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Clumping in Medical News

Effient(TM) is Now Available in Pharmacies

...e options for treating heart disease given how pervasive and costly this condition is in our society." Effient helps keep blood platelets from clumping together and developing a blockage in an artery. Taking Effient along with aspirin after PCI has been shown to reduce the chances of having a cardiac ...

Finding Raises Hope for Treating ALS

...hope that treatments targeting this process could be beneficial." The finding suggests that there may be significant time to treat ALS before the clumping and symptoms appear, signaling the quickening pace of progression. But this would require development of an accurate way to diagnose ALS before sympto...

Discovery Sheds Light on Huntington's Disease

...hers said that the unclumping of mutant huntingtin proteins by rhes might cause the cell death. "Since rhes is highly found in the corpus striatum, clumping somehow protects cells in other tissues of the body from dying," Subramaniam said. The team is currently testing to see if removing rhes from mice ...

MIT's implantable device offers continuous cancer monitoring

...he target molecules. Target molecules enter the implant through a semipermeable membrane, bind to the particles and cause them to clump together. That clumping can be detected by MRI (magnetic resonance imaging). The device is made of a polymer called polyethylene, which is commonly used in orthopedic impl...

New Survey Reveals 'The Lipstick Effect' With Non-Invasive Facial Plastic Surgery Procedures

...iated with non-physician administration of injectable fillers and/or lasers included burns, asymmetrical results or misplaced fillers, and granulomas, clumping which occurs when particles form lumps that can be seen and felt beneath the skin. During the economy's downturn, there are countless non-special...

Michael J. Fox Foundation Awards $1.9 Million for Development of Non-Invasive Neuroimaging Techniques in Living Brain

...approximately $1.9 million total to six teams working to develop neuroimaging technologies that would allow scientists to non-invasively visualize the clumping of the alpha-synuclein protein in the living human brain. Such technologies would dramatically accelerate research into the cause, progression and tre...

Prasugrel Receives Unanimous Approval Recommendation from FDA Advisory Committee

... subsequent aggregation by blocking the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. Antiplatelet agents prevent platelets from clumping or sticking together, which can result in clogged arteries and may lead to heart attack or stroke. About Daiichi Sankyo A global pharma...

Researchers identify toehold for HIV's assault on brain

...e brain go into overdrive, churning out substances that attract more immune cells, and white blood cells from the body flood in and join the fray, all clumping together to form destructive entities known as multinucleated giant cells. "Suddenly the brain environment turns from nurturing to toxic, and the b...

Phase II Trial of Experimental Anti-Coagulant Reports Safety and Outcomes Data

...e-a-day schedule added to their regimen. Aspirin and thienopyridines are anti-clotting agents that interfere with platelet aggregation, which is the clumping together of these blood cells. Factor Xa inhibitors interfere with formation of the fine threads of thrombin that bind the platelets together into a b...

Battling Bacteria in the Blood: U-M Researchers Tackle Deadly Infections

...hematical Biology describes a model of this process - known as flocculation - and sets the stage for further study of treatments that might accelerate clumping or make the clumps more stable. That, in turn, might help the body fight off infection more effectively. Younger and his team have more research to ...
Clumping in Medical Technology

New Analysis Evaluated Impact of Genetic Variation on Response to Prasugrel

... subsequent aggregation by blocking the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. Antiplatelet agents prevent platelets from clumping or sticking together, which can result in clogged arteries and may lead to heart attack or stroke. About Daiichi Sankyo A global pharma in...

Parkinson's Disease Foundation Awards $300,000 in Bridge Funding for Innovative Research Projects

...ing the misfolding, or clumping, of a protein called alpha-synuclein. This clumping is believed to contribute to the cell death that leads to Parkinson's. The...known compounds to determine if any are effective in preventing the protein clumping and will examine the most promising candidates for their potential to not o...

Prasugrel Significantly Reduced New or Recurrent Heart Attacks in Both Acute and Longer-Term Settings Following PCI, Compared with Clopidogrel

... subsequent aggregation by blocking the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. Antiplatelet agents prevent platelets from clumping or sticking together, which can result in clogged arteries and may lead to heart attack or stroke. About Daiichi Sankyo Company, Limited Daiichi S...

Prasugrel Head-to-Head Study Showed Reduced Cardiovascular Events in Diabetes Patients by 30 Percent Compared with Clopidogrel

... subsequent aggregation by blocking the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. Antiplatelet agents prevent platelets from clumping or sticking together, which can result in clogged arteries and may lead to heart attack or stroke. About Daiichi Sankyo A global pharma innovator,...

Head-to-Head Study Showed Prasugrel Statistically Superior to Clopidogrel in Reducing Recurrent Cardiovascular Events

... subsequent aggregation by blocking the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. Antiplatelet agents prevent platelets from clumping or sticking together, which can result in clogged arteries and may lead to heart attack or stroke. About Daiichi Sankyo Company, Limited Daiichi S...

FDA Extends Review Period for Daiichi Sankyo, Lilly Investigative Antiplatelet Drug, Prasugrel

... subsequent aggregation by blocking the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. Antiplatelet agents prevent platelets from clumping or sticking together, which can result in clogged arteries and may lead to heart attack or stroke. About Daiichi Sankyo Company, Limited Daiichi S...

BRAVE-3 Questions Value of Abciximab in PCI for Heart Attack

... clotting. Now a new study has found that high loading doses of clopidogrel, an oral medication that inhibits blood clots by preventing platelets from clumping together, can eliminate the need for intravenous abciximab, a standard cath-lab drug that also interferes with platelets, but through a different path...

Tailored Clopidogrel Dosing Improves PCI Outcomes

...l, or loading, dose several times higher than usual is necessary to ensure the effectiveness of clopidogrel, a medication that prevents platelets from clumping together to form blood clots. The payoff for tailoring the clopidogrel dose: a significant reduction one month after PCI in the combined rates of hear...

Study Results Show Investigational Drug, Prasugrel, Cuts Risk of Stent-Related Clots by More than Half Versus Clopidogrel

... subsequent aggregation by blocking the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. Antiplatelet agents prevent platelets from clumping or sticking together, which can result in clogged arteries and may lead to heart attack or stroke. Lilly, on behalf of its alliance partner, Daiichi...

FDA Grants Priority Review for Daiichi Sankyo, Lilly Drug, prasugrel

... subsequent aggregation by blocking the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. Antiplatelet agents prevent platelets from clumping or sticking together, which can result in clogged arteries and may lead to heart attack or stroke. About Daiichi Sankyo Company, Limited Daiichi S...
Clumping in Medical Products

GonoGen™

Description:...test does not require isolated, viable or fresh cultures. After heating the specimen and two minute rotation, a positive reaction will be indicated be clumping with the detection reagent....
Company:Diagnostics Inc.

Pastorex® Staph Plus Kit

Features:... Latex agglutination Detection of clumping factor, protein A and capsular polysaccharides Red agglutination within 30 seconds Complete kit including controls and disposable cards ...
Company:Bio-Rad Laboratories
Clumping in Medical Dictionary

Blood typing

... types , Rh factor, and a blood type calculator. Type O (45%): No clumping in blood drops A or B. Type A (42%): clumping in blood drop A with anti-A antibodies ... An Rh Blood Typing (Warmin...
Clumping in Biological News

Structure of protective protein in the eye lens revealed

...read becomes an inextricable, useless tangle. Small heat shock proteins (sHsps) are a particularly important group of chaperones. They prevent the clumping of proteins under stress conditions. αB-crystallin and the related sHsp αA-crystallin are the main representatives of the sHsps found in hum...

MIT’s implantable device offers continuous cancer monitoring

...he target molecules. Target molecules enter the implant through a semipermeable membrane, bind to the particles and cause them to clump together. That clumping can be detected by MRI (magnetic resonance imaging). The device is made of a polymer called polyethylene, which is commonly used in orthopedic impl...

Redefining what it means to be a prion

...issible. When the misfolded PrP protein is introduced to healthy cells, it can convert normally-folded PrP proteins to its misfolded shape and cause a clumping cascade characteristic of prions. Over the years, researchers have identified a small number of other prions in humans and other animals, most of w...

Parkinson's Disease Foundation awards $300,000 in bridge funding for innovative research projects

...ing the misfolding, or clumping, of a protein called alpha-synuclein. This clumping is believed to contribute to the cell death that leads to Parkinson's. The...known compounds to determine if any are effective in preventing the protein clumping and will examine the most promising candidates for their potential to not o...

A novel target for therapeutics against Staph infection

...ll be fatal. Senior author Magnus Hk, Ph.D. and his colleagues carried out biochemical and structural studies to determine the binding mechanism of clumping factor A (ClfA), a surface protein that plays an important role in the pathogenesis of S. aureus. The group found that ClfA binds to the blood-clotti...

Battling bacteria in the blood: Researchers tackle deadly infections

...in urinary catheters that cause many thousands of infections each year. But clumping that occurs within the bloodstream itself is also important since it may he...n and sets the stage for further study of treatments that might accelerate clumping or make the clumps more stable. That, in turn, might help the body fight of...

The Parkinson's Disease Foundation awards $950,000 in seed grants

...e with PD. She plans to engineer these intrabodies to see if they prevent clumping of the protein alpha-synuclein, which leads to the formation of Lewy bodies... already known as a hallmark of PD. Researchers believe that destroying the clumping of alpha-synuclein may stop the disease in its tracks. Dr. Lynch is ho...

Scientists clarify a mechanism of epigenetic inheritance

...e April 8 issue of Current Biology. Inherited clumping According to CSHL professor Rob Martienssen, P...laces as the original one did. This inherited clumping of DNA, which causes genes to be expressed in dist...s are effectively turned off. Surprisingly, the clumping persists even after cells divide, although, says D...

NIST, Army researchers pave the way for anthrax spore standards

...latter yields valuable data on the biological activity of the samples; however, only viable cells are counted and counts may be underestimated if cell clumping occurs. A better approach is to measure the amount of genetic material present in the sample. This method not only measures the DNA extracted from via...

Popcorn-ball design doubles efficiency of dye-sensitized solar cells

... or beat these previous records. Instead, they focused on developing new approaches and compared the performance of a homogeneous rough surface with a clumping design. One of the main quandaries in making an efficient solar cell is the size of the grains. Smaller grains have bigger surface area per volume, an...
Clumping in Biological Technology

Citrate appears to control buckyball clumping but environmental concerns remain

Blacksburg, Va. -- Fullerenes, also fondly known as buckyballs, are showing an ugly side. Since being discovered in 1985, the hollow carbon atoms have been adapted for nanotechnology and biomedical applications ranging from electronics to carriers of imaging materials. It appears that the hydr...

Multiple Types of Heart Attacks Reduced by Prasugrel in TRITON-TIMI 38 Trial

... subsequent aggregation by blocking the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. Antiplatelet agents prevent platelets from clumping or sticking together, which can result in clogged arteries and may lead to heart attack or stroke. About Daiichi Sankyo A global pharmaceuti...

BASF Set To Commercialize pro-t-action(TM) Eliminating Caries Causing Bacteria From the Mouth

...ent, L. paracasei , in pro-t-action(TM) has the unique ability to very precisely target the caries causing bacteria and bind exclusively to them, and clumping them. When aggregated and grouped together in this way, the bacteria can be flushed out of the oral cavity by normal swallowing or rinsing. Needing to...

Brown chemists create more efficient palladium fuel cell catalysts

...estled with creating palladium nanoparticles with enough active surface area to make catalysis efficient in fuel cells while preventing particles from clumping together during the chemical processes that convert a fuel source to electricity. Two Brown University chemists have found a way to overcome those cha...

European Commission Approves EFIENT(R) (prasugrel) for Patients with Acute Coronary Syndrome Undergoing PCI

...-threatening consequences." Prasugrel works by reducing the tendency of platelets, the blood particles responsible for clotting, from sticking or clumping together. By blocking a specific receptor (P2Y12 adenosine diphosphate) on the platelet surface, prasugrel prevents platelets from clumping, which can...

Researchers show how to 'stamp' nanodevices with rubber molds

...g the DNA lengths can precisely control the distance between the particles to make them assemble into orderly arrays called superlattices, rather than clumping together at random. Metal superlattices have applications in computer memory and photonics and have unique properties in electronic circuits. The n...

Using nanotechnology to create high-performance materials

...s evenly in the plastic at the molecular level." This is difficult because nanotubes tend to stick to one another and clump together. At present, this clumping makes the new material rapidly lose its special properties. ...

Daiichi Sankyo, Lilly Submit New Drug Application for Investigational Antiplatelet Drug, Prasugrel, with U.S. Food and Drug Administration

... subsequent aggregation by blocking the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. Antiplatelet agents prevent platelets from clumping or sticking together, which can result in clogged arteries and may lead to heart attack or stroke. About Daiichi Sankyo Company, Limited Daiichi S...

TissueRuptor System

...applications demand efficient disruption of samples to ensure high yields of RNA or DNA, and to minimize the risk of clogging or clumping when using purification columns or magnetic particles. For most tissues, disruption and homogenization using the TissueRuptor gi...

The QIAGEN Guide to Animal Cell Culture

...e cells in 1x trypsinEDTA solution for extended periods of time. Do not force the cells to detach before they are ready to do so, or clumping may occur. Tip - Overly confluent cultures, senescent cells, and some cell lines may be difficult to trypsinize. While inc...
Clumping in Biological Dictionary

Telomere

...al ... telomere either (free) end of a eukaryotic chromosome; ' telomeres act as caps to keep the sticky ends of chromosomes from randomly clumping Telomere | Macmillan Genetics. Telomere summary with 4 pages of encyclopedia entries, research ... Get Telomeres (Monograph) (Cold Spring Har...
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