Clostridium

ViroPharma Announces Initiation Of Non-Toxigenic Clostridium Difficile Phase 1 Program

EXTON, Pa., Aug. 6 /PRNewswire-FirstCall/ -- ViroPharma Incorporated (Nasdaq: VPHM ) today announced that dosing has begun in the Phase 1 clinical trial for NTCD (non-toxigenic Clostridium difficile ), a novel treatment approach for preventing recurrent Clostridium difficile infections (...

Cepheid Receives FDA Clearance for First On-Demand Molecular Diagnostic Test for Clostridium difficile Infection

SUNNYVALE, Calif., July 13 /PRNewswire-FirstCall/ -- Cepheid (Nasdaq: CPHD ) today announced it has received clearance from the U.S. Food & Drug Administration (FDA) to market its Xpert(R) C. difficile test, an on-demand molecular diagnostic test designed for 45-minute detection of the bac...

Transmission of MRSA and Clostridium difficile through dogs

London, UK, 7 May 2009 In a letter to the Editor of the Journal of Hospital Infection ( http://www.elsevier.com/locate/jhin ), published by Elsevier, S. Lefebvre and J.S. Weese from the University of Guelph in Canada describe a study that investigated whether MRSA and C.difficile could be pas...

Interview with GI Experts: Discussions in Clostridium difficile

Complimentary Continuing Medical Education Virtual Lecture and Podcast VOORHEES, N.J., Feb. 26 /PRNewswire/ -- The epidemiology of Clostridium difficile infection (CDI) is changing and has been marked by increasing rates and more severe and complicated disease. Furthermore, the epidemic st...

BD Announces FDA 510(k) Clearance of Novel Molecular Assay to Diagnose Clostridium difficile Infections

SAN DIEGO, Jan. 12 /PRNewswire-FirstCall/ -- BD Diagnostics, a segment of BD (Becton, Dickinson and Company) (NYSE: BDX ), announced today it has received clearance from the U.S. Food and Drug Administration to market the BD GeneOhm(TM) Cdiff molecular assay for the rapid detection of the To...

Current Concepts in Clostridium difficile Infection: A Focus on Geriatric and Pediatric Patients

A Complimentary Continuing Medical Education Newsletter Series for Physicians VOORHEES, N.J., Dec. 17 /PRNewswire/ -- Management of Clostridium difficile infection (CDI) in geriatric and pediatric populations can be challenging and complicated. Because of the observed increase in CDI...

Clostridium in Medical Technology

Optimer Pharmaceuticals Presents Results From Fidaxomicin Phase 3 Study for the Treatment of Clostridium difficile Infection

Positive data from subgroup analysis presented at 19th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) meeting in Helsinki , Finland SAN DIEGO, May 17 /PRNewswire-FirstCall/ -- Optimer Pharmaceuticals, Inc. (Nasdaq: OPTR ) announced that the results fr...

Sanofi Pasteur Starts a Phase II Study of a Vaccine Against Clostridium Difficile

LYON, France, February 17 /PRNewswire-FirstCall/ -- Sanofi Pasteur, the vaccines division of sanofi-aventis Group (EURONEXT : SAN and NYSE : SNY), announced today that it is sponsoring a phase II clinical study of a vaccine against Clostridium difficile, which is among the most common causes o...

BD Announces CE Marking of a New Molecular Test to Diagnose Patients with Clostridium difficile Infections

BD GeneOhm(TM) Cdiff Assay Submitted for FDA Clearance SAN DIEGO, July 7 /PRNewswire-FirstCall/ -- BD Diagnostics, a segment of BD (Becton, Dickinson and Company) (NYSE: BDX ), announced today the CE marking of the BD GeneOhm(TM) Cdiff molecular assay for the rapid diagnosis of patie...

Current Concepts in Clostridium difficile Infection: A Focus on Recurrent Disease

A Complimentary Continuing Education Newsletter Series for Healthcare Professionals VOORHEES, N.J., July 1 /PRNewswire/ -- Clostridium difficile infection (CDI) is a serious condition that causes disease with a wide spectrum of severity, ranging from mild diarrhea ...

Replidyne's Investigational Antibacterial Agent REP3123 Prevents Toxin Production in Clostridium difficile

Poster to be Presented at the 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy LOUISVILLE, Colo., Sept. 19 /PRNewswire-FirstCall/ -- Replidyne, Inc. (Nasdaq: RDYN ) announced today that in preclinical studies, its antibacterial candidate REP3123 i...

Replidyne's Investigational Antibacterial Agent REP3123 Prevents Sporulation in Clostridium difficile

Poster to be Presented at the 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy LOUISVILLE, Colo., Sept. 19 /PRNewswire-FirstCall/ -- Replidyne, Inc. (Nasdaq: RDYN ) announced today that in preclinical studies, its antibacterial candidate REP3123 i...

Clostridium in Medical Products

Culture, Clostridium difficile

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Dysport® Clostridium Botulinum Type A

Description: Dysport is a simple, effective, non-surgical treatment that works by relaxing facial muscles on the forehead, thereby reducing and smoothing away frown-lines and wrinkles. Dysport is supported by over a decade of clinical experience. Dysport was developed in the United Kingdom in the early 1990s ...
Company:New Zealand Medical and Scientific Ltd

Xpect Clostridium difficile Toxin A/B Test Kit

Description: Remels newest member of the Xpect family, Xpect C. difficile Toxin A/B, detects both Toxin A and B in one rapid test. The simple-to-perform test requires no sample preparation, and results are available in 20 minutes. The Remel Xpect family of rapid diagnostic test kits includes a wide range ...
Company:Remel Inc.

VIDAS Clostridium difficile (Toxin A) assay

Description: VIDAS tests are presented in individual, ready to use form. Each test is composed of a strip and a SPR. The strip contains all the reagent required for the reaction (buffer, conjugate and substrate.) The SPR (Solid Phase Receptacle) is a plastic pippette-like device. Its inside surface is coated...
Company:bioMerieux, Inc.

Clearview C. Diff A

Description:... Clearview C. Diff A is a one-step test for the direct qualitative detection of clostridium difficile toxin A from fecal samples....
Company:Inverness Point of Care

Giardia lamblia II EIA

Description:...oclonal and monoclonal/polyclonal antibody-based ELISA tests for the detection of enteric pathogens in fecal specimens. Our line includes products for clostridium difficile, Entamoeba histolytica, Giardia, Cryptosporidium and fecal leukocyte testing....
Company:Inverness Medical Innovations

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Clostridium in Medical Dictionary

Clostridium

Clostridium is a genus of Gram-positive bacteria, belonging to the Firmicutes. They are obligate anaerobes capable of producing endospores. Individual cells are rod-shaped, which gives them their name, from the Greek kloster... Clostridium difficile, spindle, and Latin difficile, difficult)...

Toxins

... new approach is needed to link ... ... VA) (Quik Chek), and ImmunoCard Toxins A&B (Meridian Bioscience, Cincinnati, OH) (ImmunoCard) ... of clostridium difficile toxin : comparison of enzyme ... High-flux hemodialysis (which removes large toxins ) reduces the risk of premature death in many ...

Tetanus

...imals ... are caused when tetanus toxin interferes with release of ... Tetanus (lockjaw) is an infectious disease caused by the bacteria clostridium tetani. ... Tetanus occurs when a wound becomes contaminated with bacterial spores. ... Tetanus — Comprehensive overview covers symptoms, ca...

Infectious Diseases

...s ... ... for Infectious Disease Research And ... Emerging and Re-emerging Infectious Diseases ... Covers infectious diseases (such as clostridium difficile and MRSA) ... From the publishers of The New England Journal of Medicine. Keeps clinicians up-to-date on the most important research imp...

Infant botulism

...lytic illness caused by botulinum toxin, which is produced by the bacterium clostridium botulinum. The toxin enters the body in one of four ways: by colonization...s rare, the majority of ... An infant can acquire botulism by ingesting clostridium botulinum spores, which ... Infant botulism results from germinatio...

Gas gangrene

...t is a deadly form of gangrene usually caused by clostridium bacteria. It is a medical emergency. Gangrene...s gangrene occurs as a result of infection by clostridium bacteria that, under ... Gas gangrene is rar...s gangrene occurs as a result of infection by clostridium bacteria that, under ... The onset of gas gan...

Clostridium in Biological News

Genome of Clostridium botulinum reveals the background to world's deadliest toxin

The genome of the organism that produces the world’s most lethal toxin is revealed today. This toxin is the one real weapon in the genome of Clostridium botulinum and less than 2 kg — the weight of two bags of sugar — is enough to kill every person on the planet. Very small amounts of the same tox...

Antibiotics take toll on beneficial microbes in gut

...atients. They could also aid in understanding and treating inflammatory bowel disease, which affects an estimated 500,000 to 1 million Americans, and clostridium difficile , a growing and serious infection problem for hospitals. Normally, a set of thousands of different kinds of microbes lives in the gut ...

Newly discovered reactions from an old drug may lead to new antibiotics

...pting the way selenoproteins are made can halt the growth of the super bug clostridium difficile and Treponema denticola , a major contributor to gum disease. Infections of clostridium difficile (commonly known as C-diff) lead to a spectrum of illnesses rangi...

Mass Biologic Labs/UMass Med School and Medarex license C. difficile monoclonal antibody to Merck

...y human monoclonal antibody combination developed to target and neutralize clostridium difficile toxins A and B, for the treatment of C. difficile infection (C...d to both toxins A and B and protection from disease or relapse. About clostridium difficile infection (CDI) C. difficile is a spore-forming bacterium ...

Monash scientists debug superbug

...ravelled ways to genetically modify the bacterium clostridium difficile and solved the mystery surrounding its ... for more than a decade. Dr Lyras said strains of clostridium difficile are found in almost every hospital in A...tistics show that in the US, more people die from clostridium difficile infections than all other intestinal in...

Scientists unlock the secrets of C. difficile's protective shell

...he detailed structure of a protective 'jacket' that surrounds cells of the clostridium difficile superbug, and which helps the dangerous pathogen stick to human ...er analyse the areas where the two proteins link together in the layer. clostridium difficile is a bacterial pathogen that is present naturally in the gut of ...

Clostridium in Biological Technology

BioNeutral's Ygiene(TM) Hospital Grade Achieves a 100% Total Kill (Pass) Against the Life Threatening Clostridium Difficile (C.diff) Spores in Independent EPA Required Protocol Testing.

NEWARK, N.J., July 21 /PRNewswire-FirstCall/ -- BioNeutral Group, Inc. ("BioNeutral") (OTC Bulletin Board: BONU), a specialty chemical technology based Life Science Company announced today that at ATS Labs using the required EPA protocol testing, BioNeutral's Ygiene(TM) Hospital Grade Antimic...

BioNeutral's Ygiene(TM) Hospital Grade Antimicrobial Demonstrates a 99.9997% Kill Rate Against Clostridium Difficile Spores (C.diff) in Independent Lab Pre-testing Phase

NEWARK, N.J., July 9 /PRNewswire-FirstCall/ -- BioNeutral Group, Inc. ("BioNeutral") (OTC Bulletin Board: BONU), a chemical technology-based Life Science company announced today that at ATS Labs, using a Quantitative Disk Carrier test starting with 5.5 million Clostridium Difficile (C.diff) spores...

Medarex and Massachusetts Biologic Laboratories Announce Primary Objective Achieved in Phase 2 Trial of Monoclonal Antibody Combination for the Treatment of Clostridium difficile Associated Diarrhea (CDAD)

Top-line data from randomized, double-blind, placebo controlled Phase 2 clinical trial indicate statistically significant reduction in recurrences of CDAD PRINCETON, N.J. and JAMAICA PLAIN, Mass., Nov. 3 /PRNewswire-FirstCall/ -- Medarex, Inc. (Nasdaq: MEDX ) a...

Optimer Pharmaceuticals Reports Second Quarter 2009 Financial Results

...imer's fidaxomicin North American Phase 3 clinical study for patients with clostridium difficile infection at the European Congress of Clinical Microbiology and ...antibiotic therapy currently in Phase 3 worldwide clinical development for clostridium difficile infection. Prulifloxacin is an antibiotic which has completed t...

Optimer Pharmaceuticals to Present at the Canaccord Adams 29th Annual Global Growth Conference

...ates under development. Fidaxomicin, formerly known as OPT-80, is the only antibiotic therapy currently in Phase 3 worldwide clinical development for clostridium difficile infection. Prulifloxacin is an antibiotic which has completed two Phase 3 clinical trials for the treatment of travelers' diarrhea, a form...

BioNeutral's Ygiene(TM) Hospital Grade Achieves World Class Independent Test Results in Killing Life Threatening Spores/Organisms

...mely difficult test to pass, especially when starting with over one million clostridium Sporogenes spores. The rapid elimination of these health threatening microo... Perhaps the biggest challenge facing hospitals worldwide is eradication of clostridium difficile spores in the environment in a timely fashion thereby reducing or...

Clostridium in Biological Products

TargeTron Gene Knockout System from Sigma-Aldrich

Description:...t. Gene knockout using the TargeTron system has been validated in a broad range of bacterial strains such asEscherichia coli, Staphylococcus aureus, clostridium perfringens, Shigella flexneri, Salmonella typhimurium,andLactococcus lactis. The system may be modified for use in additional organisms. Each Targe...
Company:Sigma-Aldrich