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Coiled in Medical News

Routine testing after aneurysm coiling carries low risk

...sm recurrence than clipping. As a result, maintaining a watchful eye on the coiled aneurysm, through diagnostic angiography, is imperative." Angiography i...s reviewed data from patients who had undergone angiography surveillance of coiled aneurysms between January 2002 and December 2006. The UC-led study was the ...

Study helps clarify role of vitamin D in cancer therapy

...h have been implicated in the cytoskeletal changes induced by vitamin D. The activated RhoA in turn switched on one of its targets, the rho-associated coiled kinase (ROCK), which then roused two other kinases. Each step in this nongenomic pathway was necessary to spur the genomic responses, the researchers ...

CSHL scientists correlate enzyme expression levels with chemotherapy drug response

...he drug is part of a family thought to interfere with a class of enzymes called topoisomerases. These enzymes normally act to loosen or relax tightly coiled strands of the genetic material, DNA, and in so doing play an important role in the complex, multi-step process by which cells divide and multiply. ...

Unique Simulation Training Course Ushers in New Era of Stroke Intervention

...s thread a guidewire to the clot through the carotid arteries in the neck. The wire is threaded through the clot, and when the device is deployed, the coiled wire wraps around the clot, acting like a basket and allowing the physician to pull the whole clot from the body and restore blood flow to the brain. ...

Monoclonal antibody Hb3: A marker for colon cancer progression or as a therapeutic target?

...ss spectrometry analysis. The molecular weight of CKAP4-similar protein is 62.02 kDa, including one hydrophobic region, one transmembrane domain, five coiled coils, four glycosylation sites and forty-nine phosphorylation sites. CKAP4-similar protein has high homogeneity with Np63, and the characteristic exp...

The good and bad side of anti-cancer compounds

...tor, that actively turned genes off. Enzymes known as histone deacetylases (HDACs) helped the mutant protein turn genes off by stabilizing the tightly coiled structure of DNA in chromosomes, making it inaccessible to proteins that transcribe DNA. We thought that if we could inhibit these HDACs, we could...

Mechanism of blood clot elasticity revealed in high definition

...taining a central region connected to two end regions by long, interweaving coiled chains, called alpha helices. These coiled coils were believed to give the molecule its elasticity. But how" The Il...

Engineering chimeric polypeptides to illuminate cellular redox states

...ar disulfide bonds can form, shifting the free energy minimum from the α-helix, to a clamped-coil state (similar to a helix-coil transition). The coiled state allows the two fluorescent proteins to approach closer than in the extended helix state, where they can more efficiently exchange excitation ene...

First look at an enzyme target for antibacterial and cancer drugs

...Berkeley have produced the first three-dimensional structural images of a DNA-bound Type II topoisomerase (topo II) that is responsible for untangling coiled strands of the chromosome during cell division. Preventing topo II from disentangling a cells DNA is fatal to the cell, which is why drugs that ta...

Man-Made Proteins Could Be More Useful Than Real Ones

... The researchers found that the Zwit1-F peptide folded into a bundle of coiled helices that resembled those in natural proteins. In particular, Schepartz ...he core of the structure. Other features, too, were remarkably similar to a coiled helix bundle formed of á-amino acids. “What is interesting about the a...
Coiled in Medical Technology

Neurointerventionists Expand Research to Quality of Life in Aneurysm Patients Following Minimally Invasive Coiling Treatment

... coiled Patients Compare More Closely to Normal Population... age) who were selected from their database of 248 coiled patients and who underwent the procedure in 2006 a... scores between patients who had been successfully coiled and the reference population were not significantl...

Boston Scientific Welcomes Results of Brain Aneurysm Clinical Trial

...23 percent relative reduction in risk of death for coiled patients. The percentage of patients characterize...gator for ISAT. "The risk of late bleeding from a coiled aneurysm is very low, which has been a clinically ...as a slightly greater chance of re-bleeding from a coiled aneurysm in the first five years, fewer...

New Study Proves That Minimally Invasive Aneurysm Treatment Yields Successful Long-Term Results

... aneurysms (17.5 percent) re-opened over time; these patients underwent additional coiling. Of this number, 11 aneurysms repeatedly re-opened and were coiled up to a total of six times. Re- bleeding occurred in only two patients, indicating an overall annual risk of 0.3 percent for re-bleeding after treatme...
Coiled in Medical Products

Amplatz Ultra Stiff Wire Guides - Curved Safe-T-J®

Description:...lows utilization of an extra heavy duty mandril with a smooth transition to a very flexible tip. The proximal end of this wire guide is the most rigid coiled wire guide manufactured by Cook. Supplied sterile in peel-open packages. Intended for one-time use....
Company:Cook Urological

Amplatz Ultra Stiff Wire Guides - Standard

Description:...lows utilization of an extra heavy duty mandril with a smooth transition to a very flexible tip. The proximal end of this wire guide is the most rigid coiled wire guide manufactured by Cook®. Supplied sterile in peel-open packages. Intended for one-time use....
Company:Cook Urological

BIPAL Biopsy Forceps

Description:...ed for endomyocardial biopsies. The radiopaque Cordis Disposable Biopsy Forceps consist of a 3-pull ring handle, stainless steel cutting jaws, and a coiled shaft. The flexible thumb ring rotates to accommodate any position. A spring in the handle keeps the cutting jaws closed. The jaws are opened by mov...
Company:Cordis Corporation

GENETRA™

Features:...ing from 1 to 6 cm A very small 0.35 mm profile -- compatible with a special 19-gauge delivery needle A unique, user optimized delivery system A coiled structure for flexibility ...
Company:RadioMed Corporation
Coiled in Medical Dictionary

Epididymitis

...on. ... Epididymitis is an inflammation of the coiled tube (epididymis) at the back of ... Epididym...a swelling (inflammation) of the epididymis, the coiled tube ... Epididymitis Information ... Welcom... epididymitis ?The epididymis is a long, tightly coiled tube that lies ... Epididymitis is diagnosed usi...

Epididymis

... ... a small, coiled tube called the epididymis , where sperm are stored for as long ... conn...s online patient ... Epididymitis is inflammation of the epididymis —the coiled tube that collects ... The epididymis is composed of a long convolute...

Borrelia

...t 37 known species, 12 of which are Lyme related, and an unknown number of genomic strains. Borrelia ... borrelia n. Any of various irregularly coiled helical spirochetes of the genus Borrelia , some species of which cause relapsing fever in humans, Borrelia Borrelia Scientific classificat...
Coiled in Biological News

Trio of signals converge to induce liver and pancreas cell development in the embryo

...ided by genetic regulatory proteins that attach to chromosomes, marking part of the genome to be turned on or off. But first the two meters of tightly coiled DNA inside the nucleus of every cell must be loosened a bit. The regulatory proteins help with this, exposing a small domain near the target gene. The...

April 2009 Geology and GSA Today media highlights

...nimals carried a shell on their backs. Like modern hermit crabs, these ancient pioneers had a scorpion-like body, and could stuff their abdomen into a coiled snail shell. One advantage of doing this was that the shell may have acted as a humid chamber to keep their gills moist. This would have allowed brief...

NIST-Cornell team builds world's first nanofluidic device with complex 3-D surfaces

...vice where the channels were less than 100 nanometers in depth stayed free of the particles. In the viral DNA trials, the genetic material appeared as coiled in the deeper channels and elongated in the shallower ones. These results show that the 3-D nanofluidic device successfully excluded rigid nanoparticl...

Simplicity is crucial to design optimization at nanoscale

...ns, and double stacks of two bundled proteins. Their molecular models replicate realistic molecular behavior, including hydrogen bond formation in the coiled spring-like alpha-helical proteins. "The traditional way of designing materials is to consider properties at the macro level, but a more efficient ...

Human DNA repair process recorded in action

... on call in the cell, molecules of the protein assemble into a long filament along a damaged or broken segment of DNA, where they help stretch out the coiled strands and align them with corresponding segments on the cell's second copy of the chromosome, which serves as a template for reconstruction. Because...

Snails and humans use same genes to tell right from left

...k down the ultimate cause of symmetry-breaking in snails and other organisms, and the cascade of gene activation that leads to complex shapes, such as coiled shells. Despite humans' superficial symmetry - our left and right sides appear to be mirror images - we are anything but symmetric. Most people's h...

Keeping chromosomes from cuddling up

...ry glands from normal Drosophila melanogaster fruit flies. Fruit fly salivary glands are unusual, because they have many copies of the same chromosome coiled together like a rope. Hartl said, "You can actually see chromosomes, because the cells are so huge and the chromosomes are so huge." The team i...

Chemists make beds with soft landings

...proteins called peptides are of a variety that normally take the shape of a coiled spring or helix in gas phase. The method used by PNNL's Julia Laskin and Pe...chain with the amino acid lysine, which stabilizes the helix and allows the coiled chain to be chemically attached to the surface. Working with a speciall...

RNA emerges from DNA's shadow

...e physical structure both of the membrane-bound cell nucleus and the genome coiled within it. Genes are transcribed within the nucleus and the resulting RNA m...a different reason, because the section of DNA containing their sequence is coiled locally into a loop, rather than as a branch. Quite simply, this speeds up ...

EuroDYNA takes lid off the genome

...n the Netherlands reported that the DNA molecule, which in humans and most mammals is about two metres in length but only 2 nanometres in diameter, is coiled up like a spring in a solenoid structure. In such a folded structure it behaves according to the well known Hooke's law, stating that up to a certain ...
Coiled in Biological Technology

Researchers control the assembly of nanobristles into helical clusters

...strated the fabrication of such highly ordered clusters, built from similar coiled building blocks, over multiple scales and areas. The finding has potenti...he combination of geometry and material properties that favor the adhesive, coiled self-organization of bundles and enabled us to quantify the conditions for ...

Dry adhesive based on carbon nanotubes gets stronger, with directional gripping ability

...During the pyrolytic growth of the vertically-aligned multi-walled nanotubes, the initial segments grew in random directions and formed a top layer of coiled and entangled nanotubes. This layer helped to increase the nanotube area available for contacting a surface. Qu noted that sample purity was anoth...

Clemson scientists put a (nano) spring in their step

...has shown that layers of these tiny springs called coiled carbon nanotubes, each a thousand times smaller th...as extremely resilient shock absorbers. Similar coiled carbon nanotubes have been made before, yet Clemso...esearchers say this method is unique since beds of coiled carbon nanotubes can be grown in a single step usi...

The PLSG Invests $150,000 in Coventina Healthcare Enterprises, Inc., Its Eighth Company Relocation to Pittsburgh

...tina's FDA cleared therapeutic warming device, consists of a Radio Frequency (RF) generator and a family of form-fitting garments containing helically coiled wires which deliver gentle, deep, therapeutic heating along the length of the body part during treatment. This highly efficient, longitudinal field su...
Coiled in Biological Definition

Collagen

...gen sub-units are left-handed triple helices where each strand is, further, a right-handed helix itself. Thus, tropocollagen may be considered to be a coiled coil. Another rare feature of collagen is its regular arrangement of amino acids in each of the alpha chains of the collagen sub-units. The sequence...

Keratin

...mmals , beta-keratin is present in birds and reptiles . Beta-keratin is harder than alpha-keratin. Structurally alpha-keratin have alpha-helical coiled coil structure while beta-keratin have twisted beta sheet structure. In humans, the keratin family of proteins is divided into the soft epitheli...
Coiled in Biological Dictionary

Vas deferens

... A tube that is a continuation of the epididymis. ... Online Medical Dictionary and glossary with medical definitions ... The vas deferens is a coiled duct that conveys sperm from the epididymis to the ... A duplicate vas deferens on one or both sides can be a confounding cause of ... Vas...

Spirochetes

... Spirochaetes belong to a phylum of distinctive Gram-negative bacteria, which have long, helically coiled (spiral-shaped) cells. Spirochetes are chemoheterotrophic in nature, with lengths between 5 and 250 µm and diameters... Although spirochetes ar...

Small intestine

...latively rare compared to other gastrointestinal malignancies such as gastric cancer and colorectal cancer. The small intestine is a long coiled tube located in the abdominal cavity. ... In the small intestine , the epithelial cells cover the villi and contain microvilli. ... 6.3 Small...

Seminal vesicles

...rostate with seminal vesicles and seminal ducts, viewed from in front and above. ... Each seminal vesicle consists of a single tube, coiled upon itself, and giving ... either of two elongated saclike glands that secrete their fluid contents into the ejaculatory ducts of some male mammal...

S phase

..., the cell enters the S stage, when DNA synthesis or replication occurs. At the beginning of the S stage, each chromosome is composed of one coiled DNA double helix molecule, which is called a chromatid. The enzyme DNA... S phase n. The phase of the mitotic cycle during which DNA synt...

Nucleosome

...ppropriate access to it . Nucleosomes are folded through a... nucleosome n. Any of the repeating subunits of chromatin, consisting of a DNA chain coiled around a core of histones ... 3.3 ATP-dependent nucleosome remodelling ... nucleosome . Term information. Term lineage. External references. 1...

Metaphase

...hase , from the ancient Greek μετά (between) and φάσις (stage), is a stage of mitosis in the eukaryotic cell cycle in which condensed & highly coiled chromosomes, carrying genetic information, align in the middle of the cell before being separated into each of the... (Redirected from Metaphas...

Jejunum

...g.com. Shop for Bargain Sporting Goods, Toys, Collectibles, Car Parts, Food, and the Good Things in Life. The jejunum and ileum are the greatly coiled parts of the small intestine. ... Most of the jejunum lies in the umbilical region of the abdomen, whereas the ... West Shore Endoscopy Center's ...

Ileum

...erminal ileum intubation during colonoscopy? ... The terminal ileum was successfully intubated in ... The jejunum and ileum are the greatly coiled parts of the small intestine. ... It is thicker and more vascular, and redder in living persons than the ileum . ... ileum – Dictionary of Food ...

Helix-turn-helix

... not to be confused with the... A common motif in the secondary structure of proteins, the alpha helix (α- helix ) is a right- or left-handed coiled conformation, resembling a spring, in which every backbone N-H group donates a hydrogen bond to the backbone... ... helix - turn - helix (HTH) ...
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