, in the year 2000 , 207 lower body lifts took place, according to the American Society of ...
Concomitant in Medical Dictionary

Concomitant

The designation concomitant drugs has two contextual uses: as used in medicine or as used in drug abuse. Dictionary.com - Largest free online dictionary and audio pronunciation. ... Popular Daily Crossword Crossword Solver Full Text Translator Toolbar Word Games ... Definition of conco...

Speech impairment

...ype of speech impairment . ... More about Speech Disorders: Causes and symptoms Diagnosis Treatment Alternative ... They may occur without a concomitant impairment of speech production. ... Speech Impairments / Hearing Impairments -- Definitions / Disorders of the Outer ... SPEECH IMP...

Intramuscular

...des. intramuscularly. intramuscularly. intramuscularly ... Find information on prescribing ZYPREXA® IntraMuscular (olanzapine for injection) ... concomitant administration of intramuscular olanzapine and parenteral ... progesterone- intramuscular glossary includes a list of progesterone- intramusc...
Concomitant in Biological News

Early initiation of Arctic sea-ice formation

...to the atmosphere and increased the amount of solar radiation reflected back out into space. "A stable sea-ice regime also suggests the possibility of concomitant glacial ice," say the researchers, and indeed they find some evidence for the presence of small isolated glaciers at the time. Furthermore, their d...

Fire is important part of global climate change, report scientists

...hors report. "The tragic fires in Victoria, Australia, emphasize the ubiquity of recent large wildfires and potentially changing fire regimes that are concomitant with anthropogenic climate change," said first author David Bowman, professor at the University of Tasmania. "Our review is both timely and of great r...

Protein structure determined in living cells

... Gntert. "Unfortunately, the cells survive for only a 5-6 hours without supply of oxygen and nutrients. Gntert and his colleagues compensated for the concomitant drastic reduction of the measurement time by computational reconstruction of the complete spectrum. Then, they calculated a detailed three-dimensional...

Gene therapy reversed heart damage in heart failure

...yme with ARKct was sufficient to reverse heart failure even without concomitant metoprolol. The rats that received GFP or saline alone experienced more ... of the study. This deterioration was prevented, but not reversed, with the concomitant metoprolol. "Our data show that beta blockers and the ARKct pept...

Organic plant waste proves effective weed control for citrus trees

...used effectively for controlling weeds in citrus groves. Their effectiveness in controlling weeds may increase their use in agriculture systems with a concomitant decrease in the need for synthetic herbicides. Further studies are needed to evaluate their side effects on beneficial organisms, diseases, and insect...

New cardiology research presented at CHEST 2008

... therapy for patients with pulmonary arterial hypertension (PAH). Italian researchers randomized 405 patients with PAH, of whom 53 percent were taking concomitant bosentan, to two study arms. The groups received either tadalafil or placebo orally once daily as monotherapy or as add-on therapy to bosentan. Compar...

Cow power could generate electricity for millions

...t attempt to outline a procedure for quantifying the national amount of renewable energy that herds of cattle and other livestock can generate and the concomitant GHG emission reductions. Livestock manure, left to decompose naturally, emits two particularly potent GHGs nitrous oxide and methane. According t...

Mitochondrial dysfunction and redox signaling in atrial tachyarrhythmia

...thway activation, led us to conclude that the elevated frequency per se and concomitant Ca2+-overload precede and induce mitochondrial dysfunction and oxidative st...and cellular effects that are solely due to the AF excluding the effects of concomitant cardiac diseases. Dr. Steven R. Goodman, Editor-in-Chief of Experimental ...

Influenza vaccine causes weaker immune response for children of rural Gabon than in semi-urban areas

...children than in their semi-urban counterparts, likely because of co-infection with parasites and/or poor nutrition. Closer attention to nutrition and concomitant infections may profoundly affect responses to pandemic influenza and influenza vaccines in developing countries. With the current attention to the...

Protein may hold key to decreasing organ dysfunction rates in heart transplants

... involvement in the systemic response to IR. "The major goal of our research activities is therefore to understand the exact mechanisms of this injury concomitant to organ transplantation," notes Aigner, stressing the value of this research to the development of new treatment options in organ transplantation. ...
Concomitant in Biological Technology

EnVivo Pharmaceuticals Announces Reversal of Cognitive Deficits in Alzheimer's Disease Transgenic Mouse Model With Gamma-Secretase Modulator

...hese findings since they represent to us the first demonstration with a bona fide GSM of functional improvement in an Alzheimer's disease model with concomitant lowering of AB42," said Kees Been, president & CEO of EnVivo. "We have also described the acute AB42 lowering effects of EVP-0962 in brains of non...

Phase 3 Cystic Fibrosis Trial Results Presented at European Conference

...ed an immediate and sustained improvement in lung function (FEV1) over the 26 weeks (p<0.001). -- For the subgroup of patients on concomitant rhDNase there was also a significant improvement in FEV1 from baseline (88mL) and from placebo (109mL) at week 26 with Bronchitol (p=0.0...

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

...atients who developed these infections were taking concomitant immunosuppressants such as methotrexate or cortico...atients taking CIMZIA 200 mg every other week with concomitant methotrexate (n=640) and more frequently than with placebo with concomitant methotrexate (n=324) were upper respiratory tract ...

HHS Awards MedImmune Contract to Manufacture Live Attenuated Nasal Spray Vaccine for Novel Influenza A (H1N1)

...ins, gentamicin, gelatin or arginine or with life- threatening reactions to previous influenza vaccinations, and in children and adolescents receiving concomitant aspirin or aspirin-containing therapy. Do not administer FluMist to children less than two years of age due to an increased risk of hospitalizati...

NIMOTUZUMAB DEMONSTRATES EFFICACY IN RANDOMIZED HEAD & NECK CANCER STUDY WITHOUT THE TOXICITIES ASSOCIATED WITH OTHER EGFR DRUGS

... squamous cell head and neck cancer. J Clin Oncol 21:92-98, 2003); (Calais G, Alfonsi M, Bardet E, et al: Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced stage oropharynx carcinoma. J Natl Cancer Inst 91:2081-2086, 1999). "The data from the Reddy BK et a...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...o- and thrombovascular events, use the lowest dose needed to avoid red blood cell transfusion. Use ESAs only for treatment of anemia due to concomitant myelosuppressive chemotherapy. ESAs are not indicated for patients receiving myelosuppressive therapy when the anticipated outcome is cure....

ChartTrends(R): Bone and Mineral Metabolism in Dialysis Reveals Latest Trends in the Treatment of Calcium, Phosphorus and PTH

...formulations such as Abbott's Zemplar and Genzyme's Hectorol. The use of Nutritional Vitamin D (i.e. ergocalciferol) appears to be increasing and the concomitant use of Nutritional Vitamin D does have an impact on the dose of Active Vitamin D. Although the use of Active Vitamin D is widespread, a substantial n...

Latest BioTrends Research Reports to Assess the Impact of the Withdrawal of Raptiva (efalizumab) on the Psoriasis Market

...se of biologic agents, patient demographics/co-morbidities associated with specific biologic brand use, product switching incidence and rationale, and concomitant medications. A special section focused on switches from Raptiva will be included to understand if these patients migrate to other biologic brands or ...

Medivation Announces New Positive Efficacy Data From Phase 1-2 Trial of MDV3100 in Castration-Resistant Prostate Cancer Patients

...reported adverse event was fatigue. Two witnessed seizures occurred in patients taking doses of 600 mg/day and 360 mg/day. Both patients were taking concomitant medications that can cause seizures. A possible but unwitnessed seizure was reported in a patient taking a dose of 480 mg/day. "We are pleased ...

FDA Approves KAPIDEX(TM) (Dexlansoprazole) delayed release capsules for the Treatment of GERD

...bsorption of drugs for which gastric pH is important for bioavailability (e.g., ampicillin esters, digoxin, iron salts, ketoconazole). Patients taking concomitant warfarin may require monitoring for increases in international normalized ratio (INR) and prothrombin time. Please see the complete prescribing i...
Concomitant in Biological Definition

Diabetes mellitus

...above 300 mg/dl) water will be osmotically driven out of cells into the blood. The kidneys will also be "dumping" glucose into the urine, resulting in concomitant loss of water, causing an increase in blood osmolality . The osmotic effect of high glucose levels combined with the loss of water will eventually re...

Hepatitis B

... to generate the genomic DNA to deliver to its progeny. Additionally, the DNA genome is incomplete on one strand. Hepatitis D infection requires a concomitant infection with hepatitis B. Co-infection with Hepatitis D increases the risk of liver cirrhosis and subsequently, liver cancer. Hepatitis B infectio...
Concomitant in Biological Dictionary

Supergene

...upergene processes or enrichment occur relatively near the surface. Supergene processes include the predominance of meteoric water circulation with concomitant oxidation and chemical weathering. The descending meteoric waters oxidize the primary (hypogene) sulfide ore minerals and redistribute the metalli...

Polyadenylation

...tion in activating c-mos mRNA differs from its role ... Cytoplasmic polyadenylation is often correlated with, and can cause, ... This process is concomitant with the polyadenylation of mRNA until the MII stage ... and mouse oocytes, cytoplasmic polyadenylation and sequential translation of ... ...
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