Combination

Combination therapy boosts effectiveness of telomere-directed cancer cell death

Sometimes apotential target for a drug seems very promising on paper; things areoften very different in reality. Its the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe...

DNA Recombination and Repair—A New Twist to RecA Function

Molecular motors harness the energy of ATP (or GTP, a related energy currency) and transform it into mechanical force. Well-known examples of motors include myosin and dynein, proteins that use ATP to ferry intracellular cargo along fibers made of actin or tubulin proteins. The ATP-dependent assembly of actin or tubulin fibers itself can work as a motor: for instance, the march of white blood cel...

Wake Forest scientists find new combination vaccine effective against plague

Plague, a bacterium that ravaged Europe in the Middle Ages and is today one of the most feared potential agents of bio-terrorism, may have met its match, according to Wake Forest University School of Medicine scientists. Steven B. Mizel, Ph.D., principal investigator, told the American Gastroenterological Association meeting in Chicago that when mice immunized with a new combination vaccin...

Combination therapy leads to partial recovery from spinal cord injury in rats

Combining partially differentiated stem cells with gene therapy can promote the growth of new "insulation" around nerve fibers in the damaged spinal cords of rats, a new study shows. The treatment, which mimics the activity of two nerve growth factors, also improves the animals' motor function and electrical conduction from the brain to the leg muscles. The finding may eventually lead to new ways...

Study shows combination of immune substances to be safe

New research has shown that the immune-stimulating hormone known as interleukin-12 (IL-12) can safely be administered with interferon, another immune-system protein, as an experimental therapy for some cancers. Normally, interferon is used alone to stimulate the immune system to attack certain cancers. This strategy, a form of immunotherapy, is sometimes used to treat melanoma, advanced k...

More>>

Combination at Biology Products

Affi-Gel 10 to 15 Combination, 2 x 25 ml each from Bio-Rad

Description:Activated affinity media for spontaneous ligand immobilization can be coupled with a ligand such as an antibody, enzyme, antigen, or receptor to create an affinity matrix of choice. Affi-Gel 10 and Affi-Gel 15 supports couple ligands via primary amines. Affi-Gel 10 gel couples neutral or basic proteins with pI from 6.5 to 11; Affi-Gel 15 gel couples acidic proteins with pI less than 6.5. This Aff...
Company:Bio-Rad

Combination Roto Shake Genie from Femto Scientific

Description:...
Company:

Anti-CD45 / CD34 Combination Monoclonal Antibody, FITC, PE Conjugated from BD Biosciences - Immunocytometry Systems

Description:CD45/CD34 combination 50 tests...
Company:BD Biosciences - Immunocytometry Systems

Combination at Biology Technology

Generate Adenovirus Vectors in E. coli by Homologous Recombination with the AdEasy Adenoviral Vector System

Efficient gene transfer and high-level protein expression within a varietyof cells Stratagene Recombinant adenoviruses provide a versatile means of gene delivery andexpression. We describe the AdEasy adenoviral vectorsystem, whichsimp...

The combination of monolithic columns and modern HPLC/MS/MS instrumentation for high chromatographic throughput and sensitive detection of beta-agonists

Beta-agonists are group A substances of the European guideline 93/257/EWG (revision 98/536/EG) having an anabolic effect and not licensed. Thus, they have to be determined in veterinarian samples like muscle, liver, retina, and urine. The coupling of High Pressure Liquid Chromatography (HPLC) and Electrospray Ionization Tandem Mass Spectrometry (ESI-MS-MS) seems to be the analytical m...

Combination at Biology Definition

Recombination

cros...

Genetic recombination

,...

Combination at Biology Dictionary

Site-specific recombination

events are examples of non-<a href="/ ?q=/ Biology-Di...

Recombination nodules

o...

Recombination frequency

The frequency at which <a href="/ ?q=/ Bio...

Recombination

s through the <a href="/ ?q=/ Biology-Dictionary/ ...

Homologous recombination

The e...

More>>

Combination at Medicine News

Consensus on "Combination Therapy" for Breast Cancer

Breast cancer is the commonest cancer among women in the world. There has been some on going controversy on certain aspects of treatment modalities of this cancer. Besides surgery there are other options to treat the cancer including radiation, chemotherapy and hormonal therapy. Now at a three-day conference at the National Institutes of Health doctors have agreed to a consensus on the combinati...

The bad combination

People who drink and smoke have to drink more to feel drunk than non-smoking drinkers – placing them at greater risk of damage to their brains, livers and hearts, a new study suggests. The study shows nicotine substantially reduces blood alcohol levels in rats, which are considered a good model for humans.Since alcohol abusers generally "drink to effect", they will end up drinking mor...

Drug Combinations May Boost Stroke Risk

People who combine different types of serotonin-enhancing medications, such as certain antidepressants and migraine medications, may be increasing their risk of stroke. //The study reports on three patients who developed ischemic strokes related to the use of serotonin-enhancing medications, which include certain antidepressants, anti-migraine drugs, decongestants and diet pills. Ischemic strokes...

Combination therapy to treat breast cancer

The combination of two targeted drug therapies results in dramatic reduction in breast cancer cell growth in vitro, indicating a potentially powerful new approach to treating the condition.// The two drug agents – trastuzumab and ZD1839 were found to work synergistically to inhibit the action of two different growth factors receptors, HER2 and epidermal growth factor receptor (EGFR). P...

Combination regime may work against prostate cancer

A recent study published in the Journal of Clinical Oncology suggests that men with advanced Prostate Cancer respond better to a combination of Vitamin D with the chemotherapy drug// Taxotere. A phase II clinical trial of 35 men treated with a combination of Taxotere and Calcitriol found that this combination regime was more effective than treatment with Taxotere alone. This was measur...

More>>

Combination at Medicine Products

Pediatric Combination Eye Garter Shield Cover and Fox Shield

Description:Includes one aluminum pediatric eye shield and one eye garter shield cover. Packaged 50 per box. White only....
Company:Bausch & Lomb Storz

Combination Eye Garter Shield Cover and Fox Shield

Description:Includes one aluminum Fox eye shield and one eye Garter shield cover. Packaged 50 per box. White only....
Company:Bausch & Lomb Storz

Spanish HRR/Amsler Combination

Description:Spanish HRR/Amsler combination with Spanish and English directions for both HRR and amsler tests plus occluding glasses....
Company:Richmond Products, Inc.

Tango SLT and Photodisruptor Combination Laser

Description:The Laserex Tango ophthalmic laser system provides two lasers in the one system: an SLT laser and a photodisruptor for posterior capsulotomy and iridotomy. The SLT laser is a frequency-doubled Nd:YAG producing pulsed 532 nm light. The photodisruptor laser is an Nd:YAG producing 1064 nm. The appropriate laser can be easily selected and treatment by both lasers is channelled through the same delive...
Company:Ellex (formerly Laserex)

DGH-5100e Combination A-Scan/Pachymeter

Description:Combination A-Scan/Pachymeter with graphic display and IOL power calculation software. All A-scans and A-Scan/Pachymeter combination units include firmware module with SRKII, SRKT, Holladay Dioptimum and Binkhorst II formulas. Audible tones increase in frequency the closer you get to visual axis. Constant tone when alignment is achieved with corneal indentation. Triple tone when measurement is ob...
Company:DGH Technologies, Inc.

More>>

Combination at Medicine Technology

Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkin's Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy

Positive interim results prompt request for meeting with FDA SEATTLE, July 11, 2007 /PRNewswire-FirstCall/ -- CellTherapeutics, Inc. (CTI) announced today that interim results ofits phase II/III trial comparing CPOP-R, in which pixantrone issubstituted for doxorubicin in standard CHOP-R first-line treatmentof patients with aggressive non-Hodgkin's lymphoma (NHL), resultedin essentially al...

New Phase 3 Study Published in The Lancet Evaluates Efficacy and Safety of Prezista/Ritonavir vs. Kaletra as Part of HIV Combination Therapy in Treatment-Experienced Adults With HIV

BRIDGEWATER, N.J., July 05, 2007 /PRNewswire/ -- Results fromthe primary analysis of a randomized, controlled, open-label, Phase3 study showed that 77 percent of treatment-experienced HIV-1infected adults taking PREZISTA(TM) (darunavir) 600 mg tablets with100 mg ritonavir (PREZISTA/r) twice daily, plus an optimizedbackground regimen (OBR) of antiretroviral (ARV) agents, reached aplasma v...

Cyclacel Pharmaceuticals Announces Results of Phase II Seliciclib Combination Studies

BERKELEY HEIGHTS, N.J.--(BUSINESS WIRE)--Jun 28, 2007 - CyclacelPharmaceuticals, Inc. (NASDAQ: CYCC, NASDAQ: CYCCP) announced todaythe results from two Phase II non-randomized studies of seliciclibfixed dose combinations. In one study seliciclib was given incombination with gemcitabine and cisplatin and in another withdocetaxel in patients with advanced non-small cell lung cancer(NSCLC).<p...

An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes

CHICAGO--(BUSINESS WIRE)--Jun 25, 2007 - New data from aninvestigational study released at the American Diabetes Association(ADA) 67th Annual Scientific Sessions showed that initialcombination therapy with Januvia(TM) (sitagliptin) and metformindemonstrated significant improvement in markers of beta cellfunction in patients with type 2 diabetes. Pancreatic islet betacell function determines...

Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes

CHICAGO--(BUSINESS WIRE)--Jun 23, 2007 - Late breaking datapresented at the American Diabetes Association (ADA) 67th AnnualScientific Sessions showed that, when used investigationally asinitial therapy, JANUVIA(TM) (sitagliptin) in combination withmetformin provided significant glycemic improvement and wasgenerally well tolerated over 54 weeks in patients with type 2diabetes. Additional new...

More>>