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Cohesin in Medical News

EuroDYNA leaves healthy genomic research ecosystem as legacy

...ous discovery of the close and important relationship between two proteins, cohesin and CTCF, in regulating the expression and transcription of genes. This sub...roteins in the cell cycle and differentiation processes. The discovery that cohesin and CTCF are intimately linked was made by the group of Jan-Michael Peters ...

Molecular glue with new effect

...scertained at the IMP for the first time ever that cohesin is necessary for the function of such insulators. ...ystematically searched the entire human genome for cohesin binding sites that is, the areas where cohesin is effective. Thus, the first genome-wide...

Gene Found for Rare Disorder May Reveal New Pathway in Mental Retardation

...dLS cases. All three genes produce proteins called cohesin proteins. cohesin proteins have long been known to play an important...s unexpectedly showed that mutated genes along the cohesin pathway also cause specific abnormalities during h...
Cohesin in Medical Technology

In Rare Disorder, a Familiar Protein Disrupts Gene Function

... one open question in biology has been, "What does cohesin do when cells are not dividing?" His team's paper ...cells to identify genes that are dysregulated when cohesin doesn't work properly. Cohesin's role in dysregula... in the NIPBL gene, which plays a role in moving cohesin onto and off chromosomes. The researchers use...
Cohesin in Biological News

Gene found for rare disorder may reveal new pathway in mental retardation

...dLS cases. All three genes produce proteins called cohesin proteins. cohesin proteins have long been known to play an important...s unexpectedly showed that mutated genes along the cohesin pathway also cause specific abnormalities during h...

What controls stickiness of 'smart' chromosomal glue

...Amon, a deeper basic knowledge of the mechanism of cohesin loss during meiosis could ultimately improve under...ccording to Amon, knowledge about the mechanism of cohesin function has remained sketchy, even though it play...part cohesins, targeting a specific subunit of the cohesin complex called Rec8. Also, she said, researchers h...

Needling Chromosomes Reveals Cell Division Secret

...sed on biochemical experiments that revealed when the "glue" protein called cohesin that holds chromatids was degraded during cell division. Also, microscopic ...uck to one another at a time when biochemical analysis could not detect any cohesin proteins in the cell. Nicklas believes that the twin chromatids may still h...
Cohesin in Biological Definition

Anaphase

...ction of M-phase cyclin dependent kinases (M-Cdks). It also cleaves securin , a protein that had been inhibiting separase . Separase then cleaves cohesin , the protein responsible for holding sister chromatids together. They immediately separate, marking the cytological onset of anaphase. After separati...

Mitosis

...omosomes (called sister chromosomes) are attached to each other at a DNA element present on every chromosome called the centromere . A protein called cohesin acts as a glue joining two sister chromosomes (a.k.a. sister chromatids) along their lengths. When chromosomes are paired up and attached, each indiv...

Mitosis

...omosomes (called sister chromosomes) are attached to each other at a DNA element present on every chromosome called the centromere . A protein called cohesin acts as a glue joining two sister chromosomes (a.k.a. sister chromatids) along their lengths. When chromosomes are paired up and attached, each indiv...
Cohesin in Biological Dictionary

Sister Chromatids

...loid organisms (like humans) inherit, one from each parent. In other... cohesin is the protein complex responsible for binding the sister chromatids du... sister chromatids attach to the same spindle pole while homologous ... cohesin is localized on paired sister chromatids and dissociates from them, as ...

Chromatid

... chromatid . ... Chromatid . One of two copies of a replicated chromosome during mitosis. Together they are called sister chromatids . ... ... cohesin in transcription] Sister chromatids are preferred over homologs as ... Sister chromatid gene conversion is a prominent double-strand break rep...
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